Gut Microbiota Dysbiosis in Children with Relapsing Idiopathic Nephrotic Syndrome.

abstract：BACKGROUND:Elevated osteoprotegerin (OPG) levels are inversely correlated with creatinine clearance and end-stage renal disease in patients with diabetes, however its role in predicting decline in renal function and progression to a more advanced stage disease in the elderly general population is unknown. METHODS:This...

journal_title：American journal of nephrology

authors： Lewis JR,Lim WH,Zhu K,Wong G,Dhaliwal SS,Lim EM,Ueland T,Bollerslev J,Prince RL

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Despite a previous study showing that PINCH-1 exerts an important role in regulating TGF-β1-mediated mesenchymal transition through its interaction with integrin-linked kinase, relatively little is known about the role of PINCH in the obstructive nephropathy. METHODS:To construct a rat model of renal inters...

journal_title：American journal of nephrology

authors： Jia L,Li X,Gu Y,Cui W

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:Insulin is synthesised as a pro-hormone with an interconnecting C-peptide, cleaved during post-translational modification. This review discusses growing evidence which indicates that C-peptide is biologically active, benefiting microvascular complications associated with diabetes. METHODS:To explore th...

journal_title：American journal of nephrology

authors： Hills CE,Brunskill NJ,Squires PE

更新日期：2010-01-01 00:00:00

abstract：:There is evidence to suggest that a renal embryogenesis disorder, with an associated deficit of nephrons, may be the cause of nephropathy later in the lives of patients with Balkan endemic nephropathy (BEN). This evidence includes the renal dysplasia or hypoplasia observed in BEN patients, the high incidence of renal ...

journal_title：American journal of nephrology

authors： Nenov VD,Nenov DS

更新日期：2002-07-01 00:00:00

abstract：:We assessed blood volume (BV) in 20 edematous patients with nephrotic syndrome and in 32 subjects without renal or other disease liable to induce BV variation. Two methods were chosen, one using 131I-albumin and the other 51Cr red blood cells. Among the 20 patients, 11 presented minimal-change lesions, and 9 had histo...

journal_title：American journal of nephrology

authors： Olmer M,Berland Y,Purgus R,Schultz G

更新日期：1989-01-01 00:00:00

abstract：:Two patients with a long-standing history of familial Mediterranean fever were found to have both microscopic hematuria and proteinuria during the acute attacks. Kidney biopsies from both patients revealed diffuse mesangial proliferative glomerulonephritis with intense mesangial IgA and C3 deposits and no evidence of ...

journal_title：American journal of nephrology

authors： Said R,Nasrallah N,Hamzah Y,Tarawneh M,al-Khatib M

更新日期：1988-01-01 00:00:00

abstract：:We have demonstrated considerable variability in the volumes of different glomeruli in given individuals (individual glomerular volume: IGV) in a stereologic study of kidneys at forensic autopsy performed to investigate sudden or unexpected death in people without manifest kidney disease. We review some important asso...

journal_title：American journal of nephrology

authors： Hoy WE,Hughson MD,Diouf B,Zimanyi M,Samuel T,McNamara BJ,Douglas-Denton RN,Holden L,Mott SA,Bertram JF

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND/AIMS:The long-term renal outcomes of patients with IgA nephropathy (IgAN) who present with recurrent macroscopic hematuria (RMH) have not been described in previous studies. METHODS:Patients with biopsy-proven primary IgAN in Jinling Hospital were divided into three groups according to different patterns of...

journal_title：American journal of nephrology

authors： Le W,Liang S,Chen H,Wang S,Zhang W,Wang X,Wang J,Zeng CH,Liu ZH

更新日期：2014-01-01 00:00:00

abstract：:Hyperkalemia is a commonly encountered problem in dialysis patients with end-stage renal disease. In this study we evaluated the effect of mineralocorticoid therapy (MCT; fludrocortisone 0.1-0.3 mg per os daily) on serum potassium of hyperkalemic end-stage renal disease patients. Consecutive monthly clinical and bioch...

journal_title：American journal of nephrology

authors： Singhal PC,Desroches L,Mattana J,Abramovici M,Wagner JD,Maesaka JK

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND/AIMS:Pseudotumors of the craniovertebral junction (PTCVJ) are observed in long-term hemodialysis (HD) patients. There are neither criteria for diagnosis nor guidelines for screening. We attempted to determine magnetic resonance imaging (MRI) findings that could be used to detect PTCVJ, to determine the preva...

journal_title：American journal of nephrology

authors： Maruyama H,Tanizawa T,Uchiyama S,Higuchi T,Ei K,Oda M,Ei I,Oya M,Kishimoto H,Saito T,Miyamura S,Takano Y,Hasegawa S,Kawada K,Ueki K,Iwafuchi Y,Arakawa M

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Detection of chronic kidney disease (CKD) with urine albumin-to-creatinine ratio (UACR) among patients with hypertension (HTN) provides an opportunity for early treatment, potentially mitigating risk of CKD progression and cardiovascular complications. Differences in UACR testing patterns among racial/ethnic...

journal_title：American journal of nephrology

authors： Lee J,Chu C,Guzman D,Fontil V,Velasquez A,Powe NR,Tuot DS

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Increased mortality and morbidity are reported in association with high ultrafiltration rate (UFR) and with long dialysis recovery time (DRT). We studied the association between UFR and DRT. METHODS:This is a cross-sectional, observational study was conducted. Patients on thrice-weekly hemodialysis (HD) wit...

journal_title：American journal of nephrology

authors： Hussein WF,Arramreddy R,Sun SJ,Reiterman M,Schiller B

更新日期：2017-01-01 00:00:00

abstract：:To elucidate the prevalence and clinical implications of antineutrophil cytoplasmic antibody (ANCA) in lupus nephritis (LN), we examined ANCA by indirect immunofluorescence and by ELISA against antilactoferrin (anti-LF) and antimyeloperoxidase (anti-MPO) antibody. To discriminate perinuclear ANCA (pANCA) with antinucl...

journal_title：American journal of nephrology

authors： Chin HJ,Ahn C,Lim CS,Chung HK,Lee JG,Song YW,Lee HS,Han JS,Kim S,Lee JS

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND/AIMS:We examined the correlations between renal biopsy findings in Wegener's granulomatosis and renal function at baseline and 1 year in 22 patients who presented between 1988 and 1999. METHODS:Renal histology was independently reviewed by 2 pathologists who were masked to the clinical data. The primary out...

journal_title：American journal of nephrology

authors： Haroun MK,Stone JH,Nair R,Racusen L,Hellmann DB,Eustace JA

更新日期：2002-09-01 00:00:00

abstract：:Man-made or massive natural disasters may be followed by 'epidemics' of the muscle crush syndrome. The first descriptions of the crush syndrome were in the German-language literature following the earthquake of Messina in 1909 and World War II. On the threshold of World War II, the English-language literature was stil...

journal_title：American journal of nephrology

authors： Better OS

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Kidney failure is believed to have a negative impact on cognitive function, and cognitive impairment is common among maintenance hemodialysis (HD) patients. Previous studies have shown a beneficial effect of kidney transplantation in certain cognitive tests but not across all cognitive domains assessed. But,...

journal_title：American journal of nephrology

authors： Radić J,Ljutić D,Radić M,Kovačić V,Dodig-Ćurković K,Šain M

更新日期：2011-01-01 00:00:00

abstract：:A noninvasive method for the diagnosis of cardiac calcinosis, a life-threatening complication in hemodialysis patients with end-stage renal disease (ESRD), has not, as yet, been firmly established. We tested whether whole body scanning with 99m-technetium methylene diphosphonate (MDP) might visualize cardiac calcinosi...

journal_title：American journal of nephrology

authors： Eguchi M,Tsuchihashi K,Takizawa H,Nakahara N,Hagiwara M,Ohnishi H,Torii T,Hashimoto A,Marusaki S,Nakata T,Ura N,Shimamoto K

更新日期：2000-07-01 00:00:00

abstract：:A young woman presented with nephrotic syndrome due to membranous nephropathy and a localized form of giant lymph node hyperplasia (Castleman's disease) occurring as a large intra-abdominal mass. Five months after surgical removal of the mass, only mild proteinuria persisted. Twenty months later a second kidney biopsy...

journal_title：American journal of nephrology

authors： Ruggieri G,Barsotti P,Coppola G,Spinelli C,Balducci A,Ventola FR,d'Adamo G,Tata MV,Marinozzi V

更新日期：1990-01-01 00:00:00

abstract：:A renal transplant recipient with a remote history of end-stage renal disease due to postpartum hemolytic-uremic syndrome (HUS) presented with acute renal failure after having stable renal allograft function for 9 years. A diagnosis of thrombotic microangiopathy was made based on clinical and histologic findings at re...

journal_title：American journal of nephrology

authors： Gohh RY,Williams ME,Crosson AW,Federman M,Zambetti FX

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:End-stage renal disease (ESRD) is a disease with an aging population and a high prevalence of cognitive impairment affecting quality of life, health care costs and mortality. Structural changes in the brain with decreased white matter integrity have been observed in ESRD. Understanding the changes in cogniti...

journal_title：American journal of nephrology

authors： Gupta A,Lepping RJ,Yu AS,Perea RD,Honea RA,Johnson DK,Brooks WM,Burns JM

更新日期：2016-01-01 00:00:00

abstract：:Angiotensin-converting enzyme (ACE) inhibitor therapy has recently been shown to be effective in the treatment of post-renal transplant erythrocytosis (PTE). In an attempt to assess the effect of drug treatment on serum erythropoietin level, glomerular filtration rate, and urinary protein excretion, we prospectively e...

journal_title：American journal of nephrology

authors： Mulhern JG,Lipkowitz GS,Braden GL,Madden RL,O'Shea MH,Harvilchuck H,Guarnera JM,Germain MJ

更新日期：1995-01-01 00:00:00

abstract：:This report reviews the features of 149 cases of renal allograft rupture, while adding a detailed description of 3 more cases to the English literature. From November, 1973 to November, 1979, 3 cases of renal allograft rupture occurred in 100 renal transplants performed at Research Medical Center, Kansas City, Mo., an...

journal_title：American journal of nephrology

authors： Thukral R,Mir AR,Jacobson MP

更新日期：1982-01-01 00:00:00

abstract：:Proteinuria is characteristic of many glomerular conditions, and often exceeds 2-3 g/24 h. There are several possible routes by which such profuse proteinuria might contribute to progression of the underlying pathology, whatever its type. First, proteinuria leads to a transit of protein through glomerular structures, ...

journal_title：American journal of nephrology

authors： Cameron JS

更新日期：1990-01-01 00:00:00

abstract：:Bicarbonate dialysate is claimed to be superior to acetate for both chronic and acute hemodialysis. We compared acetate and bicarbonate dialysates in 30 acute renal failure patients during 120 dialyses. 4 patients were diabetic and 2 had liver failure. Patients were dialyzed alternating acetate and bicarbonate dialysa...

journal_title：American journal of nephrology

authors： Borges HF,Fryd DS,Rosa AA,Kjellstrand CM

更新日期：1981-01-01 00:00:00

abstract：:In 1828, Friedrich Wöhler, a German physician and chemist by training, published a paper that describes the formation of urea, known since 1773 to be a major component of mammalian urine, by combining cyanic acid and ammonium in vitro. In these experiments the synthesis of an organic compound from two inorganic molecu...

journal_title：American journal of nephrology

authors： Kinne-Saffran E,Kinne RK

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Oxidative stress (OS) and asymmetric dimethylarginine (ADMA) are accepted as nonclassical cardiovascular risk factors in end-stage renal disease patients. To clarify the role of these factors in the atherosclerotic process, we investigated if OS and ADMA are associated with common carotid artery intima media...

journal_title：American journal of nephrology

authors： Kocak H,Gumuslu S,Ermis C,Mahsereci E,Sahin E,Gocmen AY,Ersoy F,Suleymanlar G,Yakupoglu G,Tuncer M

更新日期：2008-01-01 00:00:00

abstract：:Maimonides (Moses ben Maimon) was born in 1135 in Cordoba, the son of a Jewish rabbi. After a seminomadic upbringing in Spain and North Africa during the rule of the Almohades, Maimonides settled in Fostate (Old Cairo), where he became renowned as a physician, eventually being appointed as court physician to Saladin a...

journal_title：American journal of nephrology

authors： Massry SG

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND/AIMS:The mesothelium of patients undergoing peritoneal dialysis (PD) is exposed to glucose in dialysate. Glucose metabolites 3-deoxyglucosone and advanced glycation endproducts (AGEs) in the PD fluid induce peritoneal damage. Circulating factors also affect the peritoneum in the uremic model and predialysis ...

journal_title：American journal of nephrology

authors： Hasuike Y,Moriguchi R,Hata R,Miyagawa K,Kuragano T,Aizawa M,Yamamoto S,Yanase K,Izumi M,Tanimoto T,Nakanishi T

更新日期：2007-01-01 00:00:00

abstract：:Since it was first discovered in the early 1980s, the role of atrial natriuretic peptide (ANP) in the control of fluid and electrolyte balance and blood pressure has been extensively studied in both health and disease. We report here a study of ANP and its relationship to corresponding changes in right atrial pressure...

journal_title：American journal of nephrology

authors： Tan SY,Nolan J,Craig K,Swainson CP

更新日期：1995-01-01 00:00:00

abstract：:Although the acute nephrotoxicity of cisplatin has been well documented, long-term follow-up studies are scanty. We have evaluated the renal function in 35 patients who have had completed therapy with cisplatin at least 3 months before the study. All patients had normal serum creatinine levels before chemotherapy. Eva...

journal_title：American journal of nephrology

authors： Brillet G,Deray G,Jacquiaud C,Mignot L,Bunker D,Meillet D,Raymond F,Jacobs C

更新日期：1994-01-01 00:00:00