Plasma exchange in the treatment of early recurrent focal glomerulosclerosis after renal transplantation. Report and review.

Abstract:

:We report a 29-year-old female with recurrent focal glomerulosclerosis (FGS) presenting as heavy proteinuria immediately following renal transplantation. From day 13 after transplantation, daily plasma exchange was performed 6 times. Proteinuria decreased from 13 to 0.2 g/day after plasma exchange and remained to be less than 0.1 g/day even 20 months thereafter. Our review of the literature on the use of plasma exchange in treating recurrent FGS suggests this procedure is not useful in patients whose allograft biopsy showed advanced glomerular sclerotic lesions. We propose early plasma exchange may be a therapeutic option in those patients who have no sclerotic lesions in their allograft biopsy.

journal_name

Am J Nephrol

authors

Li PK,Lai FM,Leung CB,Lui SF,Wang A,Lai KN

doi

10.1159/000168637

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

289-92

issue

4

eissn

0250-8095

issn

1421-9670

journal_volume

13

pub_type

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