Abstract:
:Cardiac surgery with cardiopulmonary bypass (CPB) is frequently associated with a complex array of post-operative clinical abnormalities, including low-output syndrome and pulmonary dysfunction. It has been reported that oxygen free radicals are one of the important factors causing reperfusion injury. To determine whether oxygen free radicals are produced during cardiac surgery, we studied nine patients anesthetized with high doses of fentanyl. Lipid peroxide (LPO) and leukotriene B4 (LTB4) levels increased significantly from 60 min after aortic ligation to 180 min after reperfusion (aortic declamping), compared with the levels before surgery, while superoxide dismutase (SOD) was not affected markedly. Creatine kinase (CK), CK muscle-brain (CK-MB), and neutrophils increased from 60 min after aortic declamping. Correlations were not observed between LPO and CK nor between LPO and CK-MB. These results suggest that free radicals are generated during cardiac surgery with cardiopulmonary bypass (CPB), but it is unclear whether free radicals cause tissue injury after cardiac surgery with CPB.
journal_name
J Anesthjournal_title
Journal of anesthesiaauthors
Kawamura T,Sakurada H,Okada K,Wakusawa R,Ito Hdoi
10.1007/BF02483345subject
Has Abstractpub_date
1996-06-01 00:00:00pages
111-114issue
2eissn
0913-8668issn
1438-8359pii
10.1007/BF02483345journal_volume
10pub_type
杂志文章abstract:PURPOSE:The newly introduced erector spinae plane block (ESPB) has given anesthesiologists an alternative regional anesthetic technique for thoracic analgesia. Although ESPB and retrolaminar block (RLB) have similar puncture sites, no clinical study comparing ESPB and RLB has been reported. The aim of this study was to...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-020-02855-y
更新日期:2021-02-01 00:00:00
abstract::Levobupivacaine has been developed as a safer alternative to bupivacaine because of its reduced systemic toxicity. However, the effect of directly delivering levobupivacaine into tracheal smooth muscle has not been adequately explored. We performed this study to determine the in vitro effects of levobupivacaine on iso...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-015-2026-8
更新日期:2015-10-01 00:00:00
abstract:PURPOSE:In many countries, patients are generally allowed to have clear fluids until 2-3 h before surgery. In Japan, long preoperative fasting is still common practice. To shorten the preoperative fasting period in Japan, we tested the safety and efficacy of oral rehydration therapy until 2 h before surgery. METHODS:T...
journal_title:Journal of anesthesia
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00540-011-1261-x
更新日期:2012-02-01 00:00:00
abstract:PURPOSE:This study aimed to evaluate whether the three ryanodine receptor type 1 (RYR1) variants (p.Ser2345Thr, p.Ser2345Arg, and p.Lys3367Arg) which we identified in Japanese malignant hyperthermia (MH) patients with a clinical grading scale rank of 6 were causative for MH. METHODS:We prepared human embryonic kidney ...
journal_title:Journal of anesthesia
pub_type: 杂志文章,收录出版
doi:10.1007/s00540-020-02803-w
更新日期:2020-10-01 00:00:00
abstract::Neuropathic pain has a substantial effect on quality of life (QOL). The Japanese Society of Pain Clinicians (JSPC) has developed clinical guidelines of pharmacotherapy for neuropathic pain. These guidelines offer clarity on recommendations based on both the most recent scientific evidence and expert opinions. Understa...
journal_title:Journal of anesthesia
pub_type: 杂志文章,实务指引
doi:10.1007/s00540-018-2501-0
更新日期:2018-06-01 00:00:00
abstract::Brachial plexus block is commonly used for upper limb surgery. Although the procedure is safe, it may be associated with some life-threatening complications. We performed right-sided supraclavicular brachial plexus block for below-elbow amputation in a 45-year-old female. At completion of the block the patient develop...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-010-1076-1
更新日期:2011-04-01 00:00:00
abstract::Adenosine triphosphate as well as sodium nitroprusside has been used for hypotensive anesthesia. The purpose of this study was to examine the possibility that two hypotensive drugs may exert different effects on venous capacitance during controlled hypotension. In rats anesthetized with ketamine, mean arterial pressur...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054070010143
更新日期:1987-09-01 00:00:00
abstract::Beta-adrenergic blockers (β-blockers) are clearly indicated for the long-term treatment of patients with systolic heart failure and post-acute myocardial infarction. Early small-scale studies reported their potential benefits for perioperative use; subsequent randomized controlled trials, however, failed to reproduce ...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
doi:10.1007/s00540-019-02691-9
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:Multimodal analgesia increases the chance of successful discharge and pain control after surgery, and pregabalin is being promoted as an effective analgesic, based on placebo-controlled studies. We investigated whether adding pregabalin improved pain control and reduced opioid requests when it was added to a mu...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-012-1447-x
更新日期:2012-12-01 00:00:00
abstract::The purpose of this multi-center study was to evaluate the efficacy and safety of prostaglandin E1 (PGE1) administration in achieving deliberate hypotension and in treating intraoperative hypertension for patients with a history of hypertension and ischemic heart disease. PGE1 (0.08 microg.kg(-1).min(-1)) decreased sy...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054030070173
更新日期:1993-04-01 00:00:00
abstract::Cardiopulmonary resuscitation (CPR) in the lateral position during noncardiac surgery has been described in only a few reports in the past. Here, we report a case of cardiac arrest in a 61-year-old man undergoing microvascular decompression surgery for trigeminal neuralgia in the left lateral decubitus position. Durin...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-010-0911-8
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:Postanesthetic shivering can be triggered by surgical stress and several aspects of anesthetic management and is frequently preceded by a decrease in peripheral blood flow due to thermoregulatory vasoconstriction. As perfusion index correlates with peripheral blood flow, we examined whether perioperative per...
journal_title:Journal of anesthesia
pub_type: 临床试验,杂志文章
doi:10.1007/s00540-013-1658-9
更新日期:2014-02-01 00:00:00
abstract::We tested hypertonic saline solution (HS) to determine its effectiveness in surgical procedures for prostatic hypertrophy. We randomly selected 40 patients undergoing elective transurethral resection of the prostate for either infusion of HS (3% NaCl) at 4ml·kg(-1)·min(-1) (HS group) or lactated Ringer's solution (LR)...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02471385
更新日期:1996-09-01 00:00:00
abstract::We report on the anesthetic management of a 69-year-old female Jehovah's Witness undergoing cardiopulmonary bypass to replace the ascending aorta; the patient refused transfusion of stored autologous or allogeneic blood products for religious reasons. The strategy involved preoperative hematopoiesis with recombinant h...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-009-0764-1
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:We previously confirmed the effectiveness of dexmedetomidine (DEX) for stabilizing hemodynamics as well as sparing anesthetics during anesthetic induction in patients undergoing cardiac surgery (Kunisawa et al. in J Clin Anesth 21:194-199, 1). In this study, we investigated whether these effects of DEX continue...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-011-1215-3
更新日期:2011-12-01 00:00:00
abstract::Although anaphylactoid reactions to local anesthetics are well known, a radioallergosorbent test (RAST) to detect specific drug reagin (IgE) anti-body has not been developed. We established RAST for local anesthetics by using carboxylic acid derivatives of lidocaine, procaine and methylparaben. Serum samples were take...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054090030074
更新日期:1989-03-01 00:00:00
abstract:PURPOSE:Although an α-adrenoceptor has been suggested to be involved in the mechanism of asthma, the effect of α1-agonist on the airway is still unclear. In this study we evaluated the effect of phenylephrine on the airway with a direct visualization method using a superfine fiberoptic bronchoscope (SFB). METHODS:Seve...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02480091
更新日期:1998-09-01 00:00:00
abstract:BACKGROUND:Rocuronium (Rb) is ideal for continuous infusion but has a widely variable duration of action. We investigated the distribution of Rb infusion in a steady state of optimal muscle relaxation and the relationship between the measured and predicted blood Rb concentrations in laparoscopic surgery. METHODS:Seven...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-014-1879-6
更新日期:2015-02-01 00:00:00
abstract:PURPOSE:We aimed to evaluate postoperative analgesia of morphine, or clonidine, or morphine plus clonidine, added to caudal bupivacaine in children undergoing infra-umbilical urological and genital procedures. METHODS:Eighty patients aged 1-10 years were prospectively enrolled. After the induction of general anesthesi...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-011-1297-y
更新日期:2012-04-01 00:00:00
abstract:PURPOSE:In a previous study using the tail-flick test, we found that intracerebroventricular administration of D-serine, an endogenous co-agonist at the glycine sites of N-methyl-D-aspartate (NMDA) receptors, elicited an antinociceptive effect on thermal nociception. The purpose of the present study was to evaluate the...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1708-3
更新日期:2014-04-01 00:00:00
abstract::A 75-year-old female patient underwent right vitrectomy under total intravenous anesthesia with propofol, ketamine and fentanyl. During the surgery sudden severe bradycardia (heart rate, 33 beats per min), without hypotension, occurred, which was relatively atropine-insensitive. This event was accompanied by a marked ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-008-0632-4
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Cardiac surgery and sternotomy are procedures accompanied by substantial postoperative pain which is challenging to treat. In general, intravenous (IV) opioids are used in the immediate postoperative phase, followed by oral opioids. Oral opioids are easier to use and generally less expensive. Our goal was th...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-013-1770-x
更新日期:2014-08-01 00:00:00
abstract::A 24-year-old man underwent surgery for a fractured left clavicle and received an interscalene brachial plexus block for intraoperative and postoperative analgesia. After injection of 40 ml 0.5% ropivacaine and confirmation of analgesia, general anesthesia was induced and maintained with propofol. Although the operati...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-011-1125-4
更新日期:2011-06-01 00:00:00
abstract::Cardiac surgery-associated acute kidney injury (AKI) is a major health problem that is extremely common and has a significant effect on cardiac surgical outcomes. AKI occurs in nearly 30 % of patients undergoing cardiac surgery, with about 1-2 % of these ultimately requiring dialysis. The development of AKI predicts a...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
doi:10.1007/s00540-012-1523-2
更新日期:2013-06-01 00:00:00
abstract:PURPOSE:Ultrasound (US)-guided continuous interscalene brachial plexus block (CBPB) is known to provide effective pain relief for arthroscopic rotator cuff repair. This study was conducted to compare analgesic efficacy and forearm muscle tone of the basal infusion rate and bolus dose of 0.2 % ropivacaine for US-guided ...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-013-1681-x
更新日期:2014-02-01 00:00:00
abstract:PURPOSE:Facemask ventilation during the induction of general anesthesia in paediatric patients remains a challenge as it may result in hypoxic conditions and gastric insufflation with subsequent regurgitation and aspiration. So far, it is unclear if pressure-controlled or manual facemask ventilation is preferable in ch...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-018-2580-y
更新日期:2019-02-01 00:00:00
abstract::Tarsal tunnel syndrome (TTS) is a compression neuropathy that results from entrapment of the posterior tibial nerve or its branches. TTS may be treated either by conservative measures, including physical therapy, medications, and steroid injections, or by surgical decompression. Despite a variety of treatments, a few ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-014-1831-9
更新日期:2014-12-01 00:00:00
abstract::The impact of postoperative atrial fibrillation (PAF) on patient outcomes has prompted intense investigation into the optimal methods for prevention and treatment of this complication. In the prevention of PAF, β-blockers and amiodarone are particularly effective and are recommended by guidelines. However, their use r...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
doi:10.1007/s00540-012-1330-9
更新日期:2012-06-01 00:00:00
abstract::To avoid the risk of R-on-T incident and the unnecessary decrease of cardiac output, we devised an algorithm consisting of six steps for choosing the most appropriate intraoperative pacemaker (PM) mode, which is modified from Heart Rhythm Society and the American Society of Anesthesiologists expert consensus statement...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-020-02878-5
更新日期:2021-02-01 00:00:00
abstract::Muscle relaxation induced by neuromuscular blocking agents (NMBAs) is necessary for tracheal intubation and immobilization during surgery. Although acetylcholinesterase inhibitors have been successfully used as antagonists for NMBAs, they have their limitations; their effects are transient and ineffective against prof...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-020-02836-1
更新日期:2020-10-01 00:00:00