Effects of Exercise Training and Weight Loss on Plasma Fetuin-A Levels and Insulin Sensitivity in Overweight Older Men.

abstract：:This study determined if blocking ligand occupancy of the αVβ3 integrin could inhibit the pathophysiologic changes that occur in the early stages of diabetic nephropathy (DN). Diabetic rats were treated with either vehicle or a monoclonal antibody that binds the β3 subunit of the αVβ3 integrin. After 4 weeks of diabet...

journal_title：Journal of diabetes research

authors： Maile LA,Gollahon K,Wai C,Dunbar P,Busby W,Clemmons D

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of onsite screening with a nonmydriatic, digital fundus camera for diabetic retinopathy (DR) at a diabetes outpatient clinic. RESEARCH DESIGN AND METHODS:This cross-sectional study included 502 patients, 112 with type 1 and 390 with type 2 diabetes. Patients attended screenings for mic...

journal_title：Journal of diabetes research

authors： Roser P,Kalscheuer H,Groener JB,Lehnhoff D,Klein R,Auffarth GU,Nawroth PP,Schuett F,Rudofsky G

更新日期：2016-01-01 00:00:00

abstract：Objectives:Tetrahydrobiopterin (BH4) pathway that included generation of neopterin (Neop), biopterin (Biop), and nitric oxide (NO) is altered in type 2 diabetes (T2D). The aim of this study was to assess the biomarkers of BH4 pathway in noninfected DFUs and to relate these levels to the variables of diabetes as well as...

journal_title：Journal of diabetes research

authors： Al-Nimer M,Ratha R,Mahwi T

更新日期：2019-11-16 00:00:00

abstract：:Poor maternal glycemic control increases maternal and fetal risk for adverse outcomes, and strict management of gestational diabetes mellitus (GDM) is recommended to prevent neonatal and maternal complications. However, risk factors for the requirement of antenatal insulin treatment (AIT) are not well-investigated in ...

journal_title：Journal of diabetes research

authors： Watanabe M,Katayama A,Kagawa H,Ogawa D,Wada J

更新日期：2016-01-01 00:00:00

abstract：Introduction:The aim of the present study was to examine placental levels of DUSP9 mRNA and protein and to investigate the potential role of DUSP9 in the development of gestational diabetes mellitus (GDM). Methods:Placental tissues from pregnant women with GDM (n = 17) and normal healthy pregnant women (n = 16) were c...

journal_title：Journal of diabetes research

authors： Wei Q,Pu X,Zhang L,Xu Y,Duan M,Wang Y

更新日期：2019-10-20 00:00:00

abstract：:Diabetic nephropathy (DN) is one of the most common causes of end-stage renal failure. This study was performed to determine the effect of Dantonic Pill (DP) treatment on β -catenin expression in a rat model of streptozotocin- (STZ-) induced early-stage DN, with irbesartan treatment as a positive control. Including an...

journal_title：Journal of diabetes research

authors： Shuhong Z,Hongjun L,Bo C,Li X,Bingyin S

更新日期：2013-01-01 00:00:00

abstract：:Many studies have assessed the association between eNOS-4b/a polymorphism and the risk of diabetic retinopathy (DR) among type 2 diabetic subjects. However, the results are inconsistent. In order to derive a more precise estimation of the association, a meta-analysis was conducted. Fifteen studies with 3, 183 cases an...

journal_title：Journal of diabetes research

authors： Ma ZJ,Chen R,Ren HZ,Guo X,Guo J,Chen LM

更新日期：2014-01-01 00:00:00

abstract：:The rapid rise of type II diabetes mellitus and its accompanying vascular complications call for novel approaches in unravelling its pathophysiological mechanisms and designing new treatment modalities. Noncoding RNAs represent a class of previously unknown molecular modulators of this disease. The most important feat...

journal_title：Journal of diabetes research

authors： Eken SM,Jin H,Chernogubova E,Maegdefessel L

更新日期：2013-01-01 00:00:00

abstract：Objective:The aim of the study was to investigate the independent and combined effects of the cortisol-to-cortisone ratio (F/E) and 11-deoxycortisol on prediabetes and type 2 diabetes mellitus (T2DM) among different genders. Methods:A case-control study was performed including 2676 participants from the Henan Rural Co...

journal_title：Journal of diabetes research

authors： Liu X,Jiang J,Liu X,Luo Z,Wang Y,Dong X,Wei D,Huo W,Yu S,Li L,Jin S,Wang C,Mao Z

更新日期：2019-06-02 00:00:00

abstract：:To observe the changes of lung injury when diabetic rats were treated with low concentration of ethanol (EtOH) and analyze the related mechanisms, male Sprague-Dawley (SD) rats were divided into control, diabetic (DM), and EtOH+DM groups. Diabetic rat was mimicked by injection of streptozotocin intraperitoneally. Fast...

journal_title：Journal of diabetes research

authors： Hu JF,Zhang GJ,Wang L,Kang PF,Li J,Wang HJ,Gao Q,Chen YQ

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Experimental and clinical studies suggest a possible association between vitamin D deficiency and both diabetic retinopathy and maculopathy. METHODS:We have performed a cross-sectional study in adults with types 1 and 2 diabetes mellitus. The relationship between the presence and severity of diabetic retino...

journal_title：Journal of diabetes research

authors： Alam U,Amjad Y,Chan AW,Asghar O,Petropoulos IN,Malik RA

更新日期：2016-01-01 00:00:00

abstract：:Diabetic retinopathy (DR) is a severe sight-threatening complication of diabetes mellitus. Retinal laser photocoagulation, antivascular endothelial growth factors, steroid therapy, and pars plana vitrectomy are now used extensively to treat advanced stages of diabetic retinopathy. Currently, diagnostic devices like ul...

journal_title：Journal of diabetes research

authors： Park YG,Roh YJ

更新日期：2016-01-01 00:00:00

abstract：Background:Chronic overnutrition leads to cardiac dysfunction and insulin (INS) resistance. Dipeptidyl peptidase-4 (DPP-4) improves glucose metabolism and insulin sensitivity in both human and animal models. In this study, we explored whether DPP-4 inhibitor sitagliptin (SIT) is involved in the protection of cardiac fu...

journal_title：Journal of diabetes research

authors： Qiao S,Mao G,Li H,Ma Z,Hong L,Zhang H,Wang C,An J

更新日期：2018-07-17 00:00:00

abstract：:South Asians have high prevalence of diabetes, cardiovascular risk, and physical inactivity. Reasons for physical inactivity have not been explored among Asians living within their endogenous environments. During phase 1 of the study, we assessed the physical activity (PA) of the population using a quantitative, descr...

journal_title：Journal of diabetes research

authors： Medagama A,Galgomuwa M

更新日期：2018-03-06 00:00:00

abstract：Purpose:Nontraditional cardiovascular risk factors as apolipoprotein A (ApoA), apolipoprotein B (ApoB), and the proprotein convertase subtilisin/kexin type 9 (PCSK9) increase the prevalence of cardiovascular mortality in chronic kidney disease (CKD) or in end-stage renal disease (ESRD) through quantitative alterations....

journal_title：Journal of diabetes research

authors： Vlad CE,Foia L,Popescu R,Ivanov I,Luca MC,Delianu C,Toma V,Statescu C,Rezus C,Florea L

更新日期：2019-12-14 00:00:00

abstract：:Insulin resistance plays a key role in the development of type 2 diabetes. It arises from a combination of genetic predisposition and environmental and lifestyle factors including lack of physical exercise and poor nutrition habits. The increased risk of type 2 diabetes is molecularly based on defects in insulin signa...

journal_title：Journal of diabetes research

authors： Röhling M,Herder C,Stemper T,Müssig K

更新日期：2016-01-01 00:00:00

abstract：Aim:To evaluate the effect of an inhibitor of sodium-glucose cotransporter 2 (SGLT-2 inhibitor, dapagliflozin) on glycemic variability in type 2 diabetes mellitus (T2D) under insulin glargine combined with oral hypoglycemic drugs, using a continuous glucose monitoring system (CGMS). Methods:This prospective, self-cont...

journal_title：Journal of diabetes research

authors： Luo M,Kong X,Wang H,Zhai X,Cai T,Ding B,Hu Y,Jing T,Su X,Li H,Ma J

更新日期：2020-11-24 00:00:00

abstract：:Type 1 diabetes mellitus (T1DM) is a long-term and chronic autoimmune disorder, in which the immune system attacks the pancreatic β-cells. Both adaptive and innate immune systems are involved in T1DM development. Both B-cells and T-cells, including CD4 + and CD8 ...

journal_title：Journal of diabetes research

authors： Sun L,Xi S,He G,Li Z,Gang X,Sun C,Guo W,Wang G

更新日期：2020-07-30 00:00:00

abstract：:The association between diabetes mellitus (DM) and high mortality linked to cardiovascular disease (CVD) is a major concern worldwide. Clinical and preclinical studies have demonstrated a variety of diastolic and systolic dysfunctions in patients with type 2 diabetes mellitus (T2DM) with the severity of abnormalities ...

journal_title：Journal of diabetes research

authors： Al Kury L,Smail M,Qureshi MA,Sydorenko V,Shmygol A,Oz M,Singh J,Howarth FC

更新日期：2018-04-10 00:00:00

abstract：:We investigated the association of serum homocysteine levels and vitamin status with type 2 diabetic retinopathy. This study included 65 patients with and 75 patients without diabetic retinopathy. Patients with diabetic retinopathy had significantly higher serum homocysteine levels (P < 0.001), higher prevalence of hy...

journal_title：Journal of diabetes research

authors： Fotiou P,Raptis A,Apergis G,Dimitriadis G,Vergados I,Theodossiadis P

更新日期：2014-01-01 00:00:00

abstract：:The neurodegenerative and inflammatory environment that is prevalent in the diabetic eye is a key player in the development and progression of diabetic retinopathy. The adenosinergic system is widely regarded as a significant modulator of neurotransmission and the inflammatory response, through the actions of the four...

journal_title：Journal of diabetes research

authors： Vindeirinho J,Santiago AR,Cavadas C,Ambrósio AF,Santos PF

更新日期：2016-01-01 00:00:00

abstract：:The purpose of this study was to investigate the effects of sodium-glucose cotransporter 2 inhibitors (SGLT2i) on the progression of diabetic retinopathy (DR) in patients with type 2 diabetes. The medical records of 21 type 2 diabetic patients who used a SGLT2i and 71 patients with sulfonylurea (control) were reviewed...

journal_title：Journal of diabetes research

authors： Cho EH,Park SJ,Han S,Song JH,Lee K,Chung YR

更新日期：2018-12-05 00:00:00

abstract：OBJECTIVE:To compare the serum concentration of IL-6, IL-10, TNF, IL-8, resistin, and adiponectin in type 1 diabetic patients with and without metabolic syndrome and to determine the cut-off point of the estimated glucose disposal rate that accurately differentiated these groups. DESIGN:We conducted a cross-sectional ...

journal_title：Journal of diabetes research

authors： Ferreira-Hermosillo A,Molina-Ayala M,Ramírez-Rentería C,Vargas G,Gonzalez B,Isibasi A,Archundia-Riveros I,Mendoza V

更新日期：2015-01-01 00:00:00

abstract：Background:Diabetic retinopathy (DR) is a severe complication of diabetes mellitus. DR is considered as a neurovascular disease. Retinal ganglion cell (RGC) loss plays an important role in the vision function disorder of diabetic patients. Histone deacetylase3 (HDAC3) is closely related to injury repair and nerve regen...

journal_title：Journal of diabetes research

authors： Fu Y,Wang Y,Gao X,Li H,Yuan Y

更新日期：2020-03-01 00:00:00

abstract：:Aims. To examine whether fibrinogen levels are a valuable biomarker for assessing disease severity and monitoring disease progression in patients with diabetic foot ulcer (DFU). Methods. A retrospective study was designed to examine the utility of fibrinogen in estimating disease severity in patients with DFU admitted...

journal_title：Journal of diabetes research

authors： Li XH,Guan LY,Lin HY,Wang SH,Cao YQ,Jiang XY,Wang YB

更新日期：2016-01-01 00:00:00

abstract：:Diabetes mellitus (DM) is a major worldwide health problem and its prevalence has been rapidly increasing in the last century. It is caused by defects in insulin secretion or insulin action or both, leading to hyperglycemia. Of the various types of DM, type 2 occurs most frequently. Multiple genes and their interactio...

journal_title：Journal of diabetes research

authors： Haghvirdizadeh P,Mohamed Z,Abdullah NA,Haghvirdizadeh P,Haerian MS,Haerian BS

更新日期：2015-01-01 00:00:00

abstract：Background:The risk factors for acute kidney injury (AKI) development in patients with diabetes hospitalized for COVID-19 have not been fully studied yet. In this study, we aimed to estimate the rate of AKI among the hospitalized population with COVID-19 and to identify the risk factors associated with AKI among patien...

journal_title：Journal of diabetes research

authors： Khalili S,Sabaghian T,Sedaghat M,Soroureddin Z,Askari E,Khalili N

更新日期：2021-01-06 00:00:00

abstract：Background:Gestational diabetes mellitus (GDM) contributes to adverse pregnancy and birth outcomes. In recent decades, extensive research has been devoted to the early prediction of GDM by various methods. Machine learning methods are flexible prediction algorithms with potential advantages over conventional regression...

journal_title：Journal of diabetes research

authors： Ye Y,Xiong Y,Zhou Q,Wu J,Li X,Xiao X

更新日期：2020-06-12 00:00:00

abstract：:Fear of falling (FoF) is known to affect the physical activities and quality of life of older adults with type 2 diabetes mellitus (DM). Many complications of DM, especially ones distressing lower extremity (LE), could lead to increased fall risk and FoF. This study aimed to explore the relationship between FoF, LE mu...

journal_title：Journal of diabetes research

authors： Vongsirinavarat M,Mathiyakom W,Kraiwong R,Hiengkaew V

更新日期：2020-06-03 00:00:00

abstract：:Clopidogrel (INN), an oral antiplatelet drug, has been revealed to have a number of biological properties, for instance, anti-inflammation and antioxidation. Oxidative stress plays an imperative role in inflammation, diabetes mellitus, atherosclerosis, and cancer. In the present study, human aortic endothelial cells (...

journal_title：Journal of diabetes research

authors： Yang H,Zhao P,Tian S

更新日期：2016-01-01 00:00:00