Gluten-Free Diet Only during Pregnancy Efficiently Prevents Diabetes in NOD Mouse Offspring.

abstract：:This study evaluated the inflammatory markers in prediabetes and newly diagnosed type 2 diabetes mellitus (T2DM). Inflammatory markers levels were analyzed using one-way analysis of covariance and the association with prediabetes or T2DM risks was examined by logistic regression models. Our data showed increased level...

journal_title：Journal of diabetes research

authors： Wang Z,Shen XH,Feng WM,Ye GF,Qiu W,Li B

更新日期：2016-01-01 00:00:00

abstract：:To understand features of human obesity and type 2 diabetes mellitus (T2D) that can be recapitulated in the mouse, we compared C57BL/6J mice fed a Western-style diet (WD) to weight-matched genetically obese leptin receptor-deficient mice (db/db). All mice were monitored for changes in body composition, glycemia, and t...

journal_title：Journal of diabetes research

authors： Burke SJ,Batdorf HM,Burk DH,Noland RC,Eder AE,Boulos MS,Karlstad MD,Collier JJ

更新日期：2017-01-01 00:00:00

abstract：:Diabetes mellitus is a chronic disease prevalence of which is high and continually growing. Cardiovascular disease continues to be the leading cause of death in patients with T2DM. The prevention of cardiovascular complications and the cardiovascular safety of treatments should be a primary objective when selecting tr...

journal_title：Journal of diabetes research

authors： Del Olmo-Garcia MI,Merino-Torres JF

更新日期：2018-04-02 00:00:00

abstract：Background:Diabetes mellitus (DM) has become one of the most common chronic metabolic diseases worldwide. Due to the increasing prevalence and various complications, diabetes brings about a huge financial burden to DM patients. Nowadays, more and more studies reveal the relationship between diseases and gut microbial c...

journal_title：Journal of diabetes research

authors： Zhao X,Zhang Y,Guo R,Yu W,Zhang F,Wu F,Shang J

更新日期：2020-11-11 00:00:00

abstract：Objectives:To investigate the risk factors for cognitive impairment in Chinese type 2 diabetes mellitus (T2DM) patients of advanced age and to identify effective biomarkers of mild cognitive impairment (MCI) in these patients. Methods:Chinese T2DM patients (n = 120) aged 50-70 years were divided into groups with impai...

journal_title：Journal of diabetes research

authors： Sun L,Diao X,Gang X,Lv Y,Zhao X,Yang S,Gao Y,Wang G

更新日期：2020-04-23 00:00:00

abstract：Purpose:Pancreatic stone protein/regenerating protein I (PSP/REG Iα) is a secretory protein mainly detected in the pancreas. Recent studies revealed increased serum PSP/REG Iα) is a secretory protein mainly detected in the pancreas. Recent studies revealed increased serum PSP/REG Iα) is a secretory protein mainly detec...

journal_title：Journal of diabetes research

authors： Zhu H,Zhu X,Lin H,Liu D,Dai Y,Su X,Li L

更新日期：2020-03-23 00:00:00

abstract：:Methylglyoxal (MG) is a highly reactive glucose metabolic intermediate and a major precursor of advanced glycation end products. MG level is elevated in hyperglycemic disorders such as diabetes mellitus. Substantial evidence has shown that MG is involved in the pathogenesis of diabetes and diabetic complications. We i...

journal_title：Journal of diabetes research

authors： Bo J,Xie S,Guo Y,Zhang C,Guan Y,Li C,Lu J,Meng QH

更新日期：2016-01-01 00:00:00

abstract：:Background. The aim of this study was to validate the impact of type 2 diabetes (T2D) on the platelet reactivity in patients with acute ST elevation myocardial infarction (STEMI) treated with adenosine diphosphate (ADP) receptor blockers. Methods. A pilot prospective study was performed. Totally 67 patients were enrol...

journal_title：Journal of diabetes research

authors： Samoš M,Fedor M,Kovář F,Galajda P,Bolek T,Stančiaková L,Fedorová J,Staško J,Kubisz P,Mokáň M

更新日期：2016-01-01 00:00:00

abstract：:We investigated effects on glucose and lipid metabolism in combination of JTT-130, a novel intestine-specific microsomal triglyceride transfer protein (MTP) inhibitor, and pioglitazone, peroxisome proliferator-activated receptor (PPAR) γ agonist. Male Zucker diabetic fatty rats were divided into 4 groups: control grou...

journal_title：Journal of diabetes research

authors： Sakata S,Mera Y,Kuroki Y,Nashida R,Kakutani M,Ohta T

更新日期：2014-01-01 00:00:00

abstract：:Diabetes mellitus is a metabolic disorder which is characterized by multiple long-term complications that affect almost every system in the body. Foot ulcers are one of the main complications of diabetes mellitus. However, there is limited evidence on the occurrence of foot ulcer and influencing factors in Ethiopia. A...

journal_title：Journal of diabetes research

authors： Mariam TG,Alemayehu A,Tesfaye E,Mequannt W,Temesgen K,Yetwale F,Limenih MA

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:Glucagon-like peptide-1 (GLP-1) analogues (e.g., exenatide) increase insulin secretion in diabetes but less is known about their effects on glucose production or insulin-stimulated glucose uptake in peripheral tissues. METHODS:Four groups of Sprague-Dawley rats were studied: nondiabetic (control, C); nondiab...

journal_title：Journal of diabetes research

authors： Wu H,Sui C,Xu H,Xia F,Zhai H,Zhang H,Weng P,Han B,Du S,Lu Y

更新日期：2014-01-01 00:00:00

abstract：:The abnormal fibrillation of human islet amyloid polypeptide (hIAPP) has been implicated in the development of type II diabetes. Aluminum is known to trigger the structural transformation of many amyloid proteins and induce the formation of toxic aggregate species. The (-)-epigallocatechin gallate (EGCG) is considered...

journal_title：Journal of diabetes research

authors： Xu ZX,Zhang Q,Ma GL,Chen CH,He YM,Xu LH,Zhang Y,Zhou GR,Li ZH,Yang HJ,Zhou P

更新日期：2016-01-01 00:00:00

abstract：:Tripterygium glycosides tablet (TGT) is a Chinese traditional medicine that has been shown to protect podocytes from injury and reduce the proteinuria. The aim of this study was to assess the effect of TGT on renal tubulointerstitial fibrosis and its potential mechanism in high-fat diet fed and STZ-induced diabetic ra...

journal_title：Journal of diabetes research

authors： Ma ZJ,Zhang XN,Li L,Yang W,Wang SS,Guo X,Sun P,Chen LM

更新日期：2015-01-01 00:00:00

abstract：:To compare the efficacy and safety of metformin, glyburide, and insulin in treating gestational diabetes mellitus (GDM), a meta-analysis of randomized controlled trials (RCTs) was conducted. PubMed, Embase, CINAHL, Web of Science, and Cochrane Library to November 13, 2018, were searched for RCT adjusted estimates of t...

journal_title：Journal of diabetes research

authors： Guo L,Ma J,Tang J,Hu D,Zhang W,Zhao X

更新日期：2019-11-04 00:00:00

abstract：Aim:To evaluate the influence of metabolic parameters and the treatment method in children with type 1 diabetes (T1D) on the optical coherence tomography angiography (OCTA) results as early markers of diabetic retinopathy (DR). Material and Methods. This prospective study enrolled 175 consecutive children with T1D. OCT...

journal_title：Journal of diabetes research

authors： Wysocka-Mincewicz M,Baszyńska-Wilk M,Gołębiewska J,Olechowski A,Byczyńska A,Hautz W,Szalecki M

更新日期：2020-11-18 00:00:00

abstract：:Many studies have assessed the association between eNOS-4b/a polymorphism and the risk of diabetic retinopathy (DR) among type 2 diabetic subjects. However, the results are inconsistent. In order to derive a more precise estimation of the association, a meta-analysis was conducted. Fifteen studies with 3, 183 cases an...

journal_title：Journal of diabetes research

authors： Ma ZJ,Chen R,Ren HZ,Guo X,Guo J,Chen LM

更新日期：2014-01-01 00:00:00

abstract：:We investigated the effects of teneligliptin on uric acid metabolism in male Wistar rats and 3T3-L1 adipocytes. The rats were fed with a normal chow diet (NCD) or a 60% high-fat diet (HFD) with or without teneligliptin for 4 weeks. The plasma uric acid level was not significantly different between the control and tene...

journal_title：Journal of diabetes research

authors： Moriya C,Satoh H

更新日期：2016-01-01 00:00:00

abstract：Background:The risk factors for acute kidney injury (AKI) development in patients with diabetes hospitalized for COVID-19 have not been fully studied yet. In this study, we aimed to estimate the rate of AKI among the hospitalized population with COVID-19 and to identify the risk factors associated with AKI among patien...

journal_title：Journal of diabetes research

authors： Khalili S,Sabaghian T,Sedaghat M,Soroureddin Z,Askari E,Khalili N

更新日期：2021-01-06 00:00:00

abstract：Introduction:The aim of the present study was to examine placental levels of DUSP9 mRNA and protein and to investigate the potential role of DUSP9 in the development of gestational diabetes mellitus (GDM). Methods:Placental tissues from pregnant women with GDM (n = 17) and normal healthy pregnant women (n = 16) were c...

journal_title：Journal of diabetes research

authors： Wei Q,Pu X,Zhang L,Xu Y,Duan M,Wang Y

更新日期：2019-10-20 00:00:00

abstract：:Glucokinase (GK) plays a critical role in the control of whole-body glucose homeostasis. We investigated the possible effects of a novel glucokinase activator (GKA), HMS5552, to the GK in rats with type 2 diabetes mellitus (T2DM). Male Sprague-Dawley (SD) rats were divided into four groups: control group, diabetic gro...

journal_title：Journal of diabetes research

authors： Wang P,Liu H,Chen L,Duan Y,Chen Q,Xi S

更新日期：2017-01-01 00:00:00

abstract：Background:In T1DM, delayed pubertal development and reduced final height are associated with inadequate metabolic control. Objective:To assess whether T1DM affects pubertal growth spurt and whether metabolic control during puberty is gender-related. Methods:Using a large multicentre database, longitudinal data from ...

journal_title：Journal of diabetes research

authors： Plamper M,Gohlke B,Woelfle J,Konrad K,Rohrer T,Hofer S,Bonfig W,Fink K,Holl RW

更新日期：2017-01-01 00:00:00

abstract：:Poor maternal glycemic control increases maternal and fetal risk for adverse outcomes, and strict management of gestational diabetes mellitus (GDM) is recommended to prevent neonatal and maternal complications. However, risk factors for the requirement of antenatal insulin treatment (AIT) are not well-investigated in ...

journal_title：Journal of diabetes research

authors： Watanabe M,Katayama A,Kagawa H,Ogawa D,Wada J

更新日期：2016-01-01 00:00:00

abstract：Objective:The aim of the study was to investigate the independent and combined effects of the cortisol-to-cortisone ratio (F/E) and 11-deoxycortisol on prediabetes and type 2 diabetes mellitus (T2DM) among different genders. Methods:A case-control study was performed including 2676 participants from the Henan Rural Co...

journal_title：Journal of diabetes research

authors： Liu X,Jiang J,Liu X,Luo Z,Wang Y,Dong X,Wei D,Huo W,Yu S,Li L,Jin S,Wang C,Mao Z

更新日期：2019-06-02 00:00:00

abstract：AIMS:Elevated pulse pressure (PP) has been reported to be a risk factor for type 2 diabetes in elderly patients with hypertension. METHODS:Cross-sectional relationships of PP with known risk factors for type 2 diabetes and inflammatory markers were examined in 150 elderly community-dwelling women, 79 women (52.7%) of ...

journal_title：Journal of diabetes research

authors： Yamada E,Takeuchi M,Kurata M,Kazumi T,Fukuo K

更新日期：2014-01-01 00:00:00

abstract：:The complex diagnosis and treatment of diabetes highlight the need for markers to define how to monitor patients correctly during the course of their disease. Different studies demonstrate the existence of patients who cannot be clearly classified. We have previously shown that it is possible to differentiate "atypica...

journal_title：Journal of diabetes research

authors： Fabregat M,Fernandez M,Javiel G,Vitarella G,Mimbacas A

更新日期：2015-01-01 00:00:00

abstract：Background:Diabetic retinopathy (DR) is a severe complication of diabetes mellitus. DR is considered as a neurovascular disease. Retinal ganglion cell (RGC) loss plays an important role in the vision function disorder of diabetic patients. Histone deacetylase3 (HDAC3) is closely related to injury repair and nerve regen...

journal_title：Journal of diabetes research

authors： Fu Y,Wang Y,Gao X,Li H,Yuan Y

更新日期：2020-03-01 00:00:00

abstract：:Diabetes mellitus (DM) is a major worldwide health problem and its prevalence has been rapidly increasing in the last century. It is caused by defects in insulin secretion or insulin action or both, leading to hyperglycemia. Of the various types of DM, type 2 occurs most frequently. Multiple genes and their interactio...

journal_title：Journal of diabetes research

authors： Haghvirdizadeh P,Mohamed Z,Abdullah NA,Haghvirdizadeh P,Haerian MS,Haerian BS

更新日期：2015-01-01 00:00:00

abstract：Background:Diabetes mellitus is a widely diffused chronic condition which impacts on several aspects of patients' lives. In the current clinical practice, the implementation in the clinical routine of monitoring systems of patients' outcomes has led to an increased generation and use of several measures for the assessm...

journal_title：Journal of diabetes research

authors： Palamenghi L,Carlucci MM,Graffigna G

更新日期：2020-05-20 00:00:00

abstract：:Type 2 diabetes mellitus (T2DM) belongs to the diseases with hereditary predisposition, so both environmental and genetic factors contribute to its development. Recent studies have demonstrated that the skeleton realizes systemic regulation of energy metabolism through the secretion of osteocalcin (OCN). Thus, the ass...

journal_title：Journal of diabetes research

authors： Chumachenko YD,Harbuzova VY,Ataman AV

更新日期：2019-11-27 00:00:00

abstract：:The proliferation of vascular smooth muscle cells (VSMCs) is one of the main features of atherosclerosis induced by high glucose. Mevalonate pathway is an important metabolic pathway that plays a key role in multiple cellular processes. The aim of this study was to define whether the enzyme expression in mevalonate pa...

journal_title：Journal of diabetes research

authors： Chen GP,Zhang XQ,Wu T,Li L,Han J,Du CQ

更新日期：2015-01-01 00:00:00