Increased low-density lipoprotein S-homocysteinylation in chronic kidney disease.

abstract：BACKGROUND:Increased mortality and morbidity are reported in association with high ultrafiltration rate (UFR) and with long dialysis recovery time (DRT). We studied the association between UFR and DRT. METHODS:This is a cross-sectional, observational study was conducted. Patients on thrice-weekly hemodialysis (HD) wit...

journal_title：American journal of nephrology

authors： Hussein WF,Arramreddy R,Sun SJ,Reiterman M,Schiller B

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Serum protein profiling patterns can reflect the pathological state of a patient and therefore may be useful for clinical diagnostics. Here, we present results from a pilot study of proteomic expression patterns in hemodialysis patients designed to evaluate the range of serum proteomic alterations in this po...

journal_title：American journal of nephrology

authors： Langlois RG,Trebes JE,Dalmasso EA,Ying Y,Davies RW,Curzi MP,Colston BW Jr,Turteltaub KW,Perkins J,Chromy BA,Choi MW,Murphy GA,Fitch JP,McCutchen-Maloney SL

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Tacrolimus is mainly metabolized by cytochrome P450 3A5 (CYP3A5), which is expressed in the liver. However, CYP3A5 is also expressed in the kidney tissue and may contribute to local tacrolimus clearance in the kidney allograft. We aimed to evaluate the association between the allograft CYP3A5 genotype and tr...

journal_title：American journal of nephrology

authors： Udomkarnjananun S,Townamchai N,Chariyavilaskul P,Iampenkhae K,Pongpirul K,Sirichindakul B,Panumatrassamee K,Vanichanan J,Avihingsanon Y,Eiam-Ong S,Praditpornsilpa K

更新日期：2018-01-01 00:00:00

abstract：:Obese Zucker rats spontaneously develop lipoprotein abnormalities, proteinuria, mesangial expansion and glomerulosclerosis. Previous studies have implicated these lipoprotein abnormalities in the pathogenesis of the progressive renal injury which these rats develop. The present study was designed to examine the chrono...

journal_title：American journal of nephrology

authors： Kamanna VS,Kirschenbaum MA

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Despite the significant morbidity and mortality attributable to cardiovascular disease (CVD), risk stratification remains an important challenge in the chronic kidney disease (CKD) population. We examined the discriminative ability of noninvasive measures of atherosclerosis, including carotid intima-media th...

journal_title：American journal of nephrology

authors： Adeseun GA,Xie D,Wang X,Joffe MM,Mohler ER 3rd,Townsend RR,Budoff M,Rosas SE

更新日期：2012-01-01 00:00:00

abstract：:Fifty-four patients with noninsulin-dependent diabetes mellitus, who had established nephropathy, were examined to evaluate the risk factors for the progression of diabetic nephropathy. Time-averaged values of blood pressure, serum total cholesterol and fasting plasma glucose concentrations, and the degree of proteinu...

journal_title：American journal of nephrology

authors： Yokota C,Kimura G,Inenaga T,Kawano Y,Matsuoka H,Omae T

更新日期：1995-01-01 00:00:00

abstract：PURPOSE:To explore the association between CYP3A4 and CYP3A5 gene polymorphisms and blood pressure response to amlodipine among participants from the African-American Study of Kidney Disease and Hypertension Trial randomized to amlodipine (n = 164). METHODS:Cox proportional hazards models were used to determine the ri...

journal_title：American journal of nephrology

authors： Bhatnagar V,Garcia EP,O'Connor DT,Brophy VH,Alcaraz J,Richard E,Bakris GL,Middleton JP,Norris KC,Wright J,Hiremath L,Contreras G,Appel LJ,Lipkowitz MS,AASK Study Investigators.

更新日期：2010-01-01 00:00:00

abstract：:A comparative clinicopathological study was retrospectively performed in 61 children and 51 adults with IgA nephropathy. Hematuria and/or proteinuria as a chance finding was the most common initial clinical sign, being observed in 82.0% of the children and in 52.9% of the adults. At renal biopsy, hypertension and seve...

journal_title：American journal of nephrology

authors： Okada K,Funai M,Kawakami K,Kagami S,Yano I,Kuroda Y

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:To promote understanding of immunoglobulin A nephropathy (IgAN) pathophysiology, we tried to elucidate glomerular protein profiles in IgAN, using microsieving that we established recently to isolate glomeruli from renal biopsy samples and proteomic approaches. METHODS:Glomeruli were isolated from renal biop...

journal_title：American journal of nephrology

authors： Kojima S,Koitabashi K,Iizuka N,Okamoto K,Arito M,Sato T,Kurokawa MS,Suematsu N,Shibagaki Y,Yasuda T,Kimura K,Kato T

更新日期：2014-01-01 00:00:00

abstract：:We carried out a prospective 2-year study on the transmission of human immunodeficiency virus (HIV) infection in a chronic dialysis unit with a high prevalence (11%) of the infection. Only 1 of 45 HIV-negative patients seroconverted, and this was related to the administration of contaminated blood. We conclude that cu...

journal_title：American journal of nephrology

authors： Perez GO,Ortiz C,De Medina M,Schiff E,Bourgoignie JJ

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND/AIMS:Few published data describe survival rates for pediatric end-stage renal disease (ESRD) patients. We aimed to describe one-year mortality rates for US pediatric ESRD patients over a 15-year period. METHODS:In this retrospective cohort study, we used the US Renal Data System database to identify period-...

journal_title：American journal of nephrology

authors： Chavers BM,Molony JT,Solid CA,Rheault MN,Collins AJ

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Various medications are cleared by the kidneys, therefore patients with impaired renal function, especially dialysis patients are at risk for adverse drug events (ADEs). There are limited studies on ADEs in maintenance dialysis patients. METHODS:We utilized a nationally representative database, the Nationwi...

journal_title：American journal of nephrology

authors： Chan L,Saha A,Poojary P,Chauhan K,Naik N,Coca S,Garimella PS,Nadkarni GN

更新日期：2018-01-01 00:00:00

abstract：UNLABELLED:Although it is anticipated that most patients with renal insufficiency will progress towards end-stage renal disease (ESRD) there have been few population-based studies to validate this assumption. We examined serial creatinines from 3,874 anonymous patients at an urban VA medical center who had a baseline c...

journal_title：American journal of nephrology

authors： Fink JC,Salmanullah M,Blahut SA,Weir MR,Sawyer R,Henrich WL,Hise MK

更新日期：2001-09-01 00:00:00

abstract：AIMS:This study investigated the protective effect of the angiotensin-converting enzyme inhibitor, enalapril, and the vitamin D analog, paricalcitol, alone or in combination, on cardiac oxidative stress in uremic rats. METHODS:Rats were made uremic by 5/6 nephrectomy and treated for 4 months as follows: (1) uremic + v...

journal_title：American journal of nephrology

authors： Husain K,Ferder L,Mizobuchi M,Finch J,Slatopolsky E

更新日期：2009-01-01 00:00:00

abstract：:We have compared the renal effects of ioxitalamate, ioxaglate, and iopamidol in patients with chronic renal failure. Sixty consecutive patients with an estimated creatinine clearance (ECRCl) less than 60 ml/min were randomly assigned to receive either ioxitalamate, iopamidol, or ioxaglate. All patients received 500 cm...

journal_title：American journal of nephrology

authors： Deray G,Bellin MF,Boulechfar H,Baumelou B,Koskas F,Baumelou A,Grellet J,Jacobs C

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Almost 20 million people in the US have chronic kidney disease (CKD). Cardiovascular disease and arterial wall abnormalities are common in this population. Because angiotensin II may have adverse effects on the arterial wall, we hypothesized that an angiotensin receptor blocker (ARB) would improve arterial c...

journal_title：American journal of nephrology

authors： Garg JP,Ellis R,Elliott WJ,Hasabou N,Chua D,Chertow GM,Bakris GL

更新日期：2005-07-01 00:00:00

abstract：:The terminal complement-inhibitor eculizumab has dramatically changed the management of patients with atypical hemolytic uremic syndrome (aHUS), and has also shown promise for treating certain forms of secondary HUS (sHUS), including that caused by drugs and solid-organ/hematopoietic stem cell transplant. While effect...

journal_title：American journal of nephrology

authors： Olson SR,Lu E,Sulpizio E,Shatzel JJ,Rueda JF,DeLoughery TG

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Treatment of metabolic acidosis to target the higher serum bicarbonate level than guideline recommendation may downregulate muscle protein degradation and improve renal function among chronic kidney disease (CKD) patients. We conducted a study to test the effects of increased serum bicarbonate level on muscl...

journal_title：American journal of nephrology

authors： Kittiskulnam P,Srijaruneruang S,Chulakadabba A,Thokanit NS,Praditpornsilpa K,Tungsanga K,Eiam-Ong S

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Patients with chronic kidney disease (CKD) show increased cardiovascular morbidity. We hypothesized that vascular properties which can be routinely evaluated noninvasively are related to different stages of CKD and their clinical and biochemical characteristics. METHODS:Arterial vascular properties were qua...

journal_title：American journal of nephrology

authors： Tetzner F,Scholze A,Wittstock A,Zidek W,Tepel M

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Vascular calcification is seen in most patients on dialysis and is strongly associated with cardiovascular mortality. Vascular calcification is promoted by phosphate, which generally reaches higher levels in hemodialysis than in peritoneal dialysis. However, whether vascular calcification develops less in pe...

journal_title：American journal of nephrology

authors： Jansz TT,van Reekum FE,Özyilmaz A,de Jong PA,Boereboom FTJ,Hoekstra T,Verhaar MC,van Jaarsveld BC

更新日期：2018-01-01 00:00:00

abstract：:We report on a Mycobacterium marinum infection in a diabetic woman 8 years after undergoing a combined pancreas-kidney transplantation. This is, to our knowledge, the first case report on an isolated skin infection with atypical mycobacteria after simultaneous pancreas-kidney transplantation. A genetic probe categoriz...

journal_title：American journal of nephrology

authors： Schmekal B,Janko O,Zazgornik J,Schinko H,Bogner S,Syre G,Biesenbach G

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND/AIMS:HFE protein controls iron absorption and cycling, and HFE mutations influence iron status. The aim was to evaluate the effect of the HFE genotype on the need for iron and erythropoietin in Italian hemodialysis patients. METHODS:Ninety-six prevalent patients were evaluated at the time of enrolment and p...

journal_title：American journal of nephrology

authors： Valenti L,Valenti G,Como G,Santorelli G,Dongiovanni P,Rametta R,Fracanzani AL,Tavazzi D,Messa PG,Fargion S

更新日期：2008-01-01 00:00:00

abstract：:Percutaneous angioplasty was attempted in 5 patients with acute renal failure due to occlusion of the artery to a solitary functioning kidney. Angioplasty was technically successful in all patients. Renal function was completely restored in 3 and renal perfusion improved in 1 patient. In the fifth patient, renal funct...

journal_title：American journal of nephrology

authors： Kadir S,Watson A,Burrow C

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Pulmonary arterial hypertension (PAH) may lead to right heart failure and subsequently alter glomerular filtration rates (GFR). Chronic kidney disease (CKD, GFR <60 mL/min/1.73 m2) may also adversely affect PAH prognosis. This study aimed to assess how right heart hemodynamics was associated with reduced est...

journal_title：American journal of nephrology

authors： Bitker L,Sens F,Payet C,Turquier S,Duclos A,Cottin V,Juillard L

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND/AIMS:The shortage in organ supply has required the use of expanded criteria donors (ECD) for kidney transplantation. Current pre-transplant evaluations of ECD organs are based on histological, clinical or mixed criteria. This monocentric study investigates the predictivity of Karpinski's histological score o...

journal_title：American journal of nephrology

authors： La Manna G,Comai G,Cappuccilli ML,Liviano D'Arcangelo G,Fabbrizio B,Valentini C,Carretta E,Ravaioli M,Scolari MP,Ridolfi L,Feliciangeli G,Grigioni FW,Pinna AD,Stefoni S

更新日期：2013-01-01 00:00:00

abstract：:Administration of a single dose of 1,25-OH(2)D(3) can lower PTH levels for up to 4 days in chronic hemodialysis patients. Our purpose was to verify the effects of the same weekly dose of calcitriol per os given in one, two or three administrations, to patients on dialysis with secondary hyperparathyroidism. Thirty pat...

journal_title：American journal of nephrology

authors： Manni M,Calabria S,Dinnella A,D'Anello E,Mantella D,Sardella D,Sturniolo A,Splendiani G,Coen G

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Telomere attrition is a novel risk factor for cardiovascular disease. Studies of telomere length in relation to kidney function are limited. We explored the association of kidney function with telomere length and telomere shortening. METHODS:The Heart and Soul Study is a longitudinal study of patients with ...

journal_title：American journal of nephrology

authors： Bansal N,Whooley MA,Regan M,McCulloch CE,Ix JH,Epel E,Blackburn E,Lin J,Hsu CY

更新日期：2012-01-01 00:00:00

abstract：:Historically, stroke, heart failure and renal insufficiency were seen as the major complications of untreated hypertension. More recently, it has become evident that coronary heart disease is probably the most common outcome of this condition. Unlike the other complications of hypertension, coronary events have not be...

journal_title：American journal of nephrology

authors： Weber MA

更新日期：1996-01-01 00:00:00

abstract：:A patient with progressive systemic sclerosis (PSS) involving skin, digit, esophagus, and lung developed the nephrotic syndrome and rapidly progressive renal insufficiency. Renal pathology revealed capillary collapse, cellular crescents, arteriolar hyaline deposition, and mesangial proliferation. On immunofluorescence...

journal_title：American journal of nephrology

authors： Eiser AR,Zilversmit R,Neff MS,Grishman E,Slifkin RF

更新日期：1986-01-01 00:00:00

abstract：:A patient with renal failure due to myeloma kidney and coincident digitalis intoxication due to prescribed daily digoxin administration was treated with digoxin-specific antibody fragments and plasmapheresis. Rapid response to therapy was noted, removal of digoxin-antidigoxin antibody complexes was confirmed, and prev...

journal_title：American journal of nephrology

authors： Rabetoy GM,Price CA,Findlay JW,Sailstad JM

更新日期：1990-01-01 00:00:00