Pathophysiology of spasticity: implications for neurorehabilitation.

abstract：:Despite being identified as a high risk cohort for psychosis, there has been relatively little research on the clinical presentation and assessment of Schizotypal Personality Disorder (SPD) in childhood. The current study aimed to develop a measure of childhood SPD (Melbourne Assessment of Schizotypy in Kids (MASK)) a...

journal_title：BioMed research international

authors： Jones HP,Testa RR,Ross N,Seal ML,Pantelis C,Tonge B

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To evaluate the role of nutritional factors, serum lipids, and lipoproteins in late age-related macular degeneration (late AMD). METHODS:Intake of red meat, fruit, fish, vegetables, and alcohol, smoking status, and body mass index (BMI) were ascertained questionnaire-based in 1147 late AMD cases and 1773 contr...

journal_title：BioMed research international

authors： Ersoy L,Ristau T,Lechanteur YT,Hahn M,Hoyng CB,Kirchhof B,den Hollander AI,Fauser S

更新日期：2014-01-01 00:00:00

abstract：:The complete chloroplast genome of J. flava, an endangered medicinal plant in Saudi Arabia, was sequenced and compared with cp genome of three Acanthaceae species to characterize the cp genome, identify SSRs, and also detect variation among the cp genomes of the sampled Acanthaceae. NOVOPlasty was used to assemble the...

journal_title：BioMed research international

authors： Yaradua SS,Alzahrani DA,Albokhary EJ,Abba A,Bello A

更新日期：2019-08-06 00:00:00

abstract：:Different opinions exist on the relationship between the C-reactive protein-to-albumin ratio (CAR) and the prognosis of colon cancer. This study is aimed at evaluating the relationship between CAR and prognosis of stage II-III colon cancer and establishing a clinical prognosis model. Patients were randomised to a trai...

journal_title：BioMed research international

authors： Xu Y,Liang F,Chen Y,Wang Z,Zhong H,Tang W

更新日期：2020-11-22 00:00:00

abstract：:This study aimed to summarize the clinical features, diagnosis, and treatment of Chiari malformation type I- (CM-1-) associated syringobulbia. We performed a literature review of CM-1-associated syringobulbia in PubMed, Ovid MEDLINE, and Web of Science databases. Our concerns were the clinical features, radiologic pre...

journal_title：BioMed research international

authors： Shen J,Shen J,Huang K,Wu Y,Pan J,Zhan R

更新日期：2019-03-19 00:00:00

abstract：:Traumatic brain injury (TBI) leads to important and deleterious neuroinflammation, as evidenced by indicators such as edema, cytokine production, induction of nitric oxide synthase, and leukocyte infiltration. After TBI, cerebral vascular endothelial cells play a crucial role in the pathogenesis of inflammation. In ou...

journal_title：BioMed research international

authors： Wang KW,Wang HK,Chen HJ,Liliang PC,Liang CL,Tsai YD,Cho CL,Lu K

更新日期：2014-01-01 00:00:00

abstract：:Fibroblast growth factor 21 (FGF21) is a metabolic hormone with multiple beneficial effects on lipid and glucose homeostasis. Previous study demonstrated that FGF21 might be one of the Sp1 target genes. However, the transcriptional role of Sp1 on FGF21 in adipose tissue and liver has not been reported. In this study, ...

journal_title：BioMed research international

authors： Chen S,Li H,Zhang J,Jiang S,Zhang M,Xu Y,Dong K,Yang Y,Fang Q,Jia W

更新日期：2017-01-01 00:00:00

abstract：:The total knee arthroplasty (TKA) is the gold standard for patients with an advanced symptomatic gonarthrosis. However, there are very few publications dealing with the primary TKA for patients with a proximal tibia fracture. In our retrospective study we evaluated 30 patients treated with a TKA for a proximal tibia f...

journal_title：BioMed research international

authors： Haufe T,Förch S,Müller P,Plath J,Mayr E

更新日期：2016-01-01 00:00:00

abstract：:Densitometry data generated for Western blots are commonly used to compare protein abundance between samples. In the last decade, it has become apparent that assumptions underpinning these comparisons are often violated in studies reporting Western blot data in the literature. These violations can lead to erroneous in...

journal_title：BioMed research international

authors： Butler TAJ,Paul JW,Chan EC,Smith R,Tolosa JM

更新日期：2019-01-21 00:00:00

abstract：:Integrin αIIbβ3 plays a crucial role in the process of platelet aggregation. Three integrin αIIbβ3 antagonists (abciximab, eptifibatide, and tirofiban) have been approved by FDA for clinical use. Unfortunately, they all showed severe side effects such as thrombocytopenia and bleeding risk. Thus, researches on the deve...

journal_title：BioMed research international

authors： Ding X,Liu TD,Xie ZL,Zhao Q,Cao Y,Liu XD,Wang CH,Gamariel RR,Ming X,Li ZY,Kong Y

更新日期：2016-01-01 00:00:00

abstract：:There is a need to scientifically validate the claim that wild species of medicinal plants are more potent than the cultivated plants. Thus, this study evaluated the phytochemical and antioxidant properties of wild and cultivated Alepidea amatymbica. Acetone, methanol, and water extracts of the rhizome of wild and cul...

journal_title：BioMed research international

authors： Mangoale RM,Afolayan AJ

更新日期：2020-04-13 00:00:00

abstract：Introduction:The aim of the study was to analyze which variables influenced the completion of a cold loop hysteroscopic myomectomy in a one-step procedure in a large cohort of patients. Materials and Methods:A retrospective cohort study of 1434 cold loop resectoscopic myomectomies consecutively performed. The study po...

journal_title：BioMed research international

authors： Mazzon I,Favilli A,Grasso M,Horvath S,Bini V,Di Renzo GC,Gerli S

更新日期：2018-05-20 00:00:00

abstract：:Metastasis is the leading cause of lung cancer-associated death. Downregulated expression of E-cadherin followed by epithelial-mesenchymal transition (EMT) is critical for metastasis initiation in lung cancer. BTBD7 plays essential roles in lung cancer metastasis, but the mechanisms remain unknown. This study aimed to...

journal_title：BioMed research international

authors： Shu J,Wang L,Han F,Chen Y,Wang S,Luo F

更新日期：2019-11-27 00:00:00

abstract：:28 new pyrrolidine types of compounds as analogues for natural polyhydroxy alkaloids of codonopsinine were evaluated for their anti-MRSA activity using MIC and MBC value determination assay against a panel of S. aureus isolates. One pyrrolidine compound, MFM 501, exhibited good inhibitory activity with MIC value of 15...

journal_title：BioMed research international

authors： Johari SA,Mohtar M,Mohammad SA,Sahdan R,Shaameri Z,Hamzah AS,Mohammat MF

更新日期：2015-01-01 00:00:00

abstract：Background/Aims:The molecular mechanism of dormancy initiation of cancer stem cells (CSCs) is not clear. This study was to explore the molecular mechanism by which CSCs switch from mitotic division to quiescence. Methods:MTT assays, flow cytometry, Western blotting, qRT-PCR, and immunofluorescence staining were used t...

journal_title：BioMed research international

authors： Zhang W,Ren Z,Jia L,Li X,Jia X,Han Y

更新日期：2019-08-25 00:00:00

abstract：:Eccentric exercise is characterized by initial unfavorable effects such as subcellular muscle damage, pain, reduced fiber excitability, and initial muscle weakness. However, stretch combined with overload, as in eccentric contractions, is an effective stimulus for inducing physiological and neural adaptations to train...

journal_title：BioMed research international

authors： Hedayatpour N,Falla D

更新日期：2015-01-01 00:00:00

abstract：:Slaughterhouse work involves a high degree of repetitive and forceful upper limb movements and thus implies an elevated risk of work-related musculoskeletal disorders. High intensity strength training effectively rehabilitates musculoskeletal disorders among sedentary employees, but less is known about the effect amon...

journal_title：BioMed research international

authors： Sundstrup E,Jakobsen MD,Jay K,Brandt M,Andersen LL

更新日期：2014-01-01 00:00:00

abstract：:Revealing the gene regulation networks governing cancer initiation and development is necessary while it remains uncompleted. In recent years, enhancers have been reported to be widely transcribed, resulting in the generation of enhancer RNAs (eRNAs). Previous studies have reported that eRNAs are a subclass of long no...

journal_title：BioMed research international

authors： Liu Y,Ding M,Gao Q,He A,Liu Y,Mei H

更新日期：2018-05-22 00:00:00

abstract：:Almost forty years ago, it was first hypothesized that an increased dietary intake of omega-3 polyunsaturated fatty acids (PUFA) from fish fat could exert protective effects against several pathologies. Decades of intense preclinical investigation have supported this hypothesis in a variety of model systems. Several c...

journal_title：BioMed research international

authors： Weylandt KH,Serini S,Chen YQ,Su HM,Lim K,Cittadini A,Calviello G

更新日期：2015-01-01 00:00:00

abstract：:We developed a new product called titanium-prepared platelet-rich fibrin (T-PRF). The T-PRF method is based on the hypothesis that titanium may be more effective in activating platelets than the silica activators used with glass tubes in Chouckroun's leukocyte- and platelet-rich fibrin (L-PRF) method. In this study, w...

journal_title：BioMed research international

authors： Tunalı M,Özdemir H,Küçükodacı Z,Akman S,Yaprak E,Toker H,Fıratlı E

更新日期：2014-01-01 00:00:00

abstract：:Postprandial metabolic response depends on the meals' components and can be different in normal weight and obese people. However, there are some discrepancies between various reports. The aim of this study was to determine the metabolic response after intake of standardised meals with various fat and carbohydrate cont...

journal_title：BioMed research international

authors： Adamska E,Ostrowska L,Gościk J,Waszczeniuk M,Krętowski A,Górska M

更新日期：2015-01-01 00:00:00

abstract：:The exosomes are derived from mesenchymal stem cells (MSCs) and may be potentially used as an alternative for cell therapy, for treating diabetic wounds, and aid in angiogenesis. This study, aimed to investigate whether exosomes originated from bone marrow-derived MSCs (BMSCs) preconditioned by deferoxamine (DFO-Exos)...

journal_title：BioMed research international

authors： Ding J,Wang X,Chen B,Zhang J,Xu J

更新日期：2019-05-05 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is the most prevalent form of oral cancer. Inducible nitric oxide synthase (iNOS) and p53 are associated with a variety of human cancers, but their expression and interaction in OSCC have not been fully explored. In this study, we investigated the expression of iNOS and p53 in OSCC ...

journal_title：BioMed research international

authors： Yang L,Wang Y,Guo L,Wang L,Chen W,Shi B

更新日期：2015-01-01 00:00:00

abstract：Objective:The NOCTURNIN gene links nutrient absorption and metabolism to the circadian clock. Shift workers are at a heightened risk of overweight and of developing obesity and metabolic syndrome. This study investigates the diurnal variation of NOCTURNIN in healthy volunteers and its expression levels in rotational sh...

journal_title：BioMed research international

authors： Bracci M,Copertaro A,Ciarapica V,Barbaresi M,Esposito S,Albanesi A,Valentino M,Ledda C,Rapisarda V,Santarelli L

更新日期：2019-07-31 00:00:00

abstract：:Recent studies have shown that sumoylation is a posttranslational modification involved in regulation of the transforming growth factor-β (TGF-β) signaling pathway, which plays a critical role in renal fibrosis in diabetic nephropathy (DN). However, the role of sumoylation in the regulation of TGF-β signaling in DN is...

journal_title：BioMed research international

authors： Zhou X,Gao C,Huang W,Yang M,Chen G,Jiang L,Gou F,Feng H,Ai N,Xu Y

更新日期：2014-01-01 00:00:00

abstract：:We encapsulated tumor necrosis factor-α (TNF-α), a major proinflammatory cytokine, into cholesteryl pullulan (CHP) to prepare TNF/CHP nanoparticles. In this report, we describe the immune-enhancing capability of the nanoparticles to act as a vaccine adjuvant. TNF/CHP nanoparticles showed excellent storage stability an...

journal_title：BioMed research international

authors： Nagatomo D,Taniai M,Ariyasu H,Taniguchi M,Aga M,Ariyasu T,Ohta T,Fukuda S

更新日期：2015-01-01 00:00:00

abstract：:Rhabdoid tumor of the kidney (RTK) is a rare and severely malignant tumor occurring in infancy and early childhood, with the overall outcomes remain poor. Neither gene regulatory networks nor biomarkers to predict the prognostic outcomes have been elucidated in RTK. In this study, RNA sequencing data were obtained to ...

journal_title：BioMed research international

authors： Wang X,Wu X,Li T,Cui M,Zhu L,Wang G,Guo F

更新日期：2020-08-26 00:00:00

abstract：:Obesity or maternal overnutrition during pregnancy and lactation might have long-term consequences in offspring health. Fetal programming is characterized by adaptive responses to specific environmental conditions during early life stages. Programming alters gene expression through epigenetic modifications leading to ...

journal_title：BioMed research international

authors： Montalvo-Martínez L,Maldonado-Ruiz R,Cárdenas-Tueme M,Reséndez-Pérez D,Camacho A

更新日期：2018-06-20 00:00:00

abstract：:Di-2-ethylhexyl phthalate (DEHP) is extensively used as a plasticizer in many products, especially medical devices, furniture materials, cosmetics, and personal care products. DEHP is noncovalently bound to plastics, and therefore, it will leach out of these products after repeated use, heating, and/or cleaning of the...

journal_title：BioMed research international

authors： Rowdhwal SSS,Chen J

更新日期：2018-02-22 00:00:00

abstract：:This work evaluated the physicochemical properties and antioxidant activity of spray dried extracts (SDE) from Psidium guajava L. leaves. Different drying carriers, namely, maltodextrin, colloidal silicon dioxide, Arabic gum, and β -cyclodextrin at concentrations of 40 and 80% relative to solids content, were added to...

journal_title：BioMed research international

authors： Fernandes MR,Azzolini AE,Martinez ML,Souza CR,Lucisano-Valim YM,Oliveira WP

更新日期：2014-01-01 00:00:00