Previous Exercise Training Reduces Markers of Renal Oxidative Stress and Inflammation in Streptozotocin-Induced Diabetic Female Rats.

abstract：:The proliferation of vascular smooth muscle cells (VSMCs) is one of the main features of atherosclerosis induced by high glucose. Mevalonate pathway is an important metabolic pathway that plays a key role in multiple cellular processes. The aim of this study was to define whether the enzyme expression in mevalonate pa...

journal_title：Journal of diabetes research

authors： Chen GP,Zhang XQ,Wu T,Li L,Han J,Du CQ

更新日期：2015-01-01 00:00:00

abstract：:Persons with type 2 diabetes mellitus (T2DM) have an elevated risk of atherosclerosis. High-density lipoproteins (HDL) normally protect against cardiovascular disease (CVD), but this may be attenuated by serum amyloid A (SAA). In a case-control study of young females, blood samples were compared between subjects with ...

journal_title：Journal of diabetes research

authors： Griffiths K,Pazderska A,Ahmed M,McGowan A,Maxwell AP,McEneny J,Gibney J,McKay GJ

更新日期：2017-01-01 00:00:00

abstract：:Diabetic retinopathy (DR) is a severe sight-threatening complication of diabetes mellitus. Retinal laser photocoagulation, antivascular endothelial growth factors, steroid therapy, and pars plana vitrectomy are now used extensively to treat advanced stages of diabetic retinopathy. Currently, diagnostic devices like ul...

journal_title：Journal of diabetes research

authors： Park YG,Roh YJ

更新日期：2016-01-01 00:00:00

abstract：:Background. The aim of this study was to validate the impact of type 2 diabetes (T2D) on the platelet reactivity in patients with acute ST elevation myocardial infarction (STEMI) treated with adenosine diphosphate (ADP) receptor blockers. Methods. A pilot prospective study was performed. Totally 67 patients were enrol...

journal_title：Journal of diabetes research

authors： Samoš M,Fedor M,Kovář F,Galajda P,Bolek T,Stančiaková L,Fedorová J,Staško J,Kubisz P,Mokáň M

更新日期：2016-01-01 00:00:00

abstract：AIMS:This study assesses the impact of using an AP-system at home on fear of hypoglycaemia. In addition, satisfaction and acceptance of the new technology are evaluated. METHODS:In a multicentre, multinational study of 75 patients using the MD-Logic AP during four consecutive nights in home setting 59 of them (aged 10...

journal_title：Journal of diabetes research

authors： Ziegler C,Liberman A,Nimri R,Muller I,Klemenčič S,Bratina N,Bläsig S,Remus K,Phillip M,Battelino T,Kordonouri O,Danne T,Lange K

更新日期：2015-01-01 00:00:00

abstract：Background:Previous studies have examined the role of the KQT-like subfamily Q member1 (KCNQ1) gene polymorphisms on the risk of type 2 diabetes mellitus (T2DM), but the findings are inconclusive. Objective:To examine the association between the KCNQ1 gene polymorphisms and the risk of T2DM using an updated meta-analy...

journal_title：Journal of diabetes research

authors： Yu XX,Liao MQ,Zeng YF,Gao XP,Liu YH,Sun W,Zhu S,Zeng FF,Ye YB

更新日期：2020-07-03 00:00:00

abstract：:To observe the changes of lung injury when diabetic rats were treated with low concentration of ethanol (EtOH) and analyze the related mechanisms, male Sprague-Dawley (SD) rats were divided into control, diabetic (DM), and EtOH+DM groups. Diabetic rat was mimicked by injection of streptozotocin intraperitoneally. Fast...

journal_title：Journal of diabetes research

authors： Hu JF,Zhang GJ,Wang L,Kang PF,Li J,Wang HJ,Gao Q,Chen YQ

更新日期：2014-01-01 00:00:00

abstract：:In bioartificial pancreases (BP), the number of islets needed to restore normoglycaemia in the diabetic patient is critical. However, the confinement of a high quantity of islets in a limited space may impact islet survival, particularly in regard to the low oxygen partial pressure (PO2) in such environments. The aim ...

journal_title：Journal of diabetes research

authors： Rodriguez-Brotons A,Bietiger W,Peronet C,Magisson J,Sookhareea C,Langlois A,Mura C,Jeandidier N,Pinget M,Sigrist S,Maillard E

更新日期：2016-01-01 00:00:00

abstract：:Germinated brown rice (GBR) is rich in bioactive compounds, which confer GBR with many functional properties. Evidence of its hypocholesterolemic effects is emerging, but the exact mechanisms of action and bioactive compounds involved have not been fully documented. Using type 2 diabetic rats, we studied the effects o...

journal_title：Journal of diabetes research

authors： Imam MU,Ismail M,Omar AR,Ithnin H

更新日期：2013-01-01 00:00:00

abstract：Aims:To investigate the effect of peer support education model on the levels of glucose and lipids in patients with type 2 diabetes mellitus in China. Methods:120 type 2 diabetes mellitus patients (T2DM) were assigned to two groups randomly from December 2016 to October 2017. Group 1 was trained on basic diabetic medi...

journal_title：Journal of diabetes research

authors： Zhao X,Yu X,Zhang X

更新日期：2019-11-22 00:00:00

abstract：:Metformin is contraindicated in diabetic patients with declining renal function. This study examined the glycaemic control in diabetic patients with chronic kidney disease when metformin was discontinued. This was a retrospective study. We screened 2032 diabetic patients who attended the Diabetes Clinic at a tertiary ...

journal_title：Journal of diabetes research

authors： Leyco T,Ryanputra D,Peh R,Ponce A,Khoo CM

更新日期：2017-01-01 00:00:00

abstract：:T2DM patients demonstrate reduced GLP-1 receptor (GLP-1R) expression in their gastric glands. Whether induced T2DM and T1DM differently affect the gastric GLP-1R expression is not known. This study assessed extrapancreatic GLP-1R system in glandular stomach of rodents with different types of experimental diabetes. T2D...

journal_title：Journal of diabetes research

authors： Bloch O,Broide E,Ben-Yehudah G,Cantrell D,Shirin H,Rapoport MJ

更新日期：2015-01-01 00:00:00

abstract：Background:Diabetic retinopathy (DR) is a severe complication of diabetes mellitus. DR is considered as a neurovascular disease. Retinal ganglion cell (RGC) loss plays an important role in the vision function disorder of diabetic patients. Histone deacetylase3 (HDAC3) is closely related to injury repair and nerve regen...

journal_title：Journal of diabetes research

authors： Fu Y,Wang Y,Gao X,Li H,Yuan Y

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of onsite screening with a nonmydriatic, digital fundus camera for diabetic retinopathy (DR) at a diabetes outpatient clinic. RESEARCH DESIGN AND METHODS:This cross-sectional study included 502 patients, 112 with type 1 and 390 with type 2 diabetes. Patients attended screenings for mic...

journal_title：Journal of diabetes research

authors： Roser P,Kalscheuer H,Groener JB,Lehnhoff D,Klein R,Auffarth GU,Nawroth PP,Schuett F,Rudofsky G

更新日期：2016-01-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) remain as one of the most global problematic metabolic diseases with rapidly increasing prevalence and incidence. Epidemiological studies noted that T2DM patients have by two-fold increase to develop NAFLD, and vice versa. This complex and in...

journal_title：Journal of diabetes research

authors： Tanase DM,Gosav EM,Costea CF,Ciocoiu M,Lacatusu CM,Maranduca MA,Ouatu A,Floria M

更新日期：2020-07-31 00:00:00

abstract：Background:Type 2 diabetes mellitus (T2DM) has become a chronic disease, serious harm to human health. Complications of the blood pipe are the main cause of disability and death in diabetic patients, including vascular lesions that directly affects the prognosis of patients with diabetes and survival. This study was to...

journal_title：Journal of diabetes research

authors： Gao JR,Qin XJ,Fang ZH,Li-Shan,Han LP,Hui-Jiang,Guo MF,Jiang NN

更新日期：2019-04-17 00:00:00

abstract：:Aims. Dipeptidyl-peptidase IV inhibitors (DPP-4i) are among the most popular oral antidiabetic agents. However, the effects of DPP-4i on diabetic nephropathy are not well-established. The aim of this study was to determine the renoprotective effects of DPP-4i, using albuminuria and glomerular filtration rate (GFR) as ...

journal_title：Journal of diabetes research

authors： Kim YG,Byun J,Yoon D,Jeon JY,Han SJ,Kim DJ,Lee KW,Park RW,Kim HJ

更新日期：2016-01-01 00:00:00

abstract：:The quantitative trait locus (QTL) mapping in segregating crosses of NSY (Nagoya-Shibata-Yasuda) mice, an animal model of type 2 diabetes, with nondiabetic strain C3H/He mice has identified diabetogenic QTLs on multiple chromosomes. The QTL on chromosome 11 (Chr11) (Nidd1n) showing the largest effect on hyperglycemia ...

journal_title：Journal of diabetes research

authors： Babaya N,Ueda H,Noso S,Hiromine Y,Nojima K,Itoi-Babaya M,Kobayashi M,Fujisawa T,Ikegami H

更新日期：2013-01-01 00:00:00

abstract：Objective:The aim of this study was to explore the association of 1,5-anhydroglucitol with acute C peptide response (ACPR) to arginine among patients with type 2 diabetes. Methods:Patients with type 2 diabetes were enrolled from the Department of Endocrinology and Metabolism, Shanghai Sixth People's Hospital. ACPR was...

journal_title：Journal of diabetes research

authors： Shen Y,Si Y,Lu J,Ma X,Zhang L,Mo Y,Lu W,Zhu W,Bao Y,Hu G,Zhou J

更新日期：2020-07-21 00:00:00

abstract：:To evaluate the characteristics and determinants of partial remission (PR) in Belgian children with type 1 diabetes (T1D), we analyzed records of 242 children from our center. Clinical and biological features were collected at diagnosis and during follow-up. PR was defined using the insulin-dose-adjusted A1C definitio...

journal_title：Journal of diabetes research

authors： Pecheur A,Barrea T,Vandooren V,Beauloye V,Robert A,Lysy PA

更新日期：2014-01-01 00:00:00

abstract：:Native Hawaiians and other Pacific Islanders (NH/PI; e.g., Samoan and Chuukese) have higher type 2 diabetes prevalence compared to other groups in Hawai'i. Partners in Care (PIC), a culturally tailored, community-based, diabetes self-management education intervention (DSME), is effective at improving participants' gly...

journal_title：Journal of diabetes research

authors： Ing CT,Zhang G,Dillard A,Yoshimura SR,Hughes C,Palakiko DM,Kehauoha BP,Sinclair KA,Kaholokula JK

更新日期：2016-01-01 00:00:00

abstract：:Diabetes mellitus (DM) is a major worldwide health problem and its prevalence has been rapidly increasing in the last century. It is caused by defects in insulin secretion or insulin action or both, leading to hyperglycemia. Of the various types of DM, type 2 occurs most frequently. Multiple genes and their interactio...

journal_title：Journal of diabetes research

authors： Haghvirdizadeh P,Mohamed Z,Abdullah NA,Haghvirdizadeh P,Haerian MS,Haerian BS

更新日期：2015-01-01 00:00:00

abstract：:Many studies have assessed the association between eNOS-4b/a polymorphism and the risk of diabetic retinopathy (DR) among type 2 diabetic subjects. However, the results are inconsistent. In order to derive a more precise estimation of the association, a meta-analysis was conducted. Fifteen studies with 3, 183 cases an...

journal_title：Journal of diabetes research

authors： Ma ZJ,Chen R,Ren HZ,Guo X,Guo J,Chen LM

更新日期：2014-01-01 00:00:00

abstract：:Children with type 1 diabetes (T1DM) are the high-risk group of accelerated atherosclerosis. Real-time continuous glucose monitoring (RT-CGM) provides possibilities for the detection of glycaemic variability, newly recognized cardiovascular risk factor. The aim of the study was to assess the usefulness of RT-CGM as an...

journal_title：Journal of diabetes research

authors： Jamiołkowska M,Jamiołkowska I,Łuczyński W,Tołwińska J,Bossowski A,Głowińska Olszewska B

更新日期：2016-01-01 00:00:00

abstract：Purpose:We aimed to assess the changes of retinal microvascular parameters using optical coherence tomography angiography (OCTA) between diabetes macular edema (DME) and controls. We assessed the changes between the baseline microvascular parameters and final treatment response in patients with DME, initially treated w...

journal_title：Journal of diabetes research

authors： Park YG,Park YH

更新日期：2020-11-16 00:00:00

abstract：:This study evaluated the inflammatory markers in prediabetes and newly diagnosed type 2 diabetes mellitus (T2DM). Inflammatory markers levels were analyzed using one-way analysis of covariance and the association with prediabetes or T2DM risks was examined by logistic regression models. Our data showed increased level...

journal_title：Journal of diabetes research

authors： Wang Z,Shen XH,Feng WM,Ye GF,Qiu W,Li B

更新日期：2016-01-01 00:00:00

abstract：Purpose:Nontraditional cardiovascular risk factors as apolipoprotein A (ApoA), apolipoprotein B (ApoB), and the proprotein convertase subtilisin/kexin type 9 (PCSK9) increase the prevalence of cardiovascular mortality in chronic kidney disease (CKD) or in end-stage renal disease (ESRD) through quantitative alterations....

journal_title：Journal of diabetes research

authors： Vlad CE,Foia L,Popescu R,Ivanov I,Luca MC,Delianu C,Toma V,Statescu C,Rezus C,Florea L

更新日期：2019-12-14 00:00:00

abstract：:Statin therapy improves lipid profiles and reduces vascular inflammation, but its effects on central arterial stiffness in type 2 diabetes are unclear. The aim of this study was to determine whether statin therapy reduces central arterial stiffness, in a dose-dependent manner, in male patients with type 2 diabetes. Fi...

journal_title：Journal of diabetes research

authors： Davenport C,Ashley DT,O'Sullivan EP,McHenry CM,Agha A,Thompson CJ,O'Gorman DJ,Smith D

更新日期：2015-01-01 00:00:00

abstract：Background:Diabetes mellitus (DM) has become one of the most common chronic metabolic diseases worldwide. Due to the increasing prevalence and various complications, diabetes brings about a huge financial burden to DM patients. Nowadays, more and more studies reveal the relationship between diseases and gut microbial c...

journal_title：Journal of diabetes research

authors： Zhao X,Zhang Y,Guo R,Yu W,Zhang F,Wu F,Shang J

更新日期：2020-11-11 00:00:00

abstract：:Aldehyde dehydrogenase (ALDH) gene superfamily consists of 19 isozymes. They are present in various organs and involved in metabolizing aldehydes that are biologically generated. For instance, ALDH2, a cardiac mitochondrial ALDH isozyme, is known to detoxify 4-hydroxy-2-nonenal, a reactive aldehyde produced upon lipid...

journal_title：Journal of diabetes research

authors： Pan G,Deshpande M,Thandavarayan RA,Palaniyandi SS

更新日期：2016-01-01 00:00:00