Anticardiolipin antibodies in South African patients with lupus nephritis: a clinical and renal pathological study.

abstract：AIM:To develop and assess a semiautomated method for segmenting and counting individual renal cysts from mid-slice MR images in patients with autosomal dominant polycystic kidney disease (ADPKD). METHODS:A semiautomated method was developed to segment and count individual renal cysts from mid-slice MR images in 241 su...

journal_title：American journal of nephrology

authors： Bae KT,Sun H,Lee JG,Bae K,Wang J,Tao C,Chapman AB,Torres VE,Grantham JJ,Mrug M,Bennett WM,Flessner MF,Landsittel DP,Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease.

更新日期：2014-01-01 00:00:00

abstract：:Recent studies have focused attention on the possible role of zinc depletion in the pathogenesis of uremic symptoms such as dysgeusia and impotence. The present studies were undertaken to evaluate the prevalence of zinc deficiency and abnormalities of zinc metabolism in patients with end-stage renal disease. A total o...

journal_title：American journal of nephrology

authors： Muirhead N,Kertesz A,Flanagan PR,Hodsman AB,Hollomby DJ,Valberg LS

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Tacrolimus has been reported to be effective in refractory nephrotic syndrome, such as focal segmental glomerulosclerosis and membranous nephropathy. Some IgA nephropathy (IgAN) patients with massive proteinuria showed resistance to steroids and/or cytotoxic immunosuppressants based on the supportive therapy...

journal_title：American journal of nephrology

authors： Zhang Q,Shi SF,Zhu L,Lv JC,Liu LJ,Chen YQ,Zhang H,Wang HY

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Oxidative stress and inflammation are known to play central roles in the development of diabetic nephropathy (DN). Febuxostat is a novel non-purine xanthine oxidase (XO)-specific inhibitor developed to treat hyperuricemia. In this study, we investigated whether febuxostat could ameliorate DN via renoprotecti...

journal_title：American journal of nephrology

authors： Lee HJ,Jeong KH,Kim YG,Moon JY,Lee SH,Ihm CG,Sung JY,Lee TW

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Growth hormone (GH) resistance in CKD is partly due to increased expression of SOCS2, a GH signaling negative regulator. In SOCS2 absence, body growth is exaggerated. However, GH overexpression in mice causes glomerulosclerosis. Accordingly, we tested whether lack of SOCS2 improves body growth, but accelerat...

journal_title：American journal of nephrology

authors： Landau D,Assadi MH,Abu Hilal R,Chen Y,Rabkin R,Segev Y

更新日期：2020-01-01 00:00:00

abstract：:Atherosclerotic diseases (ASD) are the major cause of mortality and morbidity in patients on hemodialysis (HD). To evaluate the significance and usefulness of atherogenic indices, we examined lipoprotein(a) (Lp(a)), remnant-like particles cholesterol (RLP.C), homocysteine (Hcy), cardiac troponin T (TnT), and ankle-arm...

journal_title：American journal of nephrology

authors： Oishi K,Nagake Y,Yamasaki H,Fukuda S,Ichikawa H,Ota K,Makino H

更新日期：2000-03-01 00:00:00

abstract：:During the period from April 4, 1988, to April 20, 1988, nine pyrogenic reactions and five gram-negative bacteremias occurred in 11 patients undergoing dialysis. All pyrogenic reactions and gram-negative bacteremias occurred among patients in whom a reprocessed dialyzer was used. The rate of pyrogenic reactions or bac...

journal_title：American journal of nephrology

authors： Beck-Sague CM,Jarvis WR,Bland LA,Arduino MJ,Aguero SM,Verosic G

更新日期：1990-01-01 00:00:00

abstract：INTRODUCTION:Evidence using real-world data is sparse regarding the effects of oral anticoagulants (OACs) among patients with kidney disease. The aim of this study was to investigate the effects of kidney disease on ischemic stroke (IS) or systemic embolism (SE) among patients taking OAC, using large-scale real-world d...

journal_title：American journal of nephrology

authors： Maeda T,Nishi T,Funakoshi S,Tada K,Tsuji M,Satoh A,Kawazoe M,Yoshimura C,Arima H

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The identification of nephrin and CD2AP, podocyte proteins which modulate the properties of glomerular barrier selectivity, has made it possible to unravel the mechanisms undergoing foot process effacement and proteinuria. Here we explored the role of nephrin and CD2AP together with the integrity of the slit...

journal_title：American journal of nephrology

authors： Gagliardini E,Benigni A,Tomasoni S,Abbate M,Kalluri R,Remuzzi G

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:There is continued and significant debate regarding the salient etiologies associated with graft loss and racial disparities in kidney transplant recipients. METHODS:This was a longitudinal cohort study of all adult kidney transplant recipients, comparing patients with early graft loss (<5 years) to those w...

journal_title：American journal of nephrology

authors： Taber DJ,Douglass K,Srinivas T,McGillicuddy JW,Bratton CF,Chavin KD,Baliga PK,Egede LE

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Contemporary prevalence of chronic kidney disease (CKD) and thrombotic cardiovascular (CV) events remains unclear in Veterans enrolled in the Veterans Affairs Health Care System (VA) care. Although oral P2Y12 inhibitors (P2Y12i) are increasingly being prescribed to this patient population, the overall prescr...

journal_title：American journal of nephrology

authors： Singh M,Raghavan D,Williams JS,Martin BC,Hudson TJ,Owen RR,Jain N

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:To evaluate the predictive value of dialysate interleukin-6 (IL-6) representing local subclinical intraperitoneal inflammation for the development of peritonitis in continuous ambulatory peritoneal dialysis (CAPD) patients. METHODS:Stable prevalent CAPD patients were enrolled in this prospective study. IL-6...

journal_title：American journal of nephrology

authors： Yang X,Tong Y,Yan H,Ni Z,Qian J,Fang W

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Serum creatinine (SCr) levels are decreased following traumatic amputation, leading to the overestimation of glomerular filtration rate (GFR). β-Trace protein (BTP) and β2-microglobulin (B2M) strongly correlate with measured GFR and have not been studied following amputation. We hypothesized that BTP and B2M...

journal_title：American journal of nephrology

authors： Little DJ,Yuan CM,Thurlow JS,Gounden V,Doi SQ,Pruziner A,Abbott KC,Theeler BJ,Olson SW

更新日期：2015-01-01 00:00:00

abstract：:Radioisotopic methods for the determination of the glomerular filtration rate (GFR) are highly accurate but require the collection of multiple blood and urine samples and are costly to perform due to personnel, material, and analysis costs. Nonradioactive methods of GFR determination have the potential of minimizing p...

journal_title：American journal of nephrology

authors： Rocco MV,Buckalew VM Jr,Moore LC,Shihabi ZK

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND/AIM:Slc26a6 (PAT1, CFEX) is a major chloride/base exchanger located on the apical membrane of the kidney proximal tubule. The purpose of the present study was to examine the effect of Slc26a6 deletion on the apical Na+/H+ exchanger 3 (NHE3) in the straight segment (S3) of the proximal tubule, which is the ma...

journal_title：American journal of nephrology

authors： Petrovic S,Barone S,Wang Z,McDonough AA,Amlal H,Soleimani M

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND/AIMS:The association between chronic kidney disease (CKD) awareness and healthy behaviors is unknown. We examined whether CKD self-recognition is associated with healthy behaviors and achieving risk-reduction targets known to decrease risk of cardiovascular morbidity and CKD progression. METHODS:CKD awarene...

journal_title：American journal of nephrology

authors： Tuot DS,Plantinga LC,Judd SE,Muntner P,Hsu CY,Warnock DG,Gutiérrez OM,Safford M,Powe NR,McClellan WM,REGARDS Investigators.

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Home dialysis patients may be at an increased risk of adverse events after transitional states. The home dialysis virtual ward (HDVW) trial was conducted in Canadian dialysis centers and aimed to evaluate potential care gaps and patient satisfaction during the HDVW. METHODS:The HDVW was a multicenter single...

journal_title：American journal of nephrology

authors： Nadeau-Fredette AC,Chan CT,Bargman JM,Copland MA,Finkle SN,Oliver MJ,Pauly RP,Perl J,Shah NA,Zimmerman DL,Tennankore KK

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:It is uncertain whether kidneys from marginal donors are suitable for live kidney transplantation. In deceased donor kidneys, tubular cell senescence affects allograft function. However, the degree of cell senescence in a living donor kidney with marginal factors has not been reported. In this study, we asse...

journal_title：American journal of nephrology

authors： Sofue T,Kushida Y,Ozaki T,Moritoki M,Nishijima Y,Ohsaki H,Ueda N,Kakehi Y,Nishiyama A,Minamino T

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Hyperoxaluria may result from increased endogenous production or overabsorption of dietary oxalate in the gastrointestinal tract leading to nephrolithiasis and, in some, to oxalate nephropathy and chronic kidney disease. ALLN-177 is an oral formulation of a recombinant, oxalate specific, microbial enzyme oxa...

journal_title：American journal of nephrology

authors： Langman CB,Grujic D,Pease RM,Easter L,Nezzer J,Margolin A,Brettman L

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:We examined the correlations between renal biopsy findings in Wegener's granulomatosis and renal function at baseline and 1 year in 22 patients who presented between 1988 and 1999. METHODS:Renal histology was independently reviewed by 2 pathologists who were masked to the clinical data. The primary out...

journal_title：American journal of nephrology

authors： Haroun MK,Stone JH,Nair R,Racusen L,Hellmann DB,Eustace JA

更新日期：2002-09-01 00:00:00

abstract：:This study investigated the possible beneficial effect of intraperitoneal proteolytic enzyme administration on the development of hypertension-induced renal injury in the rat model of 2-kidney 1-clip (2K1C) Goldblatt hypertension. Male Wistar rats (120-150 g) underwent either sham surgery (control, n = 5) or clipping ...

journal_title：American journal of nephrology

authors： Sebeková K,Dämmrich J,Fierlbeck W,Krivosiková Z,Paczek L,Heidland A

更新日期：1998-01-01 00:00:00

abstract：:Skin ulceration is a well-characterized thrombotic complication of the heparin-induced thrombocytopenia (HIT) syndrome. We present the case of a 73-year-old diabetic woman nearing end-stage renal failure who developed extensive upper thigh, abdominal and buttock ulceration following initiation of subcutaneous heparin ...

journal_title：American journal of nephrology

authors： Denton MD,Mauiyyedi S,Bazari H

更新日期：2001-07-01 00:00:00

abstract：:Two patients are reported who presented within the first 3 months posttransplantation with acute bone pain where serial magnetic resonance imaging (MRI) allowed differentiation between bone edema, which resolved spontaneously, and avascular necrosis (AVN) requiring core decompression. Case 1 had ill-defined images con...

journal_title：American journal of nephrology

authors： Pilmore H,Walker R,McMillan B,Paranjpe D,Berkeley B

更新日期：1998-01-01 00:00:00

abstract：:To evaluate the determinants of rhabdomyolysis in the diabetic state, we compared biochemical and clinical features of diabetic patients with (group 1, 41 patients) and without (group 2, 36 patients) rhabdomyolysis. There was no difference in values for serum potassium, bicarbonate, phosphate and calcium between the t...

journal_title：American journal of nephrology

authors： Singhal PC,Abramovici M,Ayer S,Desroches L

更新日期：1991-01-01 00:00:00

abstract：:Peritoneal sclerosis, a disorder similar to that previously identified in nonuremic patients, is being noted in peritoneal dialysis patients with increasing frequency. The etiology in dialysis patients remains unknown. An association with previous or ongoing peritoneal inflammation or irritation suggests that the inci...

journal_title：American journal of nephrology

authors： Ing TS,Daugirdas JT,Gandhi VC

更新日期：1984-01-01 00:00:00

abstract：:In this paper, we analyze the collection of ancient Greek treatises ascribed to Hippocrates (460; between 371 and 350 BC), in order to determine whether or not edema can be traced. As a result of reading these works on the Greek text, we recognize some symptoms of edema in those called oidêma (swelling) and udrôps (dr...

journal_title：American journal of nephrology

authors： Touwaide A,De Santo NG

更新日期：1999-01-01 00:00:00

abstract：:A patient with unilateral gross hematuria was found to have mesangial proliferation and IgM deposition on renal biopsy, consistent with the entity of primary renal hematuria. This case refutes previous assumptions that renal biopsy is normal in patients with unilateral hematuria. Glomerular lesions may be more common ...

journal_title：American journal of nephrology

authors： Tapp DC,Whitaker WR,Copley JB

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND/AIMS:Patients on chronic hemodialysis have a high prevalence of heart disease and poor self-reported physical function. The association between structural heart disease and self-reported physical function in patients on hemodialysis is unknown. METHODS:We studied the association between elevated pulmonary a...

journal_title：American journal of nephrology

authors： Abreo AP,Herzog CA,Kutner NG,Lea J,Johansen KL

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Hypercholesterolemia is one of the major manifestations of nephrotic syndrome. We have previously shown that nephrotic hypercholesterolemia is associated with and, in part, due to dysregulation of hepatic HMG-CoA reductase, acyl-CoA:cholesterol acyltransferase (ACAT) and cholesterol 7alpha-hydroxylase, as we...

journal_title：American journal of nephrology

authors： Vaziri ND,Liang K

更新日期：2004-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVE:In the Systolic Blood Pressure Intervention Trial, the possible relationships between acute kidney injury (AKI) and risk of major cardiovascular events and death are not known. STUDY DESIGN:Post hoc analysis of a multicenter, randomized, controlled, open-label clinical trial. SETTING AND PARTI...

journal_title：American journal of nephrology

authors： Dieter BP,Daratha KB,McPherson SM,Short R,Alicic RZ,Tuttle KR

更新日期：2019-01-01 00:00:00