Abstract:
:Neuropathic pain has a substantial effect on quality of life (QOL). The Japanese Society of Pain Clinicians (JSPC) has developed clinical guidelines of pharmacotherapy for neuropathic pain. These guidelines offer clarity on recommendations based on both the most recent scientific evidence and expert opinions. Understanding the concept, disease entity, and burden of neuropathic pain, as well as its screening and diagnosis are important steps before starting pharmacotherapy. As well as other guidelines, the guidelines propose several lines of pharmacotherapies in a step-wise manner. To name a few different points, our guidelines propose an extract from inflamed cutaneous tissue of rabbits inoculated with vaccinia virus, which has been found to be effective for post-herpetic neuralgia in Japan, as one of the second-line drugs. When prescribing opioid analgesics, proposed as the third-line drugs, for neuropathic pain, the guidelines recommend physicians continue evaluations on either abuse or addiction. The guidelines do not recommend concomitant use of nonsteroidal anti-inflammatory drugs and acetaminophen because of lack of clinical evidence of their efficacy. If patients do not respond well to pharmacotherapy, which is prescribed in a step-wise manner, other treatment strategies should be considered to improve patients' activities of daily living and QOL.
journal_name
J Anesthjournal_title
Journal of anesthesiaauthors
Sumitani M,Sakai T,Matsuda Y,Abe H,Yamaguchi S,Hosokawa T,Fukui Sdoi
10.1007/s00540-018-2501-0subject
Has Abstractpub_date
2018-06-01 00:00:00pages
463-478issue
3eissn
0913-8668issn
1438-8359pii
10.1007/s00540-018-2501-0journal_volume
32pub_type
杂志文章,实务指引abstract::To evaluate the effects of subanesthetic enflurane and sevoflurane on the sympathetic nervous system (SNS) and the parasympathetic nervous system (PNS), the blood level of norepinephrine (NE) and fluctuations in the R-R intervals were measured on electrocardiogram in humans given either 0.5 MAC enflurane or sevofluran...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02482745
更新日期:1994-03-01 00:00:00
abstract:PURPOSE:Ultrasound (US)-guided continuous interscalene brachial plexus block (CBPB) is known to provide effective pain relief for arthroscopic rotator cuff repair. This study was conducted to compare analgesic efficacy and forearm muscle tone of the basal infusion rate and bolus dose of 0.2 % ropivacaine for US-guided ...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-013-1681-x
更新日期:2014-02-01 00:00:00
abstract:PURPOSE:Numerous reports suggest that intravenously administered (IV) anesthetics affect postsynaptic events in the central nervous system. However, there is little evidence about how general anesthetics influence the presynaptic processes. The level of presynaptic calcium (Ca(2+)) concentration ([Ca(2+)](pre)) regulat...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-011-1186-4
更新日期:2011-10-01 00:00:00
abstract::In this case series study, we prospectively examined whether it might be possible to check the effect of spinal anesthesia (SA), based on the disappearance of lower extremity reflexes and spasticity, in patients with spinal cord injury (SCI), in whom the effect cannot be confirmed by the pinprick test or by using the ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-012-1429-z
更新日期:2012-12-01 00:00:00
abstract::There is little evidence of gastric excretion after ingestion of solids. We examined gastric emptying times after ingesting normal breakfast in healthy adult volunteer using ultrasonography. Eight adult volunteers fasted for 8 h, and we examined the gastric antral area in the right lateral decubitus position using ult...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-019-02694-6
更新日期:2019-12-01 00:00:00
abstract::The impact of postoperative atrial fibrillation (PAF) on patient outcomes has prompted intense investigation into the optimal methods for prevention and treatment of this complication. In the prevention of PAF, β-blockers and amiodarone are particularly effective and are recommended by guidelines. However, their use r...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
doi:10.1007/s00540-012-1330-9
更新日期:2012-06-01 00:00:00
abstract::Within the airway management field, simulation has been used as a tool of training for over 40 years. Simulation training offers a chance of active involvement for the trainees. It can effectively enhance and upgrade the knowledge and skills of the trainees in airway management, and subsequently decrease medical error...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
doi:10.1007/s00540-015-2116-7
更新日期:2016-04-01 00:00:00
abstract::Although rare, a change in visual acuity after surgery for nonocular procedures has devastating consequences. Increased recognition and discussion of this complication is reported in recent literature, most notably following spinal and cardiac surgery. Various pathologies may be responsible for perioperative visual lo...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
doi:10.1007/s00540-013-1648-y
更新日期:2013-12-01 00:00:00
abstract::The pharmacokinetics and pharmacodynamics of vecuronium bromide were studied in patients under general anesthesia of enflurane and nitrous oxide in oxygen. Eighteen patients were randomly divided into two groups which received either 0.05 mg.kg(-1) (low dose group) or 0.20 mg.kg(-1) (high dose group) of vecuronium int...
journal_title:Journal of anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s0054020060028
更新日期:1992-01-01 00:00:00
abstract:PURPOSE:The properties of two new-generation CO(2) absorbents, Amsorb Plus (Armstrong Medical, Coleraine, UK) and Drägersorb Free (Drager, Lubeck, Germany), were compared with those of Amsorb (Armstrong Medical) and Sodasorb II (W.R. Grace, Lexington, MA, USA). METHODS:The concentration of compound A produced by each ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-004-0253-5
更新日期:2004-01-01 00:00:00
abstract:PURPOSE:Newborns are often sedated during MRI but sedation itself creates adverse events and management is more challenging in this environment. Oral glucose/sucrose administration has been studied in newborns during painful procedures; however, its effectiveness in keeping newborns sleepy and motionlessness during pai...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-016-2296-9
更新日期:2017-04-01 00:00:00
abstract:PURPOSE:In many countries, patients are generally allowed to have clear fluids until 2-3 h before surgery. In Japan, long preoperative fasting is still common practice. To shorten the preoperative fasting period in Japan, we tested the safety and efficacy of oral rehydration therapy until 2 h before surgery. METHODS:T...
journal_title:Journal of anesthesia
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00540-011-1261-x
更新日期:2012-02-01 00:00:00
abstract::The incidence of an abnormal increase in the serum levels of glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) following anesthesia with halothane and 65% nitrous oxide in oxygen (halothane group) or with sevoflurane and 65% nitrous oxide in oxygen (sevoflurane group) was compared in wome...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02479843
更新日期:1995-06-01 00:00:00
abstract::We encountered three cases of lung disorders caused by drowning in the recent large tsunami that struck following the Great East Japan Earthquake. All three were females, and two of them were old elderly. All segments of both lungs were involved in all the three patients, necessitating ICU admission and endotracheal i...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-011-1273-6
更新日期:2012-04-01 00:00:00
abstract::Muscle relaxation induced by neuromuscular blocking agents (NMBAs) is necessary for tracheal intubation and immobilization during surgery. Although acetylcholinesterase inhibitors have been successfully used as antagonists for NMBAs, they have their limitations; their effects are transient and ineffective against prof...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-020-02836-1
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:It seems controversial whether or not neutrophil elastase inhibitors are effective in attenuating myocardial ischemia/reperfusion injury. We thus investigated possible protective effects of sivelestat, a neutrophil elastase inhibitor, against myocardial stunning i.e., prolonged myocardial dysfunction following ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-010-0948-8
更新日期:2010-08-01 00:00:00
abstract:PURPOSE:We investigated whether presynaptic facilitatory M1 and/or inhibitory M2 muscarinic receptors contributed to pancuronium- and cisatracurium-induced tetanic fade. METHODS:Phrenic nerve-diaphragm muscle preparations of rats were indirectly stimulated with tetanic frequency (75 +/- 3.3 Hz; mean +/- SD). Doses of ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-009-0790-z
更新日期:2009-01-01 00:00:00
abstract::Optimal visualization of the glottis can be crucial to successful laryngoscopy. Limited information has been published on the light intensity delivered from laryngoscopes powered by rechargeable batteries. In this study the laryngoscope light intensity delivered from 10 nickel metal hydride (NiMH), 7 nickel cadmium (N...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1618-4
更新日期:2013-10-01 00:00:00
abstract::We measured free and total catecholamine in ten patients undergoing coronary artery-bypass grafting under high-dose fentanyl (93.9 +/- 2.2 microg.kg(-1), mean +/- SE) anesthesia. Arterial blood samples were obtained: 1) before induction of anesthesia (control), 2) 1 min after intubation, 3) 1 min after skin incision, ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054030070086
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:Peripheral gangrene (PG) is a known complication requiring limb amputation among sepsis survivors; however, its incidence and associated risk factors remain controversial. We aimed to examine the incidence of limb amputation among sepsis survivors, and to investigate factors independently associated with limb a...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-020-02858-9
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND:We hypothesized that body shape metrics influence the anatomy of spinal canal and intraabdominal pressure in three dimensions. We explored the effects of abdominal circumference, trunk length, and their combination on the level of spinal anesthesia in the term parturient in this study. METHODS:Thirty term p...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1715-4
更新日期:2014-04-01 00:00:00
abstract::In many anesthesia textbooks written in English, lidocaine, tetracaine, bupivacaine, ropivacaine, and chloroprocaine are listed as useful local anesthetics for spinal anesthesia. In contrast, T-cain is not included in these lists, even though it has been reported to be suitable for spinal anesthesia in Japan. T-cain w...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
doi:10.1007/s00540-015-2066-0
更新日期:2015-10-01 00:00:00
abstract:PURPOSE:Patients in whom neutropenia recovery is complicated by pneumonia have an increased risk of acute lung injury (ALI) and detrimental outcomes. The aim of the present study was to investigate whether inhibition of neutrophil elastase (NE) is effective in lipopolysaccharide (LPS)-induced ALI during neutropenia rec...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-017-2311-9
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Rocuronium (Rb) is ideal for continuous infusion but has a widely variable duration of action. We investigated the distribution of Rb infusion in a steady state of optimal muscle relaxation and the relationship between the measured and predicted blood Rb concentrations in laparoscopic surgery. METHODS:Seven...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-014-1879-6
更新日期:2015-02-01 00:00:00
abstract::Tracheomalacia after thyroidectomy is a life-threatening situation. However, it is difficult to predict postoperative tracheal obstruction with certainty. A case of a 74-year-old woman with a long-standing adenomatous goiter (98 g) is reported. She had undergone partial right lobe thyroidectomy 54 years earlier. After...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-011-1181-9
更新日期:2011-10-01 00:00:00
abstract::Beta-adrenergic blockers (β-blockers) are clearly indicated for the long-term treatment of patients with systolic heart failure and post-acute myocardial infarction. Early small-scale studies reported their potential benefits for perioperative use; subsequent randomized controlled trials, however, failed to reproduce ...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
doi:10.1007/s00540-019-02691-9
更新日期:2020-02-01 00:00:00
abstract::This study investigated right ventricular (RV) performance during hypotensive anesthesia and compared the effect of the vasodilators prostaglandin E1 (PGE1), nicardipine HCl (Nic), glycerin trinitrate (GTN), and isosorbide dinitrate (ISDN) on RV function. Fifty patients were allocated into four groups [PGE1 (n=20), Ni...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02480070
更新日期:1997-06-01 00:00:00
abstract::We report here a 59-year-old man with a saber-sheath tracheal narrowing who was scheduled to undergo pharyngeal tumor resection under general anesthesia. The tracheal narrowing was not clearly detected by chest radiography during the preoperative examination, but it was visible on axial computed tomography (CT) images...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-009-0841-5
更新日期:2010-02-01 00:00:00
abstract:PURPOSE:Atrial arrhythmias are common after non-cardiac thoracic surgery. We tested the hypothesis that TEA reduces the risk of new-onset atrial arrhythmias after pulmonary resection. METHODS:We evaluated patients who had pulmonary resection. New-onset atrial arrhythmias detected before hospital discharge was our prim...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-014-1865-z
更新日期:2015-02-01 00:00:00
abstract::The acute neuroinflammatory response to surgery may play a key pathogenic role in postoperative delirium (POD). Here, we investigated the contribution of acute postoperative pain to neuroinflammation and related delirium-like behaviors after surgery in adult and aged rats. Animals were assigned into four groups: contr...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-019-02635-3
更新日期:2019-06-01 00:00:00