Abstract:
:A young woman presented with nephrotic syndrome due to membranous nephropathy and a localized form of giant lymph node hyperplasia (Castleman's disease) occurring as a large intra-abdominal mass. Five months after surgical removal of the mass, only mild proteinuria persisted. Twenty months later a second kidney biopsy showed a near-normal morphology. Six years later the patient was free of symptoms and had normal urinalysis. Reviewing the pertinent literature, it seems to be the first case of a biopsy-proven cure of membranous nephropathy in a patient with membranous nephropathy and Castleman's disease.
journal_name
Am J Nephroljournal_title
American journal of nephrologyauthors
Ruggieri G,Barsotti P,Coppola G,Spinelli C,Balducci A,Ventola FR,d'Adamo G,Tata MV,Marinozzi Vdoi
10.1159/000168127subject
Has Abstractpub_date
1990-01-01 00:00:00pages
323-8issue
4eissn
0250-8095issn
1421-9670journal_volume
10pub_type
杂志文章,评审abstract::John Bostock has a reasonable claim to being one of the first chemical pathologists. Most of his work was done before that of William Prout, with whom both he and Bright were in contact. Bostock's work was done about the same time as that of his friends and colleagues Marcet and Wollaston. Although other, notably Crui...
journal_title:American journal of nephrology
pub_type: 传,历史文章,杂志文章
doi:10.1159/000168749
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:This study aimed at evaluating the after effects of a single bout of aerobic exercise on muscle sympathetic nerve activity (MSNA), peripheral vascular resistance and blood pressure (BP) in stages 2-3 chronic kidney disease (CKD) patients. We hypothesized that CKD patients present a greater decline in these v...
journal_title:American journal of nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1159/000445443
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Patients with primary hyperoxaluria (PH) overproduce oxalate which is eliminated via the kidneys. If end-stage kidney disease develops they are at high risk for systemic oxalosis, unless adequate oxalate is removed during hemodialysis (HD) to equal or exceed ongoing oxalate production. The purpose of this st...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000360624
更新日期:2014-01-01 00:00:00
abstract::We describe a 78-year-old patient with nephrotic syndrome due to minimal-change glomerulopathy, associated with a renal adenocarcinoma. Oliguric acute renal failure requiring hemodialysis was also observed. Surgical removal of the tumor and corticosteroid therapy resulted in resolution of the nephrotic state and impro...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000013365
更新日期:1998-01-01 00:00:00
abstract::Proteinuria is characteristic of many glomerular conditions, and often exceeds 2-3 g/24 h. There are several possible routes by which such profuse proteinuria might contribute to progression of the underlying pathology, whatever its type. First, proteinuria leads to a transit of protein through glomerular structures, ...
journal_title:American journal of nephrology
pub_type: 杂志文章,评审
doi:10.1159/000168199
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Increased mortality and morbidity are reported in association with high ultrafiltration rate (UFR) and with long dialysis recovery time (DRT). We studied the association between UFR and DRT. METHODS:This is a cross-sectional, observational study was conducted. Patients on thrice-weekly hemodialysis (HD) wit...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000476076
更新日期:2017-01-01 00:00:00
abstract:AIMS:We aimed to assess humoral immune response to the influenza vaccine in adult kidney transplant recipients (KTRs) subjected to two immunosuppressive regimens containing either mycophenolate mofetil (MMF) or azathioprine (Aza). METHODS:40 eligible KTRs (24 treated with Aza [KTRs-Aza] and 16 treated with MMF [KTRs-M...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000119742
更新日期:2008-01-01 00:00:00
abstract::There is still debate as to the preferred extracorporeal treatment modality for severe lithium intoxication. Because lithium is readily diffusable, intermittent hemodialysis is usually performed. However, this bares the risk of a post-dialysis rebound concentration and, in the case of severe lithium poisoning collapse...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000013627
更新日期:2000-09-01 00:00:00
abstract::Hemolytic-uremic syndrome following quinine ingestion is a newly described phenomenon, with just two previous descriptions of 4 cases in the literature. We describe a 5th case. The reaction may be mediated by the presence of antibodies reactive against platelets in the presence of quinine. Treatment has included use o...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000168444
更新日期:1992-01-01 00:00:00
abstract::Tuberculosis associated with dialysis was studied at the Artificial Kidney Unit (AKU) in Abha, Saudi Arabia. There were 13 tuberculosis patients out of 270 patients on maintenance hemodialysis from August 1986 to July 1993, a prevalence of 4.8%. Ten (77%) were female and 3 (23%) were male, mean age of 51.23 +/- 11.62 ...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000169068
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND/AIMS:Advanced glycation end products (AGEs) induce epithelial mesenchymal transition (EMT) in renal proximal tubular epithelial cells (PTECs) by promoting the two EMT regulators, transforming growth factor beta (TGF-β) and connective tissue growth factor (CTGF). However, the exact signaling mechanism remains...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000381464
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:It has been demonstrated that phosphate uptake through the type III sodium-dependent phosphate co-transporter, Pit-1, induced apoptosis of aortic vascular smooth muscle cells and endothelial cells in vitro. However, the apoptotic effects of high phosphate (HP) level in human peritoneal mesothelial cells (HPM...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000329081
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND/AIMS:Vitamin D insufficiency drives secondary hyperparathyroidism (SHPT) and is associated with increased cardiovascular mortality in patients with chronic kidney disease (CKD). SHPT is poorly addressed by current vitamin D repletion options. The present study evaluated a novel investigational vitamin D repl...
journal_title:American journal of nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1159/000369939
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Nephrology research is expanding, and harnessing the much-needed information and data for the practice of evidence-based medicine is becoming more challenging. In this study, we used the natural language processing and text mining approach to mitigate some of these challenges. METHODS:We analyzed 17,412 abs...
journal_title:American journal of nephrology
pub_type: 杂志文章,评审
doi:10.1159/000504871
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:To evaluate the predictive value of dialysate interleukin-6 (IL-6) representing local subclinical intraperitoneal inflammation for the development of peritonitis in continuous ambulatory peritoneal dialysis (CAPD) patients. METHODS:Stable prevalent CAPD patients were enrolled in this prospective study. IL-6...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000489271
更新日期:2018-01-01 00:00:00
abstract::Shortage of kidney donor is still a major limitation for renal transplantation programs. This review focuses on the emerging practices, adopted to increase transplant activities, of expanding the criteria for donor and recipient selection without exposing the recipient to the drawbacks of a graft with inadequate nephr...
journal_title:American journal of nephrology
pub_type: 杂志文章,评审
doi:10.1159/000072055
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:The impact of socioeconomic factors on arteriovenous fistula (AVF) creation in hemodialysis (HD) patients is not well understood. We assessed the association of area and individual-level indicators of poverty and health care insurance on AVF use among incident end-stage renal disease (ESRD) patients initiate...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000441804
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:In autosomal dominant polycystic kidney disease, renoprotective treatment with a vasopressin V2 receptor antagonist (V2RA) is given in a fixed dose (FD). Disease progression and drug habituation could diminish treatment efficacy. We investigated whether the renoprotective effect of the V2RA can be improved b...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000448693
更新日期:2016-01-01 00:00:00
abstract::The platelet content of adenosine triphosphate (ATP), adenosine diphosphate (ADP), serotonin and ouabain-insensitive, magnesium-dependent adenosine triphosphatase (ATPase) was determined in patients with chronic renal failure, patients on chronic hemodialysis, and kidney transplant recipients. Platelet ATP content was...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000166482
更新日期:1981-01-01 00:00:00
abstract:BACKGROUND/AIMS:The elderly are the fastest growing subpopulation with end-stage renal disease. The goal of our study was to define characteristics of elderly patients who were considered ineligible for transplantation compared to those who were listed. METHODS:984 patients were referred for evaluation during a 2-year...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000354483
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Tacrolimus has been reported to be effective in refractory nephrotic syndrome, such as focal segmental glomerulosclerosis and membranous nephropathy. Some IgA nephropathy (IgAN) patients with massive proteinuria showed resistance to steroids and/or cytotoxic immunosuppressants based on the supportive therapy...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000337175
更新日期:2012-01-01 00:00:00
abstract::Erythropoietin-stimulating agent (ESA) hyporesponsiveness is aggravated by chronic inflammation in maintenance hemodialysis (MHD) patients. Dyslipidemia is prevalent in MHD patients. Statin therapy has been demonstrated to not only be effective in lowering lipid levels, but also numerous pleiotropic effects including ...
journal_title:American journal of nephrology
pub_type: 临床试验,杂志文章
doi:10.1159/000169658
更新日期:2009-01-01 00:00:00
abstract::Renal disease is a common complication in malaria infection. In acute falciparum malaria renal involvement is usually mild, but in severe disease acute renal failure is a major problem. Acute renal failure has been attributed to ischaemic tubular necrosis from hypovolaemia resulting from vasodilatation due to endothel...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000013611
更新日期:2000-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVE:In the Systolic Blood Pressure Intervention Trial, the possible relationships between acute kidney injury (AKI) and risk of major cardiovascular events and death are not known. STUDY DESIGN:Post hoc analysis of a multicenter, randomized, controlled, open-label clinical trial. SETTING AND PARTI...
journal_title:American journal of nephrology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1159/000499574
更新日期:2019-01-01 00:00:00
abstract::To elucidate the relationship between the renal regulation of sodium and calcium excretion at extremes of sodium intake, we studied 6 normal men ingesting a fixed, 400 mg/day calcium intake and four levels of sodium intake from 10 to 1,500 mEq/day. Serum ionized calcium was not influenced by sodium intake. Blood press...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000166496
更新日期:1981-01-01 00:00:00
abstract::We have compared the renal effects of ioxitalamate, ioxaglate, and iopamidol in patients with chronic renal failure. Sixty consecutive patients with an estimated creatinine clearance (ECRCl) less than 60 ml/min were randomly assigned to receive either ioxitalamate, iopamidol, or ioxaglate. All patients received 500 cm...
journal_title:American journal of nephrology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000168328
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:More than 50% of American adolescents and adults report having used illicit drugs in their lifetime. We examined the association of lifetime opiate and cocaine use with reduced kidney function, albuminuria and rapid kidney function decline among urban-dwelling adults. METHODS:Our prospective cohort included...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000452348
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND/AIMS:We previously reported that patients with chronic kidney disease (CKD) receiving warfarin therapy and whose international normalized ratio increases to >3.0 may develop acute kidney injury (AKI) as a result of glomerular hemorrhage and formation of obstructive red blood cell (RBC) casts. We named this c...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000337918
更新日期:2012-01-01 00:00:00
abstract::Recent studies have focused attention on the possible role of zinc depletion in the pathogenesis of uremic symptoms such as dysgeusia and impotence. The present studies were undertaken to evaluate the prevalence of zinc deficiency and abnormalities of zinc metabolism in patients with end-stage renal disease. A total o...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000167247
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:Living donor liver transplantation (LDLT) patients run the risk of developing acute kidney injury (AKI) and subsequent chronic kidney disease, affecting morbidity and mortality. Sevoflurane has anti-inflammation properties, and renal ischemia/reperfusion under sevoflurane anesthesia resulted in drastic impro...
journal_title:American journal of nephrology
pub_type: 杂志文章
doi:10.1159/000319623
更新日期:2010-01-01 00:00:00