Long-term renal effect of cisplatin in man.

abstract：BACKGROUND:More than 50% of American adolescents and adults report having used illicit drugs in their lifetime. We examined the association of lifetime opiate and cocaine use with reduced kidney function, albuminuria and rapid kidney function decline among urban-dwelling adults. METHODS:Our prospective cohort included...

journal_title：American journal of nephrology

authors： Novick T,Liu Y,Alvanzo A,Zonderman AB,Evans MK,Crews DC

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Nephrology research is expanding, and harnessing the much-needed information and data for the practice of evidence-based medicine is becoming more challenging. In this study, we used the natural language processing and text mining approach to mitigate some of these challenges. METHODS:We analyzed 17,412 abs...

journal_title：American journal of nephrology

authors： Zengul FD,Lee T,Delen D,Almehmi A,Ivankova NV,Mehta T,Topuz K

更新日期：2020-01-01 00:00:00

abstract：:To determine the effect of multiple dialyzer use on intradialytic symptoms, data from 26,592 successive dialyses on 147 patients were analyzed. Over the 26-month period of study 4,933 new dialyzers were used. All symptoms, considered together, occurred 1.3 times more frequently during the initial than during the subse...

journal_title：American journal of nephrology

authors： Robson MD,Charoenpanich R,Kant KS,Peterson DW,Flynn J,Cathey M,Pollak VE

更新日期：1986-01-01 00:00:00

abstract：:There is still debate as to the preferred extracorporeal treatment modality for severe lithium intoxication. Because lithium is readily diffusable, intermittent hemodialysis is usually performed. However, this bares the risk of a post-dialysis rebound concentration and, in the case of severe lithium poisoning collapse...

journal_title：American journal of nephrology

authors： van Bommel EF,Kalmeijer MD,Ponssen HH

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:The identification of nephrin and CD2AP, podocyte proteins which modulate the properties of glomerular barrier selectivity, has made it possible to unravel the mechanisms undergoing foot process effacement and proteinuria. Here we explored the role of nephrin and CD2AP together with the integrity of the slit...

journal_title：American journal of nephrology

authors： Gagliardini E,Benigni A,Tomasoni S,Abbate M,Kalluri R,Remuzzi G

更新日期：2003-07-01 00:00:00

abstract：:To elucidate the relationship between the renal regulation of sodium and calcium excretion at extremes of sodium intake, we studied 6 normal men ingesting a fixed, 400 mg/day calcium intake and four levels of sodium intake from 10 to 1,500 mEq/day. Serum ionized calcium was not influenced by sodium intake. Blood press...

journal_title：American journal of nephrology

authors： McCarron DA,Rankin LI,Bennett WM,Krutzik S,McClung MR,Luft FC

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Although rhabdomyolysis has been associated with acute kidney injury and mortality in the short term, the long-term consequences of an episode of rhabdomyolysis remain unknown. We sought to identify the long-term outcomes of rhabdomyolysis, including mortality, renal function, and incidence of hypertension (...

journal_title：American journal of nephrology

authors： Faulk T,Walker LE,Howard JT,Janak JC,Sosnov JA,Stewart IJ

更新日期：2018-01-01 00:00:00

abstract：:Clinical and pathologic findings are described in 14 patients whose main abnormality was an excessively thin glomerular basement membrane (GBM). The subjects were aged 11-51 years, the majority males: most were referred because of hematuria, but proteinuria was the main problem in 2, while hypertension or renal functi...

journal_title：American journal of nephrology

authors： Dische FE,Weston MJ,Parsons V

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Oxidative stress (OS) and asymmetric dimethylarginine (ADMA) are accepted as nonclassical cardiovascular risk factors in end-stage renal disease patients. To clarify the role of these factors in the atherosclerotic process, we investigated if OS and ADMA are associated with common carotid artery intima media...

journal_title：American journal of nephrology

authors： Kocak H,Gumuslu S,Ermis C,Mahsereci E,Sahin E,Gocmen AY,Ersoy F,Suleymanlar G,Yakupoglu G,Tuncer M

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Elevated osteoprotegerin (OPG) levels are inversely correlated with creatinine clearance and end-stage renal disease in patients with diabetes, however its role in predicting decline in renal function and progression to a more advanced stage disease in the elderly general population is unknown. METHODS:This...

journal_title：American journal of nephrology

authors： Lewis JR,Lim WH,Zhu K,Wong G,Dhaliwal SS,Lim EM,Ueland T,Bollerslev J,Prince RL

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Patients with diabetic nephropathy are at high risk for further progressive renal function loss. Treatments that decrease albuminuria have been linked with renal and cardiovascular protection. However, even when taking optimal treatment, residual renal and cardiovascular risk remains high which correlates wi...

journal_title：American journal of nephrology

authors： Lambers Heerspink HJ,Agarwal R,Coyne DW,Parving HH,Ritz E,Remuzzi G,Audhya P,Amdahl MJ,Andress DL,de Zeeuw D

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:There is a critical need for more noninvasive biomarkers to identify nephritis in patients with systemic lupus erythematosus (SLE). Recent studies in a model mouse and an adult SLE patient cohort suggest that anti-basement membrane antibody levels correlate well with lupus activity and kidney injury. Th...

journal_title：American journal of nephrology

authors： Orjuela A,Suwanichkul A,Canter D,Minard CG,Devaraj S,Hicks MJ,Muscal E,Wenderfer SE

更新日期：2015-01-01 00:00:00

abstract：:Man-made or massive natural disasters may be followed by 'epidemics' of the muscle crush syndrome. The first descriptions of the crush syndrome were in the German-language literature following the earthquake of Messina in 1909 and World War II. On the threshold of World War II, the English-language literature was stil...

journal_title：American journal of nephrology

authors： Better OS

更新日期：1997-01-01 00:00:00

abstract：:In hypoaldosteronemic patients with chronic renal insufficiency, administration of a mineralocorticoid steroid such as fludrocortisone can ameliorate hyperkalemia and metabolic acidosis, but this therapy is not always safe owing to the deleterious consequences of extracellular fluid volume expansion resulting from min...

journal_title：American journal of nephrology

authors： Sebastian A,Schambelan M,Sutton JM

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Placental growth factor (PlGF), a member of the vascular endothelial growth factor (VEGF) family, has recently emerged as a predictor of survival and cardiovascular risk. Along with others, we have shown an independent association between PlGF and cardiovascular events in CKD patients, but not much is known ...

journal_title：American journal of nephrology

authors： Matsui M,Samejima K,Takeda Y,Tanabe K,Morimoto K,Okamoto K,Tagawa M,Onoue K,Okayama S,Kawata H,Kawakami R,Akai Y,Saito Y

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Tacrolimus (FK) is currently widely used in transplant immunosuppression and the treatment of autoimmune diseases. However, FK induces nephrotoxicity which is characterized by functional and structural renal injury. The ubiquitous protein annexin A1 (ANXA1) has potent anti-inflammatory effects and protects a...

journal_title：American journal of nephrology

authors： Araujo LP,Truzzi RR,Mendes GE,Luz MA,Burdmann EA,Oliani SM

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Oxidative stress and inflammation are known to play central roles in the development of diabetic nephropathy (DN). Febuxostat is a novel non-purine xanthine oxidase (XO)-specific inhibitor developed to treat hyperuricemia. In this study, we investigated whether febuxostat could ameliorate DN via renoprotecti...

journal_title：American journal of nephrology

authors： Lee HJ,Jeong KH,Kim YG,Moon JY,Lee SH,Ihm CG,Sung JY,Lee TW

更新日期：2014-01-01 00:00:00

abstract：UNLABELLED:Although it is anticipated that most patients with renal insufficiency will progress towards end-stage renal disease (ESRD) there have been few population-based studies to validate this assumption. We examined serial creatinines from 3,874 anonymous patients at an urban VA medical center who had a baseline c...

journal_title：American journal of nephrology

authors： Fink JC,Salmanullah M,Blahut SA,Weir MR,Sawyer R,Henrich WL,Hise MK

更新日期：2001-09-01 00:00:00

abstract：:We analyzed routine serum potassium concentration measurements and conditions temporally associated with abnormalities in potassium concentration in outpatients on chronic hemodialysis (136 nondiabetics, 36 diabetics) and continuous ambulatory peritoneal dialysis (16 nondiabetics, 10 diabetics). The following potassiu...

journal_title：American journal of nephrology

authors： Tzamaloukas AH,Avasthi PS

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:The outcome-predictability of baseline and instantaneously changing serum calcium in hemodialysis patients has been examined. We investigated the mortality-predictability of time-averaged calcium values to reflect the 'cumulative' effect of calcium burden over time. METHODS:We employed a Cox model using up-...

journal_title：American journal of nephrology

authors： Miller JE,Kovesdy CP,Norris KC,Mehrotra R,Nissenson AR,Kopple JD,Kalantar-Zadeh K

更新日期：2010-01-01 00:00:00

abstract：:Glomerulosclerosis frequently complicates most renal diseases and is characterized by mesangial matrix accumulation. Oxidized low-density lipoprotein (Ox-LDL) could induce oxidative stress and profibrotic gene expression in mesangial cells. This article will review our current understanding of the pathogenetic mechani...

journal_title：American journal of nephrology

authors： Lee HS,Song CY

更新日期：2009-01-01 00:00:00

abstract：:Obese Zucker rats spontaneously develop lipoprotein abnormalities, proteinuria, mesangial expansion and glomerulosclerosis. Previous studies have implicated these lipoprotein abnormalities in the pathogenesis of the progressive renal injury which these rats develop. The present study was designed to examine the chrono...

journal_title：American journal of nephrology

authors： Kamanna VS,Kirschenbaum MA

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Serum creatinine (SCr) levels are decreased following traumatic amputation, leading to the overestimation of glomerular filtration rate (GFR). β-Trace protein (BTP) and β2-microglobulin (B2M) strongly correlate with measured GFR and have not been studied following amputation. We hypothesized that BTP and B2M...

journal_title：American journal of nephrology

authors： Little DJ,Yuan CM,Thurlow JS,Gounden V,Doi SQ,Pruziner A,Abbott KC,Theeler BJ,Olson SW

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:We examined the correlations between renal biopsy findings in Wegener's granulomatosis and renal function at baseline and 1 year in 22 patients who presented between 1988 and 1999. METHODS:Renal histology was independently reviewed by 2 pathologists who were masked to the clinical data. The primary out...

journal_title：American journal of nephrology

authors： Haroun MK,Stone JH,Nair R,Racusen L,Hellmann DB,Eustace JA

更新日期：2002-09-01 00:00:00

abstract：:The development of new therapies for chronic diseases, such as diabetic kidney disease (DKD), will continue to be hampered by lack of sufficient biomarkers that will provide insights and will be responsive to treatment interventions. The recent application of metabolomic technologies, such as nuclear magnetic resonanc...

journal_title：American journal of nephrology

authors： Darshi M,Van Espen B,Sharma K

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Dietary acid load (DAL) contributes to the risk of CKD and CKD progression. We sought to determine the relation of DAL to racial/ethnic differences in the risk of end-stage renal disease (ESRD) among persons with CKD. METHODS:Among 1,123 non-Hispanic black (NHB) and non-Hispanic white (NHW) National Health ...

journal_title：American journal of nephrology

authors： Crews DC,Banerjee T,Wesson DE,Morgenstern H,Saran R,Burrows NR,Williams DE,Powe NR,Centers for Disease Control and Prevention Chronic Kidney Disease Surveillance Team.

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Renal insufficiency is a well-described risk factor for perioperative morbidity and shortened survival after major vascular procedures. Due to the potential inaccuracy of serum creatinine levels alone in measuring kidney function, our aim was to determine whether estimated creatinine clearance more consisten...

journal_title：American journal of nephrology

authors： Maithel SK,Pomposelli FB,Williams M,Sheahan MG,Scovell SD,Campbell DR,LoGerfo FW,Hamdan AD

更新日期：2006-01-01 00:00:00

abstract：:Ultramorphological images and details of an uremic echinocyte are shown. The images confirm the existence of uremic echinocytes and demonstrate that atomic force microscopy can provide high-resolution images of cell surfaces. ...

journal_title：American journal of nephrology

authors： Zachée P,Boogaerts M,Snauwaert J,Hellemans L

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Persons with chronic kidney disease (CKD) represent a population prone to cardiovascular disease (CVD) but vulnerable to adverse medication effects. We assessed the impact of intensive antihypertensive therapy on the cerebrovascular and other CVD outcomes in high-risk patients with type 2 diabetes and baseli...

journal_title：American journal of nephrology

authors： Papademetriou V,Zaheer M,Doumas M,Lovato L,Applegate WB,Tsioufis C,Mottle A,Punthakee Z,Cushman WC,ACCORD Study Group.

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:In chronic hemodialysis patients, we evaluated determinants of repetitive ventricular tachyarrhythmias which included late potentials and heart rate variability. METHODS:We compared the presence of late potentials and heart rate variability obtained by ambulatory electrocardiogram (ECG), findings of ec...

journal_title：American journal of nephrology

authors： Tamura K,Tsuji H,Nishiue T,Tokunaga S,Yajima I,Higashi T,Iwasaka T

更新日期：1998-01-01 00:00:00