Avocado Oil Improves Mitochondrial Function and Decreases Oxidative Stress in Brain of Diabetic Rats.

abstract：Background:The risk factors for acute kidney injury (AKI) development in patients with diabetes hospitalized for COVID-19 have not been fully studied yet. In this study, we aimed to estimate the rate of AKI among the hospitalized population with COVID-19 and to identify the risk factors associated with AKI among patien...

journal_title：Journal of diabetes research

authors： Khalili S,Sabaghian T,Sedaghat M,Soroureddin Z,Askari E,Khalili N

更新日期：2021-01-06 00:00:00

abstract：:Oxidative stress is enhanced by various mechanisms. Serum oxidized low-density lipoprotein (LDL) is a useful prognostic marker in diabetic patients with coronary artery disease. To examine the effects of Theracurmin®, a highly absorbable curcumin preparation, on glucose tolerance, adipocytokines, and oxidized LDL, we ...

journal_title：Journal of diabetes research

authors： Funamoto M,Shimizu K,Sunagawa Y,Katanasaka Y,Miyazaki Y,Kakeya H,Yamakage H,Satoh-Asahara N,Wada H,Hasegawa K,Morimoto T

更新日期：2019-11-23 00:00:00

abstract：:Diabetic retinopathy is the leading cause of blindness in working age individuals in developed countries. However, the role of inflammation in the pathogenesis of DR is not completely understood. This is an observational clinical research enrolling 80 type II diabetic patients who had undergone cataract surgeries eith...

journal_title：Journal of diabetes research

authors： Feng S,Yu H,Yu Y,Geng Y,Li D,Yang C,Lv Q,Lu L,Liu T,Li G,Yuan L

更新日期：2018-04-04 00:00:00

abstract：AIM:The aim of this study was to evaluate the incidence of diabetic ketoacidosis in children and adolescents with newly diagnosed type 1 diabetes in 2006-2007 and 2013-2014. METHOD:The study group consisted of 426 children aged 0-18 years with type 1 diabetes onset admitted to our hospital in 2006-2007 (group A) and 2...

journal_title：Journal of diabetes research

authors： Szypowska A,Ramotowska A,Grzechnik-Gryziak M,Szypowski W,Pasierb A,Piechowiak K

更新日期：2016-01-01 00:00:00

abstract：:Background. The feasibility of digital health programs to prevent and manage diabetes in low-income patients has not been adequately explored. Methods. Researchers collaborated with a digital health company to adapt a diabetes prevention program for low-income prediabetes patients at a large safety net clinic. We cond...

journal_title：Journal of diabetes research

authors： Fontil V,McDermott K,Tieu L,Rios C,Gibson E,Sweet CC,Payne M,Lyles CR

更新日期：2016-01-01 00:00:00

abstract：:Proliferative diabetic retinopathy (PDR) is the leading cause of blindness in working age Americans. We demonstrated that diabetes disturbs the homeostasis of nerve growth factor (NGF) resulting in accumulation of its precursor proNGF. Increases in proNGF were positively correlated with progression of diabetic retinop...

journal_title：Journal of diabetes research

authors： Elshaer SL,Abdelsaid MA,Al-Azayzih A,Kumar P,Matragoon S,Nussbaum JJ,El-Remessy AB

更新日期：2013-01-01 00:00:00

abstract：:Angiotensin-(1-7) [Ang-(1-7)] may have beneficial effects in diabetes mellitus-induced erectile dysfunction (DMIED) but its molecular actions in the diabetic corpus cavernosum (CC) are not known. We characterized the effects of diabetes and/or chronic in vivo administration of Ang-(1-7) on vascular reactivity in the r...

journal_title：Journal of diabetes research

authors： Yousif MH,Makki B,El-Hashim AZ,Akhtar S,Benter IF

更新日期：2014-01-01 00:00:00

abstract：:The aim of this study is to evaluate the effects of regular moderate exercise training initiated previously or after induction of diabetes mellitus on renal oxidative stress and inflammation in STZ-induced diabetic female rats. For this purpose, Wistar rats were divided into five groups: sedentary control (SC), traine...

journal_title：Journal of diabetes research

authors： Amaral LSB,Souza CS,Volpini RA,Shimizu MHM,de Bragança AC,Canale D,Seguro AC,Coimbra TM,de Magalhães ACM,Soares TJ

更新日期：2018-03-29 00:00:00

abstract：:Objective. Diabetic nephropathy is a life-threatening complication in patients with long-standing diabetes. Hemodynamic, inflammatory, and metabolic factors are considered as developmental factors for diabetic nephropathy. In this study, we evaluated whether pharmacological interventions with salicylate, compared to p...

journal_title：Journal of diabetes research

authors： Abouzed TK,Munesue S,Harashima A,Masuo Y,Kato Y,Khailo K,Yamamoto H,Yamamoto Y

更新日期：2016-01-01 00:00:00

abstract：Background:Chronic overnutrition leads to cardiac dysfunction and insulin (INS) resistance. Dipeptidyl peptidase-4 (DPP-4) improves glucose metabolism and insulin sensitivity in both human and animal models. In this study, we explored whether DPP-4 inhibitor sitagliptin (SIT) is involved in the protection of cardiac fu...

journal_title：Journal of diabetes research

authors： Qiao S,Mao G,Li H,Ma Z,Hong L,Zhang H,Wang C,An J

更新日期：2018-07-17 00:00:00

abstract：:The complex diagnosis and treatment of diabetes highlight the need for markers to define how to monitor patients correctly during the course of their disease. Different studies demonstrate the existence of patients who cannot be clearly classified. We have previously shown that it is possible to differentiate "atypica...

journal_title：Journal of diabetes research

authors： Fabregat M,Fernandez M,Javiel G,Vitarella G,Mimbacas A

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Intestinal dysfunction in the ob/ob mouse model of diabetes mimics that seen clinically. METHODS:We determined the effects of a 4-week genistein diet (600 mg genistein/kg food) on intestinal function (contractility, morphology, AChR, and motility) in female ob/ob and lean mice. RESULTS:Contractility of the...

journal_title：Journal of diabetes research

authors： Schacht S,Masood F,Catmull S,Dolan R,Altabtabaee R,Grow W,Al-Nakkash L

更新日期：2017-01-01 00:00:00

abstract：:Type 1 diabetes mellitus (T1DM) is a long-term and chronic autoimmune disorder, in which the immune system attacks the pancreatic β-cells. Both adaptive and innate immune systems are involved in T1DM development. Both B-cells and T-cells, including CD4 + and CD8 ...

journal_title：Journal of diabetes research

authors： Sun L,Xi S,He G,Li Z,Gang X,Sun C,Guo W,Wang G

更新日期：2020-07-30 00:00:00

abstract：Objective:To examine whether comorbidity with type 2 diabetes (T2D) affects the clinical and hematological parameters of coronavirus disease 2019 (COVID-19) patients. Methods:We retrospectively investigated the clinical, imaging, and laboratory characteristics of patients with confirmed COVID-19 who were hospitalized ...

journal_title：Journal of diabetes research

authors： Sun Y,Zhao R,Hu Z,Wang W,Wang S,Gao L,Fei J,Jian X,Li Y,Zheng H,Hou X,Chen L

更新日期：2020-12-02 00:00:00

abstract：:Diabetic nephropathy (DN) is one of the most common causes of end-stage renal failure. This study was performed to determine the effect of Dantonic Pill (DP) treatment on β -catenin expression in a rat model of streptozotocin- (STZ-) induced early-stage DN, with irbesartan treatment as a positive control. Including an...

journal_title：Journal of diabetes research

authors： Shuhong Z,Hongjun L,Bo C,Li X,Bingyin S

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Experimental and clinical studies suggest a possible association between vitamin D deficiency and both diabetic retinopathy and maculopathy. METHODS:We have performed a cross-sectional study in adults with types 1 and 2 diabetes mellitus. The relationship between the presence and severity of diabetic retino...

journal_title：Journal of diabetes research

authors： Alam U,Amjad Y,Chan AW,Asghar O,Petropoulos IN,Malik RA

更新日期：2016-01-01 00:00:00

abstract：Objectives:Tetrahydrobiopterin (BH4) pathway that included generation of neopterin (Neop), biopterin (Biop), and nitric oxide (NO) is altered in type 2 diabetes (T2D). The aim of this study was to assess the biomarkers of BH4 pathway in noninfected DFUs and to relate these levels to the variables of diabetes as well as...

journal_title：Journal of diabetes research

authors： Al-Nimer M,Ratha R,Mahwi T

更新日期：2019-11-16 00:00:00

abstract：:Persons with type 2 diabetes mellitus (T2DM) have an elevated risk of atherosclerosis. High-density lipoproteins (HDL) normally protect against cardiovascular disease (CVD), but this may be attenuated by serum amyloid A (SAA). In a case-control study of young females, blood samples were compared between subjects with ...

journal_title：Journal of diabetes research

authors： Griffiths K,Pazderska A,Ahmed M,McGowan A,Maxwell AP,McEneny J,Gibney J,McKay GJ

更新日期：2017-01-01 00:00:00

abstract：:South Asians have high prevalence of diabetes, cardiovascular risk, and physical inactivity. Reasons for physical inactivity have not been explored among Asians living within their endogenous environments. During phase 1 of the study, we assessed the physical activity (PA) of the population using a quantitative, descr...

journal_title：Journal of diabetes research

authors： Medagama A,Galgomuwa M

更新日期：2018-03-06 00:00:00

abstract：:The objective of this study was to assess the effects of exogenously expressed proinsulin on the biological characters of a hematopoietic stem cell line (HSC) and erythroid myeloid lymphoid (EML) cells and explore new strategies for cell therapy for type I diabetes. EML cells were transduced with lentivirus particles ...

journal_title：Journal of diabetes research

authors： Han Y,Liu T,Zou Y,Ji L,Li Y,Li J,Wang J,Chen G,Chen J,Chen L,Ye Z

更新日期：2017-01-01 00:00:00

abstract：Background:Diabetes mellitus is a widely diffused chronic condition which impacts on several aspects of patients' lives. In the current clinical practice, the implementation in the clinical routine of monitoring systems of patients' outcomes has led to an increased generation and use of several measures for the assessm...

journal_title：Journal of diabetes research

authors： Palamenghi L,Carlucci MM,Graffigna G

更新日期：2020-05-20 00:00:00

abstract：Background:Maternal dietary patterns play an important role in the progress of gestational diabetes mellitus (GDM). The aim of the present study was to explore this association. Method:A total of 388 pregnant women (122 case and 266 control) were included. Dietary intake were collected using a food frequency questionn...

journal_title：Journal of diabetes research

authors： Sedaghat F,Akhoondan M,Ehteshami M,Aghamohammadi V,Ghanei N,Mirmiran P,Rashidkhani B

更新日期：2017-01-01 00:00:00

abstract：Aim:To evaluate the effect of an inhibitor of sodium-glucose cotransporter 2 (SGLT-2 inhibitor, dapagliflozin) on glycemic variability in type 2 diabetes mellitus (T2D) under insulin glargine combined with oral hypoglycemic drugs, using a continuous glucose monitoring system (CGMS). Methods:This prospective, self-cont...

journal_title：Journal of diabetes research

authors： Luo M,Kong X,Wang H,Zhai X,Cai T,Ding B,Hu Y,Jing T,Su X,Li H,Ma J

更新日期：2020-11-24 00:00:00

abstract：:Native Hawaiians and other Pacific Islanders (NH/PI; e.g., Samoan and Chuukese) have higher type 2 diabetes prevalence compared to other groups in Hawai'i. Partners in Care (PIC), a culturally tailored, community-based, diabetes self-management education intervention (DSME), is effective at improving participants' gly...

journal_title：Journal of diabetes research

authors： Ing CT,Zhang G,Dillard A,Yoshimura SR,Hughes C,Palakiko DM,Kehauoha BP,Sinclair KA,Kaholokula JK

更新日期：2016-01-01 00:00:00

abstract：Objective:The aim of the study was to investigate the independent and combined effects of the cortisol-to-cortisone ratio (F/E) and 11-deoxycortisol on prediabetes and type 2 diabetes mellitus (T2DM) among different genders. Methods:A case-control study was performed including 2676 participants from the Henan Rural Co...

journal_title：Journal of diabetes research

authors： Liu X,Jiang J,Liu X,Luo Z,Wang Y,Dong X,Wei D,Huo W,Yu S,Li L,Jin S,Wang C,Mao Z

更新日期：2019-06-02 00:00:00

abstract：:Glucokinase (GK) plays a critical role in the control of whole-body glucose homeostasis. We investigated the possible effects of a novel glucokinase activator (GKA), HMS5552, to the GK in rats with type 2 diabetes mellitus (T2DM). Male Sprague-Dawley (SD) rats were divided into four groups: control group, diabetic gro...

journal_title：Journal of diabetes research

authors： Wang P,Liu H,Chen L,Duan Y,Chen Q,Xi S

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Tumor necrosis factor-α-induced protein 8-like 2 (TIPE2 or TNFAIP8L2) is a negative regulator of natural and adaptive immunity. The role of TIPE2 in type 2 diabetes mellitus (T2DM) remains unknown, although TIPE2 plays key roles in preserving inflammatory homeostasis. METHODS:TIPE2 expression was measured b...

journal_title：Journal of diabetes research

authors： Liu Y,Wang X,Zhao Y,Zhao P,Wang L,Zhai Q,Zhang X,Tian W,Xiang X,Li T

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To investigate the association between circulating betatrophin level and type 2 diabetes mellitus (T2DM) in human. METHODS:A comprehensive literature search was performed in PubMed and Embase databases to identify eligible studies assessing the circulating levels of betatrophin in both T2DM patients and nond...

journal_title：Journal of diabetes research

authors： Li S,Liu D,Li L,Li Y,Li Q,An Z,Sun X,Tian H

更新日期：2016-01-01 00:00:00

abstract：:The proliferation of vascular smooth muscle cells (VSMCs) is one of the main features of atherosclerosis induced by high glucose. Mevalonate pathway is an important metabolic pathway that plays a key role in multiple cellular processes. The aim of this study was to define whether the enzyme expression in mevalonate pa...

journal_title：Journal of diabetes research

authors： Chen GP,Zhang XQ,Wu T,Li L,Han J,Du CQ

更新日期：2015-01-01 00:00:00

abstract：:We investigated the association of serum homocysteine levels and vitamin status with type 2 diabetic retinopathy. This study included 65 patients with and 75 patients without diabetic retinopathy. Patients with diabetic retinopathy had significantly higher serum homocysteine levels (P < 0.001), higher prevalence of hy...

journal_title：Journal of diabetes research

authors： Fotiou P,Raptis A,Apergis G,Dimitriadis G,Vergados I,Theodossiadis P

更新日期：2014-01-01 00:00:00