Role of thiol agents in protecting against the toxicity of helenalin in tumor-bearing mice.

abstract：:A callus culture of Aleurites fordii Hemsley (Euphorbiaceae) producing five galloylglucoses and an ellagitannin, geraniin, was established. The production of pentagalloylglucose was remarkably enhanced under light irradiation compared with that in the dark. Cell growth and tannin production were also greatly affected ...

journal_title：Planta medica

authors： Taniguchi S,Uechi K,Kato R,Ito H,Hatano T,Yazaki K,Yoshida T

更新日期：2002-12-01 00:00:00

abstract：:Baicalein, berberine, curcumin and hesperidin are the major components derived from Scutellaria baicalensis, Coptis japonica, Curcuma longa and Poncirus trifoliata, respectively. These plants have been used for the treatment of diverse chronic inflammatory diseases including respiratory disease in oriental medicine an...

journal_title：Planta medica

authors： Lee CJ,Lee JH,Seok JH,Hur GM,Park YC,Seol IC,Kim YH

更新日期：2003-06-01 00:00:00

abstract：:Thalivarmine and thalsivasine, together with the known bases thalmelatidine, thalicberine, O-methylthalicberine, thaliphylline, thalmethine, O-methylthalmethine and (-)- N-methylcanadine have been isolated from the above ground parts of THALICTRUM MINUS var. MINUS L. ...

journal_title：Planta medica

authors： Başer KH,Kinmer N

更新日期：1985-10-01 00:00:00

abstract：:Four new benzofurans trans-5-(3-hydroxypropyl)-7-methoxy-2-[2,3-dihydro-3-hydroxymethyl-7-methoxy-2-(3-methoxy-4-hydroxyphenyl)-benzofuran-5-yl]benzofuran (1), (E)-5-(2-formylvinyl)-7-methoxy-2-(3,4-methylenedioxyphenyl)benzofuran (2), 5-(3-butanoyloxypropyl)-7-methoxy-2-(3,4-methylenedioxyphenyl)benzofuran (3), and 5...

journal_title：Planta medica

authors： Li QL,Li BG,Qi HY,Gao XP,Zhang GL

更新日期：2005-09-01 00:00:00

abstract：:Cnidicin (1) and five related coumarins were isolated from the root extract of Angelica koreana (Umbelliferae) as active principles responsible for the inhibitory effect on the degranulation process of cultured mast cells. Cnidicin (1) demonstrated a significant inhibition upon the release of beta-hexosaminidase from ...

journal_title：Planta medica

authors： Ryu SY,Kou NY,Choi HS,Ryu H,Kim TS,Kim KM

更新日期：2001-03-01 00:00:00

abstract：:A reinvestigation of the rhizomes of ATRACTYLIS KOREANA afforded in addition to 1,3-diacetoxytetradeca-6,12-diene-8,10-diyne reported previously (1) two new C (14)-polyacetylenes with an ene-diyn-ene-chromophor and one new C (14)-polyacetylene beside two known compounds with an ene-diyne-diene-chromophor. Their struct...

journal_title：Planta medica

authors： Pachaly P,Lansing A,Neugebauer M,Sin KS

更新日期：1990-10-01 00:00:00

abstract：:Ischemic preconditioning, which is mediated by cell signaling molecules, protects the heart from ischemia-reperfusion injury by limiting the infarct size. Oleuropein, the main polyphenolic constituent of olives, reduced the infarct size in normal and cholesterol-fed rabbits when it was administered at a nutritional do...

journal_title：Planta medica

authors： Andreadou I,Benaki D,Efentakis P,Bibli SI,Milioni AI,Papachristodoulou A,Zoga A,Skaltsounis AL,Mikros E,Iliodromitis EK

更新日期：2015-06-01 00:00:00

abstract：:In the present study, we attempted to compare quercetin methyl ethers and to look for the structure-activity relationships, which may be helpful for synthesizing more active compounds for the treatment of asthma. Four present and two previously studied quercetin methyl ethers concentration-dependently relaxed histamin...

journal_title：Planta medica

authors： Ko WC,Kuo SW,Sheu JR,Lin CH,Tzeng SH,Chen CM

更新日期：1999-04-01 00:00:00

abstract：:A micellar electrokinetic capillary chromatography (MEKC) method for the determination of xanthyletin and xanthoxyletin in the roots bark of three Citrus plants was developed for the first time. The electrophoresis buffer was 10 mmol/L sodium borate containing 50 mmol/L sodium dodecyl sulfate, 20% (v/v) acetonitrile a...

journal_title：Planta medica

authors： Wang SF,Ju Y,Chen XG,Hu ZD

更新日期：2003-05-01 00:00:00

abstract：:Sungucine and isosungucine are two bisindole alkaloids isolated from the roots of the African plant Strychnos icaja Baillon. They both exhibit antiplasmodial activities but also show cytotoxic effects against human cancer cell lines. In order to elucidate their mechanism of action, we have investigated the interaction...

journal_title：Planta medica

authors： Lansiaux A,Bailly C,Houssier C,Colson P,De Pauw-Gillet MC,Frédérich M,Tits M,Angenot L

更新日期：2002-07-01 00:00:00

abstract：:Olive mill waste water is the major byproduct of the olive oil industry containing a range of compounds related to Olea europaea and olive oil constituents. Olive mill waste water comprises an important environmental problem in olive oil producing countries, but it is also a valuable material for the isolation of high...

journal_title：Planta medica

authors： Vougogiannopoulou K,Angelopoulou MT,Pratsinis H,Grougnet R,Halabalaki M,Kletsas D,Deguin B,Skaltsounis LA

更新日期：2015-08-01 00:00:00

abstract：:Eleven sesquiterpenoids have been isolated from the whole plants of Youngia japonica (Asteraceae). Among these sesquiterpenoids, five were identified as new compounds on the basis of spectroscopic methods and chemical analysis. Their structures were 3-oxo-8alpha-(4-hydoxyphenyl)acetoxy-10(14),11(13)-guaiadien-12,6-oli...

journal_title：Planta medica

authors： Chen W,Liu Q,Wang J,Zou J,Meng D,Zuo J,Zhu X,Zhao W

更新日期：2006-02-01 00:00:00

abstract：:The inhibition of aflatoxin B1 (AFB1) metabolism by a water extract of the root of Scutellaria baicalensis and its flavonoids was examined in liver microsomes. AFB1 is known to be metabolized to aflatoxin M1 (AFM1), aflatoxin Q1 (AFQ1), and AFB1-8,9-epoxide (AFBO). The water extract potently inhibited the production o...

journal_title：Planta medica

authors： Kim BR,Kim DH,Park R,Kwon KB,Ryu DG,Kim YC,Kim NY,Jeong S,Kang BK,Kim KS

更新日期：2001-07-01 00:00:00

abstract：:In the course of our screening program for acyl-CoA : cholesterol acyltransferase (ACAT) inhibitors from Korean herbal medicines, ACAT inhibitors were isolated from the hairy roots of Panax ginseng (Araliaceae) and identified as panaxynol, panaxydol, panaxydiol, and panaxytriol. These active compounds inhibit rat live...

journal_title：Planta medica

authors： Kwon BM,Ro SH,Kim MK,Nam JY,Jung HJ,Lee IR,Kim YK,Bok SH

更新日期：1997-12-01 00:00:00

abstract：:Geniposide, a main iridoid glucoside component of gardenia fruit, has been shown to possess anti-inflammatory activity. However, its potential use for acute lung injury (ALI) has not yet been studied. The aim of this study was to evaluate the anti-inflammatory properties of geniposide using a mouse ALI model. ALI was ...

journal_title：Planta medica

authors： Xiaofeng Y,Qinren C,Jingping H,Xiao C,Miaomiao W,Xiangru F,Xianxing X,Meixia H,Jing L,Jingyuan W,Xinxin C,Hongyu L,Yanhong D,Lanxiang J,Xuming D

更新日期：2012-04-01 00:00:00

abstract：:In natural product research, the isolation of biomarkers or bioactive compounds from complex natural extracts represents an essential step for de novo identification and bioactivity assessment. When pure natural products have to be obtained in milligram quantities, the chromatographic steps are generally labourious an...

journal_title：Planta medica

authors： Challal S,Queiroz EF,Debrus B,Kloeti W,Guillarme D,Gupta MP,Wolfender JL

更新日期：2015-11-01 00:00:00

abstract：:Infusions of Citrullus colocynthis Schrad. (Cucurbitaceae) fruits are traditionally used as antidiabetic medication in Mediterranean countries, but to our knowledge no studies have been undertaken so far to determine the possible mechanisms involved in the antidiabetic properties of the fruit. The present study was de...

journal_title：Planta medica

authors： Nmila R,Gross R,Rchid H,Roye M,Manteghetti M,Petit P,Tijane M,Ribes G,Sauvaire Y

更新日期：2000-06-01 00:00:00

abstract：:Targeted isolation based on a combination of NMR and HPLC-PDA-MS of a dichloromethane extract of Thymus vulgaris Varico 3 aerial parts afforded one new p-cymene dimer, 6,3',4'-trihydroxy-5,5'-diisopropyl-2,2'-dimethylbiphenyl (1: ), together with two known p-cymene derivatives (2: and 3: ), as well as five known compo...

journal_title：Planta medica

authors： Stefanis I,Hadjipavlou-Litina D,Bilia AR,Karioti A

更新日期：2019-08-01 00:00:00

abstract：:We have examined the immunosuppressive effects of representative ginsenosides (Rb1, Rb2, Re and Rg1) from Panax ginseng C. A. Meyer on CD4+ and CD8+ lymphocyte proliferation. Ginsenosides differentially modulated lymphocyte proliferation induced by concanavalin A (Con A), lipopolysaccharide (LPS), phytohemaglutinin (P...

journal_title：Planta medica

authors： Cho JY,Kim AR,Yoo ES,Baik KU,Park MH

更新日期：2002-06-01 00:00:00

abstract：:Two new C-benzylated dihydrochalcone derivatives, 4,2',4'-trihydroxy-6'-methoxy-3'(2''-hydroxybenzyl)dihydrochalcone (1) and 2',4'-dihydroxy-4,6'-dimethoxy-3'(2''-hydroxybenzyl)dihydrochalcone (2), along with six known flavonoid derivatives (3-8), a known dihydrochalcone dimer (9), three known aromatic esters (10-12),...

journal_title：Planta medica

authors： Prawat U,Chairerk O,Phupornprasert U,Salae AW,Tuntiwachwuttikul P

更新日期：2013-01-01 00:00:00

abstract：:Purification of a cytotoxic crude alkaloid extract of Cassytha filiformis led to the isolation of four known aporphine alkaloids: neolitsine, dicentrine, cassythine (= cassyfiline) and actinodaphnine. Their structures were determined by analysis of spectroscopic data. All isolated alkaloids were tested for their cytot...

journal_title：Planta medica

authors： Stévigny C,Block S,De Pauw-Gillet MC,de Hoffmann E,Llabrès G,Adjakidjé V,Quetin-Leclercq J

更新日期：2002-11-01 00:00:00

abstract：:A museum collection of Cinchonae cortex samples (n = 117), from the period 1850-1950, was extracted with a mixture of chloroform-d1, methanol-d4, water-d2, and perchloric acid in the ratios 5 : 5 : 1 : 1. The extracts were directly analyzed using 1H NMR spectroscopy (600 MHz) and the spectra evaluated using principal ...

journal_title：Planta medica

authors： Yilmaz A,Nyberg NT,Jaroszewski JW

更新日期：2012-11-01 00:00:00

abstract：:The methanolic extract of the fruits of Torilis japonica showed a potent inhibition against 5 alpha-reductase activity in vitro. Bioassay-guided fractionation of the methanol extract of the fruits followed by repeated silica gel chromatography led to the isolation of an active principle and its structure was identifie...

journal_title：Planta medica

authors： Park WS,Son ED,Nam GW,Kim SH,Noh MS,Lee BG,Jang IS,Kim SE,Lee JJ,Lee CH

更新日期：2003-05-01 00:00:00

abstract：:Extract of Tan-Shen (Salvia miltiorrhiza, Labiatae), a Chinese traditional crude drug, was reported to show beneficial activity for heart disease. Chemical examination on the extract was performed on the basis of screening for protective action on the ischemic myocardium. Isolated hearts were subjected to hypoxic perf...

journal_title：Planta medica

authors： Yagi A,Fujimoto K,Tanonaka K,Hirai K,Takeo S

更新日期：1989-02-01 00:00:00

abstract：:PAPAVER SOMNIFERUM L. tissue cultures, issued from various explants (cotyledons, hypocotyls, roots) derived from plantlets belonging to two genotypes, were established on LS solid medium containing growth regulators (NAA, Kin) in various combinations. Hypocotyls and roots were found to be interesting explants to obtai...

journal_title：Planta medica

authors： Laurain-Mattar D,Gillet-Manceau F,Buchon L,Nabha S,Fliniaux MA,Jacquin-Bubreuil A

更新日期：1999-03-01 00:00:00

abstract：:A cytotoxic compound was purified from the root of Angelica gigas Nakai by normal phase HPLC. As a result of the structure analysis by mass, IR, 1H-NMR, and 13C-NMR spectrometry, the compound was identified as decursinol angelate, a structural isomer of decursin, and characterized originally from Sesei grandivittatum....

journal_title：Planta medica

authors： Ahn KS,Sim WS,Lee IK,Seu YB,Kim IH

更新日期：1997-08-01 00:00:00

abstract：:Flavonoids are metabolized in vivo to monocyclic phenolic acids. We investigated whether 18 phenolic acids of the benzoic, phenylacetic, phenylpropanoic or cinnamic series-known or potential metabolites of flavonoids-inhibit reactive oxygen species (ROS) released by human polymorphonuclear neutrophils (PMNs). Chemilum...

journal_title：Planta medica

authors： Limasset B,Ojasoo T,le Doucen C,Doré JC

更新日期：1999-02-01 00:00:00

abstract：:Three new tetrahydroprotoberberine N-oxide alkaloids, (-)- cis-corydalmine N-oxide, (-)- trans-corydalmine N-oxide, and (-)- trans-isocorypalmine N-oxide, along with three known benzo[ C]phenanthridine alkaloids, norsanguinarine, dihydrosanguinarine, and oxysanguinarine, six known berberine alkaloids, (-)-tetrahydropa...

journal_title：Planta medica

authors： Chen JJ,Duh CY,Chen IS

更新日期：1999-10-01 00:00:00

abstract：:The mechanism of action, leakage of cytochrome c from mitochondria into cytosol, for the antineoplastic compound glyfoline was examined. Additionally, our current studies revealed that glyfoline induced apoptotic changes and arrested cell cycle procession at the G2/M phase in nasopharyngeal carcinoma (NPC). A reverse ...

journal_title：Planta medica

authors： Su TL,Huang HM,Wang CK,Wu HC,Lin CT

更新日期：2005-01-01 00:00:00

abstract：:From the defatted seeds of Cassia marginata fam (Caesalpinaceae) two new anthraquinone glycosides have been isolated and characterised as physcion-8-O-alpha-L-xylopyranoside and emodin-8-O-alpha-L-arabinopyranoside. ...

journal_title：Planta medica

authors： Duggal JK,Misra K

更新日期：1982-05-01 00:00:00