Effects of simvastatin and pravastatin on hyperlipidemia and cyclosporin blood levels in renal transplant recipients.

abstract：:We retrospectively reviewed the course of 1,000 renal transplants performed in 835 recipients (758 nondiabetics) to assess the incidence of new onset posttransplant diabetes in former nondiabetics. A total of 119 (15.7%) recipients manifested posttransplant diabetes, of whom 64 (53.8%) became hyperglycemic within 3 we...

journal_title：American journal of nephrology

authors： Friedman EA,Shyh TP,Beyer MM,Manis T,Butt KM

更新日期：1985-01-01 00:00:00

abstract：:Tuberculosis associated with dialysis was studied at the Artificial Kidney Unit (AKU) in Abha, Saudi Arabia. There were 13 tuberculosis patients out of 270 patients on maintenance hemodialysis from August 1986 to July 1993, a prevalence of 4.8%. Ten (77%) were female and 3 (23%) were male, mean age of 51.23 +/- 11.62 ...

journal_title：American journal of nephrology

authors： al-Homrany M

更新日期：1997-01-01 00:00:00

abstract：:In 1828, Friedrich Wöhler, a German physician and chemist by training, published a paper that describes the formation of urea, known since 1773 to be a major component of mammalian urine, by combining cyanic acid and ammonium in vitro. In these experiments the synthesis of an organic compound from two inorganic molecu...

journal_title：American journal of nephrology

authors： Kinne-Saffran E,Kinne RK

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Although rhabdomyolysis has been associated with acute kidney injury and mortality in the short term, the long-term consequences of an episode of rhabdomyolysis remain unknown. We sought to identify the long-term outcomes of rhabdomyolysis, including mortality, renal function, and incidence of hypertension (...

journal_title：American journal of nephrology

authors： Faulk T,Walker LE,Howard JT,Janak JC,Sosnov JA,Stewart IJ

更新日期：2018-01-01 00:00:00

abstract：:Bacterial endocarditis, particularly involving the left side, has been shown to occur in patients in regular hemodialysis. We report a case of right-sided endocarditis characterized by a very torpid evolution. Although the diagnosis was suspected early in the course, confirmation was obtained 2 months after the onset....

journal_title：American journal of nephrology

authors： Ferrer C,Jakob E,Pastorino G,Juncos LI

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Tacrolimus has been reported to be effective in refractory nephrotic syndrome, such as focal segmental glomerulosclerosis and membranous nephropathy. Some IgA nephropathy (IgAN) patients with massive proteinuria showed resistance to steroids and/or cytotoxic immunosuppressants based on the supportive therapy...

journal_title：American journal of nephrology

authors： Zhang Q,Shi SF,Zhu L,Lv JC,Liu LJ,Chen YQ,Zhang H,Wang HY

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:Although the effect of exercise on health is well established, nephrologists seldom consider physical activity in the treatment of chronic kidney disease (CKD) or CKD in the presence of diabetes mellitus (DM/CKD). The aim of the present study was to analyze the benefits of leisure-time physical activity...

journal_title：American journal of nephrology

authors： Wang IK,Tsai MK,Liang CC,Yen TH,Huang CC,Wen SF,Wen CP

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Hypercholesterolemia is one of the major manifestations of nephrotic syndrome. We have previously shown that nephrotic hypercholesterolemia is associated with and, in part, due to dysregulation of hepatic HMG-CoA reductase, acyl-CoA:cholesterol acyltransferase (ACAT) and cholesterol 7alpha-hydroxylase, as we...

journal_title：American journal of nephrology

authors： Vaziri ND,Liang K

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:We determined the familial aggregation of end-stage renal disease (ESRD) in a large, population-based sample of incident ESRD cases to assess the feasibility of developing a targeted screening and prevention program directed at members of families at high risk for kidney disease. METHODS:Between January 1, ...

journal_title：American journal of nephrology

authors： Freedman BI,Volkova NV,Satko SG,Krisher J,Jurkovitz C,Soucie JM,McClellan WM

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Transplant glomerulopathy (TG) represents a major cause of long-term allograft failure and is the leading cause of overall post-transplant proteinuria. The extent to which histopathologic features predicts prognostication is uncertain. METHODS:A single-center retrospective cohort with biopsy-proven TG was i...

journal_title：American journal of nephrology

authors： Li X,Chen J,Cheng D,Wang W,Xie K,Zhang M,Xu F,Wen J,Tang Z

更新日期：2019-01-01 00:00:00

abstract：:Heavy proteinuria in patients with essential hypertension raises the question of underlying primary renal disease. While malignant hypertension may be associated with proteinuria in the nephrotic range, it is generally held that protein excretion in benign nephrosclerosis is almost invariably less than 0.5-1.0 g/24 h....

journal_title：American journal of nephrology

authors： Mujais SK,Emmanouel DS,Kasinath BS,Spargo BH

更新日期：1985-01-01 00:00:00

abstract：:A national sample of dialysis physicians was used to obtain data for a comparison of patient characteristics, comorbid conditions and treatment patterns associated with the five leading causes of end-stage renal disease (ESRD). The data are used to assess trends in physician care for ESRD patients and likely changes i...

journal_title：American journal of nephrology

authors： Radecki SE,Nissenson AR

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Medullary sponge kidney (MSK) is characterized by malformation of the terminal collecting ducts and is associated with an increased risk of nephrolithiasis, nephrocalcinosis, urinary tract infections, renal acidification defects, and reduced bone density. It has been historically diagnosed with intravenous p...

journal_title：American journal of nephrology

authors： Koraishy FM,Ngo TT,Israel GM,Dahl NK

更新日期：2014-01-01 00:00:00

abstract：:Renal disease is a common complication in malaria infection. In acute falciparum malaria renal involvement is usually mild, but in severe disease acute renal failure is a major problem. Acute renal failure has been attributed to ischaemic tubular necrosis from hypovolaemia resulting from vasodilatation due to endothel...

journal_title：American journal of nephrology

authors： Sinniah R,Lye W

更新日期：2000-07-01 00:00:00

abstract：:Since it was first discovered in the early 1980s, the role of atrial natriuretic peptide (ANP) in the control of fluid and electrolyte balance and blood pressure has been extensively studied in both health and disease. We report here a study of ANP and its relationship to corresponding changes in right atrial pressure...

journal_title：American journal of nephrology

authors： Tan SY,Nolan J,Craig K,Swainson CP

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Uric acid has been reported to be a risk factor for the development of chronic kidney disease; however, no study has examined whether uric acid may confer a risk for acute kidney injury. METHODS:We investigated the relation between serum uric acid and the incidence of postoperative acute kidney injury in pa...

journal_title：American journal of nephrology

authors： Ejaz AA,Beaver TM,Shimada M,Sood P,Lingegowda V,Schold JD,Kim T,Johnson RJ

更新日期：2009-01-01 00:00:00

abstract：:The platelet content of adenosine triphosphate (ATP), adenosine diphosphate (ADP), serotonin and ouabain-insensitive, magnesium-dependent adenosine triphosphatase (ATPase) was determined in patients with chronic renal failure, patients on chronic hemodialysis, and kidney transplant recipients. Platelet ATP content was...

journal_title：American journal of nephrology

authors： Eknoyan G,Brown CH 3rd

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:African Americans (AAs) suffer the widest gaps in chronic kidney disease (CKD) outcomes compared to Caucasian Americans (CAs) and this is because of the disparities that exist in both health and healthcare. In fact, the prevalence of CKD is 3.5 times higher in AAs compared to CAs. The disparities exist at al...

journal_title：American journal of nephrology

authors： Harding K,Mersha TB,Vassalotti JA,Webb FA,Nicholas SB

更新日期：2017-01-01 00:00:00

abstract：AIM:The relation of ambient temperature (AMT) and relative humidity to systolic blood pressure (SBP), diastolic blood pressure (DBP), body weight (BW), and body weight gain between dialysis sessions (DeltaBW) was examined in hemodialysis patients by Fourier analysis. METHODS AND RESULTS:The authors recruited 144 dialy...

journal_title：American journal of nephrology

authors： Tozawa M,Iseki K,Iseki C,Morita O,Yoshi S,Fukiyama K

更新日期：1999-01-01 00:00:00

abstract：:A meeting on the History of Nephrology is an opportunity to discuss the links between science and faith which were split until the 6th century. However, this was changed by Cassiodorus and monasticism. From the times of Abbot Bertario (died 883 AD) in Montecassino, medicine was regarded as an art and a science. Codex ...

journal_title：American journal of nephrology

authors： D'Onorio B

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND/AIMS:Intravenous (IV) iron preparations are widely used in the management of anemia in ESRD populations. Recent changes in reimbursement policy have dramatically increased the use of IV iron to lower the use of costly erythropoiesis-stimulating agents. These preparations are frequently administered with insu...

journal_title：American journal of nephrology

authors： Kamanna VS,Ganji SH,Shelkovnikov S,Norris K,Vaziri ND

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Vascular calcification is seen in most patients on dialysis and is strongly associated with cardiovascular mortality. Vascular calcification is promoted by phosphate, which generally reaches higher levels in hemodialysis than in peritoneal dialysis. However, whether vascular calcification develops less in pe...

journal_title：American journal of nephrology

authors： Jansz TT,van Reekum FE,Özyilmaz A,de Jong PA,Boereboom FTJ,Hoekstra T,Verhaar MC,van Jaarsveld BC

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:There is a higher risk of gastrointestinal (GI) bleeding in patients treated with dabigatran versus warfarin. We analyzed the impact of renal function on the relative risk of bleeding in patients converted to dabigatran. METHODS:Patients aged ≥65 years who received anticoagulation with warfarin for a minimu...

journal_title：American journal of nephrology

authors： Kalil RS,Kaboli PJ,Liu X,Vaughan-Sarrazin M

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Protein-energy wasting (PEW) is common and associated with poor outcome in hemodialysis patients. In hemodialysis patients, geriatric nutritional risk index (GNRI) and decoy receptor 3 (DcR3) have been shown as the nutritional and inflammatory markers, respectively. The present study aimed to assess the pred...

journal_title：American journal of nephrology

authors： Tsai MT,Hu FH,Lien TJ,Chen PJ,Huang TP,Tarng DC

更新日期：2014-01-01 00:00:00

abstract：:Proteinuria is characteristic of many glomerular conditions, and often exceeds 2-3 g/24 h. There are several possible routes by which such profuse proteinuria might contribute to progression of the underlying pathology, whatever its type. First, proteinuria leads to a transit of protein through glomerular structures, ...

journal_title：American journal of nephrology

authors： Cameron JS

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND/AIMS:Patients with chronic renal failure (CRF) secondary to diabetes mellitus show a high incidence of atherosclerosis with its thrombotic complications. Both CRF and type 2 diabetes mellitus (DM2) results in fibrinolysis defects causally related to atherogenesis and thrombogenesis. It is not well known whet...

journal_title：American journal of nephrology

authors： Opatrný K Jr,Zemanová P,Mares J,Vít L,Opatrná S,Sefrna F,Hejda V,Tomsů M,Eiselt J,Massry SG

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Transglutaminase 2 (TGM2) is a calcium-dependent enzyme that can cross-link nearly all extracellular matrix (ECM) proteins and can facilitate cell-ECM interaction through integrins. Given the importance of the ECM in vascular calcification we tested the hypothesis that increased TGM2 activity may accelerate ...

journal_title：American journal of nephrology

authors： Chen NX,O'Neill K,Chen X,Kiattisunthorn K,Gattone VH,Moe SM

更新日期：2013-01-01 00:00:00

abstract：:A renal transplant recipient with a remote history of end-stage renal disease due to postpartum hemolytic-uremic syndrome (HUS) presented with acute renal failure after having stable renal allograft function for 9 years. A diagnosis of thrombotic microangiopathy was made based on clinical and histologic findings at re...

journal_title：American journal of nephrology

authors： Gohh RY,Williams ME,Crosson AW,Federman M,Zambetti FX

更新日期：1997-01-01 00:00:00

abstract：:Hyperlipidemia is common in patients with glomerular proteinuria. It may contribute to atherosclerotic complications and accelerate glomerular damage. Early trials of the fibric acid derivative clofibrate led to a myositis syndrome causing many nephrologists to abandon attempts at treatment of nephrotic hyperlipidemia...

journal_title：American journal of nephrology

authors： Appel GB,Appel AS

更新日期：1990-01-01 00:00:00

abstract：AIMS:We aimed to assess humoral immune response to the influenza vaccine in adult kidney transplant recipients (KTRs) subjected to two immunosuppressive regimens containing either mycophenolate mofetil (MMF) or azathioprine (Aza). METHODS:40 eligible KTRs (24 treated with Aza [KTRs-Aza] and 16 treated with MMF [KTRs-M...

journal_title：American journal of nephrology

authors： Keshtkar-Jahromi M,Argani H,Rahnavardi M,Mirchi E,Atabak S,Tara SA,Gachkar L,Noori-Froothghe A,Mokhtari-Azad T

更新日期：2008-01-01 00:00:00