Effect of first and subsequent use of hemodialyzers on patient well-being. Analysis of the incidence of symptoms and events and description of a syndrome associated with new dialyzer use.

abstract：BACKGROUND:Obesity is an independent risk factor for morbidity and mortality in cardiovascular diseases not only in the general population, but also in hemodialysis (HD) patients. We previously reported that an increased visceral fat area (VFA) determined using computed tomography (CT) scans was associated with atheros...

journal_title：American journal of nephrology

authors： Okamoto T,Morimoto S,Ikenoue T,Furumatsu Y,Ichihara A

更新日期：2014-01-01 00:00:00

abstract：:Hyperlipidemia is common in patients with glomerular proteinuria. It may contribute to atherosclerotic complications and accelerate glomerular damage. Early trials of the fibric acid derivative clofibrate led to a myositis syndrome causing many nephrologists to abandon attempts at treatment of nephrotic hyperlipidemia...

journal_title：American journal of nephrology

authors： Appel GB,Appel AS

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Tacrolimus has been reported to be effective in refractory nephrotic syndrome, such as focal segmental glomerulosclerosis and membranous nephropathy. Some IgA nephropathy (IgAN) patients with massive proteinuria showed resistance to steroids and/or cytotoxic immunosuppressants based on the supportive therapy...

journal_title：American journal of nephrology

authors： Zhang Q,Shi SF,Zhu L,Lv JC,Liu LJ,Chen YQ,Zhang H,Wang HY

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:There has been an increasing incidence of hemodialysis (HD) due to old age and comorbid condition such as diabetes. In general, socioeconomic status (SES) is known as one of the most important risk factors for patient mortality and morbidity. Whether low SES is associated with poorer outcome in HD patients i...

journal_title：American journal of nephrology

authors： Park HC,Kwon YE,Choi HY,Oh HJ,Chang TI,Kang EW,Park KS,Yang KH,Won EM,Shin JH,Ryu DR,Lee YK

更新日期：2021-01-13 00:00:00

abstract：BACKGROUND:Predicting the mortality risk of patients un-dergoing hemodialysis (HD) is challenging. Cell-free DNA (cfDNA) is released into circulation from dying cells, and its elevation is predictive of unfavorable outcome. In a pilot study, we found post-HD cfDNA level to be a predictor of all-cause mortality. Thus, t...

journal_title：American journal of nephrology

authors： Einbinder Y,Shnaider A,Ghanayem K,Basok A,Rogachev B,Lior Y,Haviv YS,Cohen-Hagai K,Nacasch N,Rozenberg I,Benchetrit S,Zitman-Gal T,Douvdevani A

更新日期：2020-01-01 00:00:00

abstract：:The treatment of peritonitis in continuous ambulatory peritoneal dialysis patients is empiric until the bacteriological results are available. The Lymulus amebocyte lysate assay (LAL) is a very sensitive method for the detection of endotoxin, a structural component of gram-negative bacteria. We performed the LAL assay...

journal_title：American journal of nephrology

authors： Peer G,Serban I,Blum M,Cabili S,Iaina A

更新日期：1992-01-01 00:00:00

abstract：:The acid-base balance of 199 patients with cystic fibrosis, seen from 1987 through 1992 at the Bern Outpatient Clinic, were evaluated. Simple metabolic alkalosis was demonstrated in 16 and mixed metabolic alkalosis and respiratory acidosis in 9 patients. When compared with 10 patients with simple respiratory acidosis ...

journal_title：American journal of nephrology

authors： Pedroli G,Liechti-Gallati S,Mauri S,Birrer P,Kraemer R,Foletti-Jäggi C,Bianchetti MG

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Vascular calcification is seen in most patients on dialysis and is strongly associated with cardiovascular mortality. Vascular calcification is promoted by phosphate, which generally reaches higher levels in hemodialysis than in peritoneal dialysis. However, whether vascular calcification develops less in pe...

journal_title：American journal of nephrology

authors： Jansz TT,van Reekum FE,Özyilmaz A,de Jong PA,Boereboom FTJ,Hoekstra T,Verhaar MC,van Jaarsveld BC

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Hepcidin synthesis in hepatocytes is modulated in response to anemia, hypoxia or inflammation. A cross-sectional study was performed to assess hepcidin correlations with markers of iron status, erythropoietin therapy and markers of inflammation in hemodialyzed patients and in the healthy volunteers. METHODS...

journal_title：American journal of nephrology

authors： Małyszko J,Małyszko JS,Hryszko T,Pawlak K,Mysliwiec M

更新日期：2005-11-01 00:00:00

abstract：:This study was designed to evaluate beta-adrenergic responsiveness as assessed by the generation of cyclic AMP after the subcutaneous administration of epinephrine in 31 subjects: normal controls, patients with chronic renal insufficiency, hemodynamically stable patients on chronic acetate dialysis and hemodynamically...

journal_title：American journal of nephrology

authors： Fuiano G,Dal Canton A,Maj M,Testa A,Memoli B,Conte G,Ariano MG,Guarriello L,Russo D,Andreucci VE

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:The impact of socioeconomic factors on arteriovenous fistula (AVF) creation in hemodialysis (HD) patients is not well understood. We assessed the association of area and individual-level indicators of poverty and health care insurance on AVF use among incident end-stage renal disease (ESRD) patients initiate...

journal_title：American journal of nephrology

authors： Nee R,Moon DS,Jindal RM,Hurst FP,Yuan CM,Agodoa LY,Abbott KC

更新日期：2015-01-01 00:00:00

abstract：:The effects of cisplatin (5 mg/kg BW given intraperitoneally) on renal concentration mechanism were evaluated initially by clearance studies in rats 5-7 days after cisplatin administration and compared to normal rats. During hypotonic saline infusion, cisplatin rats showed a lower inulin clearance (0.56 +/- 0.07 vs. 1...

journal_title：American journal of nephrology

authors： Seguro AC,Shimizu MH,Kudo LH,dos Santos Rocha A

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND/AIMS:Advanced glycation end products (AGEs) induce epithelial mesenchymal transition (EMT) in renal proximal tubular epithelial cells (PTECs) by promoting the two EMT regulators, transforming growth factor beta (TGF-β) and connective tissue growth factor (CTGF). However, the exact signaling mechanism remains...

journal_title：American journal of nephrology

authors： Cheng M,Liu H,Zhang D,Liu Y,Wang C,Liu F,Chen J

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Tacrolimus is mainly metabolized by cytochrome P450 3A5 (CYP3A5), which is expressed in the liver. However, CYP3A5 is also expressed in the kidney tissue and may contribute to local tacrolimus clearance in the kidney allograft. We aimed to evaluate the association between the allograft CYP3A5 genotype and tr...

journal_title：American journal of nephrology

authors： Udomkarnjananun S,Townamchai N,Chariyavilaskul P,Iampenkhae K,Pongpirul K,Sirichindakul B,Panumatrassamee K,Vanichanan J,Avihingsanon Y,Eiam-Ong S,Praditpornsilpa K

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND/AIMS:The value of neutrophil-gelatinase-associated lipocalin (NGAL), a novel biomarker in the detection of acute renal failure in children after cardiac surgery, has been highlighted in previous studies. The incidence of percutaneous coronary intervention (PCI) increases, which may possibly result in increas...

journal_title：American journal of nephrology

authors： Bachorzewska-Gajewska H,Malyszko J,Sitniewska E,Malyszko JS,Dobrzycki S

更新日期：2006-01-01 00:00:00

abstract：:In 1828, Friedrich Wöhler, a German physician and chemist by training, published a paper that describes the formation of urea, known since 1773 to be a major component of mammalian urine, by combining cyanic acid and ammonium in vitro. In these experiments the synthesis of an organic compound from two inorganic molecu...

journal_title：American journal of nephrology

authors： Kinne-Saffran E,Kinne RK

更新日期：1999-01-01 00:00:00

abstract：:The development of new therapies for chronic diseases, such as diabetic kidney disease (DKD), will continue to be hampered by lack of sufficient biomarkers that will provide insights and will be responsive to treatment interventions. The recent application of metabolomic technologies, such as nuclear magnetic resonanc...

journal_title：American journal of nephrology

authors： Darshi M,Van Espen B,Sharma K

更新日期：2016-01-01 00:00:00

abstract：:45 bone biopsies from patients with chronic uremia were reviewed to define which noninvasive investigations were of value in predicting the histological diagnosis and to quantify the spectrum of uremic bone disease at a center that has consistently used an aluminum-free dialysis bath. 17 biopsies were taken postmortem...

journal_title：American journal of nephrology

authors： Heaf JG,Joffe P,Pødenphant J,Andersen JR

更新日期：1987-01-01 00:00:00

abstract：:Thirty-one renal transplant recipients, submitted to treatment with cyclosporin in association with other immunosuppressive agents, were also treated for 9 months with two hydroxymethylglutaryl coenzyme A reductase inhibitors, simvastatin (10 mg/day) or pravastatin (20 mg/day), for concomitant hypercholesterolemia and...

journal_title：American journal of nephrology

authors： Capone D,Stanziale P,Gentile A,Imperatore P,Pellegrino T,Basile V

更新日期：1999-01-01 00:00:00

abstract：:A dramatic response was noted in a patient at our hospital who received hemodialysis therapy for severe acidosis secondary to an unknown toxin, subsequently identified as cyanide. We were unable to find any information concerning the hemodialysis clearance and extraction ratio of cyanide; thus, we studied the effect o...

journal_title：American journal of nephrology

authors： Wesson DE,Foley R,Sabatini S,Wharton J,Kapusnik J,Kurtzman NA

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND/AIMS:There is evidence that hereditary predisposition contributes to the development of diabetic nephropathy and hypertension. Polymorphisms in the genes for bradykinin receptors (B(1)R and B(2)R) were found to be associated with decreased risk of the development of end-stage renal disease. This study examin...

journal_title：American journal of nephrology

authors： Zychma MJ,Gumprecht J,Trautsolt W,Szydlowska I,Grzeszczak W

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Various medications are cleared by the kidneys, therefore patients with impaired renal function, especially dialysis patients are at risk for adverse drug events (ADEs). There are limited studies on ADEs in maintenance dialysis patients. METHODS:We utilized a nationally representative database, the Nationwi...

journal_title：American journal of nephrology

authors： Chan L,Saha A,Poojary P,Chauhan K,Naik N,Coca S,Garimella PS,Nadkarni GN

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Patients with chronic kidney disease (CKD) show increased cardiovascular morbidity. We hypothesized that vascular properties which can be routinely evaluated noninvasively are related to different stages of CKD and their clinical and biochemical characteristics. METHODS:Arterial vascular properties were qua...

journal_title：American journal of nephrology

authors： Tetzner F,Scholze A,Wittstock A,Zidek W,Tepel M

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Inflammation and increased erythropoiesis stimulating agents (ESA) requirement are frequently associated in patients on dialysis. On-line hemodiafiltration (ol-HDF), putting together high levels of diffusion, and convection could improve both conditions. However, it is still not known which depurative compon...

journal_title：American journal of nephrology

authors： Movilli E,Camerini C,Gaggia P,Zubani R,Feller P,Salviani C,Facchini A,Cancarini G

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Almost 20 million people in the US have chronic kidney disease (CKD). Cardiovascular disease and arterial wall abnormalities are common in this population. Because angiotensin II may have adverse effects on the arterial wall, we hypothesized that an angiotensin receptor blocker (ARB) would improve arterial c...

journal_title：American journal of nephrology

authors： Garg JP,Ellis R,Elliott WJ,Hasabou N,Chua D,Chertow GM,Bakris GL

更新日期：2005-07-01 00:00:00

abstract：:A quantitative scoring method was designed to assess the extent of muscle damage. Technetium-99m pyrophosphate (99mTc-PYP) scintigraphy was performed for 9 patients experiencing crush injury in the Chichi (Taiwan) earthquake. The magnitude of muscle uptake of 99mTc-PYP was graded as follows: grade 0, less than bone ra...

journal_title：American journal of nephrology

authors： Chang HR,Kao CH,Lian JD,Shu KH,Cheng CH,Wu MJ,Chen CH

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Persons with chronic kidney disease (CKD) represent a population prone to cardiovascular disease (CVD) but vulnerable to adverse medication effects. We assessed the impact of intensive antihypertensive therapy on the cerebrovascular and other CVD outcomes in high-risk patients with type 2 diabetes and baseli...

journal_title：American journal of nephrology

authors： Papademetriou V,Zaheer M,Doumas M,Lovato L,Applegate WB,Tsioufis C,Mottle A,Punthakee Z,Cushman WC,ACCORD Study Group.

更新日期：2016-01-01 00:00:00

abstract：:Chronic kidney disease affects approximately 10% of the world's adult population: it is within the top 20 causes of death worldwide, and its impact on patients and their families can be devastating. World Kidney Day and International Women's Day in 2018 coincide, thus offering an opportunity to reflect on the importan...

journal_title：American journal of nephrology

authors： Piccoli GB,Alrukhaimi M,Liu ZH,Zakharova E,Levin A,World Kidney Day Steering Committee.

更新日期：2018-01-01 00:00:00

abstract：:Alcaligenes xylosoxidans is an uncommon cause of peritonitis in patients on maintenance continuous ambulatory peritoneal dialysis (CAPD). Peritonitis caused by A. xylosoxidans usually carries a poor prognosis because of the pathogen's virulence and its universal resistance to most antimicrobial agents. Even after earl...

journal_title：American journal of nephrology

authors： Tang S,Cheng CC,Tse KC,Li FK,Choy BY,Chan TM,Lai KN

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:A poor nutritional state is associated with an increased risk of cardiovascular events in end-stage renal disease. It is unclear whether malnutrition itself can induce cardiovascular disease (CVD). We examined the impact of nutritional status on patients' arterial stiffness in peritoneal dialysis (PD) patien...

journal_title：American journal of nephrology

authors： Tang W,Cheng LT,Lu XH,Wang T

更新日期：2009-01-01 00:00:00