Abstract:
:To define the incidence of non-A, non-B (NANB) hepatitis and evaluate possible risk factors, we reviewed records of 163 patients on chronic dialysis during a 3-year period. 23 cases of NANB hepatitis occurred, 13 (27%) in 49 center dialysis, 8 (10%) in 77 home hemodialysis (p less than 0.02) and 2 (5%) in 37 peritoneal dialysis patients (p less than 0.01). Hepatitis patients received significantly more transfusions than controls. Numbers of transfusions and of patients transfused were not significantly different in center patients compared to home and peritoneal. 8 NANB patients received no transfusions. NANB was the most common cause of hepatitis in our unit (68%). Although transfusions were a likely etiologic factor, to explain the increased risk in center dialysis patients, disease in patients not transfused and development of NANB hepatitis without a known parenteral exposure in a physician assigned to the Nephrology Service, we feel another etiologic factor was important, the dialysis center.
journal_name
Am J Nephroljournal_title
American journal of nephrologyauthors
Seaworth BJ,Garrett LE,Stead WW,Hamilton JDdoi
10.1159/000166815subject
Has Abstractpub_date
1984-01-01 00:00:00pages
235-9issue
4eissn
0250-8095issn
1421-9670journal_volume
4pub_type
杂志文章abstract::Hyperlipidemia is common in patients with glomerular proteinuria. It may contribute to atherosclerotic complications and accelerate glomerular damage. Early trials of the fibric acid derivative clofibrate led to a myositis syndrome causing many nephrologists to abandon attempts at treatment of nephrotic hyperlipidemia...
journal_title:American journal of nephrology
pub_type: 临床试验,杂志文章,评审
doi:10.1159/000168204
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Steroid therapy has become an effective option for patients with primary Sjogren's syndrome with tubulointerstitial nephritis (TIN), while the use of cytotoxic agents is still debated. Our study aimed to compare the clinical outcomes of patients treated with cyclophosphamide (CTX) combined with glucocorticoi...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000484903
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Prolonged use of corticosteroids continues to be the mainstay in the management of most proteinuric glomerulopathies, but is limited by extensive side effects. Alternative medications such as adrenocorticotropic hormone (ACTH) have been recently used to treat refractory glomerulopathies and have shown superi...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000506854
更新日期:2020-01-01 00:00:00
abstract::John Bostock has a reasonable claim to being one of the first chemical pathologists. Most of his work was done before that of William Prout, with whom both he and Bright were in contact. Bostock's work was done about the same time as that of his friends and colleagues Marcet and Wollaston. Although other, notably Crui...
journal_title:American journal of nephrology
pub_type: 传,历史文章,杂志文章
doi:10.1159/000168749
更新日期:1994-01-01 00:00:00
abstract::The platelet content of adenosine triphosphate (ATP), adenosine diphosphate (ADP), serotonin and ouabain-insensitive, magnesium-dependent adenosine triphosphatase (ATPase) was determined in patients with chronic renal failure, patients on chronic hemodialysis, and kidney transplant recipients. Platelet ATP content was...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000166482
更新日期:1981-01-01 00:00:00
abstract::A renal transplant recipient with a remote history of end-stage renal disease due to postpartum hemolytic-uremic syndrome (HUS) presented with acute renal failure after having stable renal allograft function for 9 years. A diagnosis of thrombotic microangiopathy was made based on clinical and histologic findings at re...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000169094
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Fibrillary glomerulonephritis is characterized by randomly arranged fibrils, approximately 20 nm in diameter by electron microscopy. Patients present with proteinuria, hematuria and kidney insufficiency, and about half of the reported patients progress to end-stage kidney disease within 4 years. The dependen...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000455390
更新日期:2017-01-01 00:00:00
abstract::The relationship between abnormalities in nocturnal penile tumescence (NPT) and autonomic function, measured by the Valsalva maneuver, was evaluated in 25 uremic patients and 22 normal subjects. NPT in uremic patients (45 +/- 6.8 min/night) was lower (p less than 0.01) than in normals (85 +/- 10.4 min/night). Valsalva...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000166629
更新日期:1982-01-01 00:00:00
abstract::We have recently described that in the erythrocytes from uremic patients on chronic hemodialysis, the pentose-phosphate shunt is defective, the membrane concentrations of malonyldialdehyde, resulting from peroxidation of polyunsaturated fatty acids in the membranes themselves, are increased, and the concentrations of ...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000167061
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:The impact of socioeconomic factors on arteriovenous fistula (AVF) creation in hemodialysis (HD) patients is not well understood. We assessed the association of area and individual-level indicators of poverty and health care insurance on AVF use among incident end-stage renal disease (ESRD) patients initiate...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000441804
更新日期:2015-01-01 00:00:00
abstract::We assessed blood volume (BV) in 20 edematous patients with nephrotic syndrome and in 32 subjects without renal or other disease liable to induce BV variation. Two methods were chosen, one using 131I-albumin and the other 51Cr red blood cells. Among the 20 patients, 11 presented minimal-change lesions, and 9 had histo...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000167967
更新日期:1989-01-01 00:00:00
abstract::We describe a 78-year-old patient with nephrotic syndrome due to minimal-change glomerulopathy, associated with a renal adenocarcinoma. Oliguric acute renal failure requiring hemodialysis was also observed. Surgical removal of the tumor and corticosteroid therapy resulted in resolution of the nephrotic state and impro...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000013365
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND/AIMS:Intradialytic hypotension is the most common complication of modern day haemodialysis (HD). Convective modalities, including haemodiafiltration (HDF) are reported to result in greater cardiovascular stability compared to standard HD, which has been suggested to be due to improved solute transport betwee...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000349925
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND/AIMS:Three different apo E alleles (E2, E3 and E4) produce apo E isoproteins, which regulate the metabolism of lipoproteins. This study investigated the apo E polymorphisms as a prognostic factor for the development of diabetic nephropathy (DN). METHODS:A total of 525 type 2 diabetic patients were enrolled ...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000324561
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Predicting the mortality risk of patients un-dergoing hemodialysis (HD) is challenging. Cell-free DNA (cfDNA) is released into circulation from dying cells, and its elevation is predictive of unfavorable outcome. In a pilot study, we found post-HD cfDNA level to be a predictor of all-cause mortality. Thus, t...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000510771
更新日期:2020-01-01 00:00:00
abstract::This study describes 10 cases of IgM nephropathy in whom the main morphological findings consisted of diffuse mesangial deposition of IgM and varying degrees of mesangial cell proliferation. In addition, focal segmental sclerosis was present in 1 patient and global sclerosis in another. An ill-defined electron-dense d...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000167485
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:There is a higher risk of gastrointestinal (GI) bleeding in patients treated with dabigatran versus warfarin. We analyzed the impact of renal function on the relative risk of bleeding in patients converted to dabigatran. METHODS:Patients aged ≥65 years who received anticoagulation with warfarin for a minimu...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000446848
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND/AIMS:Few published data describe survival rates for pediatric end-stage renal disease (ESRD) patients. We aimed to describe one-year mortality rates for US pediatric ESRD patients over a 15-year period. METHODS:In this retrospective cohort study, we used the US Renal Data System database to identify period-...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000380828
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Medullary sponge kidney (MSK) is characterized by malformation of the terminal collecting ducts and is associated with an increased risk of nephrolithiasis, nephrocalcinosis, urinary tract infections, renal acidification defects, and reduced bone density. It has been historically diagnosed with intravenous p...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000358496
更新日期:2014-01-01 00:00:00
abstract::Berengario da Carpi was magister of anatomy and surgery at the University of Bologna from 1502 to 1527. Eustachio and Falloppia defined him as 'the restaurator of anatomy'. He was a great surgeon, anatomist and physician of illustrious patients including Lorenzo II dei Medici, Giovanni dalle Bande Nere, Galeazzo Palla...
journal_title:American journal of nephrology
pub_type: 传,历史文章,杂志文章
doi:10.1159/000013452
更新日期:1999-01-01 00:00:00
abstract::Shortage of kidney donor is still a major limitation for renal transplantation programs. This review focuses on the emerging practices, adopted to increase transplant activities, of expanding the criteria for donor and recipient selection without exposing the recipient to the drawbacks of a graft with inadequate nephr...
journal_title:American journal of nephrology
pub_type: 杂志文章,评审
doi:10.1159/000072055
更新日期:2003-07-01 00:00:00
abstract::A variety of histologic changes have been observed in the kidneys of patients with light-chain deposition disease. We report 3 cases with kappa light chain deposition who presented with diverse clinical, histological, and ultrastructural features. All the cases were diagnosed by the presence of monoclonal kappa light ...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000167600
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND/AIMS:Current status of primary hyperoxaluria (PH) has not been surveyed in Japan. METHODS:Japanese patients with PH were reviewed in the published literature. RESULTS:Fifty-nine patients were diagnosed as PH from 1962 to 2003. The median ages both at diagnosis and at the onset of initial symptoms were 17 (...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000086361
更新日期:2005-05-01 00:00:00
abstract:INTRODUCTION:Evidence using real-world data is sparse regarding the effects of oral anticoagulants (OACs) among patients with kidney disease. The aim of this study was to investigate the effects of kidney disease on ischemic stroke (IS) or systemic embolism (SE) among patients taking OAC, using large-scale real-world d...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000509567
更新日期:2020-01-01 00:00:00
abstract::In general, nonrheumatic atrial fibrillation is associated with a high risk of stroke. However, its impact on stroke in the setting of chronic hemodialysis treatment is insufficiently addressed in the literature. We assessed the incidence of stroke among 430 chronic hemodialysis patients and the impact of atrial fibri...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000046216
更新日期:2001-01-01 00:00:00
abstract:AIM:The relation of ambient temperature (AMT) and relative humidity to systolic blood pressure (SBP), diastolic blood pressure (DBP), body weight (BW), and body weight gain between dialysis sessions (DeltaBW) was examined in hemodialysis patients by Fourier analysis. METHODS AND RESULTS:The authors recruited 144 dialy...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000013538
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Data concerning long-term mortality predictors among large, purely diabetic hemodialysis collectives are scarce. METHODS:We used data from a multicenter, prospective, randomized trial among 1,255 hemodialysis patients with type 2 diabetes mellitus (T2DM) and its observational follow-up study. The associatio...
journal_title:American journal of nephrology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1159/000485842
更新日期:2018-01-01 00:00:00
abstract::We have demonstrated considerable variability in the volumes of different glomeruli in given individuals (individual glomerular volume: IGV) in a stereologic study of kidneys at forensic autopsy performed to investigate sudden or unexpected death in people without manifest kidney disease. We review some important asso...
journal_title:American journal of nephrology
pub_type: 杂志文章,评审
doi:10.1159/000327044
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:While chronic dialysis treatment has been suggested to increase pulmonary pressure values, right ventricular dysfunction (RVD) is a major cause of death in patients with end-stage renal disease. We investigated the impact of different dialysis treatments on right ventricular function. METHODS:We examined 22...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000320755
更新日期:2010-01-01 00:00:00
abstract:AIMS:This study was conducted prospectively to ascertain the prevalence of anticardiolipin antibodies (ACAs) in patients with lupus nephritis and to determine whether this subgroup of patients differed clinically and histologically from patients without the antibody. PATIENTS AND METHODS:40 SLE patients (26 Blacks, 14...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000013615
更新日期:2000-09-01 00:00:00