A patient with thrombotic microangiopathy accompanied by glomerular subendothelial electron dense deposits.

abstract：BACKGROUND:Evidence suggests that recombinant human erythropoietin (rHuEPO) protects neurons and cardiomyocytes from acute insults. We investigated the protective effect of rHuEPO on cyclosporine (CsA)-induced renal injury. METHODS:CsA (15 mg/kg/day) was given to rats for 1 or 4 weeks, and rHuEPO was concurrently admi...

journal_title：American journal of nephrology

authors： Lee SH,Li C,Lim SW,Ahn KO,Choi BS,Kim YS,Moon IS,Kim J,Bang BK,Yang CW

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Vascular calcification is seen in most patients on dialysis and is strongly associated with cardiovascular mortality. Vascular calcification is promoted by phosphate, which generally reaches higher levels in hemodialysis than in peritoneal dialysis. However, whether vascular calcification develops less in pe...

journal_title：American journal of nephrology

authors： Jansz TT,van Reekum FE,Özyilmaz A,de Jong PA,Boereboom FTJ,Hoekstra T,Verhaar MC,van Jaarsveld BC

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Predicting the mortality risk of patients un-dergoing hemodialysis (HD) is challenging. Cell-free DNA (cfDNA) is released into circulation from dying cells, and its elevation is predictive of unfavorable outcome. In a pilot study, we found post-HD cfDNA level to be a predictor of all-cause mortality. Thus, t...

journal_title：American journal of nephrology

authors： Einbinder Y,Shnaider A,Ghanayem K,Basok A,Rogachev B,Lior Y,Haviv YS,Cohen-Hagai K,Nacasch N,Rozenberg I,Benchetrit S,Zitman-Gal T,Douvdevani A

更新日期：2020-01-01 00:00:00

abstract：:The current study focused on the effect of continuous ambulatory peritoneal dialysis (CAPD) dialysate obtained following different intraperitoneal dwell periods on the release of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF alpha) from mononuclear leukocytes (PBMC). Aliquots of 5 x 10(6)/ml healthy periph...

journal_title：American journal of nephrology

authors： Jörres A,Topley N,Steenweg L,Müller C,Köttgen E,Gahl GM

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:The use of complementary/alternative medicine has garnered rising interest in recent years. Natural products including herbs, vitamins, and minerals are the most popularly consumed. The Internet is a ubiquitous source of information/market for these supplements. AIM:To systematically evaluate the dietary an...

journal_title：American journal of nephrology

authors： Vamenta-Morris H,Dreisbach A,Shoemaker-Moyle M,Abdel-Rahman EM

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:While chronic dialysis treatment has been suggested to increase pulmonary pressure values, right ventricular dysfunction (RVD) is a major cause of death in patients with end-stage renal disease. We investigated the impact of different dialysis treatments on right ventricular function. METHODS:We examined 22...

journal_title：American journal of nephrology

authors： Paneni F,Gregori M,Ciavarella GM,Sciarretta S,De Biase L,Marino L,Tocci G,Principe F,Domenici A,Luciani R,Punzo G,Menè P,Volpe M

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Persons with chronic kidney disease (CKD) represent a population prone to cardiovascular disease (CVD) but vulnerable to adverse medication effects. We assessed the impact of intensive antihypertensive therapy on the cerebrovascular and other CVD outcomes in high-risk patients with type 2 diabetes and baseli...

journal_title：American journal of nephrology

authors： Papademetriou V,Zaheer M,Doumas M,Lovato L,Applegate WB,Tsioufis C,Mottle A,Punthakee Z,Cushman WC,ACCORD Study Group.

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:Pseudotumors of the craniovertebral junction (PTCVJ) are observed in long-term hemodialysis (HD) patients. There are neither criteria for diagnosis nor guidelines for screening. We attempted to determine magnetic resonance imaging (MRI) findings that could be used to detect PTCVJ, to determine the preva...

journal_title：American journal of nephrology

authors： Maruyama H,Tanizawa T,Uchiyama S,Higuchi T,Ei K,Oda M,Ei I,Oya M,Kishimoto H,Saito T,Miyamura S,Takano Y,Hasegawa S,Kawada K,Ueki K,Iwafuchi Y,Arakawa M

更新日期：1999-01-01 00:00:00

abstract：:Therapeutic use of D-penicillamine has been associated with a range of adverse effects. We present a patient with scleroderma, treated with D-penicillamine for 5 years, who developed severe renal failure due to rapidly progressive glomerulonephritis with both crescents and subepithelial immune deposits on renal biopsy...

journal_title：American journal of nephrology

authors： Karpinski J,Jothy S,Radoux V,Levy M,Baran D

更新日期：1997-01-01 00:00:00

abstract：:Hyperlipidemia is common in patients with glomerular proteinuria. It may contribute to atherosclerotic complications and accelerate glomerular damage. Early trials of the fibric acid derivative clofibrate led to a myositis syndrome causing many nephrologists to abandon attempts at treatment of nephrotic hyperlipidemia...

journal_title：American journal of nephrology

authors： Appel GB,Appel AS

更新日期：1990-01-01 00:00:00

abstract：:Collapsing glomerulopathy is a pattern of renal injury that is seen in association with human immunodeficiency virus (HIV) infection. Patients with this HIV-associated nephropathy (HIVAN) present nephrotic syndrome and rapid deterioration of the renal function. There is no proven effective therapy for HIVAN, and the m...

journal_title：American journal of nephrology

authors： Morales E,Martinez A,Sánchez-Ayuso J,Gutierrez E,Mateo S,Martínez MA,Herrero JC,Praga M

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:The proinflammatory cytokine S100A12 (also known as EN-RAGE) is associated with cardiovascular morbidity and mortality in hemodialysis patients. In the current study, we tested the hypothesis that S100A12 expressed in vascular smooth muscle in nonatherosclerosis-prone C57BL/6J mice on normal rodent chow diet...

journal_title：American journal of nephrology

authors： Gawdzik J,Mathew L,Kim G,Puri TS,Hofmann Bowman MA

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND/AIMS:Intradialytic hypotension is the most common complication of modern day haemodialysis (HD). Convective modalities, including haemodiafiltration (HDF) are reported to result in greater cardiovascular stability compared to standard HD, which has been suggested to be due to improved solute transport betwee...

journal_title：American journal of nephrology

authors： Kumar S,Khosravi M,Massart A,Potluri M,Davenport A

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND/AIMS:Post-renal transplant recurrent glomerulonephritis (GN) contributes to allograft loss. Rituximab treatment has been used in a multidose strategy with variable efficacy and toxicity. We investigated a novel single-dose approach. METHODS:A single center, retrospective, cohort study was conducted between ...

journal_title：American journal of nephrology

authors： Spinner ML,Bowman LJ,Horwedel TA,Delos Santos RB,Klein CL,Brennan DC

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:There is a higher risk of gastrointestinal (GI) bleeding in patients treated with dabigatran versus warfarin. We analyzed the impact of renal function on the relative risk of bleeding in patients converted to dabigatran. METHODS:Patients aged ≥65 years who received anticoagulation with warfarin for a minimu...

journal_title：American journal of nephrology

authors： Kalil RS,Kaboli PJ,Liu X,Vaughan-Sarrazin M

更新日期：2016-01-01 00:00:00

abstract：:Hemolytic-uremic syndrome following quinine ingestion is a newly described phenomenon, with just two previous descriptions of 4 cases in the literature. We describe a 5th case. The reaction may be mediated by the presence of antibodies reactive against platelets in the presence of quinine. Treatment has included use o...

journal_title：American journal of nephrology

authors： Hagley MT,Hosney IA,Hulisz DT,Davis HH

更新日期：1992-01-01 00:00:00

abstract：:Chronic kidney disease affects approximately 10% of the world's adult population: it is within the top 20 causes of death worldwide, and its impact on patients and their families can be devastating. World Kidney Day and International Women's Day in 2018 coincide, thus offering an opportunity to reflect on the importan...

journal_title：American journal of nephrology

authors： Piccoli GB,Alrukhaimi M,Liu ZH,Zakharova E,Levin A,World Kidney Day Steering Committee.

更新日期：2018-01-01 00:00:00

abstract：:A 22-year-old woman presented glomerulonephritis with Schönlein-Henoch-like syndrome and monoclonal abnormality. One month later, she developed a rapidly progressive glomerulonephritis with hypertension and persistent purpura. In the two renal biopsies performed during the first and the second attack, mesangial expans...

journal_title：American journal of nephrology

authors： Orfila C,Meeus F,Bernadet P,Lepert JC,Suc JM

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Patients with chronic kidney disease (CKD) show increased cardiovascular morbidity. We hypothesized that vascular properties which can be routinely evaluated noninvasively are related to different stages of CKD and their clinical and biochemical characteristics. METHODS:Arterial vascular properties were qua...

journal_title：American journal of nephrology

authors： Tetzner F,Scholze A,Wittstock A,Zidek W,Tepel M

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Malnutrition-inflammation score (MIS) is a comprehensive and quantitative system to assess malnutrition-inflammation complex syndrome, and a strong correlation between MIS and morbidity/mortality in maintenance hemodialysis (MHD) patients had been demonstrated. However, there is no cut-off value of MIS to ca...

journal_title：American journal of nephrology

authors： Ho LC,Wang HH,Peng YS,Chiang CK,Huang JW,Hung KY,Hu FC,Wu KD

更新日期：2008-01-01 00:00:00

abstract：:A quantitative scoring method was designed to assess the extent of muscle damage. Technetium-99m pyrophosphate (99mTc-PYP) scintigraphy was performed for 9 patients experiencing crush injury in the Chichi (Taiwan) earthquake. The magnitude of muscle uptake of 99mTc-PYP was graded as follows: grade 0, less than bone ra...

journal_title：American journal of nephrology

authors： Chang HR,Kao CH,Lian JD,Shu KH,Cheng CH,Wu MJ,Chen CH

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Hyperkalemia is common in patients receiving maintenance hemodialysis. However, few studies have examined the association between serum potassium level and mortality. METHODS:This study used annual cohorts of hemodialysis patients during 2007-2010. To determine hyperkalemia prevalence, monthly hyperkalemia ...

journal_title：American journal of nephrology

authors： Yusuf AA,Hu Y,Singh B,Menoyo JA,Wetmore JB

更新日期：2016-01-01 00:00:00

abstract：:This study investigated the possible beneficial effect of intraperitoneal proteolytic enzyme administration on the development of hypertension-induced renal injury in the rat model of 2-kidney 1-clip (2K1C) Goldblatt hypertension. Male Wistar rats (120-150 g) underwent either sham surgery (control, n = 5) or clipping ...

journal_title：American journal of nephrology

authors： Sebeková K,Dämmrich J,Fierlbeck W,Krivosiková Z,Paczek L,Heidland A

更新日期：1998-01-01 00:00:00

abstract：:Nutrition has been shown to predict clinical outcome in continuous ambulatory peritoneal dialysis (CAPD) patients. However, despite the positive relationship between KT/V (urea) and the normalised protein catabolic rate, the ability of urea kinetic modelling to predict clinical outcome or nutrition remains inconclusiv...

journal_title：American journal of nephrology

authors： Harty J,Boulton H,Heelis N,Uttley L,Venning M,Gokal R

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:End-stage renal disease (ESRD) is a disease with an aging population and a high prevalence of cognitive impairment affecting quality of life, health care costs and mortality. Structural changes in the brain with decreased white matter integrity have been observed in ESRD. Understanding the changes in cogniti...

journal_title：American journal of nephrology

authors： Gupta A,Lepping RJ,Yu AS,Perea RD,Honea RA,Johnson DK,Brooks WM,Burns JM

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:Although the effect of exercise on health is well established, nephrologists seldom consider physical activity in the treatment of chronic kidney disease (CKD) or CKD in the presence of diabetes mellitus (DM/CKD). The aim of the present study was to analyze the benefits of leisure-time physical activity...

journal_title：American journal of nephrology

authors： Wang IK,Tsai MK,Liang CC,Yen TH,Huang CC,Wen SF,Wen CP

更新日期：2013-01-01 00:00:00

abstract：:We have recently described that in the erythrocytes from uremic patients on chronic hemodialysis, the pentose-phosphate shunt is defective, the membrane concentrations of malonyldialdehyde, resulting from peroxidation of polyunsaturated fatty acids in the membranes themselves, are increased, and the concentrations of ...

journal_title：American journal of nephrology

authors： Taccone-Gallucci M,Giardini O,Lubrano R,Mazzarella V,Bandino D,Khashan S,Mannarino O,Elli M,Cozzari M,Buoncristiani U

更新日期：1986-01-01 00:00:00

abstract：:Thirty-one renal transplant recipients, submitted to treatment with cyclosporin in association with other immunosuppressive agents, were also treated for 9 months with two hydroxymethylglutaryl coenzyme A reductase inhibitors, simvastatin (10 mg/day) or pravastatin (20 mg/day), for concomitant hypercholesterolemia and...

journal_title：American journal of nephrology

authors： Capone D,Stanziale P,Gentile A,Imperatore P,Pellegrino T,Basile V

更新日期：1999-01-01 00:00:00

abstract：:Shortage of kidney donor is still a major limitation for renal transplantation programs. This review focuses on the emerging practices, adopted to increase transplant activities, of expanding the criteria for donor and recipient selection without exposing the recipient to the drawbacks of a graft with inadequate nephr...

journal_title：American journal of nephrology

authors： Perico N,Ruggenenti P,Scalamogna M,Remuzzi G

更新日期：2003-07-01 00:00:00

abstract：:The number of patients with end-stage renal disease undergoing kidney transplantation - both cadaveric and living-donor - continues to rise. With long-term graft survival relatively fixed, this trend means that increasing numbers of patients are returning to dialysis after graft loss. Most will never be retransplanted...

journal_title：American journal of nephrology

authors： Fuquay R,Teitelbaum I

更新日期：2012-01-01 00:00:00