Esophageal squamous cell cancer coincides with myelodysplastic syndrome/acute myelogenous leukemia: A case report and review of the literature.

abstract：:The tumor suppressor protein retinoblastoma protein-interacting zinc finger gene 1 (RIZ1) is downregulated in several types of cancer, including esophageal squamous cell carcinoma (ESCC). The present study used two in vitro methods to re-express RIZ1 in the human ESCC TE13 cell line in order to induce apoptosis. RIZ1 ...

journal_title：Oncology letters

authors： Dong S,Zhang P,Liang S,Wang S,Sun P,Wang Y

更新日期：2013-12-01 00:00:00

abstract：:Traditional Chinese medicine, based on theories developed and practiced for >2,000 years, is one of the most common complementary and alternative types of medicine currently used in the treatment of patients with breast cancer. Ruanjian Sanjie (RJSJ) decoction, is composed of four herbs, including Ban xia (Pinellia te...

journal_title：Oncology letters

authors： Zhao X,Zhao J,Hu R,Yao Q,Zhang G,Shen H,Yagüe E,Hu Y

更新日期：2017-05-01 00:00:00

abstract：:Prostate cancer is the most common form of cancer in men, with increased incidence rates observed in older individuals. Prostate cancer is primarily driven via activation of the androgen receptor (AR), the principal transcriptional factor governing prostate cancer cellular programming and its associated metabolism. On...

journal_title：Oncology letters

authors： Dan C,Zhang H,Zeng W,Huang L,Gong X,Li H,Yang E,Wang L,Yao Q

更新日期：2019-01-01 00:00:00

abstract：:Brain-specific metastasis is one of the primary causes of recurrence following complete resection of non-small cell lung cancer (NSCLC) and the underlying mechanism remains unclear. The present study was designed to investigate the correlation between C-X-C chemokine receptor type 4 (CXCR4) expression and brain-specif...

journal_title：Oncology letters

authors： Wang L,Wang Z,Liu X,Liu F

更新日期：2014-06-01 00:00:00

abstract：:[-2]pro-prostate-specific antigen (2pPSA), a proform of PSA, is a new marker in patients at risk of prostate cancer. We explored the potential role of 2pPSA in the identification of patients with metastatic progression following radical prostatectomy for prostate cancer. Seventy-six patients with biochemical (PSA) rec...

journal_title：Oncology letters

authors： Sottile A,Ortega C,Berruti A,Mangioni M,Saponaro S,Polo A,Prati V,Muto G,Aglietta M,Montemurro F

更新日期：2012-04-01 00:00:00

abstract：:Epidemiological data has demonstrated that particulate matter (PM) with an aerodynamic diameter ≤ 2.5 µm (PM2.5) is associated with cancer incidence. However, the precise mechanisms underlying PM2.5-mediated hepatocellular carcinoma cancer (HCC) migration and invasion remain unclear. The aim of the present study was t...

journal_title：Oncology letters

authors： Zhang Q,Luo Q,Yuan X,Chai L,Li D,Liu J,Lv Z

更新日期：2017-05-01 00:00:00

abstract：:Vasculogenic mimicry (VM) formation is important for invasion and metastasis of tumor cells in gastric adenocarcinoma (GAC). The present study aimed to investigate the association between signal transducer and activator of transcription-3 (STAT3), phosphor-STAT3 (p-STAT3), hypoxia-inducible factor-1α (HIF-1α) and VM f...

journal_title：Oncology letters

authors： Song YY,Sun LD,Liu ML,Liu ZL,Chen F,Zhang YZ,Zheng Y,Zhang JP

更新日期：2014-07-01 00:00:00

abstract：:Deguelin is a naturally occurring rotenoid with strong cancer chemopreventive and antitumor activities. In the present study, we investigated the antitumor activity of deguelin against MPC-11 murine myeloma cells and the possible mechanism of action in vitro. Our results revealed that deguelin inhibited the proliferat...

journal_title：Oncology letters

authors： Li Z,Wu J,Wu C,Jiang J,Zheng X,Xu B,Li M

更新日期：2012-10-01 00:00:00

abstract：:Numerous studies have suggested that microRNAs (miRNAs) potently affect hepatocarcinogenesis. However, the miRNA expression profiling in patients with hepatocellular carcinoma (HCC) of familial aggregation and hepatitis B virus (HBV) infection has not been elucidated. In the present study, the plasma miRNA expression ...

journal_title：Oncology letters

authors： Zhang EL,Gu J,Zhang ZY,Dong KS,Liang BY,Huang ZY

更新日期：2017-07-01 00:00:00

abstract：:A 72-year-old man initially presented with lumbar and right chest pain, but was later found out to also have an elevated prostate-specific antigen (PSA) level at 2,000.0 ng/ml. Further evaluation disclosed metastatic prostate cancer involving the bones and lymph nodes. The patient was initially treated with combined a...

journal_title：Oncology letters

authors： Kato T,Komiya A,Yuasa J,Kaga K,Kaga M,Kojima S,Naya Y,Isaka S

更新日期：2018-02-01 00:00:00

abstract：:Glioblastoma multiforme (GBM) was one of the first cancer types systematically studied at a genomic and transcriptomic level due to its high incidence and aggressivity; however, the detailed mechanism remains unclear, even though it is known that numerous cytokines are involved in the occurrence and development of GBM...

journal_title：Oncology letters

authors： He K,Shi L,Jiang T,Li Q,Chen Y,Meng C

更新日期：2016-10-01 00:00:00

abstract：:Gastric cancer (GC) is one of the most common malignancies and is the second leading cause of cancer-associated mortality world-wide. In the present study, the prognostic value and antitumor effects of transforming growth factor β1 (TGFβ1) and its receptors in GC were explored. The online Kaplan-Meier plotter database...

journal_title：Oncology letters

authors： Liu F,Wang H,Zhang M

更新日期：2020-09-01 00:00:00

abstract：:Expression level of miR-181c in neuroblastoma children and its effect on proliferation of neuroblastoma M17 cells were investigated. Fifty-seven neuroblastoma patients admitted to Weifang People's Hospital from January 2013 to December 2017 were selected and their cancer tissues and normal adjacent tissues were obtain...

journal_title：Oncology letters

authors： Xu X,Wu J,Ren G,Hu Q

更新日期：2019-09-01 00:00:00

abstract：:Retroperitoneal liposarcoma is a rare tumor with an incidence of 2.5 per million individuals. Early diagnosis is difficult as there is an absence of specific clinical presentations. The present case study reports a patient diagnosed with retroperitoneal liposarcoma who was treated by complete surgical resection and re...

journal_title：Oncology letters

authors： Zhang WD,Liu DR,Que RS,Zhou CB,Zhan CN,Zhao JG,Chen LI

更新日期：2015-07-01 00:00:00

abstract：:Colorectal carcinoma (CRC) is a common tumor of the digestive system with poor prognosis. Studies have shown that aberrant microRNA (miRNA) expression can affect CRC progression by regulating target genes. In the present study, we investigated the functional roles and potential mechanisms of miR-331-3p in CRC. The exp...

journal_title：Oncology letters

authors： Zhang H,Wang R,Wang M

更新日期：2019-12-01 00:00:00

abstract：:Osteosarcoma (OS) is the most common tumor of the musculoskeletal system. Recently, cold atmospheric plasma (CAP) has been regarded as a promising anti-oncogenic therapy. Previous experimental studies have demonstrated that CAP treatment results in significant growth inhibition of human sarcoma and is able to induce a...

journal_title：Oncology letters

authors： Haralambiev L,Wien L,Gelbrich N,Lange J,Bakir S,Kramer A,Burchardt M,Ekkernkamp A,Gümbel D,Stope MB

更新日期：2020-01-01 00:00:00

abstract：:The present study evaluated the association between programmed cell death ligand-1 (PD-L1) expression and long-term oncologic outcomes in colorectal cancer (CRC). PD-L1 expression was evaluated using immunohistochemistry in 175 patients who underwent surgical resection for CRC between September 1999 and August 2004. P...

journal_title：Oncology letters

authors： Bae SU,Jeong WK,Baek SK,Kim NK,Hwang I

更新日期：2018-10-01 00:00:00

abstract：:Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5) is an established cancer stem cell marker and is a target gene of the Wnt/β-catenin signaling pathway, a critical pathway in the process of tumor initiation and growth. In the present study, the mRNA expression levels of LGR5, adenomatous polyposis col...

journal_title：Oncology letters

authors： Lin YU,Wu T,Yao Q,Zi S,Cui L,Yang M,Li J

更新日期：2015-06-01 00:00:00

abstract：:Human papillomavirus (HPV) E6 and E7 oncoproteins are essential factors for HPV oncogenesis. These E6 and E7 gene products play a central role in the induction of malignant transformation by interacting with several cellular regulatory proteins such as p16(INK4a), p53 and nuclear factor κB (NF-κB). In the present stud...

journal_title：Oncology letters

authors： Senba M,Mori N,Fujita S,Jutavijittum P,Yousukh A,Toriyama K,Wada A

更新日期：2010-07-01 00:00:00

abstract：:With the growing requirement for novel prognostic biomarkers for pancreatic cancer, many studies have focused on clinical and/or genomic variables. Although many studies have been performed, carbohydrate antigen 19-9 is the only biomarker in clinical use. Therefore, the present study examined whether γ-secretase genes...

journal_title：Oncology letters

authors： Jeon YH,Ha M,Kim SW,Kim MJ,Lee CS,Oh CK,Han ME,Oh SO,Kim YH

更新日期：2019-05-01 00:00:00

abstract：:The expression levels of α-enolase, also known as enolase 1 (ENO1), in liver cancer tissues and the autoantibody levels of ENO1 in the sera of patients with liver cancer were detected to investigate the function of ENO1 in the invasion and metastasis of liver cancer, as well as its clinical diagnostic value. Small int...

journal_title：Oncology letters

authors： Zhang L,Lu T,Yang Y,Hu L

更新日期：2020-11-01 00:00:00

abstract：:Skin cancer is the deadliest type of malignant disease and causes primary mortality worldwide. Dioscin, which exists in medicinal plants, has potent anticancer effects. However, its effects on skin cancer remain unknown. In the present study, the activity and mechanism of dioscin on the human skin cancer A431 cell lin...

journal_title：Oncology letters

authors： Wang P,Wang C,Liu C

更新日期：2021-01-01 00:00:00

abstract：:The expression of human transfer ribonucleic acid (tRNA) methyltransferase 9-like (KIAA1456) protein in lung cancer tissue and its effects on certain genes involved in the proliferation, migration and invasion of lung cancer cells were investigated. Immunohistochemistry was applied to stain lung cancer tissue and adja...

journal_title：Oncology letters

authors： Wang S,Liu X,Huang J,Zhang Y,Sang C,Li T,Yuan J

更新日期：2018-09-01 00:00:00

abstract：:Anaplastic thyroid carcinoma is a significantly fatal endocrine neoplasm, with an average survival time of 4-12 months following diagnosis. The present study reports the case of a 57-year-old male patient who presented to the Bağcılar Training and Research Hospital (Istanbul, Turkey) due to swelling in the neck and di...

journal_title：Oncology letters

authors： Altinay S,Taş B,Ozen A,Süt PA

更新日期：2014-06-01 00:00:00

abstract：:We report a case of tumor lysis syndrome (TLS) in a patient with gallbladder carcinoma. TLS has not been reported in association with this type of tumor. TLS typically occurs in cases of highly proliferative hematological malignancies and small cell carcinoma. Two factors that may have contributed to TLS in this case ...

journal_title：Oncology letters

authors： Duff DJ,Haddadin S,Freter C,Papageorgiou C

更新日期：2013-04-01 00:00:00

abstract：:The management of recurrent diffuse low-grade gliomas (LGGs) is controversial. In the present study, the multidisciplinary management of 35 patients with recurrent LGGs was retrospectively analyzed. Tumor progression or recurrence was defined by clinical, radiological and/or metabolic pejorative evolution. All patient...

journal_title：Oncology letters

authors： Spitaels J,Devriendt D,Sadeghi N,Luce S,De Witte O,Goldman S,Mélot C,Lefranc F

更新日期：2017-09-01 00:00:00

abstract：:Plant secondary metabolites including alkaloids, demonstrate a complex diversity in their molecular scaffolds and exhibit tremendous pharmacological potential as anti-cancerous therapeutics. The present study aimed to evaluate the anticancer activity of a natural alkaloid, mecambridine, against human oral squamous cel...

journal_title：Oncology letters

authors： Lin N,Li Z,Wang D,Zheng K,Wu Y,Wang H

更新日期：2018-01-01 00:00:00

abstract：:Colon cancer is the second most common type of cancer in females and the third in males, worldwide. The most common sites of colon cancer metastasis are the regional lymph nodes, liver, lung, bone and brain. In this study, an extremely rare case of colon adenocarcinoma with extensive metastasis to the mediastinal lymp...

journal_title：Oncology letters

authors： El-Halabi MM,Chaaban SA,Meouchy J,Page S,Salyers WJ Jr

更新日期：2014-11-01 00:00:00

abstract：:The present study aimed to examine the impact of sarcopenia, defined as low muscle mass on computed tomography (CT), prior to sorafenib therapy on the clinical outcomes of patients with hepatocellular carcinoma (HCC) receiving sorafenib therapy. In total, 232 patients with unresectable HCC (median age, 72 years) were ...

journal_title：Oncology letters

authors： Nishikawa H,Nishijima N,Enomoto H,Sakamoto A,Nasu A,Komekado H,Nishimura T,Kita R,Kimura T,Iijima H,Nishiguchi S,Osaki Y

更新日期：2017-08-01 00:00:00

abstract：:The Janus kinase (JAK)2 gene, which is located on chromosome 9p24, is involved in the signaling transduction pathways of the hematopoietic and immune system. Mutations in the JAK2 gene have served as disease markers for myeloproliferative neoplasms (MPNs). The aim of the present study was to investigate the occurrence...

journal_title：Oncology letters

authors： Zhang SP,Li H,Lai RS

更新日期：2015-02-01 00:00:00