Role of aldose reductase in the peritoneal changes of patients undergoing peritoneal dialysis.

abstract：:Accelerated atherosclerosis is both a cause and a consequence of chronic renal failure. Vascular smooth muscle cells (VSMCs) are an important component of atherosclerotic plaques, responsible for promoting plaque stability in advanced lesions. In contrast, VSMC apoptosis has been implicated in a number of deleterious ...

journal_title：American journal of nephrology

authors： Clarke M,Bennett M

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Henoch-Schönlein Purpura (HSP) is a common childhood vasculitis with manifestations in numerous organ systems, including glomerulonephritis. Patients with more severe HSP-associated glomerulonephritis may develop chronic renal failure. Currently, no widely accepted treatment protocols exist for patients with...

journal_title：American journal of nephrology

authors： Flynn JT,Smoyer WE,Bunchman TE,Kershaw DB,Sedman AB

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:We investigated the gender differences in the effect of ACE I/D and AGT M235T polymorphisms on the prognosis of diabetic nephropathy (DN). METHODS:A total of 525 type 2 diabetics were enrolled to participate in this prospective observational study. ACE and AGT gene polymorphisms were analyzed by polymerase ...

journal_title：American journal of nephrology

authors： Tien KJ,Hsiao JY,Hsu SC,Liang HT,Lin SR,Chen HC,Hsieh MC

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:Three different apo E alleles (E2, E3 and E4) produce apo E isoproteins, which regulate the metabolism of lipoproteins. This study investigated the apo E polymorphisms as a prognostic factor for the development of diabetic nephropathy (DN). METHODS:A total of 525 type 2 diabetic patients were enrolled ...

journal_title：American journal of nephrology

authors： Tien KJ,Tu ST,Chou CW,Yang CY,Hsiao JY,Shin SJ,Chen HC,Hsieh MC

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The value of chronic kidney disease (CKD) screening in the general population remains unclear but may be beneficial in populations with high disease prevalence. We examined risk factors for albuminuria among participants in a state-wide CKD screening program in Hawaii. METHODS:The National Kidney Foundation...

journal_title：American journal of nephrology

authors： Wong LL,Kalantar-Zadeh K,Page V,Hayashida G,You AS,Rhee CM

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND/AIMS:Familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC) is a rare renal tubular disorder complicated by progressive renal failure during childhood or adolescence. Recently, causative mutations in the CLDN19 gene have been identified in FHHNC patients presenting with severe ocular involv...

journal_title：American journal of nephrology

authors： Naeem M,Hussain S,Akhtar N

更新日期：2011-01-01 00:00:00

abstract：:The medical history of salt begins in ancient times and is closely related to different aspects of human history. Salt may be extracted from sea water, mineral deposits, surface encrustations, saline lakes and brine springs. In many inland areas, wood was used as a fuel source for evaporation of brine and this practic...

journal_title：American journal of nephrology

authors： Cirillo M,Capasso G,Di Leo VA,De Santo NG

更新日期：1994-01-01 00:00:00

abstract：:Autopsy reports on 155 successive end-stage renal disease (ESRD) patients and 147 control patients without ESRD, matched for age, race and gender, were collected. Cystic transformation of the kidneys was noted in 58% of the ESRD patients and 13.6% of the control patients. There were 25 ESRD patients with renal adenoma...

journal_title：American journal of nephrology

authors： Miller LR,Soffer O,Nassar VH,Kutner MH

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Interest in nephrology careers is declining, possibly due to perceptions of the field and/or training aspects. Understanding practices of medical schools successfully instilling nephrology interest could inform efforts to attract leading candidates to the specialty. METHODS:The American Society of Nephrolog...

journal_title：American journal of nephrology

authors： Sozio SM,Pivert KA,Shah HH,Chakkera HA,Asmar AR,Varma MR,Morrow BD,Patel AB,Leight K,Parker MG

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:The association between chronic kidney disease (CKD) awareness and healthy behaviors is unknown. We examined whether CKD self-recognition is associated with healthy behaviors and achieving risk-reduction targets known to decrease risk of cardiovascular morbidity and CKD progression. METHODS:CKD awarene...

journal_title：American journal of nephrology

authors： Tuot DS,Plantinga LC,Judd SE,Muntner P,Hsu CY,Warnock DG,Gutiérrez OM,Safford M,Powe NR,McClellan WM,REGARDS Investigators.

更新日期：2013-01-01 00:00:00

abstract：:During the period from April 4, 1988, to April 20, 1988, nine pyrogenic reactions and five gram-negative bacteremias occurred in 11 patients undergoing dialysis. All pyrogenic reactions and gram-negative bacteremias occurred among patients in whom a reprocessed dialyzer was used. The rate of pyrogenic reactions or bac...

journal_title：American journal of nephrology

authors： Beck-Sague CM,Jarvis WR,Bland LA,Arduino MJ,Aguero SM,Verosic G

更新日期：1990-01-01 00:00:00

abstract：:Atherosclerotic diseases (ASD) are the major cause of mortality and morbidity in patients on hemodialysis (HD). To evaluate the significance and usefulness of atherogenic indices, we examined lipoprotein(a) (Lp(a)), remnant-like particles cholesterol (RLP.C), homocysteine (Hcy), cardiac troponin T (TnT), and ankle-arm...

journal_title：American journal of nephrology

authors： Oishi K,Nagake Y,Yamasaki H,Fukuda S,Ichikawa H,Ota K,Makino H

更新日期：2000-03-01 00:00:00

abstract：:Both the Old Testament and the Talmud contain a great deal of information on medicine, nephrology, health and disease. The basic premise of early Jewish medicine is based on the notion that disease is due to structural changes in internal organs. This is in contrast to the mythical dogma of humoralism as the basis of ...

journal_title：American journal of nephrology

authors： Massry SG,Smogorzewski M,Hazani E,Shasha SM

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Malnutrition-inflammation score (MIS) is a comprehensive and quantitative system to assess malnutrition-inflammation complex syndrome, and a strong correlation between MIS and morbidity/mortality in maintenance hemodialysis (MHD) patients had been demonstrated. However, there is no cut-off value of MIS to ca...

journal_title：American journal of nephrology

authors： Ho LC,Wang HH,Peng YS,Chiang CK,Huang JW,Hung KY,Hu FC,Wu KD

更新日期：2008-01-01 00:00:00

abstract：UNLABELLED:Although it is anticipated that most patients with renal insufficiency will progress towards end-stage renal disease (ESRD) there have been few population-based studies to validate this assumption. We examined serial creatinines from 3,874 anonymous patients at an urban VA medical center who had a baseline c...

journal_title：American journal of nephrology

authors： Fink JC,Salmanullah M,Blahut SA,Weir MR,Sawyer R,Henrich WL,Hise MK

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Henoch-Schönlein purpura (HSP) is a form of systemic vasculitis that can progress to Henoch-Schönlein purpura nephritis (HSPN), and the most effective treatment remains controversial. Our aim was to compare the effects of oral mycophenolate mofetil (MMF) with low-dose prednisone and the full-dose corticoster...

journal_title：American journal of nephrology

authors： Ren P,Han F,Chen L,Xu Y,Wang Y,Chen J

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Inflammation and increased erythropoiesis stimulating agents (ESA) requirement are frequently associated in patients on dialysis. On-line hemodiafiltration (ol-HDF), putting together high levels of diffusion, and convection could improve both conditions. However, it is still not known which depurative compon...

journal_title：American journal of nephrology

authors： Movilli E,Camerini C,Gaggia P,Zubani R,Feller P,Salviani C,Facchini A,Cancarini G

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:End-stage renal disease (ESRD) is a disease with an aging population and a high prevalence of cognitive impairment affecting quality of life, health care costs and mortality. Structural changes in the brain with decreased white matter integrity have been observed in ESRD. Understanding the changes in cogniti...

journal_title：American journal of nephrology

authors： Gupta A,Lepping RJ,Yu AS,Perea RD,Honea RA,Johnson DK,Brooks WM,Burns JM

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Telomere attrition is a novel risk factor for cardiovascular disease. Studies of telomere length in relation to kidney function are limited. We explored the association of kidney function with telomere length and telomere shortening. METHODS:The Heart and Soul Study is a longitudinal study of patients with ...

journal_title：American journal of nephrology

authors： Bansal N,Whooley MA,Regan M,McCulloch CE,Ix JH,Epel E,Blackburn E,Lin J,Hsu CY

更新日期：2012-01-01 00:00:00

abstract：:To elucidate the prevalence and clinical implications of antineutrophil cytoplasmic antibody (ANCA) in lupus nephritis (LN), we examined ANCA by indirect immunofluorescence and by ELISA against antilactoferrin (anti-LF) and antimyeloperoxidase (anti-MPO) antibody. To discriminate perinuclear ANCA (pANCA) with antinucl...

journal_title：American journal of nephrology

authors： Chin HJ,Ahn C,Lim CS,Chung HK,Lee JG,Song YW,Lee HS,Han JS,Kim S,Lee JS

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:The objective of this study was to investigate the role of bone morphogenetic protein (BMP) signal transduction in the pathogenesis of calciphylaxis. METHODS:Skin biopsy specimens were obtained from 18 patients with, and 12 patients without, calciphylaxis. Tissue sections were stained with antibodies direct...

journal_title：American journal of nephrology

authors： Nigwekar SU,Jiramongkolchai P,Wunderer F,Bloch E,Ichinose R,Nazarian RM,Thadhani RI,Malhotra R,Bloch DB

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The identification of nephrin and CD2AP, podocyte proteins which modulate the properties of glomerular barrier selectivity, has made it possible to unravel the mechanisms undergoing foot process effacement and proteinuria. Here we explored the role of nephrin and CD2AP together with the integrity of the slit...

journal_title：American journal of nephrology

authors： Gagliardini E,Benigni A,Tomasoni S,Abbate M,Kalluri R,Remuzzi G

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Published reports examining the efficacy and safety of glucocorticoids for preserving renal function in immunoglobulin A nephropathy (IgAN) have yielded conflicting results. To systematically evaluate the efficacy and safety of glucocorticoids agents for IgAN, we conducted a meta-analysis of the published ra...

journal_title：American journal of nephrology

authors： Cheng J,Zhang X,Zhang W,He Q,Tao X,Chen J

更新日期：2009-01-01 00:00:00

abstract：:Dialysis patients have increased susceptibility to infection and this is, in part, due to impaired phagocytic and bactericidal activities of polymorphonuclear leukocytes (PMNL). The mechanisms responsible for the reduced phagocytosis are not known. Dialysis patients have elevated blood levels of parathyroid hormone (P...

journal_title：American journal of nephrology

authors： Alexiewicz JM,Smogorzewski M,Fadda GZ,Massry SG

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) occurs frequently in the intensive care unit. A primary cause is renal ischemia/reperfusion (I/R) injury, during which excess reactive oxygen species (ROS) are produced. ROS subsequently damage renal cells, leading to the development of AKI. Here, we investigated whether renal I/R i...

journal_title：American journal of nephrology

authors： Yamamoto S,Hagiwara S,Hidaka S,Shingu C,Goto K,Kashima K,Noguchi T

更新日期：2011-01-01 00:00:00

abstract：:Berengario da Carpi was magister of anatomy and surgery at the University of Bologna from 1502 to 1527. Eustachio and Falloppia defined him as 'the restaurator of anatomy'. He was a great surgeon, anatomist and physician of illustrious patients including Lorenzo II dei Medici, Giovanni dalle Bande Nere, Galeazzo Palla...

journal_title：American journal of nephrology

authors： De Santo NG,Bisaccia C,De Santo LS,De Santo RM,Di Leo VA,Papalia T,Cirillo M,Touwaide A

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Placental growth factor (PlGF), a member of the vascular endothelial growth factor (VEGF) family, has recently emerged as a predictor of survival and cardiovascular risk. Along with others, we have shown an independent association between PlGF and cardiovascular events in CKD patients, but not much is known ...

journal_title：American journal of nephrology

authors： Matsui M,Samejima K,Takeda Y,Tanabe K,Morimoto K,Okamoto K,Tagawa M,Onoue K,Okayama S,Kawata H,Kawakami R,Akai Y,Saito Y

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Hyperkalemia is common in patients receiving maintenance hemodialysis. However, few studies have examined the association between serum potassium level and mortality. METHODS:This study used annual cohorts of hemodialysis patients during 2007-2010. To determine hyperkalemia prevalence, monthly hyperkalemia ...

journal_title：American journal of nephrology

authors： Yusuf AA,Hu Y,Singh B,Menoyo JA,Wetmore JB

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Hypertension often accompanies chronic kidney disease (CKD), and diuretics are widely prescribed to reduce blood pressure (BP). Chlorthalidone (CTD) is a thiazide-like diuretic and an effective antihypertensive drug, yet little data exist to support its use in treating hypertension in individuals with advanc...

journal_title：American journal of nephrology

authors： Agarwal R,Cramer AE,Balmes-Fenwick M,Sinha AD,Ouyang F,Tu W

更新日期：2020-01-01 00:00:00

abstract：:Thirty-one renal transplant recipients, submitted to treatment with cyclosporin in association with other immunosuppressive agents, were also treated for 9 months with two hydroxymethylglutaryl coenzyme A reductase inhibitors, simvastatin (10 mg/day) or pravastatin (20 mg/day), for concomitant hypercholesterolemia and...

journal_title：American journal of nephrology

authors： Capone D,Stanziale P,Gentile A,Imperatore P,Pellegrino T,Basile V

更新日期：1999-01-01 00:00:00