Abstract：
BACKGROUND/AIMS:Few published data describe survival rates for pediatric end-stage renal disease (ESRD) patients. We aimed to describe one-year mortality rates for US pediatric ESRD patients over a 15-year period. METHODS:In this retrospective cohort study, we used the US Renal Data System database to identify period-prevalent cohorts of patients aged younger than 19 for each year during the period 1995-2010. Yearly cohorts averaged approximately 1,200 maintenance dialysis patients (60% hemodialysis, 40% peritoneal dialysis) and 1,100 transplant recipients. Patients were followed for up to 1 year and censored at change in modality, loss to follow-up, or death. We calculated the unadjusted model-based mortality rates per time at risk, within each cohort year, by treatment modality (hemodialysis, peritoneal dialysis, transplant) and patient characteristics; percentage of deaths by cause; and overall adjusted odds of mortality by characteristics and modality. RESULTS:Approximately 50% of patients were in the age group 15-18, 55% were male, and 45% were female. The most common causes of ESRD were congenital/reflux/obstructive causes (55%) and glomerulonephritis (30%). One-year mortality rates showed evidence of a decrease in the number of peritoneal dialysis patients (6.03 per 100 patient-years, 1995; 2.43, 2010; p = 0.0263). Mortality rates for transplant recipients (average 0.68 per 100 patient-years) were consistently lower than the rates for all dialysis patients (average 4.36 per 100 patient-years). CONCLUSIONS:One-year mortality rates differ by treatment modality in pediatric ESRD patients.
journal_name
Am J Nephroljournal_title
American journal of nephrologyauthors
Chavers BM,Molony JT,Solid CA,Rheault MN,Collins AJdoi
10.1159/000380828subject
Has Abstractpub_date
2015-01-01 00:00:00pages
121-8issue
2eissn
0250-8095issn
1421-9670pii
000380828journal_volume
41pub_type
杂志文章abstract：BACKGROUND:Used in a variety of approved and off-label indications, there are several intravenous immunoglobulin (IVIG) preparations available which differ in the excipients (e.g. sucrose, glucose, maltose, D-sorbitol, glycine or L-proline) used to stabilize the protein in the solution. A very rare, but severe adverse ...
journal_title：American journal of nephrology
pub_type： 杂志文章,评审
doi：10.1159/000354893
更新日期：2013-01-01 00:00:00
abstract：:The prejunctional beta-adrenoceptors present in the isolated perfused kidney of normotensive rats (NR) and spontaneously hypertensive rats (SHR) were compared and the effects of tertatolol on these receptors were investigated. Kidneys of NR (Wistar + Wistar-Kyoto [WKY]) and SHR, were continuously perfused with Tyrode ...
journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000167330
更新日期：1986-01-01 00:00:00
abstract：:In order to evaluate the changes in causes and outcome of acute renal failure (ARF) during the years 1975-1989, 710 patients treated in our dialysis center were analyzed. We compared the etiology, the severity and catabolic state of ARF, the techniques of renal replacement therapy, which were employed and the ages and...
journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000168466
更新日期：1992-01-01 00:00:00
abstract：BACKGROUND/AIMS:The 7-year Major Adverse Cardiovascular Events Calculator (CRCRTR-MACE) predicts cardiovascular events (CVE) in renal transplant recipients (RTR), and thrombopoietin (TPO) is a humoral inflammatory factor implicated in cardiovascular disease (CVD). The aim of the study was to determine if circulating TP...
journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000377641
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND:Data concerning long-term mortality predictors among large, purely diabetic hemodialysis collectives are scarce. METHODS:We used data from a multicenter, prospective, randomized trial among 1,255 hemodialysis patients with type 2 diabetes mellitus (T2DM) and its observational follow-up study. The associatio...
journal_title：American journal of nephrology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1159/000485842
更新日期：2018-01-01 00:00:00
abstract：:There is evidence to suggest that a renal embryogenesis disorder, with an associated deficit of nephrons, may be the cause of nephropathy later in the lives of patients with Balkan endemic nephropathy (BEN). This evidence includes the renal dysplasia or hypoplasia observed in BEN patients, the high incidence of renal ...
journal_title：American journal of nephrology
pub_type： 历史文章,杂志文章
doi：10.1159/000063771
更新日期：2002-07-01 00:00:00
abstract：:A variety of histologic changes have been observed in the kidneys of patients with light-chain deposition disease. We report 3 cases with kappa light chain deposition who presented with diverse clinical, histological, and ultrastructural features. All the cases were diagnosed by the presence of monoclonal kappa light ...
journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000167600
更新日期：1988-01-01 00:00:00
abstract：BACKGROUND:Recent reports have highlighted that diabetic patients with kidney failure are at increased risk of technique failure and transfer to haemodialysis within 90 days of initiating peritoneal dialysis (PD). We wished to determine whether there were differences between diabetic and non-diabetic patients within th...
journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000477326
更新日期：2017-01-01 00:00:00
abstract：:We describe a female renal transplant recipient with cytomegalovirus and Epstein-Barr virus (EBV) infections who developed aggressive polymorphous polyclonal B cell proliferation. She received two courses of OKT3. We found a majority of transformed B cells bearing EBV membrane receptor CR2 and EBV nuclear antigen. Pos...
journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000168818
更新日期：1995-01-01 00:00:00
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journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000329081
更新日期：2011-01-01 00:00:00
abstract：BACKGROUND:Growth hormone (GH) resistance in CKD is partly due to increased expression of SOCS2, a GH signaling negative regulator. In SOCS2 absence, body growth is exaggerated. However, GH overexpression in mice causes glomerulosclerosis. Accordingly, we tested whether lack of SOCS2 improves body growth, but accelerat...
journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000508224
更新日期：2020-01-01 00:00:00
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journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000330849
更新日期：2011-01-01 00:00:00
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journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000168797
更新日期：1995-01-01 00:00:00
abstract：:During the period from April 4, 1988, to April 20, 1988, nine pyrogenic reactions and five gram-negative bacteremias occurred in 11 patients undergoing dialysis. All pyrogenic reactions and gram-negative bacteremias occurred among patients in whom a reprocessed dialyzer was used. The rate of pyrogenic reactions or bac...
journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000168155
更新日期：1990-01-01 00:00:00
abstract：BACKGROUND:Interest in nephrology careers is declining, possibly due to perceptions of the field and/or training aspects. Understanding practices of medical schools successfully instilling nephrology interest could inform efforts to attract leading candidates to the specialty. METHODS:The American Society of Nephrolog...
journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000501058
更新日期：2019-01-01 00:00:00
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journal_title：American journal of nephrology
pub_type： 杂志文章,评审
doi：10.1159/000342626
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND:Older adults with advanced non-dialysis-dependent chronic kidney disease (NDD-CKD) face a high risk of hospitalization and related adverse events. METHODS:This prospective cohort study followed nephrology clinic patients ≥60 years old with NDD-CKD stages 4-5. After an eligible patient's office visit, study ...
journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000509046
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND/AIMS:Post-renal transplant recurrent glomerulonephritis (GN) contributes to allograft loss. Rituximab treatment has been used in a multidose strategy with variable efficacy and toxicity. We investigated a novel single-dose approach. METHODS:A single center, retrospective, cohort study was conducted between ...
journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000371587
更新日期：2015-01-01 00:00:00
abstract：:Hepatic dysfunction was observed in 34 patients with nontraumatic rhabdomyolysis. The serum levels of lactic dehydrogenase were markedly elevated in all patients. The peak values occurred within 72 h of hospitalization. There was no significant difference among patients with (9,044 +/- 1,154 U/l) and without acute ren...
journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000168053
更新日期：1990-01-01 00:00:00
abstract：:John Bostock has a reasonable claim to being one of the first chemical pathologists. Most of his work was done before that of William Prout, with whom both he and Bright were in contact. Bostock's work was done about the same time as that of his friends and colleagues Marcet and Wollaston. Although other, notably Crui...
journal_title：American journal of nephrology
pub_type： 传,历史文章,杂志文章
doi：10.1159/000168749
更新日期：1994-01-01 00:00:00
abstract：:The substitution of recombinant human erythropoietin (rhEPO) in chronic hemodialysis patients is often associated with the development of severe hypertension. In the present study, a systematical echocardiographic analysis was performed in 25 patients on maintenance hemodialysis during rhEPO therapy for at least 4 mon...
journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000168273
更新日期：1991-01-01 00:00:00
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journal_title：American journal of nephrology
pub_type： 杂志文章,随机对照试验
doi：10.1159/000343140
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND:Hyperkalemia is common in patients receiving maintenance hemodialysis. However, few studies have examined the association between serum potassium level and mortality. METHODS:This study used annual cohorts of hemodialysis patients during 2007-2010. To determine hyperkalemia prevalence, monthly hyperkalemia ...
journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000448341
更新日期：2016-01-01 00:00:00
abstract：AIM:To study the role of the caliceal system in urine flow. METHODS:Eight patients (6 men, 2 women; mean age 42.6 +/- 7.6 years) with an upper polar renal mass (6 renal cysts; 2 hypernephromas) which did not encroach on the pelvicaliceal system were studied. After mass removal, a manometric catheter was introduced int...
journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000013391
更新日期：1998-01-01 00:00:00
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journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000167517
更新日期：1987-01-01 00:00:00
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journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000013538
更新日期：1999-01-01 00:00:00
abstract：:Man-made or massive natural disasters may be followed by 'epidemics' of the muscle crush syndrome. The first descriptions of the crush syndrome were in the German-language literature following the earthquake of Messina in 1909 and World War II. On the threshold of World War II, the English-language literature was stil...
journal_title：American journal of nephrology
pub_type： 历史文章,杂志文章
doi：10.1159/000169127
更新日期：1997-01-01 00:00:00
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journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000094403
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND:The optimal level of serum ferritin (s-ft) for anemia control and good survival in hemodialysis (HD) patients remains unclear. A 10-year survey was performed to clarify the appropriate quantities of s-ft and investigate the relationships among s-ft, transferrin saturation (TSAT), and mortality in HD patients...
journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000370317
更新日期：2014-01-01 00:00:00
abstract：:We analyzed routine serum potassium concentration measurements and conditions temporally associated with abnormalities in potassium concentration in outpatients on chronic hemodialysis (136 nondiabetics, 36 diabetics) and continuous ambulatory peritoneal dialysis (16 nondiabetics, 10 diabetics). The following potassiu...
journal_title：American journal of nephrology
pub_type： 杂志文章
doi：10.1159/000167443
更新日期：1987-01-01 00:00:00
