Somatic embryogenesis and rhizogenesis of tissue cultures of two genotypes of Papaver somniferum: relationships to alkaloids production.

abstract：:Three new lycopodium alkaloids, 11alpha-hydroxyphlegmariurine B (2), 7alpha-hydroxyphlegmariurine B (3) and 7alpha,11alpha-dihydroxyphlegmariurine B (4) along with a known compound, phlegmariurine B (1), were isolated from the herb Huperzia serrata. The structures of the above compounds were elucidated based on spectr...

journal_title：Planta medica

authors： Tan CH,Wang BD,Jiang SH,Zhu DY

更新日期：2002-02-01 00:00:00

abstract：:The inhibitory activity of stilbenes isolated from medicinal plants on cell adhesion molecules on the surface of THP-1 human monocytic cell lines was investigated. Among ten stilbenes tested, four stilbenes displayed a significant inhibitory activity on the expression of both intercellular adhesion molecule-1 (ICAM-1)...

journal_title：Planta medica

authors： Ahn KS,Kim JH,Oh SR,Ryu SY,Lee HK

更新日期：2000-10-01 00:00:00

abstract：:Six new triterpenoid saponins, psychotrianosides A-F (1-6), and two known triterpenoid saponins, psychotrianoside G (7) and ardisianoside D (8), were isolated from Psychotria sp. Their structures were determined mainly by spectroscopic methods. The cytotoxic activities of 1-8 against five human cancer cell lines (MDA-...

journal_title：Planta medica

authors： Zhang CX,Zhang DM,Chen MF,Guan SY,Yao JH,He XX,Lei LF,Zhong Y,Wang ZF,Ye WC

更新日期：2013-07-01 00:00:00

abstract：:Astilbin, a flavonoid compound, was isolated from the rhizome of Smilax glabra Roxb. This study was conducted to investigate the efficacy of astilbin on experimental diabetic nephropathy (DN) in vivo and in vitro and its possible mechanisms. Astilbin was added in high glucose stimulated HK-2 cells, streptozotocin-indu...

journal_title：Planta medica

authors： Li GS,Jiang WL,Yue XD,Qu GW,Tian JW,Wu J,Fu FH

更新日期：2009-11-01 00:00:00

abstract：:Andrographolide (Andro) is a potentially anti-inflammatory diterpenoid lactone isolated from the traditional herbal medicine ANDROGRAPHIS PANICULATA, which has been effectively used for the treatment of infection, inflammation, cold, fever and diarrhea in China for centuries. In the current study, we found that Andro ...

journal_title：Planta medica

authors： Ji L,Liu T,Liu J,Chen Y,Wang Z

更新日期：2007-10-01 00:00:00

abstract：:The natural compound tyropeptin A, a new peptidyl aldehyde proteasome inhibitor, was tested for its trypanocidal activity in vitro using culture-adapted bloodstream forms of Trypanosoma brucei. The concentrations of tyropeptin A required to reduce the growth rate by 50 % and to kill all cells were 10 and 100 times low...

journal_title：Planta medica

authors： Steverding D,Pemberton AJ,Royle H,Spackman RW,Rivett AJ

更新日期：2006-06-01 00:00:00

abstract：:Chemical investigation of the EtOH extract of Morus alba L. (Moraceae), as guided by free radical scavenging activity, furnished 5,7-dihydroxycoumarin 7-methyl ether (1), two prenylflavones, cudraflavone B (2) and cudraflavone C (3), and oxyresveratrol (4). Compounds 1 and 4 showed superoxide scavenging effects with t...

journal_title：Planta medica

authors： Oh H,Ko EK,Jun JY,Oh MH,Park SU,Kang KH,Lee HS,Kim YC

更新日期：2002-10-01 00:00:00

abstract：:Compelling evidence suggests that infiltrating CD4+ type I helper T (Th1) cells in the pancreatic islets play a pivotal role in the progression of diabetes in non-obese diabetic (NOD) mice. We demonstrate in the present report that a butanol fraction of B. pilosa suppressed the development of diabetes, helped maintain...

journal_title：Planta medica

authors： Chang SL,Chang CL,Chiang YM,Hsieh RH,Tzeng CR,Wu TK,Sytwu HK,Shyur LF,Yang WC

更新日期：2004-11-01 00:00:00

abstract：:For quantitative determination of grayanotoxin I (1) in plant material, a GC/MS method was developed after trimethylsilyl derivatisation of the analytes. Forskolin (5) was used as an internal standard for quantification. ICH-compliant method validation indicated sufficient specificity, precision, quantitation (15 µg/m...

journal_title：Planta medica

authors： Lechtenberg M,Dierks F,Sendker J,Louis A,Schepker H,Hensel A

更新日期：2014-10-01 00:00:00

abstract：:The medicinal properties of curcumin obtained from Curcuma longa L. cannot be utilised because of poor bioavailability due to its rapid metabolism in the liver and intestinal wall. In this study, the effect of combining piperine, a known inhibitor of hepatic and intestinal glucuronidation, was evaluated on the bioavai...

journal_title：Planta medica

authors： Shoba G,Joy D,Joseph T,Majeed M,Rajendran R,Srinivas PS

更新日期：1998-05-01 00:00:00

abstract：:In natural product chemistry, it is often crucial to determine sugar composition as well as the absolute configuration of each monosaccharide in glycosides. An ultra-performance liquid chromatography method using both photodiode array (PDA) and mass spectrometry detectors (UPLC-UV/MS) was developed for qualitative ana...

journal_title：Planta medica

authors： Wang YH,Avula B,Fu X,Wang M,Khan IA

更新日期：2012-05-01 00:00:00

abstract：:EGFR, as a critical signaling pathway in many human tumors, has become an important target of cancer drug design. Taspine has shown meaningful angiogenesis activity in previous studies. This paper is to investigate the antitumor action of taspine by modulating the EGFR signaling pathway. The study determined the expre...

journal_title：Planta medica

authors： Zhang Y,Zheng L,Zhang J,Dai B,Wang N,Chen Y,He L

更新日期：2011-11-01 00:00:00

abstract：:Two triterpenoidal saponins having phytolaccagenin as the aglycone were isolated from the roots of Phytolacca esculenta (Phytolaccaceae). The structures of two new saponins, esculentoside I and esculentoside N, were established to be 3-O-[beta-D-glucopyranosyl-(1----4)-beta-D- glucopyranosyl]-28-O-beta-D-glucopyranosy...

journal_title：Planta medica

authors： Yi YH

更新日期：1992-02-01 00:00:00

abstract：:The new diterpenoids, candesalvoquinone, 12- O-methylcandesalvone B, candesalvone B methyl ester with the 3,4-secoabietane skeleton, and candelabroquinone with the abietane skeleton were isolated from the aerial parts of Salvia candelabrum, together with the known compound candelabrone. The structures were established...

journal_title：Planta medica

authors： Hohmann J,Janicsák G,Forgo P,Rédei D,Máthé I,Bartók T

更新日期：2003-03-01 00:00:00

abstract：:Four p-terphenyl derivatives named curtisians I-L (1-4) were isolated from the MeOH extract of the fruit bodies of Paxillus curtisii. Their structures were elucidated by 2D NMR, MS, IR and UV spectroscopy and chemical reaction. The absolute configurations of curtisians were determined by GC-MS on a chiral column of th...

journal_title：Planta medica

authors： Quang DN,Hashimoto T,Nukada M,Yamamoto I,Tanaka M,Asakawa Y

更新日期：2003-11-01 00:00:00

abstract：:Extracellular polysaccharides (ECP) were isolated in yields of up to 4 mg/ml from the culture media of suspension-cultured cells from Digitalis lanata Ehrh. ECP content was increasing continuously over the first ten days of cultivation and then stayed constant until day 20. ECP were fractionated by ion-exchange chroma...

journal_title：Planta medica

authors： Hensel A,Schmidgall J,Kreis W

更新日期：1997-10-01 00:00:00

abstract：:Two new 8-oxotetrahydroprotoberberine alkaloids, gusanlung A(1) and B(2), together with known isoquinoline alkaloids, berberine and jatrorrhizine, were isolated from the Chinese medicinal plant Acangelisia gusanlung H. S. Lo (Menispermaceae). Their structures were elucidated mainly by spectroscopic analysis. ...

journal_title：Planta medica

authors： Zhang JS,Chen ZL

更新日期：1991-10-01 00:00:00

abstract：:Despite the huge diversity of antibacterial compounds, bacterial resistance to first-choice antibiotics has been drastically increasing. Moreover, the association between multiresistant microorganisms and nosocomial infections highlight the problem, and the urgent need for solutions. Natural resources have been exploi...

journal_title：Planta medica

authors： Alves MJ,Ferreira IC,Dias J,Teixeira V,Martins A,Pintado M

更新日期：2012-11-01 00:00:00

abstract：:Volatile constituents of the essential oils from leaves and inflorescences of Solidago chilensis Meyen were analyzed by GC-FID, GC-MS and 13C-NMR and thirty-six different compounds were identified. Pumiloxide, an unusual labdane diterpene, was found to be one of the major components in both oils (15.3 % and 12.3 %, re...

journal_title：Planta medica

authors： Vila R,Mundina M,Tomi F,Furlán R,Zacchino S,Casanova J,Cañigueral S

更新日期：2002-02-01 00:00:00

abstract：:The inhibition of butyrylcholinesterase activity in human serum by protoberberine, benzophenanthridine and aporphine alkaloids as well as four model compounds has been studied. The mechanism of the inhibition is discussed on the basis of the different types of interaction of these compounds with butyrylcholinesterase ...

journal_title：Planta medica

authors： Ulrichová J,Walterová D,Preininger V,Simánek V

更新日期：1983-07-01 00:00:00

abstract：:In the present study, we demonstrate that saucernetin-8 ( 1) and saucernetin-7 ( 2), isolated from the underground parts of Saururus chinensis (Saururaceae), exerted potent inhibitory effects on LPS-induced nitric oxide (NO) and prostaglandin E (2) (PGE (2)) production in RAW 264.7 cells. Both compounds 1 and 2, known...

journal_title：Planta medica

authors： Park HJ,Kim RG,Seo BR,Ha J,Ahn BT,Bok SH,Lee YS,Kim HJ,Lee KT

更新日期：2003-10-01 00:00:00

abstract：:Some enzymes of the terminal steps of phenylalanine and tyrosine biosyntheses were investigated in various alkaloid-forming ergot strains. All strains studied utilize both arogenate and phenylpyruvate as an intermediate in L-phenylalanine synthesis. L-Tyrosine is preferentially or exclusively synthesized via the aroge...

journal_title：Planta medica

authors： Schmauder HP,Gröger D

更新日期：1986-10-01 00:00:00

abstract：:The present study is aimed at evaluating the effects of luteolin on the scratching behavior associated with an allergic cutaneous reaction in mice. Elicitation of passive cutaneous anaphylaxis, and intradermal injections of compound 48/80, histamine or serotonin induced scratching behavior in ICR mice. Models of irrit...

journal_title：Planta medica

authors： Baolin L,Weiwei W,Ning T

更新日期：2005-05-01 00:00:00

abstract：:The quantification of free and total alkannins in 13 endemic Anatolian Alkanna species is described for the first time. Extraction of the samples was performed by sonication with hexane, followed by hydrolysis in 1 N NaOH. For analysis, a new HPLC method, utilizing reversed phase material (Synergi Max RP), was develop...

journal_title：Planta medica

authors： Pekin G,Ganzera M,Senol S,Bedir E,Korkmaz KS,Stuppner H

更新日期：2007-03-01 00:00:00

abstract：:In this study the first supercritical fluid based protocol for the extraction, analysis, and isolation of six polar compounds, i.e., o-vanillin (1), styracin (2), vanillin (3), trans-cinnamic acid (4), vanillic acid (5), and shikimic acid (6), was developed. First, eight styrax resin products (R1-R8) obtained from var...

journal_title：Planta medica

authors： Scheuba J,Wronski VK,Rollinger JM,Grienke U

更新日期：2017-08-01 00:00:00

abstract：:Two new lactones, 1 and 2, together with five known compounds, 3-7, were isolated from the marine mangrove fungus Xylaria sp. BL321. Their structures were determined by comprehensive analysis of their MS and NMR spectroscopic data. The absolute configurations of 1 and 2 were established on the basis of electronic circ...

journal_title：Planta medica

authors： Song YX,Wang J,Li SW,Cheng B,Li L,Chen B,Liu L,Lin YC,Gu YC

更新日期：2012-01-01 00:00:00

abstract：:The essential oil obtained from the aerial parts of Phlomis lanata has been analyzed by GC/MS. 48 compounds representing 96.85% of the oil were identified; alpha-pinene, limonene and trans-caryophyllene were found as its main components. The essential all showed a moderate in vitro activity against six Gram (+/-) bact...

journal_title：Planta medica

authors： Couladis M,Tanimanidis A,Tzakou O,Chinou IB,Harvala C

更新日期：2000-10-01 00:00:00

abstract：:Reinvestigating the constituents of the roots of Vitis thunbergii Sieb. & Zucc. led to the isolation of three new resveratrol derivatives, vitisinols E-G (1-3), together with 14 known compounds. The structures of compounds 1-3 were established by application of spectroscopic analyses (NMR, MS, UV, and IR). ...

journal_title：Planta medica

authors： Chiou WF,Shen CC,Chen CC,Lin CH,Huang YL

更新日期：2009-06-01 00:00:00

abstract：:Bioactivity-guided fractionation of Saururus chinensis (Saururaceae) using a lymphoproliferation assay led us to isolate 5 lignans (compounds 1 - 5). Compounds 1 - 5 were identified as sauchinone, (-)-saucerneol, saucerneol C, manassantin A, and manassantin B, respectively, by spectroscopic analyses. The immunosuppres...

journal_title：Planta medica

authors： Park SY,Lee SH,Choi WH,Koh EM,Seo JH,Ryu SY,Kim YS,Kwon DY,Koh WS

更新日期：2007-06-01 00:00:00

abstract：:Three new sauchinone analogues, sauchinones B-D (1-3), together with sauchinone (4), were isolated from the aerial part of Saururus chinensis. Structures of the new compounds were determined by extensive spectroscopic data as well as X-ray analysis. Compounds 3 and 4 inhibited nitric oxide production in lipopolysaccha...

journal_title：Planta medica

authors： Gao X,He J,Wu XD,Peng LY,Dong LB,Deng X,Li Y,Cheng X,Zhao QS

更新日期：2013-12-01 00:00:00