Analysis of Inflammatory Mediators in Prediabetes and Newly Diagnosed Type 2 Diabetes Patients.

abstract：:The aim of the current study was to provide updated time-path equations for risk factors of type-2-diabetes-related cardiovascular complications for application in risk calculators and health economic models. Observational data from the Swedish National Diabetes Register were analysed using Generalized Method of Momen...

journal_title：Journal of diabetes research

authors： Ahmad Kiadaliri A,Clarke PM,Gerdtham UG,Nilsson P,Eliasson B,Gudbjörnsdottir S,Steen Carlsson K

更新日期：2013-01-01 00:00:00

abstract：:Type 2 diabetes mellitus is prevalent especially in Gulf countries and poses serious long-term risks to patients. A multifaceted treatment approach can include nutritional supplements with antioxidant properties such as 5-aminolevulinic acid (5-ALA) with sodium ferrous citrate (SFC). This prospective, randomized, sing...

journal_title：Journal of diabetes research

authors： Al-Saber F,Aldosari W,Alselaiti M,Khalfan H,Kaladari A,Khan G,Harb G,Rehani R,Kudo S,Koda A,Tanaka T,Nakajima M,Darwish A

更新日期：2016-01-01 00:00:00

abstract：Background:The risk factors for acute kidney injury (AKI) development in patients with diabetes hospitalized for COVID-19 have not been fully studied yet. In this study, we aimed to estimate the rate of AKI among the hospitalized population with COVID-19 and to identify the risk factors associated with AKI among patien...

journal_title：Journal of diabetes research

authors： Khalili S,Sabaghian T,Sedaghat M,Soroureddin Z,Askari E,Khalili N

更新日期：2021-01-06 00:00:00

abstract：:Gastric emptying and glycemic control pathways are closely interrelated processes. Gastric chyme is transferred into the duodenum with velocities depending on its solid or liquid state, as well as on its caloric and nutritional composition. Once nutrients enter the intestine, the secretion of incretins (hormonal produ...

journal_title：Journal of diabetes research

authors： Mihai BM,Mihai C,Cijevschi-Prelipcean C,Grigorescu ED,Dranga M,Drug V,Sporea I,Lăcătușu CM

更新日期：2018-10-03 00:00:00

abstract：:We present a post hoc analysis of 17,530 questionnaires collected as part of the 2012 screening for neuropathy using Norfolk Quality of Life tool in patients with diabetes in Romania, to assess the impact on foot complications of time between the onset of symptoms of diabetes/its complications and the physician visit....

journal_title：Journal of diabetes research

authors： Gavan NA,Veresiu IA,Vinik EJ,Vinik AI,Florea B,Bondor CI

更新日期：2016-01-01 00:00:00

abstract：:The association between diabetes mellitus (DM) and high mortality linked to cardiovascular disease (CVD) is a major concern worldwide. Clinical and preclinical studies have demonstrated a variety of diastolic and systolic dysfunctions in patients with type 2 diabetes mellitus (T2DM) with the severity of abnormalities ...

journal_title：Journal of diabetes research

authors： Al Kury L,Smail M,Qureshi MA,Sydorenko V,Shmygol A,Oz M,Singh J,Howarth FC

更新日期：2018-04-10 00:00:00

abstract：OBJECTIVE:To compare the serum concentration of IL-6, IL-10, TNF, IL-8, resistin, and adiponectin in type 1 diabetic patients with and without metabolic syndrome and to determine the cut-off point of the estimated glucose disposal rate that accurately differentiated these groups. DESIGN:We conducted a cross-sectional ...

journal_title：Journal of diabetes research

authors： Ferreira-Hermosillo A,Molina-Ayala M,Ramírez-Rentería C,Vargas G,Gonzalez B,Isibasi A,Archundia-Riveros I,Mendoza V

更新日期：2015-01-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) remain as one of the most global problematic metabolic diseases with rapidly increasing prevalence and incidence. Epidemiological studies noted that T2DM patients have by two-fold increase to develop NAFLD, and vice versa. This complex and in...

journal_title：Journal of diabetes research

authors： Tanase DM,Gosav EM,Costea CF,Ciocoiu M,Lacatusu CM,Maranduca MA,Ouatu A,Floria M

更新日期：2020-07-31 00:00:00

abstract：Purpose:We aimed to assess the changes of retinal microvascular parameters using optical coherence tomography angiography (OCTA) between diabetes macular edema (DME) and controls. We assessed the changes between the baseline microvascular parameters and final treatment response in patients with DME, initially treated w...

journal_title：Journal of diabetes research

authors： Park YG,Park YH

更新日期：2020-11-16 00:00:00

abstract：:Angiotensin-(1-7) [Ang-(1-7)] may have beneficial effects in diabetes mellitus-induced erectile dysfunction (DMIED) but its molecular actions in the diabetic corpus cavernosum (CC) are not known. We characterized the effects of diabetes and/or chronic in vivo administration of Ang-(1-7) on vascular reactivity in the r...

journal_title：Journal of diabetes research

authors： Yousif MH,Makki B,El-Hashim AZ,Akhtar S,Benter IF

更新日期：2014-01-01 00:00:00

abstract：Background/Aims:It is known that chronic low-grade inflammation contributes to the initiation and development of both diabetes and diabetic nephropathy (DN), so we designed this study to investigate the role of P2X7R and NLRP3 inflammasome in DN pathogenesis and the antagonistic effects of artificially cultivated Ophio...

journal_title：Journal of diabetes research

authors： Wang C,Hou XX,Rui HL,Li LJ,Zhao J,Yang M,Sun LJ,Dong HR,Cheng H,Chen YP

更新日期：2018-11-11 00:00:00

abstract：Aim:To evaluate the prognostic role of procalcitonin (PCT) in patients with diabetic foot infection (DFI) and critical limb ischemia (CLI). Materials and Methods:The study group was composed of diabetic patients with DFI and CLI. All patients were treated according to a preset limb salvage protocol which includes reva...

journal_title：Journal of diabetes research

authors： Meloni M,Izzo V,Giurato L,Brocco E,Ferrannini M,Gandini R,Uccioli L

更新日期：2019-08-14 00:00:00

abstract：Background:Tracking progression of diabetic peripheral polyneuropathy (DPN) is usually focused on sensory nerves and subjective testing methods. Recent studies have suggested that distal muscle atrophy may precede sensation loss. Methods to objectively measure distal muscle size and strength are needed to help understa...

journal_title：Journal of diabetes research

authors： Henderson AD,Johnson AW,Rasmussen LG,Peine WP,Symons SH,Scoresby KA,Ridge ST,Bruening DA

更新日期：2020-03-12 00:00:00

abstract：:Forefoot load (FL) contributes to callus formation, which is one of the pathways to diabetic foot ulcers (DFU). In this study, we hypothesized that excessive FL, which cannot be detected by plantar load measurements within laboratory settings, occurs in daily walks. To demonstrate this, we created a FL estimation algo...

journal_title：Journal of diabetes research

authors： Watanabe A,Noguchi H,Oe M,Sanada H,Mori T

更新日期：2017-01-01 00:00:00

abstract：:Introduction. Diabetic Ketoacidosis (DKA) is a serious complication that can be life-threatening. Management of DKA needs admission in a specialized center and imposes major constraints on hospital resources. Aim. We plan to study the impact of adapting a diabetes-educator care model on reducing the frequency of hospi...

journal_title：Journal of diabetes research

authors： Deeb A,Yousef H,Abdelrahman L,Tomy M,Suliman S,Attia S,Al Suwaidi H

更新日期：2016-01-01 00:00:00

abstract：Objectives:To investigate the risk factors for cognitive impairment in Chinese type 2 diabetes mellitus (T2DM) patients of advanced age and to identify effective biomarkers of mild cognitive impairment (MCI) in these patients. Methods:Chinese T2DM patients (n = 120) aged 50-70 years were divided into groups with impai...

journal_title：Journal of diabetes research

authors： Sun L,Diao X,Gang X,Lv Y,Zhao X,Yang S,Gao Y,Wang G

更新日期：2020-04-23 00:00:00

abstract：:The complex diagnosis and treatment of diabetes highlight the need for markers to define how to monitor patients correctly during the course of their disease. Different studies demonstrate the existence of patients who cannot be clearly classified. We have previously shown that it is possible to differentiate "atypica...

journal_title：Journal of diabetes research

authors： Fabregat M,Fernandez M,Javiel G,Vitarella G,Mimbacas A

更新日期：2015-01-01 00:00:00

abstract：AIMS:This study assesses the impact of using an AP-system at home on fear of hypoglycaemia. In addition, satisfaction and acceptance of the new technology are evaluated. METHODS:In a multicentre, multinational study of 75 patients using the MD-Logic AP during four consecutive nights in home setting 59 of them (aged 10...

journal_title：Journal of diabetes research

authors： Ziegler C,Liberman A,Nimri R,Muller I,Klemenčič S,Bratina N,Bläsig S,Remus K,Phillip M,Battelino T,Kordonouri O,Danne T,Lange K

更新日期：2015-01-01 00:00:00

abstract：:The rapid rise of type II diabetes mellitus and its accompanying vascular complications call for novel approaches in unravelling its pathophysiological mechanisms and designing new treatment modalities. Noncoding RNAs represent a class of previously unknown molecular modulators of this disease. The most important feat...

journal_title：Journal of diabetes research

authors： Eken SM,Jin H,Chernogubova E,Maegdefessel L

更新日期：2013-01-01 00:00:00

abstract：:Peroxisome proliferator-activated receptor (PPAR) agonists are used for treating hyperglycemia and type 2 diabetes. However, the mechanism of action of these agonists is still under investigation. The lipid droplet-associated proteins FSP27/CIDEC and LSDP5, regulated directly by PPARγ and PPARα, are associated with he...

journal_title：Journal of diabetes research

authors： Zhu YX,Zhang ML,Zhong Y,Wang C,Jia WP

更新日期：2016-01-01 00:00:00

abstract：:Insulin resistance, which plays a central role in the pathogenesis of type 2 diabetes (T2D), is an early indicator that heralds the occurrence of T2D. It is imperative to understand the metabolic changes that occur at the cellular level in the early stages of insulin resistance. The objective of this study was to dete...

journal_title：Journal of diabetes research

authors： Berhane F,Fite A,Daboul N,Al-Janabi W,Msallaty Z,Caruso M,Lewis MK,Yi Z,Diamond MP,Abou-Samra AB,Seyoum B

更新日期：2015-01-01 00:00:00

abstract：Aim:To evaluate the influence of metabolic parameters and the treatment method in children with type 1 diabetes (T1D) on the optical coherence tomography angiography (OCTA) results as early markers of diabetic retinopathy (DR). Material and Methods. This prospective study enrolled 175 consecutive children with T1D. OCT...

journal_title：Journal of diabetes research

authors： Wysocka-Mincewicz M,Baszyńska-Wilk M,Gołębiewska J,Olechowski A,Byczyńska A,Hautz W,Szalecki M

更新日期：2020-11-18 00:00:00

abstract：:Clopidogrel (INN), an oral antiplatelet drug, has been revealed to have a number of biological properties, for instance, anti-inflammation and antioxidation. Oxidative stress plays an imperative role in inflammation, diabetes mellitus, atherosclerosis, and cancer. In the present study, human aortic endothelial cells (...

journal_title：Journal of diabetes research

authors： Yang H,Zhao P,Tian S

更新日期：2016-01-01 00:00:00

abstract：:Inhibition of the potassium channels TREK-1 by spadin (SPA) is currently thought to be a promising therapeutic target for the treatment of depression. Since these channels are expressed in pancreatic β-cells, we investigated their role in the control of insulin secretion and glucose homeostasis. In this study, we conf...

journal_title：Journal of diabetes research

authors： Hivelin C,Béraud-Dufour S,Devader C,Abderrahmani A,Moreno S,Moha Ou Maati H,Djillani A,Heurteaux C,Borsotto M,Mazella J,Coppola T

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To investigate the association between circulating betatrophin level and type 2 diabetes mellitus (T2DM) in human. METHODS:A comprehensive literature search was performed in PubMed and Embase databases to identify eligible studies assessing the circulating levels of betatrophin in both T2DM patients and nond...

journal_title：Journal of diabetes research

authors： Li S,Liu D,Li L,Li Y,Li Q,An Z,Sun X,Tian H

更新日期：2016-01-01 00:00:00

abstract：:Objective. Diabetic nephropathy is a life-threatening complication in patients with long-standing diabetes. Hemodynamic, inflammatory, and metabolic factors are considered as developmental factors for diabetic nephropathy. In this study, we evaluated whether pharmacological interventions with salicylate, compared to p...

journal_title：Journal of diabetes research

authors： Abouzed TK,Munesue S,Harashima A,Masuo Y,Kato Y,Khailo K,Yamamoto H,Yamamoto Y

更新日期：2016-01-01 00:00:00

abstract：:We aimed to clarify how the trajectories of 1-hour postload plasma glucose (PG) and 2-hour PG were different in the development of type 2 diabetes. Using data of repeated health checkups in Japanese workers from April 2006 to March 2016, longitudinal changes of fasting, 1-hour, and 2-hour PG on the oral glucose tolera...

journal_title：Journal of diabetes research

authors： Oka R,Shibata K,Sakurai M,Kometani M,Yamagishi M,Yoshimura K,Yoneda T

更新日期：2017-01-01 00:00:00

abstract：:Studies have documented that the pathogenesis of autoimmune diabetes is influenced by the intake of gluten. Aims. To investigate the importance of gluten exposure during pregnancy and the subsequent development of autoimmune diabetes in offspring. Methods. Nonobese diabetic mice were divided into 7 groups to receive c...

journal_title：Journal of diabetes research

authors： Antvorskov JC,Josefsen K,Haupt-Jorgensen M,Fundova P,Funda DP,Buschard K

更新日期：2016-01-01 00:00:00

abstract：:Mitogen inducible gene-6 (Mig-6) is a feedback inhibitor of epidermal growth factor receptor (EGFR) signaling pathway. The liver-specific knockout mice of the Mig-6 gene (Mig-6 d/d ) showed hepatomegaly and increased hypercholesterolemia. In this study, the biomarkers of i...

journal_title：Journal of diabetes research

authors： Park BK,Lee EA,Kim HY,Lee JC,Kim KS,Jeong WH,Kim KY,Ku BJ,Rhee SD

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:To investigate the hospital-based incidence of FT1D in Chinese children and compare the clinical feature with classical T1DM. METHODS:A cross-sectional study with sixteen hospitals involved. We obtained 23 FT1D cases as group 1, acute-onset T1DM as group 2, and typical T1DM as group 3. RESULTS:The incidenc...

journal_title：Journal of diabetes research

authors： Gu Y,Wang Y,Li P,Wei H,Chen L,Liu Q,Liu Y,Yang Q,Cheng X,He L,Wei L,Zhu Z,Chen Y,Wang F,Shi X,Cheng Y,Wei Y,Yu J,Gong C

更新日期：2017-01-01 00:00:00