The Effect of Dantonic Pill on β -Catenin Expression in a Rat Model of Streptozotocin-Induced Early Stage of Diabetic Nephropathy.

abstract：:It is understood that intrauterine hyperglycemia increases the risk of obesity and diabetes in offspring of consecutive generations but its mechanisms remain obscure. This study is aimed at establishing an intrauterine hyperglycemia rat model to investigate the growth and glycolipid metabolic characteristics in transg...

journal_title：Journal of diabetes research

authors： Zhang W,Su R,Feng H,Lin L,Wang C,Yang H

更新日期：2019-09-12 00:00:00

abstract：:Aims. To examine whether fibrinogen levels are a valuable biomarker for assessing disease severity and monitoring disease progression in patients with diabetic foot ulcer (DFU). Methods. A retrospective study was designed to examine the utility of fibrinogen in estimating disease severity in patients with DFU admitted...

journal_title：Journal of diabetes research

authors： Li XH,Guan LY,Lin HY,Wang SH,Cao YQ,Jiang XY,Wang YB

更新日期：2016-01-01 00:00:00

abstract：Background and Aims:Diabetic foot ulcers (DFUs) are linked to amputations and premature deaths. Negative pressure wound therapy (NPWT) has been used for DFUs. The mechanism of NPWT's action may be associated with its influence on circulating molecules. We assessed NPWT's effect on the plasma levels of angiopoietin-2 (A...

journal_title：Journal of diabetes research

authors： Hohendorff J,Drozdz A,Borys S,Ludwig-Slomczynska AH,Kiec-Wilk B,Stepien EL,Malecki MT

更新日期：2019-10-28 00:00:00

abstract：:Most patients with type 2 diabetes (T2D) have suboptimal adherence to recommended diet, physical activity, and/or medication. Current approaches to improve health behaviors in T2D have been variably effective, and successful interventions are often complex and intensive. It is therefore vital to develop interventions ...

journal_title：Journal of diabetes research

authors： Huffman JC,DuBois CM,Millstein RA,Celano CM,Wexler D

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To compare the serum concentration of IL-6, IL-10, TNF, IL-8, resistin, and adiponectin in type 1 diabetic patients with and without metabolic syndrome and to determine the cut-off point of the estimated glucose disposal rate that accurately differentiated these groups. DESIGN:We conducted a cross-sectional ...

journal_title：Journal of diabetes research

authors： Ferreira-Hermosillo A,Molina-Ayala M,Ramírez-Rentería C,Vargas G,Gonzalez B,Isibasi A,Archundia-Riveros I,Mendoza V

更新日期：2015-01-01 00:00:00

abstract：:In bioartificial pancreases (BP), the number of islets needed to restore normoglycaemia in the diabetic patient is critical. However, the confinement of a high quantity of islets in a limited space may impact islet survival, particularly in regard to the low oxygen partial pressure (PO2) in such environments. The aim ...

journal_title：Journal of diabetes research

authors： Rodriguez-Brotons A,Bietiger W,Peronet C,Magisson J,Sookhareea C,Langlois A,Mura C,Jeandidier N,Pinget M,Sigrist S,Maillard E

更新日期：2016-01-01 00:00:00

abstract：:Aims. Dipeptidyl-peptidase IV inhibitors (DPP-4i) are among the most popular oral antidiabetic agents. However, the effects of DPP-4i on diabetic nephropathy are not well-established. The aim of this study was to determine the renoprotective effects of DPP-4i, using albuminuria and glomerular filtration rate (GFR) as ...

journal_title：Journal of diabetes research

authors： Kim YG,Byun J,Yoon D,Jeon JY,Han SJ,Kim DJ,Lee KW,Park RW,Kim HJ

更新日期：2016-01-01 00:00:00

abstract：AIMS:Type 1 diabetes (T1D) is often associated with early microvascular complications. Previous studies demonstrated that increased systolic (SAP) and diastolic arterial blood pressures (DAP) are linked to microvascular morbidity in T1D. The aim of the study was to investigate the predictive role of neutrophil gelatina...

journal_title：Journal of diabetes research

authors： Papadopoulou-Marketou N,Margeli A,Papassotiriou I,Chrousos GP,Kanaka-Gantenbein C,Wahlberg J

更新日期：2017-01-01 00:00:00

abstract：Objectives:This study is aimed at gaining insights on the changing prevalence, economic burden, and catastrophic costs of diabetes in rural southwest China. Materials and Methods:Data were collected from two cross-sectional health interviews and examination surveys among individuals aged ≥ 35 years in rural Yunnan Pro...

journal_title：Journal of diabetes research

authors： Li HF,Cai L,Golden AR

更新日期：2019-08-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2018/6239158.]. ...

journal_title：Journal of diabetes research

authors： Abdella NA,Mojiminiyi OA

更新日期：2018-10-22 00:00:00

abstract：:Methylglyoxal (MG) is a highly reactive glucose metabolic intermediate and a major precursor of advanced glycation end products. MG level is elevated in hyperglycemic disorders such as diabetes mellitus. Substantial evidence has shown that MG is involved in the pathogenesis of diabetes and diabetic complications. We i...

journal_title：Journal of diabetes research

authors： Bo J,Xie S,Guo Y,Zhang C,Guan Y,Li C,Lu J,Meng QH

更新日期：2016-01-01 00:00:00

abstract：Aim:To evaluate the effect of an inhibitor of sodium-glucose cotransporter 2 (SGLT-2 inhibitor, dapagliflozin) on glycemic variability in type 2 diabetes mellitus (T2D) under insulin glargine combined with oral hypoglycemic drugs, using a continuous glucose monitoring system (CGMS). Methods:This prospective, self-cont...

journal_title：Journal of diabetes research

authors： Luo M,Kong X,Wang H,Zhai X,Cai T,Ding B,Hu Y,Jing T,Su X,Li H,Ma J

更新日期：2020-11-24 00:00:00

abstract：:Type 2 diabetes mellitus is prevalent especially in Gulf countries and poses serious long-term risks to patients. A multifaceted treatment approach can include nutritional supplements with antioxidant properties such as 5-aminolevulinic acid (5-ALA) with sodium ferrous citrate (SFC). This prospective, randomized, sing...

journal_title：Journal of diabetes research

authors： Al-Saber F,Aldosari W,Alselaiti M,Khalfan H,Kaladari A,Khan G,Harb G,Rehani R,Kudo S,Koda A,Tanaka T,Nakajima M,Darwish A

更新日期：2016-01-01 00:00:00

abstract：Objective:Diabetic kidney disease (DKD) is the most common cause of end-stage renal disease (ESRD). Even after strict control of obesity, hyperglycemia, and hypertension, some patients still progress rapidly. Previous studies suggested diabetic dyslipidemia might be one of the factors responsible for this high residual...

journal_title：Journal of diabetes research

authors： Wang C,Wang L,Liang K,Yan F,Hou X,Liu F,Chen L

更新日期：2020-09-28 00:00:00

abstract：:Objectives. To compare the prevalence of diabetic peripheral neuropathy (DPN) and that of cardiac autonomic neuropathy (CAN) between South Asians and White Caucasians with type 2 diabetes and to explore reasons for observed differences. Methods. A cross-sectional study of casually selected South Asian and White Caucas...

journal_title：Journal of diabetes research

authors： Tahrani AA,Altaf QA,Piya MK,Barnett AH

更新日期：2017-01-01 00:00:00

abstract：:To study the relationship between glycosylated hemoglobin (HgbA1c) and myocardial perfusion in type 2 diabetes mellitus (T2DM) patients, we prospectively enrolled 24 patients with known or suspected coronary artery disease (CAD) who underwent adenosine stress by real-time myocardial perfusion echocardiography (RTMPE)....

journal_title：Journal of diabetes research

authors： Huang R,Abdelmoneim SS,Nhola LF,Mulvagh SL

更新日期：2014-01-01 00:00:00

abstract：Background:Diabetic retinopathy (DR) is a severe complication of diabetes mellitus. DR is considered as a neurovascular disease. Retinal ganglion cell (RGC) loss plays an important role in the vision function disorder of diabetic patients. Histone deacetylase3 (HDAC3) is closely related to injury repair and nerve regen...

journal_title：Journal of diabetes research

authors： Fu Y,Wang Y,Gao X,Li H,Yuan Y

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:Glucagon-like peptide-1 (GLP-1) analogues (e.g., exenatide) increase insulin secretion in diabetes but less is known about their effects on glucose production or insulin-stimulated glucose uptake in peripheral tissues. METHODS:Four groups of Sprague-Dawley rats were studied: nondiabetic (control, C); nondiab...

journal_title：Journal of diabetes research

authors： Wu H,Sui C,Xu H,Xia F,Zhai H,Zhang H,Weng P,Han B,Du S,Lu Y

更新日期：2014-01-01 00:00:00

abstract：:Globally, noncommunicable chronic diseases such as Type-2 Diabetes Mellitus (T2DM) and Coronary Artery Disease (CAD) are posing a major threat to the world. T2DM is known to potentiate CAD which had led to the coining of a new clinical entity named diabetic CAD (DM-CAD), leading to excessive morbidity and mortality. T...

journal_title：Journal of diabetes research

authors： Aravindhan V,Madhumitha H

更新日期：2016-01-01 00:00:00

abstract：:The rapid rise of type II diabetes mellitus and its accompanying vascular complications call for novel approaches in unravelling its pathophysiological mechanisms and designing new treatment modalities. Noncoding RNAs represent a class of previously unknown molecular modulators of this disease. The most important feat...

journal_title：Journal of diabetes research

authors： Eken SM,Jin H,Chernogubova E,Maegdefessel L

更新日期：2013-01-01 00:00:00

abstract：:According to the American Diabetes Association (ADA), the side effects of diabetes mellitus have recently increased the global health expenditure each year. Of these, the early diagnostic can contribute to the decrease on renal, cardiovascular, and nervous systems complications. However, the diagnostic criteria, which...

journal_title：Journal of diabetes research

authors： Arroyo-Carmona RE,López-Serrano AL,Albarado-Ibañez A,Mendoza-Lucero FM,Medel-Cajica D,López-Mayorga RM,Torres-Jácome J

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:Puerarin is a natural flavonoid isolated from the TCM lobed kudzuvine root. This study investigated the effect and mechanisms of puerarin on diabetic aorta in rats. METHODS:Streptozotocin- (STZ-) induced diabetic rats were administered with puerarin for 3 weeks. Levels of serum insulin (INS), PGE2, endotheli...

journal_title：Journal of diabetes research

authors： Li W,Zhao W,Wu Q,Lu Y,Shi J,Chen X

更新日期：2016-01-01 00:00:00

abstract：:Forefoot load (FL) contributes to callus formation, which is one of the pathways to diabetic foot ulcers (DFU). In this study, we hypothesized that excessive FL, which cannot be detected by plantar load measurements within laboratory settings, occurs in daily walks. To demonstrate this, we created a FL estimation algo...

journal_title：Journal of diabetes research

authors： Watanabe A,Noguchi H,Oe M,Sanada H,Mori T

更新日期：2017-01-01 00:00:00

abstract：Objective:To evaluate (1) the longitudinal relationship between parental well-being and glycemic control in youth with type 1 diabetes and (2) if youth's problem behavior, diabetes parenting behavior, and parental diabetes-distress influence this relationship. Research Design and Methods:Parents of youth 8-15 yrs (at ...

journal_title：Journal of diabetes research

authors： Eilander MMA,Snoek FJ,Rotteveel J,Aanstoot HJ,Bakker-van Waarde WM,Houdijk ECAM,Nuboer R,Winterdijk P,de Wit M

更新日期：2017-01-01 00:00:00

abstract：:Native Hawaiians and other Pacific Islanders (NH/PI; e.g., Samoan and Chuukese) have higher type 2 diabetes prevalence compared to other groups in Hawai'i. Partners in Care (PIC), a culturally tailored, community-based, diabetes self-management education intervention (DSME), is effective at improving participants' gly...

journal_title：Journal of diabetes research

authors： Ing CT,Zhang G,Dillard A,Yoshimura SR,Hughes C,Palakiko DM,Kehauoha BP,Sinclair KA,Kaholokula JK

更新日期：2016-01-01 00:00:00

abstract：:Diabetes mellitus (DM) is a major worldwide health problem and its prevalence has been rapidly increasing in the last century. It is caused by defects in insulin secretion or insulin action or both, leading to hyperglycemia. Of the various types of DM, type 2 occurs most frequently. Multiple genes and their interactio...

journal_title：Journal of diabetes research

authors： Haghvirdizadeh P,Mohamed Z,Abdullah NA,Haghvirdizadeh P,Haerian MS,Haerian BS

更新日期：2015-01-01 00:00:00

abstract：:Insulin resistance plays a key role in the development of type 2 diabetes. It arises from a combination of genetic predisposition and environmental and lifestyle factors including lack of physical exercise and poor nutrition habits. The increased risk of type 2 diabetes is molecularly based on defects in insulin signa...

journal_title：Journal of diabetes research

authors： Röhling M,Herder C,Stemper T,Müssig K

更新日期：2016-01-01 00:00:00

abstract：:The aim of this study is to evaluate the effects of regular moderate exercise training initiated previously or after induction of diabetes mellitus on renal oxidative stress and inflammation in STZ-induced diabetic female rats. For this purpose, Wistar rats were divided into five groups: sedentary control (SC), traine...

journal_title：Journal of diabetes research

authors： Amaral LSB,Souza CS,Volpini RA,Shimizu MHM,de Bragança AC,Canale D,Seguro AC,Coimbra TM,de Magalhães ACM,Soares TJ

更新日期：2018-03-29 00:00:00

abstract：AIM:The aim of this study was to evaluate the incidence of diabetic ketoacidosis in children and adolescents with newly diagnosed type 1 diabetes in 2006-2007 and 2013-2014. METHOD:The study group consisted of 426 children aged 0-18 years with type 1 diabetes onset admitted to our hospital in 2006-2007 (group A) and 2...

journal_title：Journal of diabetes research

authors： Szypowska A,Ramotowska A,Grzechnik-Gryziak M,Szypowski W,Pasierb A,Piechowiak K

更新日期：2016-01-01 00:00:00

abstract：:Background. The aim of this study was to validate the impact of type 2 diabetes (T2D) on the platelet reactivity in patients with acute ST elevation myocardial infarction (STEMI) treated with adenosine diphosphate (ADP) receptor blockers. Methods. A pilot prospective study was performed. Totally 67 patients were enrol...

journal_title：Journal of diabetes research

authors： Samoš M,Fedor M,Kovář F,Galajda P,Bolek T,Stančiaková L,Fedorová J,Staško J,Kubisz P,Mokáň M

更新日期：2016-01-01 00:00:00