Late renal allograft failure secondary to thrombotic microangiopathy associated with disseminated malignancy.

Abstract:

:A renal transplant recipient with a remote history of end-stage renal disease due to postpartum hemolytic-uremic syndrome (HUS) presented with acute renal failure after having stable renal allograft function for 9 years. A diagnosis of thrombotic microangiopathy was made based on clinical and histologic findings at renal biopsy. She was treated conservatively, never regaining graft function and ultimately succumbing from her overwhelming tumor load approximately 6 months following diagnosis of her malignancy. To our knowledge, this is the first report of thrombotic microangiopathy associated with disseminated malignancy resulting in renal allograft failure.

journal_name

Am J Nephrol

authors

Gohh RY,Williams ME,Crosson AW,Federman M,Zambetti FX

doi

10.1159/000169094

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

176-80

issue

2

eissn

0250-8095

issn

1421-9670

journal_volume

17

pub_type

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