Abstract:
Background:The risk factors for acute kidney injury (AKI) development in patients with diabetes hospitalized for COVID-19 have not been fully studied yet. In this study, we aimed to estimate the rate of AKI among the hospitalized population with COVID-19 and to identify the risk factors associated with AKI among patients with diabetes. Material and Methods. This retrospective cohort study included 254 patients (127 with diabetes and 127 without diabetes) who were admitted for COVID-19 to a tertiary hospital in Tehran, Iran, between February and May 2020. Clinical characteristics and outcomes, radiological findings, and laboratory data, including data on AKI, hematuria, and proteinuria were recorded and analyzed. Results:Of 254 patients, 142 (55.9%) were male and the mean (± SD) age was 65.7 years (±12.5). In total, 58 patients (22.8%) developed AKI during hospitalization, of whom 36 patients had diabetes (p = 0.04); most patients (74.1%) had stage 1 or 2 AKI. Also, 8 patients (13.8%) required renal replacement therapy (RRT) after developing AKI. Regardless of diabetes status, patients who developed AKI had significantly higher mortality rates compared with patients who did not develop AKI (p = 0.02). Hematuria and proteinuria were observed in 38.1% and 55% of patients, respectively. Multivariate analysis showed that invasive mechanical ventilation, proteinuria, HBA1c level, history of cardiovascular disease, and use of statins were independent risk factors for AKI development in patients with diabetes. Conclusion:Results of this study showed that AKI develops in a considerable percentage of patients with COVID-19, especially in those with diabetes, and is significantly associated with mortality.
journal_name
J Diabetes Resjournal_title
Journal of diabetes researchauthors
Khalili S,Sabaghian T,Sedaghat M,Soroureddin Z,Askari E,Khalili Ndoi
10.1155/2021/6666086subject
Has Abstractpub_date
2021-01-06 00:00:00pages
6666086eissn
2314-6745issn
2314-6753journal_volume
2021pub_type
杂志文章abstract:Background:The effective hemostasis after minor debridement in an outpatient clinic is important and essential. This study is aimed at evaluating the hemostatic efficacy and safety of the kaolin-impregnated dressing for diabetic foot ulcer patient who take an anticoagulant. Methods:A prospective, randomized, clinical ...
journal_title:Journal of diabetes research
pub_type: 杂志文章,随机对照试验
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journal_title:Journal of diabetes research
pub_type: 杂志文章
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journal_title:Journal of diabetes research
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journal_title:Journal of diabetes research
pub_type: 杂志文章
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更新日期:2020-12-02 00:00:00
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journal_title:Journal of diabetes research
pub_type: 杂志文章
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journal_title:Journal of diabetes research
pub_type: 临床试验,杂志文章
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journal_title:Journal of diabetes research
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journal_title:Journal of diabetes research
pub_type: 杂志文章
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journal_title:Journal of diabetes research
pub_type: 杂志文章,随机对照试验
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更新日期:2015-01-01 00:00:00
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journal_title:Journal of diabetes research
pub_type: 杂志文章,meta分析
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journal_title:Journal of diabetes research
pub_type: 杂志文章,评审
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journal_title:Journal of diabetes research
pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2020-11-24 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Journal of diabetes research
pub_type: 杂志文章,已发布勘误
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更新日期:2018-10-22 00:00:00