Rhabdomyolysis among Critically Ill Combat Casualties: Long-Term Outcomes.

abstract：:Historically, stroke, heart failure and renal insufficiency were seen as the major complications of untreated hypertension. More recently, it has become evident that coronary heart disease is probably the most common outcome of this condition. Unlike the other complications of hypertension, coronary events have not be...

journal_title：American journal of nephrology

authors： Weber MA

更新日期：1996-01-01 00:00:00

abstract：:A 50-year-old woman presented with thrombocytopenia, microangiopathic hemolytic anemia, and nephrotic syndrome. Although a high level of circulating immune complexes, mild hypocomplementemia, and the antinuclear antibody also were present, the criteria for collagen disease were not fulfilled. Renal biopsy demonstrated...

journal_title：American journal of nephrology

authors： Kimura M,Fujigaki Y,Ohtake T,Furuya R,Hishida A,Kaneko E

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND/AIMS:Cystic epithelia in polycystic kidney disease display features similar to malignant cells. Thiazolidinediones have been shown to have anti-neoplastic properties, therefore we tested the hypothesis that pioglitazone reduces cyst formation, improves renal function, and prolongs survival in a mouse model o...

journal_title：American journal of nephrology

authors： Raphael KL,Strait KA,Stricklett PK,Baird BC,Piontek K,Germino GG,Kohan DE

更新日期：2009-01-01 00:00:00

abstract：:A variety of histologic changes have been observed in the kidneys of patients with light-chain deposition disease. We report 3 cases with kappa light chain deposition who presented with diverse clinical, histological, and ultrastructural features. All the cases were diagnosed by the presence of monoclonal kappa light ...

journal_title：American journal of nephrology

authors： Venkataseshan VS,Faraggiana T,Hughson MD,Buchwald D,Olesnicky L,Goldstein MH

更新日期：1988-01-01 00:00:00

abstract：:Nutrition has been shown to predict clinical outcome in continuous ambulatory peritoneal dialysis (CAPD) patients. However, despite the positive relationship between KT/V (urea) and the normalised protein catabolic rate, the ability of urea kinetic modelling to predict clinical outcome or nutrition remains inconclusiv...

journal_title：American journal of nephrology

authors： Harty J,Boulton H,Heelis N,Uttley L,Venning M,Gokal R

更新日期：1993-01-01 00:00:00

abstract：AIM:To develop and assess a semiautomated method for segmenting and counting individual renal cysts from mid-slice MR images in patients with autosomal dominant polycystic kidney disease (ADPKD). METHODS:A semiautomated method was developed to segment and count individual renal cysts from mid-slice MR images in 241 su...

journal_title：American journal of nephrology

authors： Bae KT,Sun H,Lee JG,Bae K,Wang J,Tao C,Chapman AB,Torres VE,Grantham JJ,Mrug M,Bennett WM,Flessner MF,Landsittel DP,Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease.

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Aldosterone plays an important role in fibrosis. Recent studies showed that Na(+)-H(+) exchanger isoform 1 (NHE1) is involved in mineralocorticoid-induced organ fibrosis. In this study, we examined the role of NHE1 in aldosterone-induced fibronectin accumulation in rat mesangial cells and the signaling pathw...

journal_title：American journal of nephrology

authors： Zhang M,Chen J,Lai L,You L,Lin S,Hao C,Gu Y

更新日期：2010-01-01 00:00:00

abstract：:In 1828, Friedrich Wöhler, a German physician and chemist by training, published a paper that describes the formation of urea, known since 1773 to be a major component of mammalian urine, by combining cyanic acid and ammonium in vitro. In these experiments the synthesis of an organic compound from two inorganic molecu...

journal_title：American journal of nephrology

authors： Kinne-Saffran E,Kinne RK

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND/AIMS:Serum phosphorus levels have been associated with adverse long-term outcome in several populations, however, no prior studies evaluated short-term postoperative outcome. The present study evaluated the predictive value of phosphorus levels on 30-day outcome after vascular surgery. METHODS:The study inc...

journal_title：American journal of nephrology

authors： van Kuijk JP,Flu WJ,Chonchol M,Valentijn TM,Verhagen HJ,Bax JJ,Poldermans D

更新日期：2010-01-01 00:00:00

abstract：:Dialysis patients have increased susceptibility to infection and this is, in part, due to impaired phagocytic and bactericidal activities of polymorphonuclear leukocytes (PMNL). The mechanisms responsible for the reduced phagocytosis are not known. Dialysis patients have elevated blood levels of parathyroid hormone (P...

journal_title：American journal of nephrology

authors： Alexiewicz JM,Smogorzewski M,Fadda GZ,Massry SG

更新日期：1991-01-01 00:00:00

abstract：:Renal disease is a common complication in malaria infection. In acute falciparum malaria renal involvement is usually mild, but in severe disease acute renal failure is a major problem. Acute renal failure has been attributed to ischaemic tubular necrosis from hypovolaemia resulting from vasodilatation due to endothel...

journal_title：American journal of nephrology

authors： Sinniah R,Lye W

更新日期：2000-07-01 00:00:00

abstract：:We report a 29-year-old female with recurrent focal glomerulosclerosis (FGS) presenting as heavy proteinuria immediately following renal transplantation. From day 13 after transplantation, daily plasma exchange was performed 6 times. Proteinuria decreased from 13 to 0.2 g/day after plasma exchange and remained to be l...

journal_title：American journal of nephrology

authors： Li PK,Lai FM,Leung CB,Lui SF,Wang A,Lai KN

更新日期：1993-01-01 00:00:00

abstract：:We assessed blood volume (BV) in 20 edematous patients with nephrotic syndrome and in 32 subjects without renal or other disease liable to induce BV variation. Two methods were chosen, one using 131I-albumin and the other 51Cr red blood cells. Among the 20 patients, 11 presented minimal-change lesions, and 9 had histo...

journal_title：American journal of nephrology

authors： Olmer M,Berland Y,Purgus R,Schultz G

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND/AIM:While the familial nature of chronic kidney disease (CKD) has been recognized, it has primarily been defined from studies of first-degree relatives of selected sets of cases. The goal of this study is an evaluation of the familial clustering of end-stage renal disease (ESRD) and CKD mortality using a pop...

journal_title：American journal of nephrology

authors： Goldfarb-Rumyantzev AS,Cheung AK,Habib AN,Wang BJ,Lin SJ,Baird BC,Naiman N,Cannon-Albright L

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Despite the significant morbidity and mortality attributable to cardiovascular disease (CVD), risk stratification remains an important challenge in the chronic kidney disease (CKD) population. We examined the discriminative ability of noninvasive measures of atherosclerosis, including carotid intima-media th...

journal_title：American journal of nephrology

authors： Adeseun GA,Xie D,Wang X,Joffe MM,Mohler ER 3rd,Townsend RR,Budoff M,Rosas SE

更新日期：2012-01-01 00:00:00

abstract：:We describe a 78-year-old patient with nephrotic syndrome due to minimal-change glomerulopathy, associated with a renal adenocarcinoma. Oliguric acute renal failure requiring hemodialysis was also observed. Surgical removal of the tumor and corticosteroid therapy resulted in resolution of the nephrotic state and impro...

journal_title：American journal of nephrology

authors： Auguet T,Lorenzo A,Colomer E,Zamora A,García C,Martínez-Vea A,Richart C,Oliver JA

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND/AIMS:Patients with chronic renal failure (CRF) secondary to diabetes mellitus show a high incidence of atherosclerosis with its thrombotic complications. Both CRF and type 2 diabetes mellitus (DM2) results in fibrinolysis defects causally related to atherogenesis and thrombogenesis. It is not well known whet...

journal_title：American journal of nephrology

authors： Opatrný K Jr,Zemanová P,Mares J,Vít L,Opatrná S,Sefrna F,Hejda V,Tomsů M,Eiselt J,Massry SG

更新日期：2002-09-01 00:00:00

abstract：:A patient with unilateral gross hematuria was found to have mesangial proliferation and IgM deposition on renal biopsy, consistent with the entity of primary renal hematuria. This case refutes previous assumptions that renal biopsy is normal in patients with unilateral hematuria. Glomerular lesions may be more common ...

journal_title：American journal of nephrology

authors： Tapp DC,Whitaker WR,Copley JB

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND/AIMS:Post-renal transplant recurrent glomerulonephritis (GN) contributes to allograft loss. Rituximab treatment has been used in a multidose strategy with variable efficacy and toxicity. We investigated a novel single-dose approach. METHODS:A single center, retrospective, cohort study was conducted between ...

journal_title：American journal of nephrology

authors： Spinner ML,Bowman LJ,Horwedel TA,Delos Santos RB,Klein CL,Brennan DC

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:The present study tested the hypothesis that chronic hypoxia adversely affects renal development in the ovine fetus. METHODS:Kidneys were collected from near-term fetuses of pregnant ewes maintained at sea level or high altitude (3,801 m, PaO(2): approx. 60 mm Hg) for 110 days (n = 6 for each group). ...

journal_title：American journal of nephrology

authors： Mao C,Hou J,Ge J,Hu Y,Ding Y,Zhou Y,Zhang H,Xu Z,Zhang L

更新日期：2010-01-01 00:00:00

abstract：AIMS:We aimed to assess humoral immune response to the influenza vaccine in adult kidney transplant recipients (KTRs) subjected to two immunosuppressive regimens containing either mycophenolate mofetil (MMF) or azathioprine (Aza). METHODS:40 eligible KTRs (24 treated with Aza [KTRs-Aza] and 16 treated with MMF [KTRs-M...

journal_title：American journal of nephrology

authors： Keshtkar-Jahromi M,Argani H,Rahnavardi M,Mirchi E,Atabak S,Tara SA,Gachkar L,Noori-Froothghe A,Mokhtari-Azad T

更新日期：2008-01-01 00:00:00

abstract：:The terminal complement-inhibitor eculizumab has dramatically changed the management of patients with atypical hemolytic uremic syndrome (aHUS), and has also shown promise for treating certain forms of secondary HUS (sHUS), including that caused by drugs and solid-organ/hematopoietic stem cell transplant. While effect...

journal_title：American journal of nephrology

authors： Olson SR,Lu E,Sulpizio E,Shatzel JJ,Rueda JF,DeLoughery TG

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The identification of nephrin and CD2AP, podocyte proteins which modulate the properties of glomerular barrier selectivity, has made it possible to unravel the mechanisms undergoing foot process effacement and proteinuria. Here we explored the role of nephrin and CD2AP together with the integrity of the slit...

journal_title：American journal of nephrology

authors： Gagliardini E,Benigni A,Tomasoni S,Abbate M,Kalluri R,Remuzzi G

更新日期：2003-07-01 00:00:00

abstract：:The development of new therapies for chronic diseases, such as diabetic kidney disease (DKD), will continue to be hampered by lack of sufficient biomarkers that will provide insights and will be responsive to treatment interventions. The recent application of metabolomic technologies, such as nuclear magnetic resonanc...

journal_title：American journal of nephrology

authors： Darshi M,Van Espen B,Sharma K

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Dietary sodium may influence cognitive function through its effects on cerebrovascular function and cerebral blood flow. METHODS:The aim of this study was to evaluate the association of dietary sodium intake with cognitive decline in community-dwelling older adults. We also evaluated the associations of die...

journal_title：American journal of nephrology

authors： Nowak KL,Fried L,Jovanovich A,Ix J,Yaffe K,You Z,Chonchol M

更新日期：2018-01-01 00:00:00

abstract：:Thymoglobulin (Thymoglobulin®; Genzyme, Cambridge, Mass., USA) is a polyclonal antibody which has been used in the field of transplantation over the last four decades. With an initial hesitancy, it is widely used now in the prevention and treatment of rejection following renal transplantation. Thymoglobulin's lack of ...

journal_title：American journal of nephrology

authors： Thiyagarajan UM,Ponnuswamy A,Bagul A

更新日期：2013-01-01 00:00:00

abstract：:Erythropoietin-stimulating agent (ESA) hyporesponsiveness is aggravated by chronic inflammation in maintenance hemodialysis (MHD) patients. Dyslipidemia is prevalent in MHD patients. Statin therapy has been demonstrated to not only be effective in lowering lipid levels, but also numerous pleiotropic effects including ...

journal_title：American journal of nephrology

authors： Chiang CK,Yang SY,Peng YS,Hsu SP,Pai MF,Huang JW,Hung KY,Wu KD

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Apolipoprotein A1 (APOL1) gene variants occurring in people of West African descent contribute to the greater burden of kidney disease among African Americans. These variants are associated with increased risk of nondiabetic nephropathy, more rapid progression of chronic kidney disease, and shorter survival ...

journal_title：American journal of nephrology

authors： Young BA,Blacksher E,Cavanaugh KL,Freedman BI,Fullerton SM,Kopp JB,Umeukeje EM,West KM,Wilson JG,Burke W,APOL1 Stakeholders Project.

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Hepcidin synthesis in hepatocytes is modulated in response to anemia, hypoxia or inflammation. A cross-sectional study was performed to assess hepcidin correlations with markers of iron status, erythropoietin therapy and markers of inflammation in hemodialyzed patients and in the healthy volunteers. METHODS...

journal_title：American journal of nephrology

authors： Małyszko J,Małyszko JS,Hryszko T,Pawlak K,Mysliwiec M

更新日期：2005-11-01 00:00:00

abstract：:Renal function and life expectancy can be improved by aggressive antihypertensive therapy in severe hypertension. However, most reports of severe hypertension and renal failure concern primary hypertensive states. 3 cases of primary renal disease, 1 glomerular, 1 obstructive and 1 of chronic pyelonephritis, are descri...

journal_title：American journal of nephrology

authors： Friedlaender MM,Rubinger D,Popovtzer MM

更新日期：1982-01-01 00:00:00