Current State and Future Trends to Optimize the Care of Chronic Kidney Disease in African Americans.

abstract：:Bicarbonate dialysate is claimed to be superior to acetate for both chronic and acute hemodialysis. We compared acetate and bicarbonate dialysates in 30 acute renal failure patients during 120 dialyses. 4 patients were diabetic and 2 had liver failure. Patients were dialyzed alternating acetate and bicarbonate dialysa...

journal_title：American journal of nephrology

authors： Borges HF,Fryd DS,Rosa AA,Kjellstrand CM

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND/AIMS:Epithelial-to-mesenchymal cell transformation (EMT) is the trans-differentiation of tubular epithelial cells into myofibroblasts, an event underlying progressive chronic kidney disease in diabetes, resulting in fibrosis. Mainly reported in proximal regions of the kidney, EMT is now recognized as a key c...

journal_title：American journal of nephrology

authors： Hills CE,Squires PE

更新日期：2010-01-01 00:00:00

abstract：:The development of new therapies for chronic diseases, such as diabetic kidney disease (DKD), will continue to be hampered by lack of sufficient biomarkers that will provide insights and will be responsive to treatment interventions. The recent application of metabolomic technologies, such as nuclear magnetic resonanc...

journal_title：American journal of nephrology

authors： Darshi M,Van Espen B,Sharma K

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIM:Although clinical and immunological findings in steroid-sensitive nephrotic syndrome (SSNS) favor an immunopathogenesis, many issues remain unsolved. Comprehensive studies analyzing cellular and humoral immunity in SSNS are scarce, and few studies addressed the effect of steroids on immunological factors...

journal_title：American journal of nephrology

authors： Kemper MJ,Zepf K,Klaassen I,Link A,Muller-Wiefel DE

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:To evaluate the association of dialysate interleukin-6 (IL-6), a marker of ongoing peritoneal inflammation, with the alteration of peritoneal solute transport rate (PSTR) in continuous ambulatory peritoneal dialysis (CAPD) patients. METHODS:Stable CAPD patients were enrolled in the present study. A total of...

journal_title：American journal of nephrology

authors： Yang X,Zhang H,Hang Y,Yan H,Lin A,Huang J,Ni Z,Qian J,Fang W

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Although rhabdomyolysis has been associated with acute kidney injury and mortality in the short term, the long-term consequences of an episode of rhabdomyolysis remain unknown. We sought to identify the long-term outcomes of rhabdomyolysis, including mortality, renal function, and incidence of hypertension (...

journal_title：American journal of nephrology

authors： Faulk T,Walker LE,Howard JT,Janak JC,Sosnov JA,Stewart IJ

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Health-related quality of life (HRQOL) reflects a patient's perceived disease burden, treatment effectiveness, and health status. Given the time burden and physiologic effects of hemodialysis, patients who spend dialysis time (9-15 h/week) physically or intellectually engaged may have better HRQOL. We charac...

journal_title：American journal of nephrology

authors： Warsame F,Ying H,Haugen CE,Thomas AG,Crews DC,Shafi T,Jaar B,Chu NM,Segev DL,McAdams-DeMarco MA

更新日期：2018-01-01 00:00:00

abstract：:Alcaligenes xylosoxidans is an uncommon cause of peritonitis in patients on maintenance continuous ambulatory peritoneal dialysis (CAPD). Peritonitis caused by A. xylosoxidans usually carries a poor prognosis because of the pathogen's virulence and its universal resistance to most antimicrobial agents. Even after earl...

journal_title：American journal of nephrology

authors： Tang S,Cheng CC,Tse KC,Li FK,Choy BY,Chan TM,Lai KN

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND/AIMS:Patients on chronic hemodialysis have a high prevalence of heart disease and poor self-reported physical function. The association between structural heart disease and self-reported physical function in patients on hemodialysis is unknown. METHODS:We studied the association between elevated pulmonary a...

journal_title：American journal of nephrology

authors： Abreo AP,Herzog CA,Kutner NG,Lea J,Johansen KL

更新日期：2015-01-01 00:00:00

abstract：UNLABELLED:Although it is anticipated that most patients with renal insufficiency will progress towards end-stage renal disease (ESRD) there have been few population-based studies to validate this assumption. We examined serial creatinines from 3,874 anonymous patients at an urban VA medical center who had a baseline c...

journal_title：American journal of nephrology

authors： Fink JC,Salmanullah M,Blahut SA,Weir MR,Sawyer R,Henrich WL,Hise MK

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:C-reactive protein (CRP), which reflects chronic inflammation, is a strong predictor of cardiovascular mortality in hemodialysis patients. We investigated whether persistent elevation of CRP is associated with cardiac function and morphology in patients maintained on hemodialysis. METHODS:Predialysis high-s...

journal_title：American journal of nephrology

authors： Kim BS,Jeon DS,Shin MJ,Kim YO,Song HC,Lee SH,Kim SY,Choi EJ,Chang YS,Bang BK

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Steroid therapy has become an effective option for patients with primary Sjogren's syndrome with tubulointerstitial nephritis (TIN), while the use of cytotoxic agents is still debated. Our study aimed to compare the clinical outcomes of patients treated with cyclophosphamide (CTX) combined with glucocorticoi...

journal_title：American journal of nephrology

authors： Shen Y,Xie J,Lin L,Li X,Shen P,Pan X,Ren H,Chen N

更新日期：2017-01-01 00:00:00

abstract：:The use of Dacron cuff double-lumen permanent catheters for hemodialysis has become more common in the dialysis unit as patients await for creation or maturation of a permanent hemoaccess for various reasons. Placement of these catheters is often done by surgeons. Nephrologists skilled in the placement of temporary ce...

journal_title：American journal of nephrology

authors： Choudhury D,Ahmed Z,Girgis HI,Kronfli S

更新日期：1999-01-01 00:00:00

abstract：:The terminal complement-inhibitor eculizumab has dramatically changed the management of patients with atypical hemolytic uremic syndrome (aHUS), and has also shown promise for treating certain forms of secondary HUS (sHUS), including that caused by drugs and solid-organ/hematopoietic stem cell transplant. While effect...

journal_title：American journal of nephrology

authors： Olson SR,Lu E,Sulpizio E,Shatzel JJ,Rueda JF,DeLoughery TG

更新日期：2018-01-01 00:00:00

abstract：:Autopsy reports on 155 successive end-stage renal disease (ESRD) patients and 147 control patients without ESRD, matched for age, race and gender, were collected. Cystic transformation of the kidneys was noted in 58% of the ESRD patients and 13.6% of the control patients. There were 25 ESRD patients with renal adenoma...

journal_title：American journal of nephrology

authors： Miller LR,Soffer O,Nassar VH,Kutner MH

更新日期：1989-01-01 00:00:00

abstract：:Chronic kidney disease affects approximately 10% of the world's adult population: it is within the top 20 causes of death worldwide, and its impact on patients and their families can be devastating. World Kidney Day and International Women's Day in 2018 coincide, thus offering an opportunity to reflect on the importan...

journal_title：American journal of nephrology

authors： Piccoli GB,Alrukhaimi M,Liu ZH,Zakharova E,Levin A,World Kidney Day Steering Committee.

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Detection of chronic kidney disease (CKD) with urine albumin-to-creatinine ratio (UACR) among patients with hypertension (HTN) provides an opportunity for early treatment, potentially mitigating risk of CKD progression and cardiovascular complications. Differences in UACR testing patterns among racial/ethnic...

journal_title：American journal of nephrology

authors： Lee J,Chu C,Guzman D,Fontil V,Velasquez A,Powe NR,Tuot DS

更新日期：2019-01-01 00:00:00

abstract：:We report on a Mycobacterium marinum infection in a diabetic woman 8 years after undergoing a combined pancreas-kidney transplantation. This is, to our knowledge, the first case report on an isolated skin infection with atypical mycobacteria after simultaneous pancreas-kidney transplantation. A genetic probe categoriz...

journal_title：American journal of nephrology

authors： Schmekal B,Janko O,Zazgornik J,Schinko H,Bogner S,Syre G,Biesenbach G

更新日期：2002-09-01 00:00:00

abstract：:The current study focused on the effect of continuous ambulatory peritoneal dialysis (CAPD) dialysate obtained following different intraperitoneal dwell periods on the release of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF alpha) from mononuclear leukocytes (PBMC). Aliquots of 5 x 10(6)/ml healthy periph...

journal_title：American journal of nephrology

authors： Jörres A,Topley N,Steenweg L,Müller C,Köttgen E,Gahl GM

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Despite a previous study showing that PINCH-1 exerts an important role in regulating TGF-β1-mediated mesenchymal transition through its interaction with integrin-linked kinase, relatively little is known about the role of PINCH in the obstructive nephropathy. METHODS:To construct a rat model of renal inters...

journal_title：American journal of nephrology

authors： Jia L,Li X,Gu Y,Cui W

更新日期：2016-01-01 00:00:00

abstract：:Hemolytic-uremic syndrome following quinine ingestion is a newly described phenomenon, with just two previous descriptions of 4 cases in the literature. We describe a 5th case. The reaction may be mediated by the presence of antibodies reactive against platelets in the presence of quinine. Treatment has included use o...

journal_title：American journal of nephrology

authors： Hagley MT,Hosney IA,Hulisz DT,Davis HH

更新日期：1992-01-01 00:00:00

abstract：:The relationship of the duration of anuria to the recovery in glomerular filtration rate (GFR) was studied in 71 children with diarrhea-associated hemolytic uremic syndrome. A significant relationship was found, and regression analysis revealed that y = 114.61 - 5.68 x, where y is predicted GFR (ml/min/1.73 m2) and x ...

journal_title：American journal of nephrology

authors： Robson WL,Leung AK,Brant R

更新日期：1993-01-01 00:00:00

abstract：:We assessed blood volume (BV) in 20 edematous patients with nephrotic syndrome and in 32 subjects without renal or other disease liable to induce BV variation. Two methods were chosen, one using 131I-albumin and the other 51Cr red blood cells. Among the 20 patients, 11 presented minimal-change lesions, and 9 had histo...

journal_title：American journal of nephrology

authors： Olmer M,Berland Y,Purgus R,Schultz G

更新日期：1989-01-01 00:00:00

abstract：:Radioisotopic methods for the determination of the glomerular filtration rate (GFR) are highly accurate but require the collection of multiple blood and urine samples and are costly to perform due to personnel, material, and analysis costs. Nonradioactive methods of GFR determination have the potential of minimizing p...

journal_title：American journal of nephrology

authors： Rocco MV,Buckalew VM Jr,Moore LC,Shihabi ZK

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND/AIMS:Although HIV-infected persons are at higher risk for acute kidney injury (AKI) during hospitalization compared with their uninfected counterparts, risk factors for AKI are not well-defined. We aimed to describe the evolving incidence of AKI among HIV-infected individuals and to identify important AKI ri...

journal_title：American journal of nephrology

authors： Li Y,Shlipak MG,Grunfeld C,Choi AI

更新日期：2012-01-01 00:00:00

abstract：:We studied plasma, dialysate, and muscle carnitine levels in patients with stable chronic renal failure on hemodialysis, and intermittent peritoneal, or continuous ambulatory peritoneal dialysis (CAPD). In patients on hemodialysis, plasma carnitine levels fell from 46.2 +/- 4.5 mumol/l (mean +/- SEM) to 18.8 +/- 2.7 m...

journal_title：American journal of nephrology

authors： Moorthy AV,Rosenblum M,Rajaram R,Shug AL

更新日期：1983-07-01 00:00:00

abstract：AIMS:Although there are plenty of data about the differences in left ventricular tissue Doppler (TD) velocities by preload reduction, only a few studies regarding right ventricular function are found in the literature. We investigated the effect of intravascular volume reduction on right ventricular function by ultrafi...

journal_title：American journal of nephrology

authors： Arinc H,Gunduz H,Tamer A,Ozhan H,Akdemir R,Saglam H,Oguzhan A,Uyan C

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Aldosterone plays an important role in fibrosis. Recent studies showed that Na(+)-H(+) exchanger isoform 1 (NHE1) is involved in mineralocorticoid-induced organ fibrosis. In this study, we examined the role of NHE1 in aldosterone-induced fibronectin accumulation in rat mesangial cells and the signaling pathw...

journal_title：American journal of nephrology

authors： Zhang M,Chen J,Lai L,You L,Lin S,Hao C,Gu Y

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Malnutrition-inflammation score (MIS) is a comprehensive and quantitative system to assess malnutrition-inflammation complex syndrome, and a strong correlation between MIS and morbidity/mortality in maintenance hemodialysis (MHD) patients had been demonstrated. However, there is no cut-off value of MIS to ca...

journal_title：American journal of nephrology

authors： Ho LC,Wang HH,Peng YS,Chiang CK,Huang JW,Hung KY,Hu FC,Wu KD

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND/AIMS:A recent study suggests that inflammation and malnutrition are strongly associated with cardiovascular disease in dialysis patients. Endothelial lipase (EL) is a newly cloned physiological regulator of high-density lipoprotein cholesterol (HDL), which is associated with the progression of atherosclerosi...

journal_title：American journal of nephrology

authors： Fujii H,Fukuda A,Tanaka M,Kojima Y,Ishida T,Hirata K,Fukagawa M

更新日期：2008-01-01 00:00:00