Abstract:
BACKGROUND/AIMS:Few published data describe survival rates for pediatric end-stage renal disease (ESRD) patients. We aimed to describe one-year mortality rates for US pediatric ESRD patients over a 15-year period. METHODS:In this retrospective cohort study, we used the US Renal Data System database to identify period-prevalent cohorts of patients aged younger than 19 for each year during the period 1995-2010. Yearly cohorts averaged approximately 1,200 maintenance dialysis patients (60% hemodialysis, 40% peritoneal dialysis) and 1,100 transplant recipients. Patients were followed for up to 1 year and censored at change in modality, loss to follow-up, or death. We calculated the unadjusted model-based mortality rates per time at risk, within each cohort year, by treatment modality (hemodialysis, peritoneal dialysis, transplant) and patient characteristics; percentage of deaths by cause; and overall adjusted odds of mortality by characteristics and modality. RESULTS:Approximately 50% of patients were in the age group 15-18, 55% were male, and 45% were female. The most common causes of ESRD were congenital/reflux/obstructive causes (55%) and glomerulonephritis (30%). One-year mortality rates showed evidence of a decrease in the number of peritoneal dialysis patients (6.03 per 100 patient-years, 1995; 2.43, 2010; p = 0.0263). Mortality rates for transplant recipients (average 0.68 per 100 patient-years) were consistently lower than the rates for all dialysis patients (average 4.36 per 100 patient-years). CONCLUSIONS:One-year mortality rates differ by treatment modality in pediatric ESRD patients.
journal_name
Am J Nephroljournal_title
American journal of nephrologyauthors
Chavers BM,Molony JT,Solid CA,Rheault MN,Collins AJdoi
10.1159/000380828subject
Has Abstractpub_date
2015-01-01 00:00:00pages
121-8issue
2eissn
0250-8095issn
1421-9670pii
000380828journal_volume
41pub_type
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journal_title:American journal of nephrology
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journal_title:American journal of nephrology
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doi:10.1159/000166711
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pub_type: 杂志文章
doi:10.1159/000341914
更新日期:2012-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1159/000336308
更新日期:2012-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1159/000341862
更新日期:2012-01-01 00:00:00
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journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000166799
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pub_type: 杂志文章
doi:10.1159/000168357
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journal_title:American journal of nephrology
pub_type: 杂志文章,评审
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更新日期:1987-01-01 00:00:00
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journal_title:American journal of nephrology
pub_type: 杂志文章,评审
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更新日期:1996-01-01 00:00:00
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更新日期:2017-01-01 00:00:00
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journal_title:American journal of nephrology
pub_type: 杂志文章,评审
doi:10.1159/000354893
更新日期:2013-01-01 00:00:00
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journal_title:American journal of nephrology
pub_type: 历史文章,杂志文章
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更新日期:1997-01-01 00:00:00
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journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000087824
更新日期:2005-09-01 00:00:00
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journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000119742
更新日期:2008-01-01 00:00:00
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journal_title:American journal of nephrology
pub_type: 杂志文章,meta分析,评审
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