Ex vivo hepatectomy and partial liver autotransplantation for hepatoid adenocarcinoma: A case report.

abstract：:Colorectal cancer (CRC) is the third most common cause of cancer-associated mortality worldwide. Currently, 5-fluorouracil (5-FU) remains a widely used chemotherapeutic drug in the treatment of CRC; however, 5-FU resistance during treatment has become a common problem. Livin, a member of the inhibitor of apoptosis pro...

journal_title：Oncology letters

authors： Liu S,Li X,Li Q,Liu H,Shi Y,Zhuo H,Li C,Zhu H

更新日期：2018-05-01 00:00:00

abstract：:Interleukins (ILs) are involved in the occurrence and development of numerous types of cancer, and serve a critical role in the development of effective cancer therapeutics. The aim of the present study was to investigate the effect of IL-27 on chemotherapy resistance in lung cancer cells, and analyze its potential mo...

journal_title：Oncology letters

authors： Jiang B,Shi W,Li P,Wu Y,Li Y,Bao C

更新日期：2021-01-01 00:00:00

abstract：:Carbon dioxide (CO2) laser ablation in combination with photodynamic therapy (PDT) has previously been successfully used to treat superficial basal cell carcinoma (BCC). However, the efficacy of this treatment modality is limited in the treatment of deeper lesions and the more aggressive subtypes of BCC. In order to i...

journal_title：Oncology letters

authors： Kim SA,Lee KS,Cho JW

更新日期：2013-10-01 00:00:00

abstract：:Salivary gland carcinomas are rare tumors, representing ~0.5% of all malignancies. Myoepithelioma is also uncommon, representing ~1% of all salivary gland tumors. Myoepithelial carcinoma (MC) is even rarer, representing 0.2 to 0.6% of all salivary gland tumors. We herein report a case of MC with multiple metastases ar...

journal_title：Oncology letters

authors： Panelli Santos KCP,Matsuzaki H,Unetsubo T,Tsuyoshi S,Nagatsuka H,Asaumi JI

更新日期：2017-04-01 00:00:00

abstract：:The aim of the present study was to investigate whether an increase in cyclin-dependent kinase 2 (CDK2) activity is involved in apoptosis of human bladder cancer T24 cells induced by isoliquiritigenin (ISL). The viability of T24 cells was estimated using a sulforhodamine B assay. Cell morphological changes were examin...

journal_title：Oncology letters

authors： Si L,Yang X,Yan X,Wang Y,Zheng Q

更新日期：2017-07-01 00:00:00

abstract：:The purpose of the present study was to characterize uncommon portosystemic collateral circulation in hepatic cirrhosis. Portosystemic uncommon collateral circulation (UCC) was detected, characterized and evaluated by a combination of spiral computed tomography angiography, three-dimensional imaging angiography and el...

journal_title：Oncology letters

authors： Wu Q,Shen L,Chu J,Ma X,Jin B,Meng F,Chen J,Wang Y,Wu L,Han J,Zhang W,Ma W,Wang H,Li H

更新日期：2015-01-01 00:00:00

abstract：:Dermatofibrosarcoma protuberans (DFSP) is a relatively rare low-grade sarcoma that occasionally exhibits melanin-containing spindle cells within the tumor. Fibrosarcomatous DFSP (FS-DFSP) is a variant that is characterized by areas which are histopathologically indistinguishable from fibrosarcoma. In the present study...

journal_title：Oncology letters

authors： Ishida M,Okabe H

更新日期：2012-09-01 00:00:00

abstract：:AR-42 is a member of a novelly discovered class of phenylbutyrate-derived histone deacetylase inhibitors, and has a number of antitumor effects in a variety of tumor types; however, the role of AR-42 and its possible mechanisms have not been reported in the treatment of breast cancer. The aim of the present study was ...

journal_title：Oncology letters

authors： Zhou R,Wu J,Tang X,Wei X,Ju C,Zhang F,Sun J,Shuai D,Zhang Z,Liu Q,Lv XB

更新日期：2018-08-01 00:00:00

abstract：:To determine the radiosensitizing effect of apatinib on esophageal cancer cells, and to preliminarily investigate the underlying mechanism, KYSE-150 cells were treated with apatinib, x-ray or apatinib combined with x-ray, and compared with a blank control. It was observed that apatinib significantly inhibited vascular...

journal_title：Oncology letters

authors： Hu L,Sun F,Sun Z,Ni X,Wang J,Wang J,Zhou M,Feng Y,Kong Z,Hua Q,Yu J

更新日期：2019-02-01 00:00:00

abstract：:Ovarian endometrioid borderline tumors (EBTs) are extremely rare, and are thought to be precursors of endometrioid carcinoma, beginning as adenofibroma or endometriosis and progressing in a slow, stepwise manner. In endometrioid carcinomas, a high frequency of activating mutations in phosphatase and tensin homolog (PT...

journal_title：Oncology letters

authors： Nakamura K,Nakayama K,Ishikawa M,Minamoto T,Ishibashi T,Sato E,Sanuki K,Yamashita H,Ono R,Iida K,Sultana R,Hossain MM,Ishikawa N,Kyo S

更新日期：2018-07-01 00:00:00

abstract：:The chemokine system has been reported to be utilized and manipulated by tumor cells in order to promote local tumor growth and distant dissemination. The present study aimed to investigate the expression of three chemokine ligand-receptor axes in lung carcinoma tissues. Tumor and healthy normal tissue samples were ob...

journal_title：Oncology letters

authors： Liu Y,Wu BQ,Geng H,Xu ML,Zhong HH

更新日期：2015-09-01 00:00:00

abstract：:The aim of the present study was to investigate the expression of transactivation response RNA-binding protein (TARBP)1 and its clinical significance in human non-small-cell lung cancer (NSCLC). TARBP1 expression at the mRNA level was detected by reverse transcription-quantitative polymerase chain reaction (RT-qPCR) i...

journal_title：Oncology letters

authors： Ye J,Wang J,Zhang N,Liu Y,Tan L,Xu L

更新日期：2018-05-01 00:00:00

abstract：:Maternal embryonic leucine zipper kinase (MELK) is an important regulator in tumorigenesis of human breast cancer, and if silenced leads to programmed cell death in specific breast cancer cell lines, including MDA-MB-231 cells. In the present study, RNA interference, proliferation assay and semi-quantification of cell...

journal_title：Oncology letters

authors： Li G,Yang M,Zuo L,Wang MX

更新日期：2018-06-01 00:00:00

abstract：:Matrix metalloproteinases (MMPs) are enzymes for extracellular matrix remodeling that are involved in tumor growth, progression and metastasis. Among them, MMP-9 has been implicated in tumor angiogenesis. Tissue inhibitor of matrix metalloproteinase (TIMP)-2, a member of the family of MMP inhibitors, induces apoptosis...

journal_title：Oncology letters

authors： Wajner SM,Capp C,Brasil BA,Meurer L,Maia AL

更新日期：2014-03-01 00:00:00

abstract：:Xeroderma pigmentosum group C (XPC) is a DNA-damage-recognition gene active at the early stage of DNA repair. XPC also participates in regulation of cell-cycle checkpoint and DNA-damage-induced apoptosis. In the present study, the expression levels of genes involved in nucleotide excision repair (NER) were assessed in...

journal_title：Oncology letters

authors： Zhang Y,Cao J,Meng Y,Qu C,Shen F,Xu L

更新日期：2018-05-01 00:00:00

abstract：:Chimeric antigen receptor (CAR) T cells have an unprecedented positive curative effect for hematological malignances. Most notably, cluster of differentiation 19 (CD19) CAR T-cell therapy for pediatric acute lymphoblastic leukemia is associated with a high complete remission rate and has aroused considerable attention...

journal_title：Oncology letters

authors： Fu Z,Zhou J,Chen R,Jin Y,Ni T,Qian L,Xiao C

更新日期：2020-10-01 00:00:00

abstract：:Prognosis and treatment differences between initial and second primary chondrosarcoma (pCS) remain unknown. In the present study, patients with chondrosarcoma diagnosed between January 2004 and December 2015 were identified using the Surveillance Epidemiology and End Results database. Kaplan-Meier curves and log-rank ...

journal_title：Oncology letters

authors： Mao W,Kong M,Yu H,Wang D,Huang X,Yao X,Fan J,Geng J

更新日期：2019-07-01 00:00:00

abstract：:Glioblastoma multiforme (GBM) is the most common and malignant type of glioma, with a poor prognosis for patients. The survival time of patients varies greatly due to the complexity of the human genome, which harbors diverse oncogenic drivers. In order to identify the specific driving factors, 325 glioma samples from ...

journal_title：Oncology letters

authors： Zeng F,Wang K,Huang R,Liu Y,Zhang Y,Hu H

更新日期：2019-07-01 00:00:00

abstract：:The present study aimed to assess the feasibility, safety and efficiency of ultrasound-guided percutaneous microwave ablation (MWA) on liver metastases from colon or rectal cancer. Patients who received MWA therapy for liver metastases from colon or rectal cancer between June 2009 and May 2012 were enrolled in the stu...

journal_title：Oncology letters

authors： Wang J,Liang P,Yu J,Yu MA,Liu F,Cheng Z,Yu X

更新日期：2014-07-01 00:00:00

abstract：:Leptomeningeal metastasis (LM) is an uncommon presentation of relapse in breast cancer, which is associated with poor clinical outcomes and poor prognosis. Notably, LM most commonly occurs in breast cancer. The aim of the present review was to investigate the occurrence of LM as the primary presentation of relapse fol...

journal_title：Oncology letters

authors： Sacco K,Muhammad A,Saleem W,Alshaker H,Monzon L,Islam MR,Pchejetski D

更新日期：2016-08-01 00:00:00

abstract：:Gastric cancer is an intractable disease with a poor prognosis and limited treatment options. Its treatment remains a major clinical challenge worldwide. Ephrin-B2 is upregulated and involved in tumor growth in various types of cancer. However, the association between ephrin-B2 and prognosis of gastric cancer, and the...

journal_title：Oncology letters

authors： Yue WJ,Liu YP,Li M,Liu CX,Mou SJ,Li QK,Chen ZP

更新日期：2018-10-01 00:00:00

abstract：:An individual with a twin who has developed leukemia or non-Hodgkin lymphoma (NHL) has an increased risk of developing the same disease, particularly with monozygotic twins. The few reported pairs of twins who developed NHL had similar primary sites and pathological subtypes. Here, we present the first reported cases ...

journal_title：Oncology letters

authors： Ishibashi N,Sugaya S,Takahashi H,Nishimaki H,Nakanishi Y,Chinen Y,Maebayashi T

更新日期：2019-01-01 00:00:00

abstract：:N-myc downstream-regulated gene 1 (NDRG1) is a multifunctional protein associated with carcinogenesis and tumor progression. The function of NDRG1 in hepatocellular carcinoma (HCC) cells remains controversial. The present study investigated the role of NDRG1 in HCC as well as its molecular mechanism using a range of t...

journal_title：Oncology letters

authors： Song Y,Wu G,Zhang M,Kong Q,Du J,Zheng Y,Yue L,Cao L

更新日期：2017-05-01 00:00:00

abstract：:Colorectal cancer (CRC) is a leading cause of cancer-associated mortality worldwide; therefore, there is an emerging need for novel experimental models that allow for the identification and validation of biomarkers for CRC-specific progression. In the present study, a repeated sphere-forming assay was used as a strate...

journal_title：Oncology letters

authors： Lai PL,Chen TC,Feng CY,Lin H,Ng CH,Chen Y,Hsiao M,Lu J,Huang HC

更新日期：2020-09-01 00:00:00

abstract：:The present study aimed to investigate the effects of overexpression of interferon-induced transmembrane protein 5 (IFITM5) and IFITM5 c.-14C>T mutation on osteogenic differentiation, and the proliferation, migration and invasion of SaOS2 cells. SaOS2 cells were transfected with plasmids containing wild type IFITM5 (W...

journal_title：Oncology letters

authors： Liu BY,Lu YQ,Han F,Wang Y,Mo XK,Han JX

更新日期：2017-01-01 00:00:00

abstract：:Targeted therapy of non-small cell lung cancer (NSCLC) patients with mutations in the epidermal growth factor receptor (EGFR) gene has been associated with improved prognosis. However, there is a shortage on data from real-world clinical practice in management of EGFR-positive NSCLC patients in Poland. The present stu...

journal_title：Oncology letters

authors： Ramlau R,Krawczyk P,Dziadziuszko R,Chmielewska I,Milanowski J,Olszewski W,Stencel K,Ramlau-Piątek K,Segiet A,Skroński M,Grudny J,Chorostowska-Wynimko J

更新日期：2017-11-01 00:00:00

abstract：:Ascorbic acid (A) has been demonstrated to exhibit anti-cancer activity in association with chemotherapeutic agents. Potassium (K) is a regulator of cellular proliferation. In the present study, the biological effects of A and K bicarbonate, alone or in combination (A+K), on breast cancer cell lines were evaluated. Th...

journal_title：Oncology letters

authors： Frajese GV,Benvenuto M,Fantini M,Ambrosin E,Sacchetti P,Masuelli L,Giganti MG,Modesti A,Bei R

更新日期：2016-06-01 00:00:00

abstract：:Breast cancer is a leading cause of cancer-associated mortality in females worldwide and evidence suggests that human cytomegalovirus (HCMV) infection may be implicated in the progress of breast cancer. HCMV glycoprotein B (gB) is the most abundant envelope protein and serves an important role in host cell entry. The ...

journal_title：Oncology letters

authors： Yang R,Liang J,Xu GX,Ding LM,Huang HM,Su QZ,Yan J,Li YC

更新日期：2018-05-01 00:00:00

abstract：:For osteoblastoma, with its predilection for the spinal column and appendicular skeleton, the skull is an unusual site, and paranasal sinus involvement is very rare. Herein, we report on a case in which the disease was located within the sphenoid bone. To the best of our knowledge, this is the 4th reported case of ost...

journal_title：Oncology letters

authors： Kukwa W,Oziębło A,Oecińska A,Czarnecka AM,Włodarski K,Kukwa A

更新日期：2010-03-01 00:00:00

abstract：:Lung cancer causes over 1.6 million mortalities worldwide annually. MicroRNAs (miRs) are involved in various types of cancer-associated processes. The present study investigated the possible mechanism of miR-107 in the development of lung cancer in order to identify novel targets for clinical treatment. The expression...

journal_title：Oncology letters

authors： Cai P,Li J,Chen G,Peng B,Yu L,Zhao B,Yu Y

更新日期：2020-03-01 00:00:00