Hypotension during acetate and bicarbonate dialysis in patients with acute renal failure.

Abstract:

:Bicarbonate dialysate is claimed to be superior to acetate for both chronic and acute hemodialysis. We compared acetate and bicarbonate dialysates in 30 acute renal failure patients during 120 dialyses. 4 patients were diabetic and 2 had liver failure. Patients were dialyzed alternating acetate and bicarbonate dialysate in a double-blind cross-over manner; each patient was his own control. BUN, creatinine, Na+, K+, osmolality, delta osmolality, % ultrafiltration, arterial blood gases, pre, post and lowest dialysis mean arterial blood pressure, dialysis with hypotensive episodes and symptoms of hypotension were recorded. The measurements obtained for each patient during dialyses with acetate and bicarbonate were compared. There was no difference in predialysis chemistries, osmolality or osmolality fall, no change in mean arterial blood pressure or hypotensive episodes and symptoms and ultrafiltration. PCO2 and pH were slightly lower for the acetate group at the 2nd h but not at the end of dialysis. 4 patients had serum acetate determinations, all metabolized acetate normally. These findings contradict recent suggestions that severely ill patients should not be dialyzed against acetate. Since acetate is technically much easier to use and has no clinical drawbacks, it does not need to be replaced with bicarbonate in acute patients. Other factors must be more important than acetate in generating hypotension during acute dialysis.

journal_name

Am J Nephrol

authors

Borges HF,Fryd DS,Rosa AA,Kjellstrand CM

doi

10.1159/000166484

subject

Has Abstract

pub_date

1981-01-01 00:00:00

pages

24-30

issue

1

eissn

0250-8095

issn

1421-9670

journal_volume

1

pub_type

临床试验,杂志文章
  • Effect of proteinuria on renal interstitium: effect of products of nitrogen metabolism.

    abstract::Tubulointerstitial disease is an invariant finding in proteinuric renal disease regardless of the underlying disease or the compartment in which the disease originates. Such histologic changes are functionally significant in that scores of such injury rather than glomerular histologic injury correlate with decrements ...

    journal_title:American journal of nephrology

    pub_type: 杂志文章,评审

    doi:10.1159/000168652

    authors: Agarwal A,Nath KA

    更新日期:1993-01-01 00:00:00

  • Living donor kidney donation: another form of white coat effect.

    abstract:BACKGROUND/AIMS:Living donor nephrectomy can be associated with increases in blood pressure several years following the procedure, but the best method to assess blood pressure during the living donor evaluation process is unclear. METHODS:Living kidney donors underwent casual clinic and ambulatory blood pressure monit...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000335070

    authors: DeLoach SS,Meyers KE,Townsend RR

    更新日期:2012-01-01 00:00:00

  • Clinical utility of malnutrition-inflammation score in maintenance hemodialysis patients: focus on identifying the best cut-off point.

    abstract:BACKGROUND:Malnutrition-inflammation score (MIS) is a comprehensive and quantitative system to assess malnutrition-inflammation complex syndrome, and a strong correlation between MIS and morbidity/mortality in maintenance hemodialysis (MHD) patients had been demonstrated. However, there is no cut-off value of MIS to ca...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000137684

    authors: Ho LC,Wang HH,Peng YS,Chiang CK,Huang JW,Hung KY,Hu FC,Wu KD

    更新日期:2008-01-01 00:00:00

  • Persistent elevation of C-reactive protein may predict cardiac hypertrophy and dysfunction in patients maintained on hemodialysis.

    abstract:BACKGROUND:C-reactive protein (CRP), which reflects chronic inflammation, is a strong predictor of cardiovascular mortality in hemodialysis patients. We investigated whether persistent elevation of CRP is associated with cardiac function and morphology in patients maintained on hemodialysis. METHODS:Predialysis high-s...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000085585

    authors: Kim BS,Jeon DS,Shin MJ,Kim YO,Song HC,Lee SH,Kim SY,Choi EJ,Chang YS,Bang BK

    更新日期:2005-05-01 00:00:00

  • Impaired phagocytosis in dialysis patients: studies on mechanisms.

    abstract::Dialysis patients have increased susceptibility to infection and this is, in part, due to impaired phagocytic and bactericidal activities of polymorphonuclear leukocytes (PMNL). The mechanisms responsible for the reduced phagocytosis are not known. Dialysis patients have elevated blood levels of parathyroid hormone (P...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000168284

    authors: Alexiewicz JM,Smogorzewski M,Fadda GZ,Massry SG

    更新日期:1991-01-01 00:00:00

  • Incidence and risk factors for acute kidney injury in HIV Infection.

    abstract:BACKGROUND/AIMS:Although HIV-infected persons are at higher risk for acute kidney injury (AKI) during hospitalization compared with their uninfected counterparts, risk factors for AKI are not well-defined. We aimed to describe the evolving incidence of AKI among HIV-infected individuals and to identify important AKI ri...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000337151

    authors: Li Y,Shlipak MG,Grunfeld C,Choi AI

    更新日期:2012-01-01 00:00:00

  • Left ventricular hypertrophy in hypertensive patients with autosomal dominant polycystic kidney disease: influence of blood pressure and humoral and neurohormonal factors.

    abstract::Left ventricular hypertrophy (LVH) is a common finding in hypertensive autosomal dominant polycystic kidney disease (ADPKD) patients. There are few studies on the influence of blood pressure (BP) and nonhemodynamic factors on LVH in these patients. The aim of this study was to evaluate the relationship between BP, hum...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000013583

    authors: Martinez-Vea A,Valero FA,Bardaji A,Gutierrez C,Broch M,Garcia C,Richart C,Oliver JA

    更新日期:2000-05-01 00:00:00

  • Increasing Medical Student Interest in Nephrology.

    abstract:BACKGROUND:Interest in nephrology careers is declining, possibly due to perceptions of the field and/or training aspects. Understanding practices of medical schools successfully instilling nephrology interest could inform efforts to attract leading candidates to the specialty. METHODS:The American Society of Nephrolog...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000501058

    authors: Sozio SM,Pivert KA,Shah HH,Chakkera HA,Asmar AR,Varma MR,Morrow BD,Patel AB,Leight K,Parker MG

    更新日期:2019-01-01 00:00:00

  • Intradialytic Activities and Health-Related Quality of Life Among Hemodialysis Patients.

    abstract:BACKGROUND:Health-related quality of life (HRQOL) reflects a patient's perceived disease burden, treatment effectiveness, and health status. Given the time burden and physiologic effects of hemodialysis, patients who spend dialysis time (9-15 h/week) physically or intellectually engaged may have better HRQOL. We charac...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000492623

    authors: Warsame F,Ying H,Haugen CE,Thomas AG,Crews DC,Shafi T,Jaar B,Chu NM,Segev DL,McAdams-DeMarco MA

    更新日期:2018-01-01 00:00:00

  • Is hepcidin a link between anemia, inflammation and liver function in hemodialyzed patients?

    abstract:BACKGROUND:Hepcidin synthesis in hepatocytes is modulated in response to anemia, hypoxia or inflammation. A cross-sectional study was performed to assess hepcidin correlations with markers of iron status, erythropoietin therapy and markers of inflammation in hemodialyzed patients and in the healthy volunteers. METHODS...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000089266

    authors: Małyszko J,Małyszko JS,Hryszko T,Pawlak K,Mysliwiec M

    更新日期:2005-11-01 00:00:00

  • Imaging uremic red blood cells with the atomic force microscope.

    abstract::Ultramorphological images and details of an uremic echinocyte are shown. The images confirm the existence of uremic echinocytes and demonstrate that atomic force microscopy can provide high-resolution images of cell surfaces. ...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000168714

    authors: Zachée P,Boogaerts M,Snauwaert J,Hellemans L

    更新日期:1994-01-01 00:00:00

  • Skin tuberculosis with atypical mycobacteria 8 years after combined pancreas-kidney transplantation.

    abstract::We report on a Mycobacterium marinum infection in a diabetic woman 8 years after undergoing a combined pancreas-kidney transplantation. This is, to our knowledge, the first case report on an isolated skin infection with atypical mycobacteria after simultaneous pancreas-kidney transplantation. A genetic probe categoriz...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000065271

    authors: Schmekal B,Janko O,Zazgornik J,Schinko H,Bogner S,Syre G,Biesenbach G

    更新日期:2002-09-01 00:00:00

  • Seasonal blood pressure and body weight variation in patients on chronic hemodialysis.

    abstract:AIM:The relation of ambient temperature (AMT) and relative humidity to systolic blood pressure (SBP), diastolic blood pressure (DBP), body weight (BW), and body weight gain between dialysis sessions (DeltaBW) was examined in hemodialysis patients by Fourier analysis. METHODS AND RESULTS:The authors recruited 144 dialy...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000013538

    authors: Tozawa M,Iseki K,Iseki C,Morita O,Yoshi S,Fukiyama K

    更新日期:1999-01-01 00:00:00

  • Treatment of Henoch-Schönlein Purpura glomerulonephritis in children with high-dose corticosteroids plus oral cyclophosphamide.

    abstract:BACKGROUND:Henoch-Schönlein Purpura (HSP) is a common childhood vasculitis with manifestations in numerous organ systems, including glomerulonephritis. Patients with more severe HSP-associated glomerulonephritis may develop chronic renal failure. Currently, no widely accepted treatment protocols exist for patients with...

    journal_title:American journal of nephrology

    pub_type: 临床试验,杂志文章

    doi:10.1159/000046235

    authors: Flynn JT,Smoyer WE,Bunchman TE,Kershaw DB,Sedman AB

    更新日期:2001-03-01 00:00:00

  • Spontaneous improvement of the renal function in a patient with HIV-associated focal glomerulosclerosis.

    abstract::Collapsing glomerulopathy is a pattern of renal injury that is seen in association with human immunodeficiency virus (HIV) infection. Patients with this HIV-associated nephropathy (HIVAN) present nephrotic syndrome and rapid deterioration of the renal function. There is no proven effective therapy for HIVAN, and the m...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000065229

    authors: Morales E,Martinez A,Sánchez-Ayuso J,Gutierrez E,Mateo S,Martínez MA,Herrero JC,Praga M

    更新日期:2002-07-01 00:00:00

  • Sevoflurane protects against acute kidney injury in a small-size liver transplantation model.

    abstract:BACKGROUND:Living donor liver transplantation (LDLT) patients run the risk of developing acute kidney injury (AKI) and subsequent chronic kidney disease, affecting morbidity and mortality. Sevoflurane has anti-inflammation properties, and renal ischemia/reperfusion under sevoflurane anesthesia resulted in drastic impro...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000319623

    authors: Kong HY,Zhu SM,Wang LQ,He Y,Xie HY,Zheng SS

    更新日期:2010-01-01 00:00:00

  • Use of tissue Doppler to assess right ventricle function in hemodialysis patients.

    abstract:AIMS:Although there are plenty of data about the differences in left ventricular tissue Doppler (TD) velocities by preload reduction, only a few studies regarding right ventricular function are found in the literature. We investigated the effect of intravascular volume reduction on right ventricular function by ultrafi...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000086080

    authors: Arinc H,Gunduz H,Tamer A,Ozhan H,Akdemir R,Saglam H,Oguzhan A,Uyan C

    更新日期:2005-05-01 00:00:00

  • Rapidly progressive interstitial renal fibrosis associated with Chinese herbal medications.

    abstract:BACKGROUND/AIM:Nephropathy after ingestion of Chinese herbs is known as a rapidly progressive form of interstitial renal fibrosis after a slimming regimen containing aristolochic acid that was identified first in Belgium. Intake of traditional Chinese herbal medicines is very popular in Taiwan. So we looked for similar...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000046647

    authors: Chang CH,Wang YM,Yang AH,Chiang SS

    更新日期:2001-11-01 00:00:00

  • Population-based screening for family history of end-stage renal disease among incident dialysis patients.

    abstract:BACKGROUND:We determined the familial aggregation of end-stage renal disease (ESRD) in a large, population-based sample of incident ESRD cases to assess the feasibility of developing a targeted screening and prevention program directed at members of families at high risk for kidney disease. METHODS:Between January 1, ...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000088491

    authors: Freedman BI,Volkova NV,Satko SG,Krisher J,Jurkovitz C,Soucie JM,McClellan WM

    更新日期:2005-11-01 00:00:00

  • Significant racial differences in the key factors associated with early graft loss in kidney transplant recipients.

    abstract:BACKGROUND:There is continued and significant debate regarding the salient etiologies associated with graft loss and racial disparities in kidney transplant recipients. METHODS:This was a longitudinal cohort study of all adult kidney transplant recipients, comparing patients with early graft loss (<5 years) to those w...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000363393

    authors: Taber DJ,Douglass K,Srinivas T,McGillicuddy JW,Bratton CF,Chavin KD,Baliga PK,Egede LE

    更新日期:2014-01-01 00:00:00

  • Urinary calcium excretion at extremes of sodium intake in normal man.

    abstract::To elucidate the relationship between the renal regulation of sodium and calcium excretion at extremes of sodium intake, we studied 6 normal men ingesting a fixed, 400 mg/day calcium intake and four levels of sodium intake from 10 to 1,500 mEq/day. Serum ionized calcium was not influenced by sodium intake. Blood press...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000166496

    authors: McCarron DA,Rankin LI,Bennett WM,Krutzik S,McClung MR,Luft FC

    更新日期:1981-01-01 00:00:00

  • Profound persistent eosinophilia in a patient with spontaneous renal atheroembolic disease.

    abstract::We describe an elderly women who died of renal failure secondary to spontaneous renal atheroembolic disease. The sole clinical clue to this diagnosis was a profound eosinophilia up to 19,100/mm3 and a relative eosinophil count of 80%. Renal atheroembolic disease should be a prominent consideration in any patient with ...

    journal_title:American journal of nephrology

    pub_type: 杂志文章,评审

    doi:10.1159/000168476

    authors: Levine J,Rennke HG,Idelson BA

    更新日期:1992-01-01 00:00:00

  • Measurement of glomerular filtration rate using nonradioactive Iohexol: comparison of two one-compartment models.

    abstract::Radioisotopic methods for the determination of the glomerular filtration rate (GFR) are highly accurate but require the collection of multiple blood and urine samples and are costly to perform due to personnel, material, and analysis costs. Nonradioactive methods of GFR determination have the potential of minimizing p...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000168985

    authors: Rocco MV,Buckalew VM Jr,Moore LC,Shihabi ZK

    更新日期:1996-01-01 00:00:00

  • Dietary Sodium/Potassium Intake Does Not Affect Cognitive Function or Brain Imaging Indices.

    abstract:BACKGROUND:Dietary sodium may influence cognitive function through its effects on cerebrovascular function and cerebral blood flow. METHODS:The aim of this study was to evaluate the association of dietary sodium intake with cognitive decline in community-dwelling older adults. We also evaluated the associations of die...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000486580

    authors: Nowak KL,Fried L,Jovanovich A,Ix J,Yaffe K,You Z,Chonchol M

    更新日期:2018-01-01 00:00:00

  • Treatment of acute cyanide intoxication with hemodialysis.

    abstract::A dramatic response was noted in a patient at our hospital who received hemodialysis therapy for severe acidosis secondary to an unknown toxin, subsequently identified as cyanide. We were unable to find any information concerning the hemodialysis clearance and extraction ratio of cyanide; thus, we studied the effect o...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000166918

    authors: Wesson DE,Foley R,Sabatini S,Wharton J,Kapusnik J,Kurtzman NA

    更新日期:1985-01-01 00:00:00

  • Gut Microbiota Dysbiosis in Children with Relapsing Idiopathic Nephrotic Syndrome.

    abstract:BACKGROUND:While the etiology of idiopathic nephrotic syndrome (idiopathic nephrotic syndrome [INS]; characterized by repeated relapses and comorbid allergic conditions) remains unknown, recent evidence suggests that dysfunction in regulatory T cells (Tregs) plays an important role in the development of INS as well as ...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000487557

    authors: Tsuji S,Suruda C,Hashiyada M,Kimata T,Yamanouchi S,Kitao T,Kino J,Akane A,Kaneko K

    更新日期:2018-01-01 00:00:00

  • Immunological aspects of a case of posttransplant lymphoproliferative disorder.

    abstract::We describe a female renal transplant recipient with cytomegalovirus and Epstein-Barr virus (EBV) infections who developed aggressive polymorphous polyclonal B cell proliferation. She received two courses of OKT3. We found a majority of transformed B cells bearing EBV membrane receptor CR2 and EBV nuclear antigen. Pos...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000168818

    authors: Franco A,Muñoz C,Aranda I,Cabezas A,Perdiguero M,Prados C

    更新日期:1995-01-01 00:00:00

  • Role of hypertension in coronary artery disease.

    abstract::Historically, stroke, heart failure and renal insufficiency were seen as the major complications of untreated hypertension. More recently, it has become evident that coronary heart disease is probably the most common outcome of this condition. Unlike the other complications of hypertension, coronary events have not be...

    journal_title:American journal of nephrology

    pub_type: 杂志文章,评审

    doi:10.1159/000169000

    authors: Weber MA

    更新日期:1996-01-01 00:00:00

  • Effect of pioglitazone on survival and renal function in a mouse model of polycystic kidney disease.

    abstract:BACKGROUND/AIMS:Cystic epithelia in polycystic kidney disease display features similar to malignant cells. Thiazolidinediones have been shown to have anti-neoplastic properties, therefore we tested the hypothesis that pioglitazone reduces cyst formation, improves renal function, and prolongs survival in a mouse model o...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000242432

    authors: Raphael KL,Strait KA,Stricklett PK,Baird BC,Piontek K,Germino GG,Kohan DE

    更新日期:2009-01-01 00:00:00

  • Arkadia-Smad7-mediated positive regulation of TGF-beta signaling in a rat model of tubulointerstitial fibrosis.

    abstract:BACKGROUND/AIMS:Upregulation of transforming growth factor beta (TGF-beta)/Smad signaling has been implicated in the primary pathogenesis of renal fibrosis. The ubiquitin-proteasome pathway has an important influence on TGF-beta signaling through regulating Smad degradation. As E3 ubiquitin ligases, both Arkadia and Sm...

    journal_title:American journal of nephrology

    pub_type: 杂志文章

    doi:10.1159/000100518

    authors: Liu FY,Li XZ,Peng YM,Liu H,Liu YH

    更新日期:2007-01-01 00:00:00