Antihyperlipidemic effects of rhapontin and rhapontigenin from rheum undulatum in rats fed a high-cholesterol diet.

abstract：:The nor-kaurane diterpene Atractyliretin was obtained by acid hydrolysis of Atractyloside, a toxic substance isolated from ATRACTYLIS GUMMIFERA L (Compositae). On the basis of spectral (IR, (1)H-NMR, (13)C-NMR and MS) analysis and chemical degradation its structure and stereochemistry was identified as 4. ...

journal_title：Planta medica

authors： Camarda L,Ceraulo L,Ferrugia M,Pascual C,Sprio V

更新日期：1986-10-01 00:00:00

abstract：:Two indole alkaloids were isolated from the culture of Aspergillus fumigatus (strain No. CY018), an endophytic fungus harboring inside the elder leaf of Cynodon dactylon. These two chemicals were identified as fumigaclavine C and fumitremorgin C. In screening the bioactivity of these two indole alkaloids, their vasore...

journal_title：Planta medica

authors： Ma HY,Song YC,Mao YY,Jiang JH,Tan RX,Luo L

更新日期：2006-04-01 00:00:00

abstract：:Hepatocellular carcinoma is one of the leading causes of malignancy-related death in China. Its therapy in clinics is a big challenge. Ginsenoside Rh2 is one of the most notable cancer-preventing components from red ginseng and it has been reported that ginsenoside Rh2 exhibited potent cytotoxicity against human hepat...

journal_title：Planta medica

authors： Lv Q,Rong N,Liu LJ,Xu XL,Liu JT,Jin FX,Wang CM

更新日期：2016-05-01 00:00:00

abstract：:Eight iridoid glucosides have been isolated from Euphrasia rostkoviana by the combination of open column- and high performance liquid chromatography. The structure of a new compound, named eurostoside, and the identity of the others have been established by chemical transformations and spectral evidence of the compoun...

journal_title：Planta medica

authors： Salama O,Sticher O

更新日期：1983-02-01 00:00:00

abstract：:Ten new polyhydroxyolean-12-ene pentacyclic triterpenoidal saponins, named rogchaponins 1-10, were isolated from the methanolic extract of the roots of Camellia sinensis by a series of chromatographic methods (silica gel flash column and C18 MPLC followed by C18 HPLC). Their structures were established by 1D and 2D-NM...

journal_title：Planta medica

authors： Varughese T,Manir MM,Rahaman M,Kim JK,Lee BG,Moon SS

更新日期：2011-12-01 00:00:00

abstract：:Examined in vitro were the effects of some triterpenoids from Panax (Araliaceae) and Glycyrrhiza (Leguminosae) spp. on the sensitivity to daunomycin (DAU) and vinblastine (VBL) of adriamycin (ADM)-resistant P388 leukemia cells (P388/ADM), which were resistant to multiple anticancer drugs. Quasipanaxatriol, 20(S)-proto...

journal_title：Planta medica

authors： Hasegawa H,Sung JH,Matsumiya S,Uchiyama M,Inouye Y,Kasai R,Yamasaki K

更新日期：1995-10-01 00:00:00

abstract：:The distribution and level of yew constituents vary with species and tissues. In this study, a rapid and valid method incorporating ultra-fast liquid chromatography (UFLC) with MS and UV detection was developed for simultaneous determination of paclitaxel and its six semisynthesis precursors in needles and hair roots ...

journal_title：Planta medica

authors： Ge GB,Liang SC,Hu Y,Liu XB,Mao YX,Zhang YY,Luan HW,Qiu MH,Yang L

更新日期：2010-10-01 00:00:00

abstract：:In this work we studied the effect of alpha-asarone, a hypolipidemic active principle of Guatteria gaumeri Greenman, on hepatic lipid metabolism using adult rat hepatocytes cultured on a feeder layer of 3T3 cells. These cultures synthesize and secrete for at least two weeks various lipids from [14C]-acetic and [14C]-o...

journal_title：Planta medica

authors： Hernández A,López ML,Chamorro G,Mendoza-Figueroa T

更新日期：1993-04-01 00:00:00

abstract：:Olive oil has been shown to exhibit beneficial effects in the prevention of cardiovascular diseases although its molecular mechanism still remains unclear. In the present study, we investigated the effect of hydroxytyrosol (HT), a major phenolic component in olive oil and leaves from OLEA EUROPAEA L. (Oleaceae family...

journal_title：Planta medica

authors： Zrelli H,Matsuka M,Araki M,Zarrouk M,Miyazaki H

更新日期：2011-10-01 00:00:00

abstract：:A sensitive and rapid liquid chromatography-mass spectrometric method for the determination of ophiopogonin D in rat plasma was developed and validated. Chromatographic separation was performed on a C (18) column using a step gradient program with the mobile phase of 0.5 mmol/L ammonium chloride solution and acetonitr...

journal_title：Planta medica

authors： Xia CH,Sun JG,Hao HP,Wang GJ,Yan B,Gu SH,Zheng CN,Shang LL,Roberts MS

更新日期：2008-12-01 00:00:00

abstract：:The aim of this study was to determine the molecular mechanism underlying the inhibition of vascular restenosis by Radix Sophorae Flavescentis (RSF) extract after balloon dilatation injury. In a rat carotid model of balloon dilatation injury, the RSF extract showed a significant inhibitory effect on vascular restenosi...

journal_title：Planta medica

authors： Long G,Wang G,Ye L,Lin B,Wei D,Liu L,Yang L

更新日期：2009-10-01 00:00:00

abstract：:The composition and the antimicrobial activity of the essential oil from the leaves of Peumus boldus is investigated. Analyses of the oil obtained by hydrodistillation were carried out by GC and GC-MS using columns of two different stationary phases. Fractionation of the essential oil by column chromatography on silic...

journal_title：Planta medica

authors： Vila R,Valenzuela L,Bello H,Cañigueral S,Montes M,Adzet T

更新日期：1999-03-01 00:00:00

abstract：:A crude globulin fraction was isolated from the tubers of Pinellia ternata (Thunb.) Breit. Tubers of P. ternata are one of the well known Chinese traditional medicines. It is used on account of its anti-emetic effect. 6KDP was separated by means of gel filtration and chromatography on CM-Toyopearl 650 M from the crude...

journal_title：Planta medica

authors： Kurata K,Tai T,Yang Y,Kinoshita K,Koyama K,Takahashi K,Watanabe K,Nunoura Y

更新日期：1998-10-01 00:00:00

abstract：:A phytochemical study of the whole plant of TEPHROSIA HAMILTONII afforded a new flavonoid, characterised as 5, 7-dimethoxy-8-(2, 3-epoxy-3-methylbutyl)-flavanone, along with other known compounds. ...

journal_title：Planta medica

authors： Falak AH,Shoeb A

更新日期：1987-04-01 00:00:00

abstract：:Herpes simplex virus infections persist throughout the lifetime of the host and affect more than 80 % of the humans worldwide. The intensive use of available therapeutic drugs has led to undesirable effects, such as drug-resistant strains, prompting the search for new antiherpetic agents. Although diverse bioactivitie...

journal_title：Planta medica

authors： Nocchi SR,Companhoni MV,de Mello JC,Dias Filho BP,Nakamura CV,Carollo CA,Silva DB,Ueda-Nakamura T

更新日期：2017-04-01 00:00:00

abstract：:Three steroidal saponins, including astrogorgiosides A (1) and B (2) bearing acetamido-glucose moieties, and astrogorgioside C (3) with a 19-nor and bearing an aromatized B ring steroid aglycone, together with a known major saponin dimorphoside A (4), were obtained from the gorgonian Astrogorgia dumbea collected near ...

journal_title：Planta medica

authors： Lu YN,Cui P,Tian XQ,Lou LG,Fan CQ

更新日期：2016-06-01 00:00:00

abstract：:Chemical investigation of the EtOH extract of Morus alba L. (Moraceae), as guided by free radical scavenging activity, furnished 5,7-dihydroxycoumarin 7-methyl ether (1), two prenylflavones, cudraflavone B (2) and cudraflavone C (3), and oxyresveratrol (4). Compounds 1 and 4 showed superoxide scavenging effects with t...

journal_title：Planta medica

authors： Oh H,Ko EK,Jun JY,Oh MH,Park SU,Kang KH,Lee HS,Kim YC

更新日期：2002-10-01 00:00:00

abstract：:The chemical composition of the essential oil of CYMBOPOGON TRAVANCORENSIS Bor. (Poaceae) was investigated by capillary GC and GC-MS. Thirty-five compounds were identified. The oil contains mono- and sesquiterpene hydrocarbons (39.60%), oxygenated terpenes (30.45%), and phenyl propanoids (22.04%). The main constituent...

journal_title：Planta medica

authors： Mallavarapu GR,Ramesh S,Kulkarni RN,Syamasundar KV

更新日期：1992-04-01 00:00:00

abstract：:The oligomeric stilbenes (+)-alpha-viniferin (1), miyabenol C (2), and kobophenol A (3) have been isolated from Caragana sinica (Buchoz) Rehd (Leguminosae). (+)-alpha-Viniferin (1) and miyabenol C (2) exhibited protein kinase C inhibitory activity at low micromolar concentrations. (+)-alpha-Viniferin inhibited keratin...

journal_title：Planta medica

authors： Kulanthaivel P,Janzen WP,Ballas LM,Jiang JB,Hu CQ,Darges JW,Seldin JC,Cofield DJ,Adams LM

更新日期：1995-02-01 00:00:00

abstract：:The methanol extract of the defatted roots of Asparagus adscendens Roxb. yielded beta-sitosterol beta-D-glucoside, two new spirostanol glycosides (asparanin C and asparanin D) and two new furostanol glycosides (asparoside C and asparoside D). ...

journal_title：Planta medica

authors： Sharma SC,Chand R,Bhatti BS,Sati OP

更新日期：1982-09-01 00:00:00

abstract：:This article outlines the development of a simple and specific analytical method for the quantitative determination of eight coumarin constituents from the methanolic extract of the roots of Angelica gigas. The coumarin constituents present in the roots of Angelica gigas were separated using an acetonitrile (0.1 % ace...

journal_title：Planta medica

authors： Avula B,Joshi VC,Reddy V L N,Choi YW,Khan IA

更新日期：2007-11-01 00:00:00

abstract：:The accumulation of two dihydrofuroquinoline alkaloids has been studied in seventeen strains of Choisya ternata (Rutaceae) initiated from the same tree. The contents of platydesminium and balfourodinium vary in heavy proportions. The effect of some factors (age of the culture, NAA or glucose concentrations of the medi...

journal_title：Planta medica

authors： Gras M,Crèche J,Chénieux JC,Rideau M

更新日期：1982-12-01 00:00:00

abstract：:Four antiplatelet components were isolated from Arnebia euchroma. They inhibited the aggregation of washed rabbit platelets caused by collagen, arachidonic acid, platelet-activating factor, ADP, or thrombin. The potency of inhibiting collagen-induced platelet aggregation is in the following order: acetylshikonin (IC50...

journal_title：Planta medica

authors： Chang YS,Kuo SC,Weng SH,Jan SC,Ko FN,Teng CM

更新日期：1993-10-01 00:00:00

abstract：:Many herbs, and recently their biomass from in vitro cultures, are essential for the treatment of diseases. The aim of this study was to determine the optimal growth of Bacopa monnieri (water hyssop) in an in vitro culture and to examine if extracts of the B. monnieri biomass from the in vitro culture would affect hyd...

journal_title：Planta medica

authors： Łojewski M,Pomierny B,Muszyńska B,Krzyżanowska W,Budziszewska B,Szewczyk A

更新日期：2016-02-01 00:00:00

abstract：:The inhibitory action of the major constituent of Genista tridentata L. (Papilionaceae), 4',5,7-trihydroxyisoflavone (genistein), on contractions induced by agonists and electrical field stimulation of smooth muscle was analysed. Genistein inhibited twitches evoked by electrical-stimulation of strips of guinea-pig ile...

journal_title：Planta medica

authors： Herrera MD,Marhuenda E,Gibson A

更新日期：1992-08-01 00:00:00

abstract：:As part of our continuing study on the Calophyllum species, a number of coumarins, xanthones and chromene acids from different Calophyllum species of Sri Lanka were tested for inhibitory activity against the HIV-1 and its virally-encoded reverse transcriptase (RT). These compounds were found to be inactive in both the...

journal_title：Planta medica

authors： Dharmaratne HR,Tan GT,Marasinghe GP,Pezzuto JM

更新日期：2002-01-01 00:00:00

abstract：:The phenylpropanoid dibenzylbutyrolactone lignan arctigenin, a key component found in Arctium lappa, or burdock, has been reported with a variety of therapeutic effects including anticancer, anti-inflammation, and antivirus effects. Using LC/MS/MS, three novel metabolites of arctigenin, namely, arctigenic acid, arctig...

journal_title：Planta medica

authors： Gao Q,Zhang Y,Wo S,Zuo Z

更新日期：2013-04-01 00:00:00

abstract：:Eight new lupane triterpenes, including 7beta-cis-coumaroylbetulinic acid (1), 7beta-trans-coumaroylbetulinic acid (2), 7beta-cis-coumaroyl-3-epi-betulinic acid (3), 7beta-trans-coumaroyl-3-epi-betulinic acid (4), 7beta-cis-coumaroylbetulonic acid (5), 7beta-trans-coumaroylbetulonic acid (6), 7beta-hydroxybetulinaldeh...

journal_title：Planta medica

authors： Du YC,Lin AS,Wu CC,Hsieh PW,Chen YH,Chen IH,Chen SL,Yen HF,Lübken T,Chang FR,Wu YC

更新日期：2009-06-01 00:00:00

abstract：:This study aimed to elucidate the mechanisms of nuciferine (a main aporphine alkaloid of lotus leaf extract), which can induce relaxation in contracted tracheal rings. Under Ca2+-free and 2 mM Ca2+ conditions, we found that nuciferine had no effect on the resting muscle tone of tracheal rings. In contrast, nuciferine ...

journal_title：Planta medica

authors： Yang X,Yu MF,Lei J,Peng YB,Zhao P,Xue L,Chen W,Ma LQ,Liu QH,Shen J

更新日期：2018-01-01 00:00:00

abstract：:The culture medium of Beauveria amorpha Hohn. exhibited strong radical scavenging properties. Activity-directed fractionation assisted by a radical scavenging assay on TLC afforded two active compounds which were identified as 6-methyl-2,4-dihydroxyphenyl 4-O-methyl-beta-D-glucopyranoside (1) and (-)-terredionol (2). ...

journal_title：Planta medica

authors： Hu F,Schmidt K,Stoyanova S,Zengzhi L,Gräfe U,Hamburger M

更新日期：2002-01-01 00:00:00