Membranous nephropathy associated with giant lymph node hyperplasia. A case report with histological and ultrastructural studies.

Abstract:

:A young woman presented with nephrotic syndrome due to membranous nephropathy and a localized form of giant lymph node hyperplasia (Castleman's disease) occurring as a large intra-abdominal mass. Five months after surgical removal of the mass, only mild proteinuria persisted. Twenty months later a second kidney biopsy showed a near-normal morphology. Six years later the patient was free of symptoms and had normal urinalysis. Reviewing the pertinent literature, it seems to be the first case of a biopsy-proven cure of membranous nephropathy in a patient with membranous nephropathy and Castleman's disease.

journal_name

Am J Nephrol

authors

Ruggieri G,Barsotti P,Coppola G,Spinelli C,Balducci A,Ventola FR,d'Adamo G,Tata MV,Marinozzi V

doi

10.1159/000168127

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

323-8

issue

4

eissn

0250-8095

issn

1421-9670

journal_volume

10

pub_type

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