Mutation in the tight-junction gene claudin 19 (CLDN19) and familial hypomagnesemia, hypercalciuria, nephrocalcinosis (FHHNC) and severe ocular disease.

abstract：:A young woman presented with nephrotic syndrome due to membranous nephropathy and a localized form of giant lymph node hyperplasia (Castleman's disease) occurring as a large intra-abdominal mass. Five months after surgical removal of the mass, only mild proteinuria persisted. Twenty months later a second kidney biopsy...

journal_title：American journal of nephrology

authors： Ruggieri G,Barsotti P,Coppola G,Spinelli C,Balducci A,Ventola FR,d'Adamo G,Tata MV,Marinozzi V

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:There is a higher risk of gastrointestinal (GI) bleeding in patients treated with dabigatran versus warfarin. We analyzed the impact of renal function on the relative risk of bleeding in patients converted to dabigatran. METHODS:Patients aged ≥65 years who received anticoagulation with warfarin for a minimu...

journal_title：American journal of nephrology

authors： Kalil RS,Kaboli PJ,Liu X,Vaughan-Sarrazin M

更新日期：2016-01-01 00:00:00

abstract：:A national sample of dialysis physicians was used to obtain data for a comparison of patient characteristics, comorbid conditions and treatment patterns associated with the five leading causes of end-stage renal disease (ESRD). The data are used to assess trends in physician care for ESRD patients and likely changes i...

journal_title：American journal of nephrology

authors： Radecki SE,Nissenson AR

更新日期：1989-01-01 00:00:00

abstract：:Fifty-four patients with noninsulin-dependent diabetes mellitus, who had established nephropathy, were examined to evaluate the risk factors for the progression of diabetic nephropathy. Time-averaged values of blood pressure, serum total cholesterol and fasting plasma glucose concentrations, and the degree of proteinu...

journal_title：American journal of nephrology

authors： Yokota C,Kimura G,Inenaga T,Kawano Y,Matsuoka H,Omae T

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Oxidative stress (OS) and asymmetric dimethylarginine (ADMA) are accepted as nonclassical cardiovascular risk factors in end-stage renal disease patients. To clarify the role of these factors in the atherosclerotic process, we investigated if OS and ADMA are associated with common carotid artery intima media...

journal_title：American journal of nephrology

authors： Kocak H,Gumuslu S,Ermis C,Mahsereci E,Sahin E,Gocmen AY,Ersoy F,Suleymanlar G,Yakupoglu G,Tuncer M

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Pulmonary arterial hypertension (PAH) may lead to right heart failure and subsequently alter glomerular filtration rates (GFR). Chronic kidney disease (CKD, GFR <60 mL/min/1.73 m2) may also adversely affect PAH prognosis. This study aimed to assess how right heart hemodynamics was associated with reduced est...

journal_title：American journal of nephrology

authors： Bitker L,Sens F,Payet C,Turquier S,Duclos A,Cottin V,Juillard L

更新日期：2018-01-01 00:00:00

abstract：:Thirty-one renal transplant recipients, submitted to treatment with cyclosporin in association with other immunosuppressive agents, were also treated for 9 months with two hydroxymethylglutaryl coenzyme A reductase inhibitors, simvastatin (10 mg/day) or pravastatin (20 mg/day), for concomitant hypercholesterolemia and...

journal_title：American journal of nephrology

authors： Capone D,Stanziale P,Gentile A,Imperatore P,Pellegrino T,Basile V

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND/AIMS:Apoptosis contributes to cyclosporine (CsA)-induced renal cell death. This study tested the effects of CsA-induced endoplasmic reticulum (ER) stress on apoptotic cell death in an experimental model of chronic CsA nephropathy. METHODS:CsA (15 mg/kg per day) was given to rats for 7 or 28 days. The ER str...

journal_title：American journal of nephrology

authors： Han SW,Li C,Ahn KO,Lim SW,Song HG,Jang YS,Cho YM,Jang YM,Ghee JY,Kim JY,Kim SH,Kim J,Kwon OJ,Yang CW

更新日期：2008-01-01 00:00:00

abstract：:Renal function and life expectancy can be improved by aggressive antihypertensive therapy in severe hypertension. However, most reports of severe hypertension and renal failure concern primary hypertensive states. 3 cases of primary renal disease, 1 glomerular, 1 obstructive and 1 of chronic pyelonephritis, are descri...

journal_title：American journal of nephrology

authors： Friedlaender MM,Rubinger D,Popovtzer MM

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:The objective of this study was to investigate the role of bone morphogenetic protein (BMP) signal transduction in the pathogenesis of calciphylaxis. METHODS:Skin biopsy specimens were obtained from 18 patients with, and 12 patients without, calciphylaxis. Tissue sections were stained with antibodies direct...

journal_title：American journal of nephrology

authors： Nigwekar SU,Jiramongkolchai P,Wunderer F,Bloch E,Ichinose R,Nazarian RM,Thadhani RI,Malhotra R,Bloch DB

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Renal insufficiency is a well-described risk factor for perioperative morbidity and shortened survival after major vascular procedures. Due to the potential inaccuracy of serum creatinine levels alone in measuring kidney function, our aim was to determine whether estimated creatinine clearance more consisten...

journal_title：American journal of nephrology

authors： Maithel SK,Pomposelli FB,Williams M,Sheahan MG,Scovell SD,Campbell DR,LoGerfo FW,Hamdan AD

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:African Americans (AAs) suffer the widest gaps in chronic kidney disease (CKD) outcomes compared to Caucasian Americans (CAs) and this is because of the disparities that exist in both health and healthcare. In fact, the prevalence of CKD is 3.5 times higher in AAs compared to CAs. The disparities exist at al...

journal_title：American journal of nephrology

authors： Harding K,Mersha TB,Vassalotti JA,Webb FA,Nicholas SB

更新日期：2017-01-01 00:00:00

abstract：:Collapsing glomerulopathy is a pattern of renal injury that is seen in association with human immunodeficiency virus (HIV) infection. Patients with this HIV-associated nephropathy (HIVAN) present nephrotic syndrome and rapid deterioration of the renal function. There is no proven effective therapy for HIVAN, and the m...

journal_title：American journal of nephrology

authors： Morales E,Martinez A,Sánchez-Ayuso J,Gutierrez E,Mateo S,Martínez MA,Herrero JC,Praga M

更新日期：2002-07-01 00:00:00

abstract：:To evaluate the determinants of rhabdomyolysis in the diabetic state, we compared biochemical and clinical features of diabetic patients with (group 1, 41 patients) and without (group 2, 36 patients) rhabdomyolysis. There was no difference in values for serum potassium, bicarbonate, phosphate and calcium between the t...

journal_title：American journal of nephrology

authors： Singhal PC,Abramovici M,Ayer S,Desroches L

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Obesity is an independent risk factor for morbidity and mortality in cardiovascular diseases not only in the general population, but also in hemodialysis (HD) patients. We previously reported that an increased visceral fat area (VFA) determined using computed tomography (CT) scans was associated with atheros...

journal_title：American journal of nephrology

authors： Okamoto T,Morimoto S,Ikenoue T,Furumatsu Y,Ichihara A

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:More than 50% of American adolescents and adults report having used illicit drugs in their lifetime. We examined the association of lifetime opiate and cocaine use with reduced kidney function, albuminuria and rapid kidney function decline among urban-dwelling adults. METHODS:Our prospective cohort included...

journal_title：American journal of nephrology

authors： Novick T,Liu Y,Alvanzo A,Zonderman AB,Evans MK,Crews DC

更新日期：2016-01-01 00:00:00

abstract：:In order to evaluate the changes in causes and outcome of acute renal failure (ARF) during the years 1975-1989, 710 patients treated in our dialysis center were analyzed. We compared the etiology, the severity and catabolic state of ARF, the techniques of renal replacement therapy, which were employed and the ages and...

journal_title：American journal of nephrology

authors： Biesenbach G,Zazgornik J,Kaiser W,Grafinger P,Stuby U,Necek S

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:The value of chronic kidney disease (CKD) screening in the general population remains unclear but may be beneficial in populations with high disease prevalence. We examined risk factors for albuminuria among participants in a state-wide CKD screening program in Hawaii. METHODS:The National Kidney Foundation...

journal_title：American journal of nephrology

authors： Wong LL,Kalantar-Zadeh K,Page V,Hayashida G,You AS,Rhee CM

更新日期：2017-01-01 00:00:00

abstract：:One hundred twenty-eight hemodialysis patients and 64 medical personnel consisting of dialysis nurses and technicians, hemodialysis access surgeons and nephrologists were surveyed about their preferences and concerns in regard to the hemodialysis vascular access. The access preferred by physicians was the A-V fistula ...

journal_title：American journal of nephrology

authors： Bay WH,Van Cleef S,Owens M

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:We hypothesized that the difference between the prescribed end-dialysis body weight, defined end-dialysis over-weight (edOW; kg), and the body weight which is actually attained could impact survival in hemodialysis (HD) patients. The aim of this prospective observational study was to evaluate if edOW could i...

journal_title：American journal of nephrology

authors： Movilli E,Camerini C,Gaggia P,Zubani R,Feller P,Poiatti P,Pola A,Carli O,Cancarini G

更新日期：2013-01-01 00:00:00

abstract：:Ultramorphological images and details of an uremic echinocyte are shown. The images confirm the existence of uremic echinocytes and demonstrate that atomic force microscopy can provide high-resolution images of cell surfaces. ...

journal_title：American journal of nephrology

authors： Zachée P,Boogaerts M,Snauwaert J,Hellemans L

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:It is uncertain whether kidneys from marginal donors are suitable for live kidney transplantation. In deceased donor kidneys, tubular cell senescence affects allograft function. However, the degree of cell senescence in a living donor kidney with marginal factors has not been reported. In this study, we asse...

journal_title：American journal of nephrology

authors： Sofue T,Kushida Y,Ozaki T,Moritoki M,Nishijima Y,Ohsaki H,Ueda N,Kakehi Y,Nishiyama A,Minamino T

更新日期：2018-01-01 00:00:00

abstract：:Berengario da Carpi was magister of anatomy and surgery at the University of Bologna from 1502 to 1527. Eustachio and Falloppia defined him as 'the restaurator of anatomy'. He was a great surgeon, anatomist and physician of illustrious patients including Lorenzo II dei Medici, Giovanni dalle Bande Nere, Galeazzo Palla...

journal_title：American journal of nephrology

authors： De Santo NG,Bisaccia C,De Santo LS,De Santo RM,Di Leo VA,Papalia T,Cirillo M,Touwaide A

更新日期：1999-01-01 00:00:00

abstract：:Although the acute nephrotoxicity of cisplatin has been well documented, long-term follow-up studies are scanty. We have evaluated the renal function in 35 patients who have had completed therapy with cisplatin at least 3 months before the study. All patients had normal serum creatinine levels before chemotherapy. Eva...

journal_title：American journal of nephrology

authors： Brillet G,Deray G,Jacquiaud C,Mignot L,Bunker D,Meillet D,Raymond F,Jacobs C

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:2009 influenza A has spread globally. Respiratory complications and renal failure have been the leading causes for hospitalization and critical illness. We describe the risk factors and complications of acute kidney injury (AKI) in patients with influenza A. METHODS:Observational study of adult patients tes...

journal_title：American journal of nephrology

authors： Demirjian SG,Raina R,Bhimraj A,Navaneethan SD,Gordon SM,Schreiber MJ Jr,Guzman JA

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:While chronic dialysis treatment has been suggested to increase pulmonary pressure values, right ventricular dysfunction (RVD) is a major cause of death in patients with end-stage renal disease. We investigated the impact of different dialysis treatments on right ventricular function. METHODS:We examined 22...

journal_title：American journal of nephrology

authors： Paneni F,Gregori M,Ciavarella GM,Sciarretta S,De Biase L,Marino L,Tocci G,Principe F,Domenici A,Luciani R,Punzo G,Menè P,Volpe M

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Most studies evaluating predictors of renal replacement therapy (RRT) following cardiac surgery use arbitrary defined limits of preoperative serum creatinine. The aim of this study was to evaluate the effect of preoperative renal function using either estimated-glomerular filtration rate (eGFR) derived using...

journal_title：American journal of nephrology

authors： Drosos G,Ampatzidou F,Sarafidis P,Karaiskos T,Madesis A,Boutou AK

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Tacrolimus is mainly metabolized by cytochrome P450 3A5 (CYP3A5), which is expressed in the liver. However, CYP3A5 is also expressed in the kidney tissue and may contribute to local tacrolimus clearance in the kidney allograft. We aimed to evaluate the association between the allograft CYP3A5 genotype and tr...

journal_title：American journal of nephrology

authors： Udomkarnjananun S,Townamchai N,Chariyavilaskul P,Iampenkhae K,Pongpirul K,Sirichindakul B,Panumatrassamee K,Vanichanan J,Avihingsanon Y,Eiam-Ong S,Praditpornsilpa K

更新日期：2018-01-01 00:00:00

abstract：:Clinical and pathologic findings are described in 14 patients whose main abnormality was an excessively thin glomerular basement membrane (GBM). The subjects were aged 11-51 years, the majority males: most were referred because of hematuria, but proteinuria was the main problem in 2, while hypertension or renal functi...

journal_title：American journal of nephrology

authors： Dische FE,Weston MJ,Parsons V

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND/AIMS:Studies have shown that kidney injury molecule-1 (KIM-1) is upregulated in damaged renal proximal tubules. In this study, we examined KIM-1 expression in glomerular epithelial cells in diabetic glomerulopathy. METHODS:Renal histology, immunostaining and Western blot for protein level, and real-time PCR...

journal_title：American journal of nephrology

authors： Zhao X,Zhang Y,Li L,Mann D,Imig JD,Emmett N,Gibbons G,Jin LM

更新日期：2011-01-01 00:00:00