Continuous venovenous hemodiafiltration in the treatment of acute hyperammonemia.

abstract：BACKGROUND:Aldosterone plays an important role in fibrosis. Recent studies showed that Na(+)-H(+) exchanger isoform 1 (NHE1) is involved in mineralocorticoid-induced organ fibrosis. In this study, we examined the role of NHE1 in aldosterone-induced fibronectin accumulation in rat mesangial cells and the signaling pathw...

journal_title：American journal of nephrology

authors： Zhang M,Chen J,Lai L,You L,Lin S,Hao C,Gu Y

更新日期：2010-01-01 00:00:00

abstract：:Hyperlipidemia is common in patients with glomerular proteinuria. It may contribute to atherosclerotic complications and accelerate glomerular damage. Early trials of the fibric acid derivative clofibrate led to a myositis syndrome causing many nephrologists to abandon attempts at treatment of nephrotic hyperlipidemia...

journal_title：American journal of nephrology

authors： Appel GB,Appel AS

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND/AIMS:The association between chronic kidney disease (CKD) awareness and healthy behaviors is unknown. We examined whether CKD self-recognition is associated with healthy behaviors and achieving risk-reduction targets known to decrease risk of cardiovascular morbidity and CKD progression. METHODS:CKD awarene...

journal_title：American journal of nephrology

authors： Tuot DS,Plantinga LC,Judd SE,Muntner P,Hsu CY,Warnock DG,Gutiérrez OM,Safford M,Powe NR,McClellan WM,REGARDS Investigators.

更新日期：2013-01-01 00:00:00

abstract：:The effects of cisplatin (5 mg/kg BW given intraperitoneally) on renal concentration mechanism were evaluated initially by clearance studies in rats 5-7 days after cisplatin administration and compared to normal rats. During hypotonic saline infusion, cisplatin rats showed a lower inulin clearance (0.56 +/- 0.07 vs. 1...

journal_title：American journal of nephrology

authors： Seguro AC,Shimizu MH,Kudo LH,dos Santos Rocha A

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Hyperoxaluria may result from increased endogenous production or overabsorption of dietary oxalate in the gastrointestinal tract leading to nephrolithiasis and, in some, to oxalate nephropathy and chronic kidney disease. ALLN-177 is an oral formulation of a recombinant, oxalate specific, microbial enzyme oxa...

journal_title：American journal of nephrology

authors： Langman CB,Grujic D,Pease RM,Easter L,Nezzer J,Margolin A,Brettman L

更新日期：2016-01-01 00:00:00

abstract：:Hepcidin is a key regulator of iron metabolism. In this study, we examined whether measurement of hepcidin is useful in assessing recombinant human erythropoietin (rHuEPO) responsiveness in regular hemodialysis (HD) patients in a cross-sectional fashion. We examined the association between serum prohepcidin, a prohorm...

journal_title：American journal of nephrology

authors： Kato A,Tsuji T,Luo J,Sakao Y,Yasuda H,Hishida A

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND/AIMS:We examined the correlations between renal biopsy findings in Wegener's granulomatosis and renal function at baseline and 1 year in 22 patients who presented between 1988 and 1999. METHODS:Renal histology was independently reviewed by 2 pathologists who were masked to the clinical data. The primary out...

journal_title：American journal of nephrology

authors： Haroun MK,Stone JH,Nair R,Racusen L,Hellmann DB,Eustace JA

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Apolipoprotein A1 (APOL1) gene variants occurring in people of West African descent contribute to the greater burden of kidney disease among African Americans. These variants are associated with increased risk of nondiabetic nephropathy, more rapid progression of chronic kidney disease, and shorter survival ...

journal_title：American journal of nephrology

authors： Young BA,Blacksher E,Cavanaugh KL,Freedman BI,Fullerton SM,Kopp JB,Umeukeje EM,West KM,Wilson JG,Burke W,APOL1 Stakeholders Project.

更新日期：2019-01-01 00:00:00

abstract：:The present study evaluated thyroid hormone indices of patients with acute renal failure without other systemic illnesses (n = 12), as compared to patients with critical illnesses in the presence (n = 16) and absence (n = 6) of acute renal failure. Abnormalities in the group with acute renal failure alone included dec...

journal_title：American journal of nephrology

authors： Kaptein EM,Levitan D,Feinstein EI,Nicoloff JT,Massry SG

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:It is uncertain whether kidneys from marginal donors are suitable for live kidney transplantation. In deceased donor kidneys, tubular cell senescence affects allograft function. However, the degree of cell senescence in a living donor kidney with marginal factors has not been reported. In this study, we asse...

journal_title：American journal of nephrology

authors： Sofue T,Kushida Y,Ozaki T,Moritoki M,Nishijima Y,Ohsaki H,Ueda N,Kakehi Y,Nishiyama A,Minamino T

更新日期：2018-01-01 00:00:00

abstract：:Tuberculosis associated with dialysis was studied at the Artificial Kidney Unit (AKU) in Abha, Saudi Arabia. There were 13 tuberculosis patients out of 270 patients on maintenance hemodialysis from August 1986 to July 1993, a prevalence of 4.8%. Ten (77%) were female and 3 (23%) were male, mean age of 51.23 +/- 11.62 ...

journal_title：American journal of nephrology

authors： al-Homrany M

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND/AIMS:The shortage in organ supply has required the use of expanded criteria donors (ECD) for kidney transplantation. Current pre-transplant evaluations of ECD organs are based on histological, clinical or mixed criteria. This monocentric study investigates the predictivity of Karpinski's histological score o...

journal_title：American journal of nephrology

authors： La Manna G,Comai G,Cappuccilli ML,Liviano D'Arcangelo G,Fabbrizio B,Valentini C,Carretta E,Ravaioli M,Scolari MP,Ridolfi L,Feliciangeli G,Grigioni FW,Pinna AD,Stefoni S

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Steroid therapy has become an effective option for patients with primary Sjogren's syndrome with tubulointerstitial nephritis (TIN), while the use of cytotoxic agents is still debated. Our study aimed to compare the clinical outcomes of patients treated with cyclophosphamide (CTX) combined with glucocorticoi...

journal_title：American journal of nephrology

authors： Shen Y,Xie J,Lin L,Li X,Shen P,Pan X,Ren H,Chen N

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND/AIMS:The 7-year Major Adverse Cardiovascular Events Calculator (CRCRTR-MACE) predicts cardiovascular events (CVE) in renal transplant recipients (RTR), and thrombopoietin (TPO) is a humoral inflammatory factor implicated in cardiovascular disease (CVD). The aim of the study was to determine if circulating TP...

journal_title：American journal of nephrology

authors： Mansell H,Elmoselhi H,Shoker A

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:Intradialytic hypotension is the most common complication of modern day haemodialysis (HD). Convective modalities, including haemodiafiltration (HDF) are reported to result in greater cardiovascular stability compared to standard HD, which has been suggested to be due to improved solute transport betwee...

journal_title：American journal of nephrology

authors： Kumar S,Khosravi M,Massart A,Potluri M,Davenport A

更新日期：2013-01-01 00:00:00

abstract：:A patient with advanced chronic renal failure secondary to polycystic kidney disease suffered an episode of volume contraction during which his urinary sodium concentration fell to less than 5 mEq daily. Urine sodium excretion remained at this level when later in his course he became clinically volume expanded. The pa...

journal_title：American journal of nephrology

authors： Danovitch GM,Jacobson E,Licht A

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:While the etiology of idiopathic nephrotic syndrome (idiopathic nephrotic syndrome [INS]; characterized by repeated relapses and comorbid allergic conditions) remains unknown, recent evidence suggests that dysfunction in regulatory T cells (Tregs) plays an important role in the development of INS as well as ...

journal_title：American journal of nephrology

authors： Tsuji S,Suruda C,Hashiyada M,Kimata T,Yamanouchi S,Kitao T,Kino J,Akane A,Kaneko K

更新日期：2018-01-01 00:00:00

abstract：:A patient with unilateral gross hematuria was found to have mesangial proliferation and IgM deposition on renal biopsy, consistent with the entity of primary renal hematuria. This case refutes previous assumptions that renal biopsy is normal in patients with unilateral hematuria. Glomerular lesions may be more common ...

journal_title：American journal of nephrology

authors： Tapp DC,Whitaker WR,Copley JB

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Data concerning long-term mortality predictors among large, purely diabetic hemodialysis collectives are scarce. METHODS:We used data from a multicenter, prospective, randomized trial among 1,255 hemodialysis patients with type 2 diabetes mellitus (T2DM) and its observational follow-up study. The associatio...

journal_title：American journal of nephrology

authors： Triebswetter S,Gutjahr-Lengsfeld LJ,Schmidt KR,Drechsler C,Wanner C,Krane V

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:We investigated the gender differences in the effect of ACE I/D and AGT M235T polymorphisms on the prognosis of diabetic nephropathy (DN). METHODS:A total of 525 type 2 diabetics were enrolled to participate in this prospective observational study. ACE and AGT gene polymorphisms were analyzed by polymerase ...

journal_title：American journal of nephrology

authors： Tien KJ,Hsiao JY,Hsu SC,Liang HT,Lin SR,Chen HC,Hsieh MC

更新日期：2009-01-01 00:00:00

abstract：:We carried out a prospective 2-year study on the transmission of human immunodeficiency virus (HIV) infection in a chronic dialysis unit with a high prevalence (11%) of the infection. Only 1 of 45 HIV-negative patients seroconverted, and this was related to the administration of contaminated blood. We conclude that cu...

journal_title：American journal of nephrology

authors： Perez GO,Ortiz C,De Medina M,Schiff E,Bourgoignie JJ

更新日期：1988-01-01 00:00:00

abstract：:Heavy proteinuria in patients with essential hypertension raises the question of underlying primary renal disease. While malignant hypertension may be associated with proteinuria in the nephrotic range, it is generally held that protein excretion in benign nephrosclerosis is almost invariably less than 0.5-1.0 g/24 h....

journal_title：American journal of nephrology

authors： Mujais SK,Emmanouel DS,Kasinath BS,Spargo BH

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Interest in nephrology careers is declining, possibly due to perceptions of the field and/or training aspects. Understanding practices of medical schools successfully instilling nephrology interest could inform efforts to attract leading candidates to the specialty. METHODS:The American Society of Nephrolog...

journal_title：American journal of nephrology

authors： Sozio SM,Pivert KA,Shah HH,Chakkera HA,Asmar AR,Varma MR,Morrow BD,Patel AB,Leight K,Parker MG

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Medullary sponge kidney (MSK) is characterized by malformation of the terminal collecting ducts and is associated with an increased risk of nephrolithiasis, nephrocalcinosis, urinary tract infections, renal acidification defects, and reduced bone density. It has been historically diagnosed with intravenous p...

journal_title：American journal of nephrology

authors： Koraishy FM,Ngo TT,Israel GM,Dahl NK

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Renal insufficiency is a well-described risk factor for perioperative morbidity and shortened survival after major vascular procedures. Due to the potential inaccuracy of serum creatinine levels alone in measuring kidney function, our aim was to determine whether estimated creatinine clearance more consisten...

journal_title：American journal of nephrology

authors： Maithel SK,Pomposelli FB,Williams M,Sheahan MG,Scovell SD,Campbell DR,LoGerfo FW,Hamdan AD

更新日期：2006-01-01 00:00:00

abstract：:Nutrition has been shown to predict clinical outcome in continuous ambulatory peritoneal dialysis (CAPD) patients. However, despite the positive relationship between KT/V (urea) and the normalised protein catabolic rate, the ability of urea kinetic modelling to predict clinical outcome or nutrition remains inconclusiv...

journal_title：American journal of nephrology

authors： Harty J,Boulton H,Heelis N,Uttley L,Venning M,Gokal R

更新日期：1993-01-01 00:00:00

abstract：:Five patients with the clinical patterns of Bartter's syndrome underwent a series of clearance studies in order to characterize the underlying tubule defect. Free water generation during maximal water diuresis (CH2O), expressed as percentage of the distal delivery (CH2O + CCl), was lower in the patients (72.5 +/- 3.2%...

journal_title：American journal of nephrology

authors： Colussi G,Rombolà G,Verde G,Airaghi C,Loli P,Minetti L

更新日期：1992-01-01 00:00:00

abstract：:Bacterial endocarditis, particularly involving the left side, has been shown to occur in patients in regular hemodialysis. We report a case of right-sided endocarditis characterized by a very torpid evolution. Although the diagnosis was suspected early in the course, confirmation was obtained 2 months after the onset....

journal_title：American journal of nephrology

authors： Ferrer C,Jakob E,Pastorino G,Juncos LI

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND/AIMS:Previous studies have shown that L-type Ca2+ channel (LCC) blockers prevent the afferent arteriolar (AA) vasoconstriction elicited by angiotensin II (Ang II), but do not influence its vasoconstrictor effect on efferent arterioles (EA). The present study tested the hypothesis that Ang II-mediated constri...

journal_title：American journal of nephrology

authors： Feng MG,Navar LG

更新日期：2004-11-01 00:00:00

abstract：:Alcaligenes xylosoxidans is an uncommon cause of peritonitis in patients on maintenance continuous ambulatory peritoneal dialysis (CAPD). Peritonitis caused by A. xylosoxidans usually carries a poor prognosis because of the pathogen's virulence and its universal resistance to most antimicrobial agents. Even after earl...

journal_title：American journal of nephrology

authors： Tang S,Cheng CC,Tse KC,Li FK,Choy BY,Chan TM,Lai KN

更新日期：2001-11-01 00:00:00