Comorbidities and Ethnocultural Factors Limit the Physical Activity of Rural Sri Lankan Patients with Diabetes Mellitus.

abstract：:We studied the use, uptake, and effects of e-Vita, a personal health record, with self-management support and personalized asynchronized coaching, for type 2 diabetes patients treated in primary care. Patients were invited by their practice nurse to join the study aimed at testing use and effects of a personal health ...

journal_title：Journal of diabetes research

authors： van Vugt M,de Wit M,Sieverink F,Roelofsen Y,Hendriks SH,Bilo HJ,Snoek FJ

更新日期：2016-01-01 00:00:00

abstract：:Gastric emptying and glycemic control pathways are closely interrelated processes. Gastric chyme is transferred into the duodenum with velocities depending on its solid or liquid state, as well as on its caloric and nutritional composition. Once nutrients enter the intestine, the secretion of incretins (hormonal produ...

journal_title：Journal of diabetes research

authors： Mihai BM,Mihai C,Cijevschi-Prelipcean C,Grigorescu ED,Dranga M,Drug V,Sporea I,Lăcătușu CM

更新日期：2018-10-03 00:00:00

abstract：:Most patients with type 2 diabetes (T2D) have suboptimal adherence to recommended diet, physical activity, and/or medication. Current approaches to improve health behaviors in T2D have been variably effective, and successful interventions are often complex and intensive. It is therefore vital to develop interventions ...

journal_title：Journal of diabetes research

authors： Huffman JC,DuBois CM,Millstein RA,Celano CM,Wexler D

更新日期：2015-01-01 00:00:00

abstract：Purpose:We aimed to assess the changes of retinal microvascular parameters using optical coherence tomography angiography (OCTA) between diabetes macular edema (DME) and controls. We assessed the changes between the baseline microvascular parameters and final treatment response in patients with DME, initially treated w...

journal_title：Journal of diabetes research

authors： Park YG,Park YH

更新日期：2020-11-16 00:00:00

abstract：:Inhibition of the potassium channels TREK-1 by spadin (SPA) is currently thought to be a promising therapeutic target for the treatment of depression. Since these channels are expressed in pancreatic β-cells, we investigated their role in the control of insulin secretion and glucose homeostasis. In this study, we conf...

journal_title：Journal of diabetes research

authors： Hivelin C,Béraud-Dufour S,Devader C,Abderrahmani A,Moreno S,Moha Ou Maati H,Djillani A,Heurteaux C,Borsotto M,Mazella J,Coppola T

更新日期：2016-01-01 00:00:00

abstract：:More than 65 loci, encoding up to 500 different genes, have been implicated by genome-wide association studies (GWAS) as conferring an increased risk of developing type 2 diabetes (T2D). Whilst mouse models have in the past been central to understanding the mechanisms through which more penetrant risk genes for T2D, f...

journal_title：Journal of diabetes research

authors： da Silva Xavier G,Bellomo EA,McGinty JA,French PM,Rutter GA

更新日期：2013-01-01 00:00:00

abstract：Background:Obesity has been considered as an important factor in the development and progression of chronic kidney diseases (CKD). Perirenal fat, which is surrounding the kidneys, has been reported to be unique in anatomy and biological functions. This study is aimed at assessing the relationship between perirenal fat ...

journal_title：Journal of diabetes research

authors： Fang Y,Xu Y,Yang Y,Liu C,Zhao D,Ke J

更新日期：2020-06-28 00:00:00

abstract：:Diabetes mellitus is a chronic disease prevalence of which is high and continually growing. Cardiovascular disease continues to be the leading cause of death in patients with T2DM. The prevention of cardiovascular complications and the cardiovascular safety of treatments should be a primary objective when selecting tr...

journal_title：Journal of diabetes research

authors： Del Olmo-Garcia MI,Merino-Torres JF

更新日期：2018-04-02 00:00:00

abstract：Aim:To evaluate the influence of metabolic parameters and the treatment method in children with type 1 diabetes (T1D) on the optical coherence tomography angiography (OCTA) results as early markers of diabetic retinopathy (DR). Material and Methods. This prospective study enrolled 175 consecutive children with T1D. OCT...

journal_title：Journal of diabetes research

authors： Wysocka-Mincewicz M,Baszyńska-Wilk M,Gołębiewska J,Olechowski A,Byczyńska A,Hautz W,Szalecki M

更新日期：2020-11-18 00:00:00

abstract：:Partial or complete remission from type 2 diabetes was recently observed after bariatric surgeries. Limited data is available about the possibility of inducing diabetes remission through intensive weight reduction. We retrospectively evaluated diabetes remissions after one year of the Weight Achievement and Intensive ...

journal_title：Journal of diabetes research

authors： Mottalib A,Sakr M,Shehabeldin M,Hamdy O

更新日期：2015-01-01 00:00:00

abstract：:Knowing how to prevent and treat diabetes mellitus (DM) earlier is essential to improving outcomes. Through participating in synthesis and catabolism of glycogen, the liver helps to regulate glucose homeostasis. Viral related liver diseases are associated with glycometabolism disorders, which means effective managemen...

journal_title：Journal of diabetes research

authors： Zhao Y,Xing H

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Tumor necrosis factor-α-induced protein 8-like 2 (TIPE2 or TNFAIP8L2) is a negative regulator of natural and adaptive immunity. The role of TIPE2 in type 2 diabetes mellitus (T2DM) remains unknown, although TIPE2 plays key roles in preserving inflammatory homeostasis. METHODS:TIPE2 expression was measured b...

journal_title：Journal of diabetes research

authors： Liu Y,Wang X,Zhao Y,Zhao P,Wang L,Zhai Q,Zhang X,Tian W,Xiang X,Li T

更新日期：2017-01-01 00:00:00

abstract：:Glucokinase (GK) plays a critical role in the control of whole-body glucose homeostasis. We investigated the possible effects of a novel glucokinase activator (GKA), HMS5552, to the GK in rats with type 2 diabetes mellitus (T2DM). Male Sprague-Dawley (SD) rats were divided into four groups: control group, diabetic gro...

journal_title：Journal of diabetes research

authors： Wang P,Liu H,Chen L,Duan Y,Chen Q,Xi S

更新日期：2017-01-01 00:00:00

abstract：Background:T2DM may cause increased levels of oxidative stress and cardiac apoptosis through elevated blood glucose. The present study investigated the effects of Lactobacillus plantarum (L. plantarum) as a probiotic strain and inulin as a prebiotic supplement on cardiac oxidative stress and apoptotic markers in type 2...

journal_title：Journal of diabetes research

authors： Sefidgari-Abrasi S,Karimi P,Roshangar L,Morshedi M,Bavafa-Valenlia K,Saghafi-Asl M,Mohiti S,Rahimiyan-Heravan M

更新日期：2020-05-15 00:00:00

abstract：Background:In vivo experiments in Goto-Kakizaki (GK) type 2 diabetic rats have demonstrated reductions in heart rate from a young age. The expression of genes encoding more than 70 proteins that are associated with the generation and conduction of electrical activity in the GK sinoatrial node (SAN) have been evaluated ...

journal_title：Journal of diabetes research

authors： Howarth FC,Qureshi MA,Jayaprakash P,Parekh K,Oz M,Dobrzynski H,Adrian TE

更新日期：2018-09-02 00:00:00

abstract：Background:Chronic overnutrition leads to cardiac dysfunction and insulin (INS) resistance. Dipeptidyl peptidase-4 (DPP-4) improves glucose metabolism and insulin sensitivity in both human and animal models. In this study, we explored whether DPP-4 inhibitor sitagliptin (SIT) is involved in the protection of cardiac fu...

journal_title：Journal of diabetes research

authors： Qiao S,Mao G,Li H,Ma Z,Hong L,Zhang H,Wang C,An J

更新日期：2018-07-17 00:00:00

abstract：Background:Previous studies showed that probiotics could improve glycemic control and attenuate some of the adverse effects of type 2 diabetes. However, whether the effects are generalizable to gestational diabetes mellitus (GDM) remains uncertain. Objective:We conducted a systematic review and meta-analysis to evalua...

journal_title：Journal of diabetes research

authors： Zhang J,Ma S,Wu S,Guo C,Long S,Tan H

更新日期：2019-09-05 00:00:00

abstract：:Previous studies investigating determinants of changes in glycemic status among individuals with prediabetes mainly focused on glucose-defined prediabetes. In this study, we examined determinants of a regression to normoglycemia or a progression to diabetes among individuals with HbA1c-defined prediabetes. The study i...

journal_title：Journal of diabetes research

authors： Paprott R,Scheidt-Nave C,Heidemann C

更新日期：2018-10-14 00:00:00

abstract：Aims:The purpose of the present research is to investigate the effects of the VHL protein antagonist, VH298, on functional activities of fibroblasts and vascular endothelial cells and the effects on the wound healing process in a streptozotocin-induced hyperglycaemic rat model. Methods:HIF-1α and hydroxy-HIF-1α protei...

journal_title：Journal of diabetes research

authors： Qiu S,Jia Y,Sun Y,Han P,Xu J,Wen G,Chai Y

更新日期：2019-02-17 00:00:00

abstract：:The aim of this study was to investigate the relationship between serum 25-hydroxy vitamin D (25-OHD) and insulin sensitivity and β-cell function in newly diagnosed type 2 diabetes. 395 newly diagnosed type 2 diabetes patients were enrolled in this study. Venous blood samples were collected at 0 min, 30 min, and 120 m...

journal_title：Journal of diabetes research

authors： Gao Y,Wu X,Fu Q,Li Y,Yang T,Tang W

更新日期：2015-01-01 00:00:00

abstract：AIMS AND BACKGROUND:Type 2 diabetes is a chronic disease that cannot be treated adequately using the known monotherapies, especially when the disease progresses to an advanced stage. In this study, we explore the possibility of treating the disease with a novel combination approach of oleanolic acid (OA), a glycogen ph...

journal_title：Journal of diabetes research

authors： Wang X,Chen Y,Abdelkader D,Hassan W,Sun H,Liu J

更新日期：2015-01-01 00:00:00

abstract：:The abnormal fibrillation of human islet amyloid polypeptide (hIAPP) has been implicated in the development of type II diabetes. Aluminum is known to trigger the structural transformation of many amyloid proteins and induce the formation of toxic aggregate species. The (-)-epigallocatechin gallate (EGCG) is considered...

journal_title：Journal of diabetes research

authors： Xu ZX,Zhang Q,Ma GL,Chen CH,He YM,Xu LH,Zhang Y,Zhou GR,Li ZH,Yang HJ,Zhou P

更新日期：2016-01-01 00:00:00

abstract：:Type 2 diabetes mellitus is prevalent especially in Gulf countries and poses serious long-term risks to patients. A multifaceted treatment approach can include nutritional supplements with antioxidant properties such as 5-aminolevulinic acid (5-ALA) with sodium ferrous citrate (SFC). This prospective, randomized, sing...

journal_title：Journal of diabetes research

authors： Al-Saber F,Aldosari W,Alselaiti M,Khalfan H,Kaladari A,Khan G,Harb G,Rehani R,Kudo S,Koda A,Tanaka T,Nakajima M,Darwish A

更新日期：2016-01-01 00:00:00

abstract：:Diabetic encephalopathy is a diabetic complication related to the metabolic alterations featuring diabetes. Diabetes is characterized by increased lipid peroxidation, altered glutathione redox status, exacerbated levels of ROS, and mitochondrial dysfunction. Although the pathophysiology of diabetic encephalopathy rema...

journal_title：Journal of diabetes research

authors： Ortiz-Avila O,Esquivel-Martínez M,Olmos-Orizaba BE,Saavedra-Molina A,Rodriguez-Orozco AR,Cortés-Rojo C

更新日期：2015-01-01 00:00:00

abstract：:Aerobic exercise training and weight loss (AEX+WL) improves insulin sensitivity in overweight adults; however, the underlying pathways are incompletely understood. Fetuin-A, a hepatokine that inhibits insulin signaling, may be involved in the salutary effects of AEX+WL. Therefore, we examined the effects of 6-month AE...

journal_title：Journal of diabetes research

authors： Blumenthal JB,Gitterman A,Ryan AS,Prior SJ

更新日期：2017-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2018/6239158.]. ...

journal_title：Journal of diabetes research

authors： Abdella NA,Mojiminiyi OA

更新日期：2018-10-22 00:00:00

abstract：:The association between diabetes mellitus (DM) and high mortality linked to cardiovascular disease (CVD) is a major concern worldwide. Clinical and preclinical studies have demonstrated a variety of diastolic and systolic dysfunctions in patients with type 2 diabetes mellitus (T2DM) with the severity of abnormalities ...

journal_title：Journal of diabetes research

authors： Al Kury L,Smail M,Qureshi MA,Sydorenko V,Shmygol A,Oz M,Singh J,Howarth FC

更新日期：2018-04-10 00:00:00

abstract：:Children with type 1 diabetes (T1DM) are the high-risk group of accelerated atherosclerosis. Real-time continuous glucose monitoring (RT-CGM) provides possibilities for the detection of glycaemic variability, newly recognized cardiovascular risk factor. The aim of the study was to assess the usefulness of RT-CGM as an...

journal_title：Journal of diabetes research

authors： Jamiołkowska M,Jamiołkowska I,Łuczyński W,Tołwińska J,Bossowski A,Głowińska Olszewska B

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Intensive transfusion schedule and iron-chelating therapy prolonged and improved quality of life in patients with β-thalassemia (β-T) major. However, this led to an increased risk of developing impaired glucose tolerance or diabetes. In this study we analyzed variables associated with the occurrence of impai...

journal_title：Journal of diabetes research

authors： Pes GM,Tolu F,Dore MP

更新日期：2016-01-01 00:00:00

abstract：:Mitogen inducible gene-6 (Mig-6) is a feedback inhibitor of epidermal growth factor receptor (EGFR) signaling pathway. The liver-specific knockout mice of the Mig-6 gene (Mig-6 d/d ) showed hepatomegaly and increased hypercholesterolemia. In this study, the biomarkers of i...

journal_title：Journal of diabetes research

authors： Park BK,Lee EA,Kim HY,Lee JC,Kim KS,Jeong WH,Kim KY,Ku BJ,Rhee SD

更新日期：2016-01-01 00:00:00