Partial response of liver metastases treated with abiraterone in castration-resistant prostate cancer: A case report.

abstract：:The evaluation of minimal residual disease (MRD) in acute leukemia (AL) is currently recognized as a potential critical tool to assess the response and relapse rate of treatments. The present study investigated serum peptides from patients with AL to identify biomarkers that would be useful in providing clinical evalu...

journal_title：Oncology letters

authors： Song W,Wang N,Li W,Wang G,Hu J,He K,Li Y,Meng Y,Chen N,Wang S,Hu L,Xu B,Wang J,Li A,Cui J

更新日期：2013-11-01 00:00:00

abstract：:Breast lumpectomy is usually performed under general or local anesthesia. To the best of our knowledge, whether conscious sedation with intranasal dexmedetomidine and local anesthesia is an effective anesthetic technique has not been studied. Thus, the present study aimed to investigate the effectiveness of conscious ...

journal_title：Oncology letters

authors： Yuan YJ,Zhou P,Xia F,Zhang XB,He SS,Guo DY,Xing YH,Zhao HW

更新日期：2020-10-01 00:00:00

abstract：:The 78-kDa glucose-regulated protein (GRP78) is a stress induced heat shock protein which, under limiting conditions, functions as a cell surface signaling receptor. Tumor cells are considered to be subjected to a physiologically stressful microenvironment due to their excessive growth. The role of GRP78 in tumor surv...

journal_title：Oncology letters

authors： Yerushalmi R,Raiter A,Nalbandyan K,Hardy B

更新日期：2015-10-01 00:00:00

abstract：:Imaging techniques of upper tract urothelial carcinoma (UTUC) are presently limited. Upconversion particles (UCPs) could be used to target tumors for imaging. The present study aimed to assess the value of a nano-UCP as a diagnostic probe for deep tumor tissue, including UTUC. Polymer-coated water-soluble UCPs were sy...

journal_title：Oncology letters

authors： Liao G,Wang L,Yu W

更新日期：2018-11-01 00:00:00

abstract：:The LIM domain only protein 2 (LMO2) is a key regulator of hematopoietic stem cell development. Expression of LMO2 has been evaluated in B-cell lymphoma, T-cell acute lymphoblastic leukemia and acute myeloid leukemia; however, information concerning its role in breakpoint cluster region/Abelson murine leukemia viral o...

journal_title：Oncology letters

authors： Aly RM,Taalab MM,Abdsalam EM,Elyamany OH,Hasan OE

更新日期：2016-03-01 00:00:00

abstract：:The aim of the present study was to analyze potential therapy targets for prostate cancer using integrated analysis of two gene expression profiles. First, gene expression profiles GSE38241 and GSE3933 were downloaded from the Gene Expression Omnibus database. Differentially expressed genes (DEGs) between prostate can...

journal_title：Oncology letters

authors： Zhao R,Wang Y,Zhang M,Gu X,Wang W,Tan J,Wei X,Jin N

更新日期：2017-11-01 00:00:00

abstract：:Central diabetes insipidus (DI) is a rare complication in patients with acute myeloid leukemia (AML), typically occurring in patients with abnormalities of chromosomes 3 or 7. The association between AML with monosomy 7 and DI has been described in a number of studies; however, DI has been rarely reported in cases of ...

journal_title：Oncology letters

authors： Ma H,Yang J,Xiang B,Jia Y

更新日期：2015-06-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a common tumor in south China. Kinesin family member 2A (KIF2A) belongs to the kinesin-13 family and is associated with the growth and invasion of a number of different types of human cancer, including ovarian, breast and prostate cancer. The aim of the present study was to evaluate t...

journal_title：Oncology letters

authors： Zhang Q,Lu D,Liu W,Ye S,Guo H,Liao T,Chen C

更新日期：2019-09-01 00:00:00

abstract：:Immune checkpoint inhibitors (ICIs) have emerged as one of the most promising therapeutic options for patients with advanced cancer. The aim of the present study was to investigate the prognostic value of somatic mutations in mismatch repair (MMR) genes in metastatic cancers after ICI treatment, as well as their assoc...

journal_title：Oncology letters

authors： Liu Y,Chen L,Zhang S,Shu Y,Qi Q,Zhu M,Peng Y,Ling Y

更新日期：2020-10-01 00:00:00

abstract：:Colon cancer is the second most common type of cancer in females and the third in males, worldwide. The most common sites of colon cancer metastasis are the regional lymph nodes, liver, lung, bone and brain. In this study, an extremely rare case of colon adenocarcinoma with extensive metastasis to the mediastinal lymp...

journal_title：Oncology letters

authors： El-Halabi MM,Chaaban SA,Meouchy J,Page S,Salyers WJ Jr

更新日期：2014-11-01 00:00:00

abstract：:Gastric cancer is one of the most common malignancies with high cancer-associated mortality rate globally. Hepcidin is the peptide hormone, which is critically important in the regulation of systemic iron homeostasis. Cumulating evidence has reported that the disturbed local expression of hepcidin may serve as a predi...

journal_title：Oncology letters

authors： Zuo E,Lu Y,Yan M,Pan X,Cheng X

更新日期：2018-02-01 00:00:00

abstract：:Programmed cell death 4 (PDCD4) is known to suppress neoplastic transformation, cell proliferation and metastasis, and to be downregulated by microRNA-21 (miR-21) in renal cell carcinoma (RCC) cell lines and tissues. The aim of the present study was to investigate the roles of and association between PDCD4 and miR-21 ...

journal_title：Oncology letters

authors： Yuan H,Xin S,Huang Y,Bao Y,Jiang H,Zhou L,Ren X,Li L,Wang Q,Zhang J

更新日期：2017-09-01 00:00:00

abstract：:Famitinib (SHR1020), a novel multi-targeted tyrosine kinase inhibitor, has antitumor activity against several solid tumors via targeting vascular endothelial growth factor receptor 2, c-Kit and platelet-derived growth factor receptor β. The present study investigated famitinib's activity against human gastric cancer c...

journal_title：Oncology letters

authors： Ge S,Zhang Q,He Q,Zou J,Liu X,Li N,Tian T,Zhu Y,Gao J,Shen L

更新日期：2016-09-01 00:00:00

abstract：:Lung cancer is one of the leading causes of cancer-associated mortality. C-reactive protein (CRP), albumin (ALB), globulin (GLB), lactate dehydrogenase (LDH), neutrophil-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have been identified as general parameters for systemic inflammatory response (SIR). Fu...

journal_title：Oncology letters

authors： Zhu J,Lian L,Qin H,Wang WJ,Ren R,Xu MD,Chen K,Duan W,Gong FR,Tao M,Zhi Q,Wu MY,Li W

更新日期：2019-02-01 00:00:00

abstract：:The study aim was to evaluate the association of the expression of serum microribonucleic acid-590 (miR-590) with the risk of lung squamous cell carcinoma (LUSC), clinicopathological staging and prognosis. A total of 237 patients with LUSC and 100 healthy volunteers (control group) were included in the study. Total RN...

journal_title：Oncology letters

authors： Ma Z,Wang Y,He B,Cui J,Zhang C,Wang H,Feng W,Wang B,Wei D,Wu Y,Zeng Y,Yu G

更新日期：2018-02-01 00:00:00

abstract：:Several previous studies have shown that mutations in B-Raf proto-oncogene (BRAF) and telomerase reverse transcriptase (TERT) can be used for the diagnosis and prognosis of papillary thyroid carcinoma (PTC). However, whether mutations in BRAF and the TERT promoter may improve the accurate identification and risk strat...

journal_title：Oncology letters

authors： Liu R,Li Y,Chen W,Cong J,Zhang Z,Ma L,Chu L,Xiao H,Zhang Y,Liu Y,Xu Y,Yu Q,Yang X,Sun C

更新日期：2020-10-01 00:00:00

abstract：:Non-small cell lung cancer is a subtype of adenocarcinoma, which has previously shown positive responses to gefitinib. The aim of the current study was to determine a clinical profile of gefitinib-induced disease controls for patients with lung adenocarcinoma. Retrospective evaluation of the clinical characteristics o...

journal_title：Oncology letters

authors： Wang Z,Han QB,Gu JL,Yu XM,Sun XJ,Lin QR,Fang J,Wang YZ,Xu YP,Mao WM

更新日期：2015-01-01 00:00:00

abstract：:Poor nutritional status is common in ovarian cancer. It is well known that the nutritional status of a patient with malignant disease is associated with survival, and that it can be assessed by serum levels of rapid turnover proteins (RTPs), such as retinol binding protein, prealbumin and transferrin. Systemic inflamm...

journal_title：Oncology letters

authors： Watanabe T,Shibata M,Nishiyama H,Soeda S,Furukawa S,Gonda K,Takenoshita S,Fujimori K

更新日期：2014-02-01 00:00:00

abstract：:The elbow is an uncommon site for malignant bone tumors. Surgical options for the reconstruction of the elbow joint are limited and technically challenging. In this study, we describe a patient with osteosarcoma of the proximal ulna treated by wide resection and reconstruction with a combined use of free vascularised ...

journal_title：Oncology letters

authors： Ogose A,Hotta T,Shibata M,Kawashima H,Endo N

更新日期：2010-01-01 00:00:00

abstract：:The present study reports a case of a 59-year-old male suffering from oligodendroglioma that metastasized to the bone marrow (BM). The metastasis was detected 5 years after craniotomy was performed for the resection of the primary tumor; however, it manifested as multiple myeloma (MM)-like bone lesions, a small M comp...

journal_title：Oncology letters

authors： Jian Y,Gao W,Wu Y,Li Y,Zhang Y,Yang G,Chen W

更新日期：2016-07-01 00:00:00

abstract：:The long non-coding RNA (lncRNA), RP11-480I12.5 is one of the most dysregulated lncRNAs, which is believed to contribute to the progression of cervical carcinoma (CC); however, the exact function of RP11-480I12.5 in human CC remains unknown. The present study aimed to investigate the function and underlying molecular ...

journal_title：Oncology letters

authors： Zhang L,Li Y,Sona L

更新日期：2020-01-01 00:00:00

abstract：:The aim of the current study was to investigate the effects of resveratrol (Res) on vascular endothelial growth factor (VEGF) expression and cell proliferation in the human osteosarcoma cell line U20S. U20S cells were treated with Res at various concentrations (0, 10, 20 and 40 μmol/l) for various times (24, 48 and 72...

journal_title：Oncology letters

authors： Liu Z,Li Y,Yang R

更新日期：2012-10-01 00:00:00

abstract：:The concentrations required for curcumin to exert its anticancer activity (IC50, 20 µM) are difficult to achieve in the blood plasma of patients, due to the low bioavailability of the compound. Therefore, much effort has been devoted to the development of curcumin analogues that exhibit stronger anticancer activity an...

journal_title：Oncology letters

authors： Zhou DY,Zhao SQ,DU ZY,Zheng XI,Zhang K

更新日期：2016-06-01 00:00:00

abstract：:DJ-1 and HSP90α play a significant role in the progression of various types of cancer and are known to be associated with phosphatase and tensin homolog deleted on chromosome 10 (PTEN), PI3K-p110α and pAkt, the signaling molecule proteins from the phosphatidylinositol 3-kinase (PI3K) pathway. However, the expression o...

journal_title：Oncology letters

authors： Lee H,Choi SK,Ro JY

更新日期：2012-03-01 00:00:00

abstract：:The present study investigated enhancement of apoptosis induction and the mechanisms underlying calcium overload on C6 glioma cells in vitro, stimulated by low-level ultrasound in combination with hematoporphyrin monomethyl ether (HMME). The optimum frequency of ultrasound was determined by 3-(4,5-dimethythiazol-2-yl)...

journal_title：Oncology letters

authors： Dai S,Xu C,Tian Y,Cheng W,Li B

更新日期：2014-10-01 00:00:00

abstract：:Expression of mineral dust-induced gene (mdig) in lung cancer NCI-H1650 cells was detected to investigate the effects of mdig on proliferation and apoptosis of NCI-H1650 cells. NCI-H1650 lung cancer cells were cultured in vitro. The expression of mdig in NCI-H1650 cells was lowered using ribonucleic acid interference ...

journal_title：Oncology letters

authors： Xu X,Cao L,Zhang Y,Lian H,Sun Z,Cui Y

更新日期：2018-12-01 00:00:00

abstract：:This study aimed to determine the relationship between human papillomavirus (HPV) and nuclear factor-κB (NF-κB) in cervical cancer using 62 tissues of cervical cancer, and to compare the findings to penile cancer. HPV-DNA integration is a crucial factor for malignant transformation in cervical cancer and can be identi...

journal_title：Oncology letters

authors： Senba M,Buziba N,Mori N,Fujita S,Morimoto K,Wada A,Toriyama K

更新日期：2011-01-01 00:00:00

abstract：:The aim of the present study was to investigate the relationship between the expression of transcription factor forkhead box C2 (FOXC2) and the clinical features of cervical cancer. A total of 66 patients with cervical cancer, 42 patients with cervical intraepithelial neoplasia (CIN) and 25 patients with cervical infl...

journal_title：Oncology letters

authors： Wang J,Yue X

更新日期：2017-12-01 00:00:00

abstract：:The present study was conducted to evaluate the methanolic extract of Piper betle leaves (MPBL) and its organic fractions with regard to antitumor activity against Ehrlich ascites carcinoma (EAC) in Swiss albino mice and to confirm their antioxidant activities. At 24 h post-intraperitoneal inoculation of tumor cells i...

journal_title：Oncology letters

authors： Alam B,Majumder R,Akter S,Lee SH

更新日期：2015-02-01 00:00:00

abstract：:The incidence of gastric cancer is high, especially in China. The present study aims to provide a novel therapeutic target for gastric cancer. Peripheral blood, cancerous and paracancerous tissues were collected from patients with gastric cancer. T-cell immunoglobulin mucin domain-3 (Tim-3) expression in T-cells was m...

journal_title：Oncology letters

authors： Yu J,Zhang H,Sun S,Sun S,Li L

更新日期：2019-02-01 00:00:00