The emerging role of vascular smooth muscle cell apoptosis in atherosclerosis and plaque stability.

abstract：:To evaluate the significance of tubulointerstitial lesions in the cortical area of renal biopsy specimens, clinicopathological studies were performed on 101 cases of IgA nephropathy, 31 cases of IgA-negative (non-IgA) proliferative glomerulonephritis and 75 cases of idiopathic membranous glomerulonephritis. The degree...

journal_title：American journal of nephrology

authors： Abe S,Amagasaki Y,Iyori S,Konishi K,Kato E,Sakaguchi H

更新日期：1989-01-01 00:00:00

abstract：:In this paper, we analyze the collection of ancient Greek treatises ascribed to Hippocrates (460; between 371 and 350 BC), in order to determine whether or not edema can be traced. As a result of reading these works on the Greek text, we recognize some symptoms of edema in those called oidêma (swelling) and udrôps (dr...

journal_title：American journal of nephrology

authors： Touwaide A,De Santo NG

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:There is continued and significant debate regarding the salient etiologies associated with graft loss and racial disparities in kidney transplant recipients. METHODS:This was a longitudinal cohort study of all adult kidney transplant recipients, comparing patients with early graft loss (<5 years) to those w...

journal_title：American journal of nephrology

authors： Taber DJ,Douglass K,Srinivas T,McGillicuddy JW,Bratton CF,Chavin KD,Baliga PK,Egede LE

更新日期：2014-01-01 00:00:00

abstract：:Resistance to the action of PTH is encountered in chronic renal failure (CRF). This was attributed to downregulation of PTH receptor due to the state of secondary hyperparathyroidism of CRF. The present study examined whether the amount of PTH-PTH-related peptide (PTH-PTHrP) mRNA in a traditional (kidney) and a nontra...

journal_title：American journal of nephrology

authors： Tian J,Smogorzewski M,Kedes L,Massry SG

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:The impact of socioeconomic factors on arteriovenous fistula (AVF) creation in hemodialysis (HD) patients is not well understood. We assessed the association of area and individual-level indicators of poverty and health care insurance on AVF use among incident end-stage renal disease (ESRD) patients initiate...

journal_title：American journal of nephrology

authors： Nee R,Moon DS,Jindal RM,Hurst FP,Yuan CM,Agodoa LY,Abbott KC

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The optimal level of serum ferritin (s-ft) for anemia control and good survival in hemodialysis (HD) patients remains unclear. A 10-year survey was performed to clarify the appropriate quantities of s-ft and investigate the relationships among s-ft, transferrin saturation (TSAT), and mortality in HD patients...

journal_title：American journal of nephrology

authors： Ogawa C,Tsuchiya K,Kanda F,Maeda T

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:In the US, native kidney biopsies are usually inpatient procedures. We developed an outpatient biopsy protocol for low-risk patients and assessed its safety and efficacy. METHODS:Patients with an SBP <140 mm Hg and a BMI ≤35 who were not taking anticoagulants, ASA and NSAIDS in the preceding week were inclu...

journal_title：American journal of nephrology

authors： McMahon GM,McGovern ME,Bijol V,Benson CB,Foley R,Munkley K,Schnipper J,Franz C,Lin J

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:Although HIV-infected persons are at higher risk for acute kidney injury (AKI) during hospitalization compared with their uninfected counterparts, risk factors for AKI are not well-defined. We aimed to describe the evolving incidence of AKI among HIV-infected individuals and to identify important AKI ri...

journal_title：American journal of nephrology

authors： Li Y,Shlipak MG,Grunfeld C,Choi AI

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:To evaluate the association of dialysate interleukin-6 (IL-6), a marker of ongoing peritoneal inflammation, with the alteration of peritoneal solute transport rate (PSTR) in continuous ambulatory peritoneal dialysis (CAPD) patients. METHODS:Stable CAPD patients were enrolled in the present study. A total of...

journal_title：American journal of nephrology

authors： Yang X,Zhang H,Hang Y,Yan H,Lin A,Huang J,Ni Z,Qian J,Fang W

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Clinical indicators for accurately distinguishing diabetic nephropathy (DN) from non-diabetic renal disease in type 2 diabetes (T2D) are lacking. This study aimed to develop and validate a nomogram for predicting DN in T2D patients with kidney disease. METHODS:A total of 302 consecutive patients with T2D wh...

journal_title：American journal of nephrology

authors： Jiang S,Fang J,Yu T,Liu L,Zou G,Gao H,Zhuo L,Li W

更新日期：2020-01-01 00:00:00

abstract：:A quantitative scoring method was designed to assess the extent of muscle damage. Technetium-99m pyrophosphate (99mTc-PYP) scintigraphy was performed for 9 patients experiencing crush injury in the Chichi (Taiwan) earthquake. The magnitude of muscle uptake of 99mTc-PYP was graded as follows: grade 0, less than bone ra...

journal_title：American journal of nephrology

authors： Chang HR,Kao CH,Lian JD,Shu KH,Cheng CH,Wu MJ,Chen CH

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND/AIMS:Studies have shown that kidney injury molecule-1 (KIM-1) is upregulated in damaged renal proximal tubules. In this study, we examined KIM-1 expression in glomerular epithelial cells in diabetic glomerulopathy. METHODS:Renal histology, immunostaining and Western blot for protein level, and real-time PCR...

journal_title：American journal of nephrology

authors： Zhao X,Zhang Y,Li L,Mann D,Imig JD,Emmett N,Gibbons G,Jin LM

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Elevated osteoprotegerin (OPG) levels are inversely correlated with creatinine clearance and end-stage renal disease in patients with diabetes, however its role in predicting decline in renal function and progression to a more advanced stage disease in the elderly general population is unknown. METHODS:This...

journal_title：American journal of nephrology

authors： Lewis JR,Lim WH,Zhu K,Wong G,Dhaliwal SS,Lim EM,Ueland T,Bollerslev J,Prince RL

更新日期：2014-01-01 00:00:00

abstract：:Vascular access thrombosis is more common with polytetrafluoroethylene (PTFE) grafts than with native arteriovenous fistulae (AVF). Recent studies report an unexplained excess vascular access morbidity in women on hemodialysis. We studied 92 consecutive end-stage renal disease (ESRD) patients receiving their first per...

journal_title：American journal of nephrology

authors： Ifudu O,Macey LJ,Homel P,Hyppolite JC,Hong J,Sumrani N,Distant D,Sommer BG,Friedman EA

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Previous studies on end-of-life (EOL) care among patients with chronic kidney disease (CKD) have been largely limited to White hemodialysis patients. In this study, we sought to explore racial variability in EOL communication, care preferences and advance care planning (ACP) among patients with advanced CKD ...

journal_title：American journal of nephrology

authors： Eneanya ND,Wenger JB,Waite K,Crittenden S,Hazar DB,Volandes A,Temel JS,Thadhani R,Paasche-Orlow MK

更新日期：2016-01-01 00:00:00

abstract：:Hyperlipidemia is common in patients with glomerular proteinuria. It may contribute to atherosclerotic complications and accelerate glomerular damage. Early trials of the fibric acid derivative clofibrate led to a myositis syndrome causing many nephrologists to abandon attempts at treatment of nephrotic hyperlipidemia...

journal_title：American journal of nephrology

authors： Appel GB,Appel AS

更新日期：1990-01-01 00:00:00

abstract：:The medical history of salt begins in ancient times and is closely related to different aspects of human history. Salt may be extracted from sea water, mineral deposits, surface encrustations, saline lakes and brine springs. In many inland areas, wood was used as a fuel source for evaporation of brine and this practic...

journal_title：American journal of nephrology

authors： Cirillo M,Capasso G,Di Leo VA,De Santo NG

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND/AIMS:Chronic kidney disease (CKD) and serious mental illness (SMI) are both associated with an increased risk for repeated hospitalization. The objective of this study was to determine if co-occurring SMI exacerbates the risk for subsequent hospitalization, particularly through the emergency department (ED),...

journal_title：American journal of nephrology

authors： McPherson S,Barbosa-Leiker C,Daratha K,Short R,McDonell MG,Alicic R,Roll J,Tuttle K

更新日期：2014-01-01 00:00:00

abstract：:In hypoaldosteronemic patients with chronic renal insufficiency, administration of a mineralocorticoid steroid such as fludrocortisone can ameliorate hyperkalemia and metabolic acidosis, but this therapy is not always safe owing to the deleterious consequences of extracellular fluid volume expansion resulting from min...

journal_title：American journal of nephrology

authors： Sebastian A,Schambelan M,Sutton JM

更新日期：1984-01-01 00:00:00

abstract：:This report reviews the features of 149 cases of renal allograft rupture, while adding a detailed description of 3 more cases to the English literature. From November, 1973 to November, 1979, 3 cases of renal allograft rupture occurred in 100 renal transplants performed at Research Medical Center, Kansas City, Mo., an...

journal_title：American journal of nephrology

authors： Thukral R,Mir AR,Jacobson MP

更新日期：1982-01-01 00:00:00

abstract：:The pathogenesis of calciphylaxis, a potentially life-threatening condition, is not well understood. Several factors such as end-stage renal disease (azotemia), hyperparathyroidism, hyperphosphatemia, hypercalcemia, a high calcium-phosphate product, and the use of steroids and cytotoxic drugs after kidney transplantat...

journal_title：American journal of nephrology

authors： Rudwaleit M,Schwarz A,Trautmann C,Offermann G,Distler A

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND/AIMS:Intradialytic hypotension is the most common complication of modern day haemodialysis (HD). Convective modalities, including haemodiafiltration (HDF) are reported to result in greater cardiovascular stability compared to standard HD, which has been suggested to be due to improved solute transport betwee...

journal_title：American journal of nephrology

authors： Kumar S,Khosravi M,Massart A,Potluri M,Davenport A

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND/AIMS:Insulin is synthesised as a pro-hormone with an interconnecting C-peptide, cleaved during post-translational modification. This review discusses growing evidence which indicates that C-peptide is biologically active, benefiting microvascular complications associated with diabetes. METHODS:To explore th...

journal_title：American journal of nephrology

authors： Hills CE,Brunskill NJ,Squires PE

更新日期：2010-01-01 00:00:00

abstract：:A patient with progressive systemic sclerosis (PSS) involving skin, digit, esophagus, and lung developed the nephrotic syndrome and rapidly progressive renal insufficiency. Renal pathology revealed capillary collapse, cellular crescents, arteriolar hyaline deposition, and mesangial proliferation. On immunofluorescence...

journal_title：American journal of nephrology

authors： Eiser AR,Zilversmit R,Neff MS,Grishman E,Slifkin RF

更新日期：1986-01-01 00:00:00

abstract：:The use of Dacron cuff double-lumen permanent catheters for hemodialysis has become more common in the dialysis unit as patients await for creation or maturation of a permanent hemoaccess for various reasons. Placement of these catheters is often done by surgeons. Nephrologists skilled in the placement of temporary ce...

journal_title：American journal of nephrology

authors： Choudhury D,Ahmed Z,Girgis HI,Kronfli S

更新日期：1999-01-01 00:00:00

abstract：:Shortage of kidney donor is still a major limitation for renal transplantation programs. This review focuses on the emerging practices, adopted to increase transplant activities, of expanding the criteria for donor and recipient selection without exposing the recipient to the drawbacks of a graft with inadequate nephr...

journal_title：American journal of nephrology

authors： Perico N,Ruggenenti P,Scalamogna M,Remuzzi G

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND/AIMS:Vitamin D insufficiency drives secondary hyperparathyroidism (SHPT) and is associated with increased cardiovascular mortality in patients with chronic kidney disease (CKD). SHPT is poorly addressed by current vitamin D repletion options. The present study evaluated a novel investigational vitamin D repl...

journal_title：American journal of nephrology

authors： Sprague SM,Silva AL,Al-Saghir F,Damle R,Tabash SP,Petkovich M,Messner EJ,White JA,Melnick JZ,Bishop CW

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Three million people in the United States are estimated to have chronic kidney disease (CKD). Management of these CKD patients in the outpatient primary care clinic setting has not been well studied. HYPOTHESIS:Primary care management of CKD can be assessed and opportunities for improvement can be identifie...

journal_title：American journal of nephrology

authors： Israni A,Korzelius C,Townsend R,Mesler D

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND/AIMS:We previously reported that patients with chronic kidney disease (CKD) receiving warfarin therapy and whose international normalized ratio increases to >3.0 may develop acute kidney injury (AKI) as a result of glomerular hemorrhage and formation of obstructive red blood cell (RBC) casts. We named this c...

journal_title：American journal of nephrology

authors： Ozcan A,Ware K,Calomeni E,Nadasdy T,Forbes R,Satoskar AA,Nadasdy G,Rovin BH,Hebert LA,Brodsky SV

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:Advanced glycation end products (AGEs) induce epithelial mesenchymal transition (EMT) in renal proximal tubular epithelial cells (PTECs) by promoting the two EMT regulators, transforming growth factor beta (TGF-β) and connective tissue growth factor (CTGF). However, the exact signaling mechanism remains...

journal_title：American journal of nephrology

authors： Cheng M,Liu H,Zhang D,Liu Y,Wang C,Liu F,Chen J

更新日期：2015-01-01 00:00:00