Bioinformatics analysis to screen key genes in papillary thyroid carcinoma.

abstract：:[This corrects the article DOI: 10.3892/ol.2017.6254.]. ...

journal_title：Oncology letters

authors： Sato S,Kato T,Abe K,Hanaoka T,Yano Y,Kurosaki A,Yasuda M,Sekino T,Fujiwara K,Hasegawa K

更新日期：2017-10-01 00:00:00

abstract：:The aim of the present study was to identify genes that may serve as markers for breast cancer prognosis by constructing a gene co-expression network and mining modules associated with survival. Two gene expression datasets of breast cancer were downloaded from ArrayExpress and genes from these datasets with a coeffic...

journal_title：Oncology letters

authors： Shi H,Zhang L,Qu Y,Hou L,Wang L,Zheng M

更新日期：2017-10-01 00:00:00

abstract：:Polymorphisms of the vitamin D receptor (VDR) gene may be a risk factor for pancreatic cancer (PC). We investigated the association of two single-nucleotide polymorphisms (SNPs) of the VDR gene with PC in age- and gender-matched patients and controls. PC (n=91) and healthy control (n=80) samples were genotyped for the...

journal_title：Oncology letters

authors： Li L,Wu B,Yang L,Yin G,Wei W,Sui S,Liu J

更新日期：2013-05-01 00:00:00

abstract：:The Wnt signaling pathway plays a crucial role in human cancer development, and axis inhibition protein 2 (Axin2) is a master scaffold protein involved in Wnt signaling. Axin2 negatively regulates Wnt signaling and acts as a tumor suppressor protein. The present study evaluated the association between the Axin2 single...

journal_title：Oncology letters

authors： Ma C,Liu C,Huang P,Kaku H,Chen J,Guo K,Ueki H,Sakai A,Nasu Y,Kumon H,Shimizu K,Watanabe M

更新日期：2014-08-01 00:00:00

abstract：:Focal adhesion kinase (FAK) has long been considered to be a key regulator of growth factor receptor- and integrin-mediated signals, with pivotal roles in tumor cells through its kinase activity and scaffolding function. Increased FAK expression and activity has been observed in tumors of various origins and is often ...

journal_title：Oncology letters

authors： Li M,Hou F,Zhao J,Zhang T,Li D,Wu W,Liu X,Xu L

更新日期：2018-03-01 00:00:00

abstract：:In the present study, we analyzed the supra-additive effect of oxaliplatin in combination with gemcitabine on terminal colorectal cancer and its influence on high-mobility group box 1 (HMGB1) expression. A total of 86 patients with terminal colorectal cancer were enrolled in this study. Patients received oxaliplatin i...

journal_title：Oncology letters

authors： Wen S,Du X,Gou Y,Jiang L

更新日期：2016-11-01 00:00:00

abstract：:N6-methyladenosine (m6A) is the most abundant eukaryote mRNA modification, modulated by regulators known as epigenetic writers, erasers and readers, which are known to serve crucial roles in mRNA metabolism. However, the role of m6A during B-cell development and B-cell tumorigenesis remains poorly understood. By analy...

journal_title：Oncology letters

authors： Zhang W,He X,Hu J,Yang P,Liu C,Wang J,An R,Zhen J,Pang M,Hu K,Ke X,Zhang X,Jing H

更新日期：2019-10-01 00:00:00

abstract：:The primary goal of radiotherapy in oncology is to enhance the efficacy of tumor cell death while decreasing damage to surrounding normal cells. Positive therapeutic outcomes may be accomplished by improved targeting, precisely targeting tumor cells or protecting normal cells against radiation-induced damage. The pote...

journal_title：Oncology letters

authors： Kim W,Kang J,Lee S,Youn B

更新日期：2017-06-01 00:00:00

abstract：:The long non-coding RNA (lncRNA) plasmacytoma variant translocation 1 (PVT1) has been identified as an oncogene in numerous diseases, and aberrant lncRNA PVT1 expression has been associated with the development of cancer. However, the underlying mechanism by which lncRNA PVT1 affects cell invasion in esophageal cancer...

journal_title：Oncology letters

authors： Zheng X,Hu H,Li S

更新日期：2016-10-01 00:00:00

abstract：:Radiofrequency ablation has become an increasingly common therapeutic technique for patients with hepatocellular carcinoma or metastatic liver tumors. However, reports on the effect of percutaneous radiofrequency ablation (PRFA) on circulating tumor cells (CTCs) are limited. The present study aimed to further investig...

journal_title：Oncology letters

authors： Li Y,Huang N,Wang C,Ma H,Zhou M,Lin L,Huang Z,Sun L,Shi M,Liao W

更新日期：2018-09-01 00:00:00

abstract：:Aberrant expression of microRNAs (miRNAs) contributes to the progression and outcomes of several types of tumor, while circulating miRNAs have been reported to act as biomarkers for several types of cancer. To identify specific circulating miRNAs associated with multiple myeloma (MM), a miRNA microarray analysis was u...

journal_title：Oncology letters

authors： Jiang Y,Luan Y,Chang H,Chen G

更新日期：2018-09-01 00:00:00

abstract：:We previously reported the case of a 56-year-old male who underwent surgical treatment for gastric hepatoid adenocarcinoma and splenic metastasis. The present study reports the case of the same patient who underwent successful ex vivo hepatectomy and partial liver autotransplantation. Computed tomography scans demonst...

journal_title：Oncology letters

authors： Wang FQ,Lu Q,Yan J,Peng YY,Xie CR,Su YJ,Zhou JY,Wang BL,Zhao WX,Wang XM,Bie P,Yin ZY

更新日期：2015-05-01 00:00:00

abstract：:The aim of this study was to investigate the correlation between H-ras mutation and primary hepatocellular carcinoma (HCC) and to describe the role of H-ras mutation in carcinogenesis. Clinical samples of 69 patients were collected and the expression levels of H-ras in HCC and the surrounding normal tissues were exami...

journal_title：Oncology letters

authors： Sui G,Ma X,Liu S,Niu H,Dong Q

更新日期：2012-10-01 00:00:00

abstract：:Glucose Transporter 1 (GLUT1) belongs to the expanding mammalian facilitative glucose transporter family. Elevated GLUT1 protein expression has been observed in the majority of urothelial carcinomas, with various effects on clinicopathological parameters. Whereas malignant cells have an accelerated metabolism with inc...

journal_title：Oncology letters

authors： Reis H,Tschirdewahn S,Szarvas T,Rübben H,Schmid KW,Grabellus F

更新日期：2011-11-01 00:00:00

abstract：:Peroxiredoxin (Prx) II is an imperative member of the superfamily of peroxidases. It serves an essential role in scavenging organic hydroperoxide and H2O2. It is involved in the development of various malignant tumors. In order to investigate the significance of Prx II expressions level in gastric cancer (GC), downreg...

journal_title：Oncology letters

authors： Niu L,Liu A,Xu W,Yang L,Zhu W,Gu Y

更新日期：2018-10-01 00:00:00

abstract：:Pancreatic cancer is one of the most frequently occurring malignancies worldwide and it is the fourth most common cause of cancer-associated mortality in Western countries. Thalidomide (THD) plays an important role in tumor therapy, as it is able to promote early stage apoptosis and inhibit the process of angiogenesis...

journal_title：Oncology letters

authors： Qiao Z,Yuan J,Shen J,Wang C,He Z,Hu Y,Zhang M,Xu C

更新日期：2015-05-01 00:00:00

abstract：:The expression of human transfer ribonucleic acid (tRNA) methyltransferase 9-like (KIAA1456) protein in lung cancer tissue and its effects on certain genes involved in the proliferation, migration and invasion of lung cancer cells were investigated. Immunohistochemistry was applied to stain lung cancer tissue and adja...

journal_title：Oncology letters

authors： Wang S,Liu X,Huang J,Zhang Y,Sang C,Li T,Yuan J

更新日期：2018-09-01 00:00:00

abstract：:Breast cancer is the most prevalent cancer among women, and diagnosis and treatment represent a substantial challenge due to the lack of adequate molecular targets. It has been shown that long noncoding RNAs (lncRNAs) serve pivotal roles in regulating gene expression in tumors. The roles of long intervening noncoding ...

journal_title：Oncology letters

authors： Zhu Q,Li Y,Dong X,Yang Y,Wang H,Guo S

更新日期：2020-01-01 00:00:00

abstract：:The present study reports the clinical data of two patients with renal pelvis carcinoma and one patient with renal carcinoma who developed port-site metastasis following retroperitoneal laparoscopic surgery. The current study aimed to identify the cause and prognosis of the occurrence of port-site metastasis subsequen...

journal_title：Oncology letters

authors： Wang N,Wang K,Zhong D,Liu X,Sun JI,Lin L,Ge L,Yang BO

更新日期：2016-06-01 00:00:00

abstract：:For osteoblastoma, with its predilection for the spinal column and appendicular skeleton, the skull is an unusual site, and paranasal sinus involvement is very rare. Herein, we report on a case in which the disease was located within the sphenoid bone. To the best of our knowledge, this is the 4th reported case of ost...

journal_title：Oncology letters

authors： Kukwa W,Oziębło A,Oecińska A,Czarnecka AM,Włodarski K,Kukwa A

更新日期：2010-03-01 00:00:00

abstract：:Expression level of miR-181c in neuroblastoma children and its effect on proliferation of neuroblastoma M17 cells were investigated. Fifty-seven neuroblastoma patients admitted to Weifang People's Hospital from January 2013 to December 2017 were selected and their cancer tissues and normal adjacent tissues were obtain...

journal_title：Oncology letters

authors： Xu X,Wu J,Ren G,Hu Q

更新日期：2019-09-01 00:00:00

abstract：:The present study aimed to clarify the association between kinesin family member 11 (KIF11) and human breast cancer, and the effect of KIF11 on breast cancer cell progression. Western blot analysis, reverse transcription-quantitative polymerase chain reaction (RT-qPCR) analysis, retroviral infection, immunohistochemis...

journal_title：Oncology letters

authors： Pei YY,Li GC,Ran J,Wei FX

更新日期：2017-12-01 00:00:00

abstract：:Esophageal squamous cell carcinoma (ESCC) is one of the most common malignant tumors, and has high incidence and mortality rates, worldwide. Myelodysplastic syndrome (MDS), a disorder of hematopoietic stem or progenitor cells, results in marrow failure, which increases the risk of acute myeloid leukemia (AML). Few stu...

journal_title：Oncology letters

authors： Liu L,Liu X,Sun Y,Zeng Y,Tang X,Li X,Liu J,Xiao R

更新日期：2020-11-01 00:00:00

abstract：:Cancer is a histologically and genetically heterogeneous population of tumor cells that exhibits distinct molecular profiles determined by epigenetic alterations. P-element-induced wimpy testis (PIWI) proteins in complex with PIWI-interacting RNA (piRNA) have been previously demonstrated to be involved in epigenetic r...

journal_title：Oncology letters

authors： Litwin M,Szczepańska-Buda A,Piotrowska A,Dzięgiel P,Witkiewicz W

更新日期：2017-05-01 00:00:00

abstract：:Hepatitis B virus × protein (HBx) serves an important role in the pathogenesis of the hepatitis B virus infection. Previous studies have reported that the interaction between HBx and hepatocyte mitochondria is an important factor leading to liver cell injury and apoptosis, ultimately inducing the formation of liver ca...

journal_title：Oncology letters

authors： Ling LR,Zheng DH,Zhang ZY,Xie WH,Huang YH,Chen ZX,Wang XZ,Li D

更新日期：2020-04-01 00:00:00

abstract：:HER2 amplification occurs in ~20% of gastric cancer (GC) cases; however, in gastric and gastroesophageal junction cancer with HER2 gene amplification, trastuzumab in combination with cisplatin (DDP)-based chemotherapy has been reported to improve the oncological outcome. The aim of the present study was to evaluate th...

journal_title：Oncology letters

authors： Liu Y,Ling Y,Qi Q,Zhu M,Wan M,Zhang Y,Zhang C

更新日期：2015-02-01 00:00:00

abstract：:Thyroid carcinoma is the most prevalent endocrine neoplasm globally. In the majority of thyroid carcinoma cases, a positive prognosis is predicted following administration of the appropriate treatment. A wide range of genetic alterations present in thyroid carcinoma exert their oncogenic actions partially through the ...

journal_title：Oncology letters

authors： Jiang L,Chu H,Zheng H

更新日期：2016-04-01 00:00:00

abstract：:Clinical evidence indicates that drug resistance is a major obstacle in the treatment of breast cancer (BC). Drug resistance results in the disease being uncontrollable, and leads to high mortality rates. The aim of the present study was to investigate the chemosensitizing effect of microRNA (miR)-16 on Adriamycin (AD...

journal_title：Oncology letters

authors： Gao X,Wang M,Zhang Y,Xu Z,Ding J,Tang J

更新日期：2019-09-01 00:00:00

abstract：:Pristimerin is an active compound isolated from the traditional Chinese herbs Celastraceae and Hippocrateaceae. It has been reported to exert antitumor effects under experimental and clinical conditions; however, the antitumor effects and underlying mechanisms of pristimerin in oral cancer cells have not yet been iden...

journal_title：Oncology letters

authors： Wu H,Li L,Ai Z,Yin J,Chen L

更新日期：2019-03-01 00:00:00

abstract：:Interleukin (IL)-37, a new IL-1 family member, has received increasing attention in recent years. In the past decade, it has been determined that IL-37 is expressed in various normal cells and tissues and is regulated by inflammatory stimuli and pro-cytokines via different signal transduction pathways. Recently, it ha...

journal_title：Oncology letters

authors： Wang L,Quan Y,Yue Y,Heng X,Che F

更新日期：2018-04-01 00:00:00