Social Support Groups in the Maintenance of Glycemic Control after Community-Based Intervention.

abstract：:Mannan-binding lectin (MBL) has been reported to be involved in the pathophysiology of diabetic nephropathy. MBL is a pattern-recognition molecule of the innate immune system that initiates the lectin pathway of the complement system upon recognition of evolutionary conserved pathogen-associated molecular patterns or ...

journal_title：Journal of diabetes research

authors： Axelgaard E,Østergaard JA,Thiel S,Hansen TK

更新日期：2017-01-01 00:00:00

abstract：:The haptoglobin (Hp) genotype (1-1 and 2-2) is a major determinant of nephropathy progression in diabetes mellitus patients. Hp 2-2 diabetic mice have impaired Hb clearance and increased iron deposits and oxidative stress in the proximal tubules (PCT), leading to increased renal injury. However, the precise mechanism ...

journal_title：Journal of diabetes research

authors： Dahan I,Thawho N,Farber E,Nakhoul N,Asleh R,Levy AP,Li YC,Ben-Izhak O,Nakhoul F

更新日期：2018-09-03 00:00:00

abstract：:The kidney is an insulin-sensitive organ involved in glucose homeostasis. One major effect of insulin is to induce glycogen storage in the liver and muscle. However, no significant glycogen stores are detected in normal kidneys, but diabetic subjects present a characteristic renal histopathological feature resulting f...

journal_title：Journal of diabetes research

authors： Bertinat R,Westermeier F,Silva P,Gatica R,Oliveira JM,Nualart F,Gomis R,Yáñez AJ

更新日期：2018-05-29 00:00:00

abstract：:Diabetic polyneuropathy (DPN) is the most frequent and prevalent chronic complication of diabetes mellitus (DM). The state of persistent hyperglycemia leads to an increase in the production of cytosolic and mitochondrial reactive oxygen species (ROS) and favors deregulation of the antioxidant defenses that are capable...

journal_title：Journal of diabetes research

authors： Sifuentes-Franco S,Pacheco-Moisés FP,Rodríguez-Carrizalez AD,Miranda-Díaz AG

更新日期：2017-01-01 00:00:00

abstract：Background:Previous studies showed that probiotics could improve glycemic control and attenuate some of the adverse effects of type 2 diabetes. However, whether the effects are generalizable to gestational diabetes mellitus (GDM) remains uncertain. Objective:We conducted a systematic review and meta-analysis to evalua...

journal_title：Journal of diabetes research

authors： Zhang J,Ma S,Wu S,Guo C,Long S,Tan H

更新日期：2019-09-05 00:00:00

abstract：:We investigated the association of serum homocysteine levels and vitamin status with type 2 diabetic retinopathy. This study included 65 patients with and 75 patients without diabetic retinopathy. Patients with diabetic retinopathy had significantly higher serum homocysteine levels (P < 0.001), higher prevalence of hy...

journal_title：Journal of diabetes research

authors： Fotiou P,Raptis A,Apergis G,Dimitriadis G,Vergados I,Theodossiadis P

更新日期：2014-01-01 00:00:00

abstract：:The association between diabetes mellitus (DM) and high mortality linked to cardiovascular disease (CVD) is a major concern worldwide. Clinical and preclinical studies have demonstrated a variety of diastolic and systolic dysfunctions in patients with type 2 diabetes mellitus (T2DM) with the severity of abnormalities ...

journal_title：Journal of diabetes research

authors： Al Kury L,Smail M,Qureshi MA,Sydorenko V,Shmygol A,Oz M,Singh J,Howarth FC

更新日期：2018-04-10 00:00:00

abstract：:The aim of this study was to assess the differences in correlation of PPARGC1A polymorphisms with type 2 diabetes (T2D) risk in adults of African origins: African Americans and Haitian Americans. The case-control study consisted of >30 years old, self-identified Haitian Americans (n = 110 cases and n = 116 controls) a...

journal_title：Journal of diabetes research

authors： Cheema AK,Li T,Liuzzi JP,Zarini GG,Dorak MT,Huffman FG

更新日期：2015-01-01 00:00:00

abstract：AIMS AND BACKGROUND:Type 2 diabetes is a chronic disease that cannot be treated adequately using the known monotherapies, especially when the disease progresses to an advanced stage. In this study, we explore the possibility of treating the disease with a novel combination approach of oleanolic acid (OA), a glycogen ph...

journal_title：Journal of diabetes research

authors： Wang X,Chen Y,Abdelkader D,Hassan W,Sun H,Liu J

更新日期：2015-01-01 00:00:00

abstract：AIMS:Elevated pulse pressure (PP) has been reported to be a risk factor for type 2 diabetes in elderly patients with hypertension. METHODS:Cross-sectional relationships of PP with known risk factors for type 2 diabetes and inflammatory markers were examined in 150 elderly community-dwelling women, 79 women (52.7%) of ...

journal_title：Journal of diabetes research

authors： Yamada E,Takeuchi M,Kurata M,Kazumi T,Fukuo K

更新日期：2014-01-01 00:00:00

abstract：:Studies have documented that the pathogenesis of autoimmune diabetes is influenced by the intake of gluten. Aims. To investigate the importance of gluten exposure during pregnancy and the subsequent development of autoimmune diabetes in offspring. Methods. Nonobese diabetic mice were divided into 7 groups to receive c...

journal_title：Journal of diabetes research

authors： Antvorskov JC,Josefsen K,Haupt-Jorgensen M,Fundova P,Funda DP,Buschard K

更新日期：2016-01-01 00:00:00

abstract：:The role of diabetic nephropathy in the outcome of acute renal injury (AKI) is not well defined. Herein we evaluate the outcome of lipopolysaccharide- (LPS-) induced AKI in streptozotocin-induced diabetes, as well as the potential role of Hypoxia Inducible Factor (HIF-1 α ) in this condition. Although 6 h after LPS in...

journal_title：Journal of diabetes research

authors： Ortega A,Fernández A,Arenas MI,López-Luna P,Muñóz-Moreno C,Arribas I,Olea N,García-Bermejo L,Lucio-Cazana J,Bosch RJ

更新日期：2013-01-01 00:00:00

abstract：:miR-122, the expression of which is regulated by several transcription factors, such as HNF1A, was recently reported to be associated with type 2 diabetes (T2DM) and hepatocellular carcinoma. HNF1A variants can cause diabetes and might be involved in the development of primary liver neoplasm. Differences in miR-122 ex...

journal_title：Journal of diabetes research

authors： Huang X,Gong S,Ma Y,Cai X,Zhou L,Luo Y,Li M,Liu W,Zhang S,Zhang X,Ren Q,Zhu Y,Zhou X,Zhang R,Chen L,Gao X,Zhang F,Wang Y,Han X,Ji L

更新日期：2018-08-01 00:00:00

abstract：:Dilated cardiomyopathy (DCM) is characterized by a metabolic shift from fat to carbohydrates and failure to increase myocardial glucose uptake in response to workload increments. We verified whether this pattern is influenced by an abnormal glucose tolerance (AGT). In 10 patients with DCM, 5 with normal glucose tolera...

journal_title：Journal of diabetes research

authors： Tricò D,Baldi S,Frascerra S,Venturi E,Marraccini P,Neglia D,Natali A

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:Glucagon-like peptide-1 (GLP-1) analogues (e.g., exenatide) increase insulin secretion in diabetes but less is known about their effects on glucose production or insulin-stimulated glucose uptake in peripheral tissues. METHODS:Four groups of Sprague-Dawley rats were studied: nondiabetic (control, C); nondiab...

journal_title：Journal of diabetes research

authors： Wu H,Sui C,Xu H,Xia F,Zhai H,Zhang H,Weng P,Han B,Du S,Lu Y

更新日期：2014-01-01 00:00:00

abstract：Aims:The purpose of the present research is to investigate the effects of the VHL protein antagonist, VH298, on functional activities of fibroblasts and vascular endothelial cells and the effects on the wound healing process in a streptozotocin-induced hyperglycaemic rat model. Methods:HIF-1α and hydroxy-HIF-1α protei...

journal_title：Journal of diabetes research

authors： Qiu S,Jia Y,Sun Y,Han P,Xu J,Wen G,Chai Y

更新日期：2019-02-17 00:00:00

abstract：Objective:To investigate the effects of cod-liver oil on metabolic status and high-sensitivity C-reactive protein (hs-CRP) in patients with gestational diabetes mellitus (GDM). Methods:This study was a randomized, double-blinded, placebo-controlled trial with the allocation ratio of 1 : 1. The contents of EPA and DHA ...

journal_title：Journal of diabetes research

authors： Yang S,Lin R,Si L,Li Z,Jian W,Yu Q,Jia Y

更新日期：2019-12-28 00:00:00

abstract：:Glucokinase (GK) plays a critical role in the control of whole-body glucose homeostasis. We investigated the possible effects of a novel glucokinase activator (GKA), HMS5552, to the GK in rats with type 2 diabetes mellitus (T2DM). Male Sprague-Dawley (SD) rats were divided into four groups: control group, diabetic gro...

journal_title：Journal of diabetes research

authors： Wang P,Liu H,Chen L,Duan Y,Chen Q,Xi S

更新日期：2017-01-01 00:00:00

abstract：:Forefoot load (FL) contributes to callus formation, which is one of the pathways to diabetic foot ulcers (DFU). In this study, we hypothesized that excessive FL, which cannot be detected by plantar load measurements within laboratory settings, occurs in daily walks. To demonstrate this, we created a FL estimation algo...

journal_title：Journal of diabetes research

authors： Watanabe A,Noguchi H,Oe M,Sanada H,Mori T

更新日期：2017-01-01 00:00:00

abstract：Objective:The aim of this study was to explore the association of 1,5-anhydroglucitol with acute C peptide response (ACPR) to arginine among patients with type 2 diabetes. Methods:Patients with type 2 diabetes were enrolled from the Department of Endocrinology and Metabolism, Shanghai Sixth People's Hospital. ACPR was...

journal_title：Journal of diabetes research

authors： Shen Y,Si Y,Lu J,Ma X,Zhang L,Mo Y,Lu W,Zhu W,Bao Y,Hu G,Zhou J

更新日期：2020-07-21 00:00:00

abstract：:Knowing how to prevent and treat diabetes mellitus (DM) earlier is essential to improving outcomes. Through participating in synthesis and catabolism of glycogen, the liver helps to regulate glucose homeostasis. Viral related liver diseases are associated with glycometabolism disorders, which means effective managemen...

journal_title：Journal of diabetes research

authors： Zhao Y,Xing H

更新日期：2017-01-01 00:00:00

abstract：:To study the relationship between glycosylated hemoglobin (HgbA1c) and myocardial perfusion in type 2 diabetes mellitus (T2DM) patients, we prospectively enrolled 24 patients with known or suspected coronary artery disease (CAD) who underwent adenosine stress by real-time myocardial perfusion echocardiography (RTMPE)....

journal_title：Journal of diabetes research

authors： Huang R,Abdelmoneim SS,Nhola LF,Mulvagh SL

更新日期：2014-01-01 00:00:00

abstract：:Aims. Prevention of diabetes complications depends on the level of case finding and successful treatment of diabetes, which may differ between ethnicities. Therefore, we studied the prevalence by age, awareness, treatment, and control of type 2 diabetes, among a multiethnic population. Methods. We included 4,541 Dutch...

journal_title：Journal of diabetes research

authors： Snijder MB,Agyemang C,Peters RJ,Stronks K,Ujcic-Voortman JK,van Valkengoed IG

更新日期：2017-01-01 00:00:00

abstract：:According to the American Diabetes Association (ADA), the side effects of diabetes mellitus have recently increased the global health expenditure each year. Of these, the early diagnostic can contribute to the decrease on renal, cardiovascular, and nervous systems complications. However, the diagnostic criteria, which...

journal_title：Journal of diabetes research

authors： Arroyo-Carmona RE,López-Serrano AL,Albarado-Ibañez A,Mendoza-Lucero FM,Medel-Cajica D,López-Mayorga RM,Torres-Jácome J

更新日期：2016-01-01 00:00:00

abstract：:Aim. To investigate corneal endothelial cell morphological in children with type 1 diabetes and to determine the systemic and local factors that contribute to these changes. Methods. One hundred sixty eyes of 80 children with type 1 diabetes and 80 eyes of 40 normal children as a control during the period from July 20...

journal_title：Journal of diabetes research

authors： Anbar M,Ammar H,Mahmoud RA

更新日期：2016-01-01 00:00:00

abstract：:Angiotensin-(1-7) [Ang-(1-7)] may have beneficial effects in diabetes mellitus-induced erectile dysfunction (DMIED) but its molecular actions in the diabetic corpus cavernosum (CC) are not known. We characterized the effects of diabetes and/or chronic in vivo administration of Ang-(1-7) on vascular reactivity in the r...

journal_title：Journal of diabetes research

authors： Yousif MH,Makki B,El-Hashim AZ,Akhtar S,Benter IF

更新日期：2014-01-01 00:00:00

abstract：:Tripterygium glycosides tablet (TGT) is a Chinese traditional medicine that has been shown to protect podocytes from injury and reduce the proteinuria. The aim of this study was to assess the effect of TGT on renal tubulointerstitial fibrosis and its potential mechanism in high-fat diet fed and STZ-induced diabetic ra...

journal_title：Journal of diabetes research

authors： Ma ZJ,Zhang XN,Li L,Yang W,Wang SS,Guo X,Sun P,Chen LM

更新日期：2015-01-01 00:00:00

abstract：:Objectives. To compare the prevalence of diabetic peripheral neuropathy (DPN) and that of cardiac autonomic neuropathy (CAN) between South Asians and White Caucasians with type 2 diabetes and to explore reasons for observed differences. Methods. A cross-sectional study of casually selected South Asian and White Caucas...

journal_title：Journal of diabetes research

authors： Tahrani AA,Altaf QA,Piya MK,Barnett AH

更新日期：2017-01-01 00:00:00

abstract：Background/Aims:It is known that chronic low-grade inflammation contributes to the initiation and development of both diabetes and diabetic nephropathy (DN), so we designed this study to investigate the role of P2X7R and NLRP3 inflammasome in DN pathogenesis and the antagonistic effects of artificially cultivated Ophio...

journal_title：Journal of diabetes research

authors： Wang C,Hou XX,Rui HL,Li LJ,Zhao J,Yang M,Sun LJ,Dong HR,Cheng H,Chen YP

更新日期：2018-11-11 00:00:00

abstract：:T2DM patients demonstrate reduced GLP-1 receptor (GLP-1R) expression in their gastric glands. Whether induced T2DM and T1DM differently affect the gastric GLP-1R expression is not known. This study assessed extrapancreatic GLP-1R system in glandular stomach of rodents with different types of experimental diabetes. T2D...

journal_title：Journal of diabetes research

authors： Bloch O,Broide E,Ben-Yehudah G,Cantrell D,Shirin H,Rapoport MJ

更新日期：2015-01-01 00:00:00