Oxidized low-density lipoprotein and oxidative stress in the development of glomerulosclerosis.

abstract：:This study investigated the possible beneficial effect of intraperitoneal proteolytic enzyme administration on the development of hypertension-induced renal injury in the rat model of 2-kidney 1-clip (2K1C) Goldblatt hypertension. Male Wistar rats (120-150 g) underwent either sham surgery (control, n = 5) or clipping ...

journal_title：American journal of nephrology

authors： Sebeková K,Dämmrich J,Fierlbeck W,Krivosiková Z,Paczek L,Heidland A

更新日期：1998-01-01 00:00:00

abstract：:Hepcidin is a key regulator of iron metabolism. In this study, we examined whether measurement of hepcidin is useful in assessing recombinant human erythropoietin (rHuEPO) responsiveness in regular hemodialysis (HD) patients in a cross-sectional fashion. We examined the association between serum prohepcidin, a prohorm...

journal_title：American journal of nephrology

authors： Kato A,Tsuji T,Luo J,Sakao Y,Yasuda H,Hishida A

更新日期：2008-01-01 00:00:00

abstract：:Renal disease is a common complication in malaria infection. In acute falciparum malaria renal involvement is usually mild, but in severe disease acute renal failure is a major problem. Acute renal failure has been attributed to ischaemic tubular necrosis from hypovolaemia resulting from vasodilatation due to endothel...

journal_title：American journal of nephrology

authors： Sinniah R,Lye W

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Chronic metabolic acidosis is a common metabolic disturbance and its clinical impact can be severe and extensive. The role and the change of the intrarenal renin-angiotensin system (RAS) during metabolic acidosis are uncertain, and whether acidosis can evoke inflammation remains unclear. METHODS:Male Spragu...

journal_title：American journal of nephrology

authors： Ng HY,Chen HC,Tsai YC,Yang YK,Lee CT

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:To determine the association of vancomycin with acute kidney injury (AKI) in relation to its serum concentration value and to examine the risk of AKI in patients treated with vancomycin when compared with a matched cohort of patients receiving non-glycopeptide antibiotics (linezolid/daptomycin). METHODS:Fro...

journal_title：American journal of nephrology

authors： Gyamlani G,Potukuchi PK,Thomas F,Akbilgic O,Soohoo M,Streja E,Naseer A,Sumida K,Molnar MZ,Kalantar-Zadeh K,Kovesdy CP

更新日期：2019-01-01 00:00:00

abstract：:Acute hyperammonemia is an emergent cause of central nervous system dysfunction for which renal replacement therapy is advocated. We report the successful use of continuous venovenous hemodiafiltration in this metabolic emergency, and report the calculated ammonia clearances for both continuous venovenous hemofiltrati...

journal_title：American journal of nephrology

authors： Braun MC,Welch TR

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) impairs intestinal barrier function which by allowing influx of noxious products causes systemic inflammation. We have recently shown that intestinal barrier dysfunction in CKD is due to degradation of epithelial tight junction (TJ) which is, in part, mediated by influx of urea a...

journal_title：American journal of nephrology

authors： Vaziri ND,Yuan J,Khazaeli M,Masuda Y,Ichii H,Liu S

更新日期：2013-01-01 00:00:00

abstract：:We report on a Mycobacterium marinum infection in a diabetic woman 8 years after undergoing a combined pancreas-kidney transplantation. This is, to our knowledge, the first case report on an isolated skin infection with atypical mycobacteria after simultaneous pancreas-kidney transplantation. A genetic probe categoriz...

journal_title：American journal of nephrology

authors： Schmekal B,Janko O,Zazgornik J,Schinko H,Bogner S,Syre G,Biesenbach G

更新日期：2002-09-01 00:00:00

abstract：AIMS:Although there are plenty of data about the differences in left ventricular tissue Doppler (TD) velocities by preload reduction, only a few studies regarding right ventricular function are found in the literature. We investigated the effect of intravascular volume reduction on right ventricular function by ultrafi...

journal_title：American journal of nephrology

authors： Arinc H,Gunduz H,Tamer A,Ozhan H,Akdemir R,Saglam H,Oguzhan A,Uyan C

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND/AIMS:Patients with chronic kidney disease (CKD) have a high prevalence of periodontal disease that may predispose to tooth loss and inflammation. The goal of this study was to test the hypotheses that a genetic rat model of progressive CKD would exhibit altered oral bone properties and that treatment with ei...

journal_title：American journal of nephrology

authors： Allen MR,Chen NX,Gattone VH 2nd,Moe SM

更新日期：2013-01-01 00:00:00

abstract：:Left ventricular hypertrophy (LVH) is a common finding in hypertensive autosomal dominant polycystic kidney disease (ADPKD) patients. There are few studies on the influence of blood pressure (BP) and nonhemodynamic factors on LVH in these patients. The aim of this study was to evaluate the relationship between BP, hum...

journal_title：American journal of nephrology

authors： Martinez-Vea A,Valero FA,Bardaji A,Gutierrez C,Broch M,Garcia C,Richart C,Oliver JA

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Since low-density lipoprotein (LDL) S-homocysteinylation has been recently reported to enhance atherogenicity of lipoprotein, we have investigated the levels of homocysteine (Hcy) linked to LDL in chronic proteinuric patients in which lipid abnormalities highly contribute to the excess of morbidity and morta...

journal_title：American journal of nephrology

authors： Zinellu A,Loriga G,Scanu B,Pisanu E,Sanna M,Deiana L,Satta AE,Carru C

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is a prevalent condition; however, little is known about healthcare resource utilization (HRU) by CKD patients. METHODS:This analysis included NHANES participants aged > or =18 years, with serum creatinine, urine protein, and hemoglobin measurements. We assessed the association ...

journal_title：American journal of nephrology

authors： Alexander M,Bradbury BD,Kewalramani R,Barlev A,Mohanty SA,Globe D

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:HFE protein controls iron absorption and cycling, and HFE mutations influence iron status. The aim was to evaluate the effect of the HFE genotype on the need for iron and erythropoietin in Italian hemodialysis patients. METHODS:Ninety-six prevalent patients were evaluated at the time of enrolment and p...

journal_title：American journal of nephrology

authors： Valenti L,Valenti G,Como G,Santorelli G,Dongiovanni P,Rametta R,Fracanzani AL,Tavazzi D,Messa PG,Fargion S

更新日期：2008-01-01 00:00:00

abstract：:Skin ulceration is a well-characterized thrombotic complication of the heparin-induced thrombocytopenia (HIT) syndrome. We present the case of a 73-year-old diabetic woman nearing end-stage renal failure who developed extensive upper thigh, abdominal and buttock ulceration following initiation of subcutaneous heparin ...

journal_title：American journal of nephrology

authors： Denton MD,Mauiyyedi S,Bazari H

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:In autosomal dominant polycystic kidney disease, renoprotective treatment with a vasopressin V2 receptor antagonist (V2RA) is given in a fixed dose (FD). Disease progression and drug habituation could diminish treatment efficacy. We investigated whether the renoprotective effect of the V2RA can be improved b...

journal_title：American journal of nephrology

authors： Zittema D,Versteeg IB,Gansevoort RT,van Goor H,de Heer E,Veraar KA,Peters DJ,Meijer E

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Hyperkalemia is common in patients receiving maintenance hemodialysis. However, few studies have examined the association between serum potassium level and mortality. METHODS:This study used annual cohorts of hemodialysis patients during 2007-2010. To determine hyperkalemia prevalence, monthly hyperkalemia ...

journal_title：American journal of nephrology

authors： Yusuf AA,Hu Y,Singh B,Menoyo JA,Wetmore JB

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:A poor nutritional state is associated with an increased risk of cardiovascular events in end-stage renal disease. It is unclear whether malnutrition itself can induce cardiovascular disease (CVD). We examined the impact of nutritional status on patients' arterial stiffness in peritoneal dialysis (PD) patien...

journal_title：American journal of nephrology

authors： Tang W,Cheng LT,Lu XH,Wang T

更新日期：2009-01-01 00:00:00

abstract：:A quantitative scoring method was designed to assess the extent of muscle damage. Technetium-99m pyrophosphate (99mTc-PYP) scintigraphy was performed for 9 patients experiencing crush injury in the Chichi (Taiwan) earthquake. The magnitude of muscle uptake of 99mTc-PYP was graded as follows: grade 0, less than bone ra...

journal_title：American journal of nephrology

authors： Chang HR,Kao CH,Lian JD,Shu KH,Cheng CH,Wu MJ,Chen CH

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Treatment of metabolic acidosis to target the higher serum bicarbonate level than guideline recommendation may downregulate muscle protein degradation and improve renal function among chronic kidney disease (CKD) patients. We conducted a study to test the effects of increased serum bicarbonate level on muscl...

journal_title：American journal of nephrology

authors： Kittiskulnam P,Srijaruneruang S,Chulakadabba A,Thokanit NS,Praditpornsilpa K,Tungsanga K,Eiam-Ong S

更新日期：2020-01-01 00:00:00

abstract：:Extraskeletal tumoral calcinosis occur in uremic patients with high calcium phosphorus (Ca x P) product and progressive secondary hyperparathyroidism. However, cases are also described in which this association cannot be confirmed. The influence of aluminum, vitamins D and K, alkalosis, magnesium and local lesions is ...

journal_title：American journal of nephrology

authors： Pecovnik-Balon B,Kramberger S

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:This study aimed at evaluating the after effects of a single bout of aerobic exercise on muscle sympathetic nerve activity (MSNA), peripheral vascular resistance and blood pressure (BP) in stages 2-3 chronic kidney disease (CKD) patients. We hypothesized that CKD patients present a greater decline in these v...

journal_title：American journal of nephrology

authors： Aprile DC,Oneda B,Gusmão JL,Costa LA,Forjaz CL,Mion D Jr,Tinucci T

更新日期：2016-01-01 00:00:00

abstract：UNLABELLED:Although it is anticipated that most patients with renal insufficiency will progress towards end-stage renal disease (ESRD) there have been few population-based studies to validate this assumption. We examined serial creatinines from 3,874 anonymous patients at an urban VA medical center who had a baseline c...

journal_title：American journal of nephrology

authors： Fink JC,Salmanullah M,Blahut SA,Weir MR,Sawyer R,Henrich WL,Hise MK

更新日期：2001-09-01 00:00:00

abstract：:To evaluate the therapeutic effect of recombinant human alpha-interferon (alpha-IFN) on hepatitis B virus associated glomerulonephritis (HBV-GN) and the relationship between the seroconversion of viral antigens and the change of proteinuria, the hepatitis B viral markers and urinary protein were monitored during alpha...

journal_title：American journal of nephrology

authors： Chung DR,Yang WS,Kim SB,Yu E,Chung YH,Lee Y,Park JS

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) occurs frequently in the intensive care unit. A primary cause is renal ischemia/reperfusion (I/R) injury, during which excess reactive oxygen species (ROS) are produced. ROS subsequently damage renal cells, leading to the development of AKI. Here, we investigated whether renal I/R i...

journal_title：American journal of nephrology

authors： Yamamoto S,Hagiwara S,Hidaka S,Shingu C,Goto K,Kashima K,Noguchi T

更新日期：2011-01-01 00:00:00

abstract：AIM:To study the role of the caliceal system in urine flow. METHODS:Eight patients (6 men, 2 women; mean age 42.6 +/- 7.6 years) with an upper polar renal mass (6 renal cysts; 2 hypernephromas) which did not encroach on the pelvicaliceal system were studied. After mass removal, a manometric catheter was introduced int...

journal_title：American journal of nephrology

authors： Shafik A

更新日期：1998-01-01 00:00:00

abstract：:In hypoaldosteronemic patients with chronic renal insufficiency, administration of a mineralocorticoid steroid such as fludrocortisone can ameliorate hyperkalemia and metabolic acidosis, but this therapy is not always safe owing to the deleterious consequences of extracellular fluid volume expansion resulting from min...

journal_title：American journal of nephrology

authors： Sebastian A,Schambelan M,Sutton JM

更新日期：1984-01-01 00:00:00

abstract：:To determine the prevalence and type of glomerulonephritis (GN) associated with hepatitis C virus (HCV) cirrhosis, we prospectively evaluated 28 consecutive Saudi patients with HCV cirrhosis for liver transplantation. Six patients (21%) underwent kidney biopsies for proteinuria, unexplained elevated serum creatinine o...

journal_title：American journal of nephrology

authors： Altraif IH,Abdulla AS,al Sebayel MI,Said RA,al Suhaibani MO,Jones AA

更新日期：1995-01-01 00:00:00

abstract：PURPOSE:To explore the association between CYP3A4 and CYP3A5 gene polymorphisms and blood pressure response to amlodipine among participants from the African-American Study of Kidney Disease and Hypertension Trial randomized to amlodipine (n = 164). METHODS:Cox proportional hazards models were used to determine the ri...

journal_title：American journal of nephrology

authors： Bhatnagar V,Garcia EP,O'Connor DT,Brophy VH,Alcaraz J,Richard E,Bakris GL,Middleton JP,Norris KC,Wright J,Hiremath L,Contreras G,Appel LJ,Lipkowitz MS,AASK Study Investigators.

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Death with a functioning graft (DWF) has been reported as a major cause of graft loss after renal transplantation. It has been reported to occur in 9-30%. METHODS:From March 1976 to January 2002, a total of 1400 living donor renal transplants were performed in our center. Out of 257 reported deaths among ou...

journal_title：American journal of nephrology

authors： El-Agroudy AE,Bakr MA,Shehab El-Dein AB,Ghoneim MA

更新日期：2003-05-01 00:00:00