Ovarian metastasis from non-small cell lung cancer with ALK and EGFR mutations: A report of two cases.


:Ovarian metastasis from non-small cell lung cancer (NSCLC) is a rare condition. The current study presents the cases of 2 female patients aged 38 and 47 years old, respectively, who were initially diagnosed with NSCLC adenocarcinoma on histology. Both patients initially presented with chest pain and a cough, and subsequently developed ovarian metastases following multiple treatments. The 38-year old patient exhibited an epidermal growth factor receptor mutation, confirmed by scorpion/amplified refractory mutation system analysis from a lung biopsy. The 47-year old exhibited an anaplastic lymphoma receptor tyrosine kinase (ALK) rearrangement, revealed by fluorescence in situ hybridization analysis of the breast tissue biopsy, confirming a diagnosis of ALK rearrangement-positive NSCLC. These patients developed ovarian metastasis in the course of the disease. The current study reports the diagnostic challenges and clinical management of the disease, and provides a review of the literature.


Oncol Lett


Oncology letters


Mushi RT,Yang Y,Cai Q,Zhang R,Wu G,Dong X




Has Abstract


2016-12-01 00:00:00














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    pub_type: 杂志文章


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    journal_title:Oncology letters

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    authors: Yang T,Mao P,Chen X,Niu X,Xu G,Bai X,Xie W

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    authors: Yoshikawa M,Iinuma H,Umemoto Y,Yanagisawa T,Matsumoto A,Jinno H

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    journal_title:Oncology letters

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    authors: Al-Qasem A,Toulimat M,Tulbah A,Elkum N,Al-Tweigeri T,Aboussekhra A

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    journal_title:Oncology letters

    pub_type: 杂志文章


    authors: Li H,Tian Z,Zhang Y,Yang Q,Shi B,Hou P,Ji M

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    journal_title:Oncology letters

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    authors: Li CY,Liang GY,Yao WZ,Sui J,Shen X,Zhang YQ,Ma SM,Ye YC,Zhang ZY,Zhang WH,Yin LH,Pu YP

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    journal_title:Oncology letters

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    authors: Hashimoto T,Kurokawa Y,Wada N,Takahashi T,Miyazaki Y,Tanaka K,Makino T,Yamasaki M,Nakajima K,Mori M,Doki Y

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    journal_title:Oncology letters

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    journal_title:Oncology letters

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    authors: Ni H,Tong R,Zou L,Song G,Cho WC

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    journal_title:Oncology letters

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    authors: Kawamura J,Sugiura F,Sukegawa Y,Yoshioka Y,Hida JI,Hazama S,Okuno K

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    journal_title:Oncology letters

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    authors: Watanabe T,Shibata M,Nishiyama H,Soeda S,Furukawa S,Gonda K,Takenoshita S,Fujimori K

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    abstract::Platinum-compound chemotherapy is known to have ototoxic side-effects. However, there is a paucity of literature examining hearing function prospectively and longitudinally in cohorts containing paediatric and adult patients treated within the same cisplatin- or carboplatin-containing treatment trial protocols. In Ger...

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    pub_type: 杂志文章


    authors: Nitz A,Kontopantelis E,Bielack S,Koscielniak E,Klingebiel T,Langer T,Paulides M

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    pub_type: 杂志文章


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    journal_title:Oncology letters

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    authors: Ohnishi Y,Yasui H,Kakudo K,Nozaki M

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    journal_title:Oncology letters

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    journal_title:Oncology letters

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    journal_title:Oncology letters

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    journal_title:Oncology letters

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    journal_title:Oncology letters

    pub_type: 杂志文章


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    journal_title:Oncology letters

    pub_type: 杂志文章


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    journal_title:Oncology letters

    pub_type: 杂志文章


    authors: Zou Y,Zhang B,Mao Y,Zhang H,Hong W

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    pub_type: 杂志文章


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    journal_title:Oncology letters

    pub_type: 杂志文章


    authors: Hu J,Hong X,Li Z,Lu Q

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    journal_title:Oncology letters

    pub_type: 杂志文章


    authors: Mantas D,Kostakis ID,Machairas N,Markopoulos C

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    journal_title:Oncology letters

    pub_type: 杂志文章


    authors: Liu S,Yu Q,Han W,Qi L,Zu X,Zeng F,Xie Y,Liu J

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    journal_title:Oncology letters

    pub_type: 杂志文章


    authors: Jiang Y,Miao J,Wang D,Zhou J,Liu B,Jiao F,Liang J,Wang Y,Fan C,Zhang Q

    更新日期:2018-04-01 00:00:00