Serum protein profile alterations in hemodialysis patients.

abstract：BACKGROUND/AIMS:Living donor nephrectomy can be associated with increases in blood pressure several years following the procedure, but the best method to assess blood pressure during the living donor evaluation process is unclear. METHODS:Living kidney donors underwent casual clinic and ambulatory blood pressure monit...

journal_title：American journal of nephrology

authors： DeLoach SS,Meyers KE,Townsend RR

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Kidney failure is believed to have a negative impact on cognitive function, and cognitive impairment is common among maintenance hemodialysis (HD) patients. Previous studies have shown a beneficial effect of kidney transplantation in certain cognitive tests but not across all cognitive domains assessed. But,...

journal_title：American journal of nephrology

authors： Radić J,Ljutić D,Radić M,Kovačić V,Dodig-Ćurković K,Šain M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Transplant glomerulopathy (TG) represents a major cause of long-term allograft failure and is the leading cause of overall post-transplant proteinuria. The extent to which histopathologic features predicts prognostication is uncertain. METHODS:A single-center retrospective cohort with biopsy-proven TG was i...

journal_title：American journal of nephrology

authors： Li X,Chen J,Cheng D,Wang W,Xie K,Zhang M,Xu F,Wen J,Tang Z

更新日期：2019-01-01 00:00:00

abstract：:Two patients are reported who presented within the first 3 months posttransplantation with acute bone pain where serial magnetic resonance imaging (MRI) allowed differentiation between bone edema, which resolved spontaneously, and avascular necrosis (AVN) requiring core decompression. Case 1 had ill-defined images con...

journal_title：American journal of nephrology

authors： Pilmore H,Walker R,McMillan B,Paranjpe D,Berkeley B

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND/AIMS:Studies have shown that kidney injury molecule-1 (KIM-1) is upregulated in damaged renal proximal tubules. In this study, we examined KIM-1 expression in glomerular epithelial cells in diabetic glomerulopathy. METHODS:Renal histology, immunostaining and Western blot for protein level, and real-time PCR...

journal_title：American journal of nephrology

authors： Zhao X,Zhang Y,Li L,Mann D,Imig JD,Emmett N,Gibbons G,Jin LM

更新日期：2011-01-01 00:00:00

abstract：:We report a 29-year-old female with recurrent focal glomerulosclerosis (FGS) presenting as heavy proteinuria immediately following renal transplantation. From day 13 after transplantation, daily plasma exchange was performed 6 times. Proteinuria decreased from 13 to 0.2 g/day after plasma exchange and remained to be l...

journal_title：American journal of nephrology

authors： Li PK,Lai FM,Leung CB,Lui SF,Wang A,Lai KN

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND/AIMS:Upregulation of transforming growth factor beta (TGF-beta)/Smad signaling has been implicated in the primary pathogenesis of renal fibrosis. The ubiquitin-proteasome pathway has an important influence on TGF-beta signaling through regulating Smad degradation. As E3 ubiquitin ligases, both Arkadia and Sm...

journal_title：American journal of nephrology

authors： Liu FY,Li XZ,Peng YM,Liu H,Liu YH

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Despite a previous study showing that PINCH-1 exerts an important role in regulating TGF-β1-mediated mesenchymal transition through its interaction with integrin-linked kinase, relatively little is known about the role of PINCH in the obstructive nephropathy. METHODS:To construct a rat model of renal inters...

journal_title：American journal of nephrology

authors： Jia L,Li X,Gu Y,Cui W

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Clinical indicators for accurately distinguishing diabetic nephropathy (DN) from non-diabetic renal disease in type 2 diabetes (T2D) are lacking. This study aimed to develop and validate a nomogram for predicting DN in T2D patients with kidney disease. METHODS:A total of 302 consecutive patients with T2D wh...

journal_title：American journal of nephrology

authors： Jiang S,Fang J,Yu T,Liu L,Zou G,Gao H,Zhuo L,Li W

更新日期：2020-01-01 00:00:00

abstract：:45 bone biopsies from patients with chronic uremia were reviewed to define which noninvasive investigations were of value in predicting the histological diagnosis and to quantify the spectrum of uremic bone disease at a center that has consistently used an aluminum-free dialysis bath. 17 biopsies were taken postmortem...

journal_title：American journal of nephrology

authors： Heaf JG,Joffe P,Pødenphant J,Andersen JR

更新日期：1987-01-01 00:00:00

abstract：:Whole plasma from 6 normolipidemic chronic renal failure (CRF) patients undergoing hemodialysis treatment was passed through the anti-apolipoprotein (Apo) AI immunosorbent column connected to the anti-Apo B immunoaffinity column. Apo AI and B containing particles were analyzed for lipid and Apo contents. The results w...

journal_title：American journal of nephrology

authors： Kandoussi AM,Hugue V,Parra HJ,Dracon M,Fruchart JC,Tacquet A,Cachera C

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Detection of chronic kidney disease (CKD) with urine albumin-to-creatinine ratio (UACR) among patients with hypertension (HTN) provides an opportunity for early treatment, potentially mitigating risk of CKD progression and cardiovascular complications. Differences in UACR testing patterns among racial/ethnic...

journal_title：American journal of nephrology

authors： Lee J,Chu C,Guzman D,Fontil V,Velasquez A,Powe NR,Tuot DS

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:Intradialytic hypotension is the most common complication of modern day haemodialysis (HD). Convective modalities, including haemodiafiltration (HDF) are reported to result in greater cardiovascular stability compared to standard HD, which has been suggested to be due to improved solute transport betwee...

journal_title：American journal of nephrology

authors： Kumar S,Khosravi M,Massart A,Potluri M,Davenport A

更新日期：2013-01-01 00:00:00

abstract：:We carried out a prospective 2-year study on the transmission of human immunodeficiency virus (HIV) infection in a chronic dialysis unit with a high prevalence (11%) of the infection. Only 1 of 45 HIV-negative patients seroconverted, and this was related to the administration of contaminated blood. We conclude that cu...

journal_title：American journal of nephrology

authors： Perez GO,Ortiz C,De Medina M,Schiff E,Bourgoignie JJ

更新日期：1988-01-01 00:00:00

abstract：:To define the incidence of non-A, non-B (NANB) hepatitis and evaluate possible risk factors, we reviewed records of 163 patients on chronic dialysis during a 3-year period. 23 cases of NANB hepatitis occurred, 13 (27%) in 49 center dialysis, 8 (10%) in 77 home hemodialysis (p less than 0.02) and 2 (5%) in 37 peritonea...

journal_title：American journal of nephrology

authors： Seaworth BJ,Garrett LE,Stead WW,Hamilton JD

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND/AIMS:We examined the correlations between renal biopsy findings in Wegener's granulomatosis and renal function at baseline and 1 year in 22 patients who presented between 1988 and 1999. METHODS:Renal histology was independently reviewed by 2 pathologists who were masked to the clinical data. The primary out...

journal_title：American journal of nephrology

authors： Haroun MK,Stone JH,Nair R,Racusen L,Hellmann DB,Eustace JA

更新日期：2002-09-01 00:00:00

abstract：:Bardoxolone methyl has been reported to cause detrimental cardiovascular events in the terminated BEACON Phase III human clinical trial via modulation of the renal endothelin pathway. However, the effects of bardoxolone methyl administration on the endothelin pathway in the heart are unknown. Our purpose in this persp...

journal_title：American journal of nephrology

authors： Camer D,Huang XF

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:The elderly are the fastest growing subpopulation with end-stage renal disease. The goal of our study was to define characteristics of elderly patients who were considered ineligible for transplantation compared to those who were listed. METHODS:984 patients were referred for evaluation during a 2-year...

journal_title：American journal of nephrology

authors： Lenihan CR,Hurley MP,Tan JC

更新日期：2013-01-01 00:00:00

abstract：:Acute hyperammonemia is an emergent cause of central nervous system dysfunction for which renal replacement therapy is advocated. We report the successful use of continuous venovenous hemodiafiltration in this metabolic emergency, and report the calculated ammonia clearances for both continuous venovenous hemofiltrati...

journal_title：American journal of nephrology

authors： Braun MC,Welch TR

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Aldosterone plays an important role in fibrosis. Recent studies showed that Na(+)-H(+) exchanger isoform 1 (NHE1) is involved in mineralocorticoid-induced organ fibrosis. In this study, we examined the role of NHE1 in aldosterone-induced fibronectin accumulation in rat mesangial cells and the signaling pathw...

journal_title：American journal of nephrology

authors： Zhang M,Chen J,Lai L,You L,Lin S,Hao C,Gu Y

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND/AIMS:Although the effect of exercise on health is well established, nephrologists seldom consider physical activity in the treatment of chronic kidney disease (CKD) or CKD in the presence of diabetes mellitus (DM/CKD). The aim of the present study was to analyze the benefits of leisure-time physical activity...

journal_title：American journal of nephrology

authors： Wang IK,Tsai MK,Liang CC,Yen TH,Huang CC,Wen SF,Wen CP

更新日期：2013-01-01 00:00:00

abstract：:Bicarbonate dialysate is claimed to be superior to acetate for both chronic and acute hemodialysis. We compared acetate and bicarbonate dialysates in 30 acute renal failure patients during 120 dialyses. 4 patients were diabetic and 2 had liver failure. Patients were dialyzed alternating acetate and bicarbonate dialysa...

journal_title：American journal of nephrology

authors： Borges HF,Fryd DS,Rosa AA,Kjellstrand CM

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Three million people in the United States are estimated to have chronic kidney disease (CKD). Management of these CKD patients in the outpatient primary care clinic setting has not been well studied. HYPOTHESIS:Primary care management of CKD can be assessed and opportunities for improvement can be identifie...

journal_title：American journal of nephrology

authors： Israni A,Korzelius C,Townsend R,Mesler D

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Almost 20 million people in the US have chronic kidney disease (CKD). Cardiovascular disease and arterial wall abnormalities are common in this population. Because angiotensin II may have adverse effects on the arterial wall, we hypothesized that an angiotensin receptor blocker (ARB) would improve arterial c...

journal_title：American journal of nephrology

authors： Garg JP,Ellis R,Elliott WJ,Hasabou N,Chua D,Chertow GM,Bakris GL

更新日期：2005-07-01 00:00:00

abstract：:Forty-eight chronic hemodialysis patients were divided comparably into two groups (24 patients in each). Two micrograms of 1 alpha(OH)D3 was administered to one group for 3 months and its placebo to the other group. In the 1 alpha(OH)D3-treated group, serum total calcium increased from 7.82 +/- 0.11 (mean +/- SEM) to ...

journal_title：American journal of nephrology

authors： Shimamatsu K,Onoyama K,Fujimi S,Iseki K,Fujishima M

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND/AIMS:Previous studies have shown that L-type Ca2+ channel (LCC) blockers prevent the afferent arteriolar (AA) vasoconstriction elicited by angiotensin II (Ang II), but do not influence its vasoconstrictor effect on efferent arterioles (EA). The present study tested the hypothesis that Ang II-mediated constri...

journal_title：American journal of nephrology

authors： Feng MG,Navar LG

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Pulmonary arterial hypertension (PAH) may lead to right heart failure and subsequently alter glomerular filtration rates (GFR). Chronic kidney disease (CKD, GFR <60 mL/min/1.73 m2) may also adversely affect PAH prognosis. This study aimed to assess how right heart hemodynamics was associated with reduced est...

journal_title：American journal of nephrology

authors： Bitker L,Sens F,Payet C,Turquier S,Duclos A,Cottin V,Juillard L

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Adherence is paramount in treating hypertension; however, no gold standard method is available for non-adherence screening, delineating high-risk patients. An International Classification of Diseases 9th Edition non-adherence diagnostic code (V15.81) has been available for decades; but, its utility is poorly...

journal_title：American journal of nephrology

authors： Gosmanova EO,Molnar MZ,Alrifai A,Lu JL,Streja E,Cushman WC,Kalantar-Zadeh K,Kovesdy CP

更新日期：2015-01-01 00:00:00

abstract：AIMS:This study investigated the protective effect of the angiotensin-converting enzyme inhibitor, enalapril, and the vitamin D analog, paricalcitol, alone or in combination, on cardiac oxidative stress in uremic rats. METHODS:Rats were made uremic by 5/6 nephrectomy and treated for 4 months as follows: (1) uremic + v...

journal_title：American journal of nephrology

authors： Husain K,Ferder L,Mizobuchi M,Finch J,Slatopolsky E

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Vitamin D deficiency, sympathetic activation and endothelial dysfunction are associated with increased cardiovascular risk in patients with chronic kidney disease (CKD). Studies have so far failed to establish the role of vitamin D and vitamin D receptor activator (VDRA) treatment in moderate CKD. This trial...

journal_title：American journal of nephrology

authors： Lundwall K,Jörneskog G,Jacobson SH,Spaak J

更新日期：2015-01-01 00:00:00