Abstract:
PURPOSE:Facemask ventilation during the induction of general anesthesia in paediatric patients remains a challenge as it may result in hypoxic conditions and gastric insufflation with subsequent regurgitation and aspiration. So far, it is unclear if pressure-controlled or manual facemask ventilation is preferable in children. We hypothesized that pressure-controlled ventilation in apnoeic children results in lower peak airway pressure and flow rates compared to manual ventilation at comparable respiratory rates and tidal volumes. METHODS:Sixty-two lung-healthy children undergoing scheduled ear-nose-throat surgery were included in the study. After the induction of anesthesia, the patient's lungs were consecutively ventilated via a facemask in either manual or pressure-controlled mode, in randomized order. The primary outcome measure was peak airway pressure. Secondary outcome measures included positive end-expiratory pressure, airway compliance, tidal volume and airway flow. RESULTS:Data of 52 patients could be analyzed. Pressure-controlled ventilation resulted in a lower mean and peak inspiratory pressure (both p < 0.001), airway pressure amplitude (p = 0.01) and inspiratory peak flow rate (p = 0.005) compared to manual ventilation. The ratio of inspiration to expiration time was lower in pressure-controlled ventilation compared to manual ventilation (p < 0.001). CONCLUSION:Pressure-controlled facemask ventilation during induction of anesthesia in pediatric patients results in lower airway pressure, and lower flow rates compared to manual ventilation, at comparable tidal and minute volumes.
journal_name
J Anesthjournal_title
Journal of anesthesiaauthors
Goebel U,Schumann S,Wirth Sdoi
10.1007/s00540-018-2580-ysubject
Has Abstractpub_date
2019-02-01 00:00:00pages
33-39issue
1eissn
0913-8668issn
1438-8359pii
10.1007/s00540-018-2580-yjournal_volume
33pub_type
杂志文章,随机对照试验abstract::It is recommended that the period of fasting before elective surgery should be shortened to facilitate a rapid recovery by preventing catabolism. We examined the effects of a short period of fasting on metabolism by performing indirect calorimetry (IC) under general anesthesia. A prospective observational study involv...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-014-1950-3
更新日期:2015-06-01 00:00:00
abstract::We encountered three cases of lung disorders caused by drowning in the recent large tsunami that struck following the Great East Japan Earthquake. All three were females, and two of them were old elderly. All segments of both lungs were involved in all the three patients, necessitating ICU admission and endotracheal i...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-011-1273-6
更新日期:2012-04-01 00:00:00
abstract:PURPOSE:Nowadays the size of the streamlined liner of the pharynx airway (SLIPA™) is selected by matching the width of the thyroid cartilage of the patient to the widest dimension of the SLIPA™. The objective of this work was to improve the method of selection by matching the distance between the otobasion inferius and...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-013-1571-2
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:The relationship between preoperative hyperglycemia and postoperative acute kidney injury (AKI) occurrence in non-cardiac surgery including laparoscopic surgery remains unclear. This study aimed to assess the relationship between preoperative chronic hyperglycemia and postoperative AKI occurrence after a maj...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-018-2551-3
更新日期:2018-10-01 00:00:00
abstract::Cervical spinal cord injury is a rare but serious complication after general anesthesia. The risk factors include traumatic cervical injury, cervical spine instability, and difficult airway management. It has also occurred in the absence of cervical instability. Here we report a patient who had a history of intermitte...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1667-8
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVES:When physicians become patients, they may expect special privileges, extra attention from caregivers, and non-routine treatments. Consequently, physician patients may not be treated per routine-which possibly worsens care rather than improving it. We thus tested the primary hypothesis that in-hospital mortal...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-016-2273-3
更新日期:2017-02-01 00:00:00
abstract:PURPOSE:The aim of this study was to determine the hemodynamic and blood gas effects of inhalational anesthetics on the maternal-fetal sheep unit. The principal hypothesis, tested in chronically instrumented near-term pregnant ewes, was that sevoflurane anesthesia may be safe and useful for the mother and fetus during ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-009-0763-2
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:There are no sufficient evidences for the sedative effect of gabapentin during anesthesia, especially intravenous sedation (IVS). The purpose of this study was to evaluate the sedative effect of gabapentin as preanesthetic medication during the IVS with propofol. METHODS:10 volunteer subjects joined this study...
journal_title:Journal of anesthesia
pub_type: 临床试验,杂志文章
doi:10.1007/s00540-018-2559-8
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:Transthoracic esophagectomy is an invasive surgery, and the excessive surgical stress produces inflammatory cytokines, which provoke acute respiratory distress syndrome (ARDS). Sivelestat sodium hydrate-a selective neutrophil elastase inhibitor-is used to treat or prevent ARDS in patients undergoing esophagecto...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-018-2602-9
更新日期:2019-04-01 00:00:00
abstract::This study investigated right ventricular (RV) performance during hypotensive anesthesia and compared the effect of the vasodilators prostaglandin E1 (PGE1), nicardipine HCl (Nic), glycerin trinitrate (GTN), and isosorbide dinitrate (ISDN) on RV function. Fifty patients were allocated into four groups [PGE1 (n=20), Ni...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02480070
更新日期:1997-06-01 00:00:00
abstract:PURPOSE:The general public's perceptions of anesthesia and the risks associated with it may be skewed. The outpatient preoperative appointment with an anesthesiologist allows for patient education regarding different anesthetic options and counseling regarding anxiety related to anesthesia and surgery. This study inves...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-018-02608-y
更新日期:2019-04-01 00:00:00
abstract::Enzyme inhibition on anaerobic dehalogenation of halothane by various analgesic or hypnotic agents was investigated in vitro using rat liver microsomal fraction. The production rate of chloro-difluoro-ethylene (CDE) and chloro-trifluoro-ethane (CTE), anaerobic metabolites of halothane, was measured when various concen...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054010050331
更新日期:1991-10-01 00:00:00
abstract::Adenosine triphosphate as well as sodium nitroprusside has been used for hypotensive anesthesia. The purpose of this study was to examine the possibility that two hypotensive drugs may exert different effects on venous capacitance during controlled hypotension. In rats anesthetized with ketamine, mean arterial pressur...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054070010143
更新日期:1987-09-01 00:00:00
abstract:PURPOSE:Vascular risk factors, including metabolic syndrome, are known to contribute to the development of cognitive dysfunction. We tested the hypothesis that patients with metabolic syndrome are more likely to develop cognitive dysfunction after noncardiac surgery. METHODS:Age- and education-balanced patients (n = 6...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-011-1137-0
更新日期:2011-06-01 00:00:00
abstract:PURPOSE:The CO(2) reactivity of cortical cerebral vessels and local cortical blood flow (l-CoBF) were evaluated during anesthesia in patients with moyamoya disease who were undergoing revascularization surgery. METHODS:Using laser-Doppler flowmetry, the CO(2) reactivity of cortical cerebral vessels and l-CoBF were mea...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s005400050043
更新日期:1999-01-01 00:00:00
abstract:PURPOSE:A large proportion of patients experience chronic post-surgical pain (CPSP) following inguinal hernia repair surgery. The aim of this study was to investigate the predictive risk factors and protective factors for CPSP following inguinal hernia surgery. METHODS:After institutional ethics approval was obtained,...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-020-02743-5
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:"Juci", one of the traditional acupuncture techniques, means contralateral acupuncture; i.e., implanting a needle into an acupoint to treat a given disease or disorder, but on the side of the body opposite to the diseased side. The aim of this study was: (1) to assess acupuncture effects on formalin-induced noc...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-006-0443-4
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:Peripheral gangrene (PG) is a known complication requiring limb amputation among sepsis survivors; however, its incidence and associated risk factors remain controversial. We aimed to examine the incidence of limb amputation among sepsis survivors, and to investigate factors independently associated with limb a...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-020-02858-9
更新日期:2021-02-01 00:00:00
abstract:PURPOSE:To investigate the differences in recovery of postural stability, after obtaining similar intravenous sedation levels with midazolam, in elderly and younger patients undergoing dental surgery. METHODS:We studied 15 elderly patients (>65 years) and 15 younger patients (<55 years) after intravenous sedation. Mid...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s005400200024
更新日期:2002-01-01 00:00:00
abstract:PURPOSE:Flexible fiber-optic bronchoscope-guided orotracheal intubation is a valuable technique with demonstrated benefits in the management of difficult airways. Despite its popularity with anesthesia providers, the technique is not fail-safe and airway-related complications secondary to failed intubation attempts rem...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-014-1920-9
更新日期:2015-04-01 00:00:00
abstract:PURPOSE:We assessed the accuracy of a point-of-care blood gas analyzer in providing data from saline samples obtained by gastrointestinal tonometry (Tonometrics Catheter; Tonometrics Division, Instrumentarium, Helsinki, Finland) for the calculation of intramucosal pH (pHi) and the P(CO)(2) gap (intramucosal P(CO)(2) - ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-003-0209-1
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Inguinal hernia repair is a common procedure, and can be performed under spinal anesthesia. Although adequate analgesia is crucial to postoperative recovery, the optimal protective analgesic regimen remains to be established. PURPOSE:To investigate the effects of preoperative etoricoxib within a protective ...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-017-2368-5
更新日期:2017-10-01 00:00:00
abstract::The acute neuroinflammatory response to surgery may play a key pathogenic role in postoperative delirium (POD). Here, we investigated the contribution of acute postoperative pain to neuroinflammation and related delirium-like behaviors after surgery in adult and aged rats. Animals were assigned into four groups: contr...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-019-02635-3
更新日期:2019-06-01 00:00:00
abstract:PURPOSE:We evaluated the hemodynamic and respiratory effects of dexmedetomidine in intubated, spontaneously breathing patients after endoscopic submucosal dissection (ESD) for cervical esophageal or pharyngeal cancer. METHODS:This retrospective study included 129 patients aged 66.5 ± 8.3 years, who underwent ESD under...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-016-2175-4
更新日期:2016-08-01 00:00:00
abstract::Laryngeal mask airway (LMA) insertion was tried in 120 pediatric cases, from 2 months to 12 years of age. Initial indications for LMA were the same as for a face mask, except for two additional conditions; anticipation of difficulty with intubation and difficulty in management by a face mask. Size 2 LMA was used in th...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054010050160
更新日期:1991-04-01 00:00:00
abstract:PURPOSE:In many countries, patients are generally allowed to have clear fluids until 2-3 h before surgery. In Japan, long preoperative fasting is still common practice. To shorten the preoperative fasting period in Japan, we tested the safety and efficacy of oral rehydration therapy until 2 h before surgery. METHODS:T...
journal_title:Journal of anesthesia
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00540-011-1261-x
更新日期:2012-02-01 00:00:00
abstract:PURPOSE:In emergency situations, rescuers occasionally must secure the airway while the patient is in a position other than the ideal supine position. We hypothesized that the laryngeal mask airway Supreme(®) (Supreme) may be useful for emergent airway management in several positions and compared the utility of the Sup...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-011-1145-0
更新日期:2011-08-01 00:00:00
abstract:PURPOSE:Volatile anesthetics affect the cardiovascular and immune systems. Toward a better understanding of the molecular mechanisms behind the modulation exerted by these agents, we focused on the effects of halothane and isoflurane on the activation of p38 mitogen-activated protein kinase (MAPK), which plays a critic...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-004-0237-5
更新日期:2004-01-01 00:00:00
abstract::Mechanical influences independent of chemoreceptor function on ventilatory control were studied in halothane-anesthetized, artificially ventilated patients using the technique reported by Altose et al. (Respir Physiol 66: 171-180, 1986). Contribution of mechanical factor was indirectly assessed by comparing the values...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054020060387
更新日期:1992-10-01 00:00:00
abstract:BACKGROUND:Emergency surgery itself induces high risk for postoperative mortality and morbidities; however, it remains unknown which concomitant pathological conditions of emergency surgeries are causative factors of deteriorating outcomes. This study examined the causal factors of postoperative mortality and morbidity...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1639-z
更新日期:2013-12-01 00:00:00