Roles of antibodies to influenza A virus hemagglutinin, neuraminidase, and M2e in conferring cross protection.

abstract：:We hypothesized that the mutational strand asymmetry is more strongly exerted upon the mitochondrial cytochrome b (Cytb) gene, which is distant from the origin of the light-strand replication (Ori(L)), than upon the ATPase subunit 6 (ATP6) gene, which is close to the Ori(L). To test this hypothesis, we determined the ...

journal_title：Biochemical and biophysical research communications

authors： Fuku N,Oshida Y,Takeyasu T,Guo LJ,Kurata M,Yamada Y,Sato Y,Tanaka M

更新日期：2002-02-01 00:00:00

abstract：:Neuronal hyperexcitability is identified as a critical pathological basis of epileptic seizures. Cholestane-3β, 5α, 6β-triol (Triol) is a major metabolic oxysterol of cholesterol. Although its neuroprotective effect on ischemia-induced neuronal injury and negative modulation of voltage-gated sodium (Nav) channels were...

journal_title：Biochemical and biophysical research communications

authors： Tang L,Yan M,Leng T,Yin W,Cai S,Duan S,Zhu W,Lin S,Huang J,Yan G,Zheng G,Chen Y

更新日期：2018-01-29 00:00:00

abstract：:Androstenedione is reduced to form testosterone by 17-beta-hydroxysteroid dehydrogenase (17 beta HSD) and two different reductive isoforms of the enzyme have been identified (types 1 and 3). In this study, levels of mRNA encoding both reductive isoforms have been measured during fetal and post-natal development in the...

journal_title：Biochemical and biophysical research communications

authors： Sha J,Baker P,O'Shaughnessy PJ

更新日期：1996-05-06 00:00:00

abstract：:Yeast Ccc2 is a P-type ATPase responsible for transport of copper(I) from the cytosol to the trans-Golgi network. It possesses a soluble cytosolic N-terminal region containing two copper(I)-binding domains. Homologous eukaryotic copper-transporting ATPases have from one to six domains. We have expressed a fragment enc...

journal_title：Biochemical and biophysical research communications

authors： Banci L,Bertini I,Chasapis CT,Rosato A,Tenori L

更新日期：2007-12-21 00:00:00

abstract：:To investigate the role of activation of c-Jun NH2-terminal kinase 1 (JNK1) in mediating cisplatin-induced apoptosis and the possibility of induction of JNK activity in triggering relation to DNA damage and drug resistance. We investigated the difference of cisplatin-induced activation of JNK pathway and H2O2 alterati...

journal_title：Biochemical and biophysical research communications

authors： Li F,Meng L,Zhou J,Xing H,Wang S,Xu G,Zhu H,Wang B,Chen G,Lu YP,Ma D

更新日期：2005-10-07 00:00:00

abstract：:The relationship between colorectal cancer (CRC) and cholesterol has been confirmed for many years, but the mechanism was not very clear. miR-33a was important in cholesterol metabolism and was abnormally expressed in many tumors, thus our study hypothesized that cholesterol effect on CRC by regulating miR-33a and its...

journal_title：Biochemical and biophysical research communications

authors： Wang Y,Liu C,Hu L

更新日期：2019-04-09 00:00:00

abstract：:Hepatitis C virus (HCV) infects its target cells in the form of cell-free viruses and through cell-cell contact. Here we report that HCV is associated with exosomes. Using highly purified exosomes and transmission electron microscopic imaging, we demonstrated that HCV occurred in both exosome-free and exosome-associat...

journal_title：Biochemical and biophysical research communications

authors： Liu Z,Zhang X,Yu Q,He JJ

更新日期：2014-12-12 00:00:00

abstract：:The effect of vitamin A on the expression of apoAI and CIII genes in intact rats was studied. In vitamin A-deficient rats, the hepatic level of apoAI mRNA was increased and enhanced by an oral administration of excess retinoic acid(RA). A similar administration to normal rats caused an increase in the apoAI mRNA level...

journal_title：Biochemical and biophysical research communications

authors： Nagasaki A,Kikuchi T,Kurata K,Masushige S,Hasegawa T,Kato S

更新日期：1994-12-30 00:00:00

abstract：:The uncharacterized Saccharomyces cerevisiae proteins Fcf1 and Fcf2, encoded by the ORFs YDR339c and YLR051c, respectively, were identified in a tandem affinity purification experiment of the known 40S factor Faf1p. Most of the proteins associated with TAP-Faf1p are trans-acting factors involved in pre-rRNA processing...

journal_title：Biochemical and biophysical research communications

authors： Rempola B,Karkusiewicz I,Piekarska I,Rytka J

更新日期：2006-07-28 00:00:00

abstract：:There are very few reports on antifungal proteins from rhizomes and there is none from the family of Zingiberaceae. An antifungal protein with a novel N-terminal sequence was isolated from ginger rhizomes utilizing a protocol that involved ion exchange chromatography on DEAE-cellulose, affinity chromatography on Affi-...

journal_title：Biochemical and biophysical research communications

authors： Wang H,Ng TB

更新日期：2005-10-14 00:00:00

abstract：:Stem cells have been identified using the DNA-binding dye Hoechst 33342 and flow cytometry (FCM) in various tissues known as the side population (SP). The present study shows, for the first time, the presence of side population cells in human deciduous dental pulp cells (DPCs). Flow cytometric identification revealed ...

journal_title：Biochemical and biophysical research communications

authors： Wang J,Wei X,Ling J,Huang Y,Huo Y,Zhou Y

更新日期：2010-09-24 00:00:00

abstract：:Lipoprotein (a) [Lp(a)], a risk factor for coronary artery disease, is a LDL-like particle with apolipoprotein (a) [apo(a)] covalently linked to apolipoprotein B (apoB). Apo(a) has many repeats of kringle 4-like domain, classified as type 1 through type 10 (T1-T10). Deletion analysis was performed to define the functi...

journal_title：Biochemical and biophysical research communications

authors： Trieu VN,McConathy WJ

更新日期：1998-10-09 00:00:00

abstract：:Specification to primordial germ cells (PGCs) is mediated by mesoderm-induction signals during gastrulation. We found that Akt activation during in vitro mesodermal differentiation of embryonic stem cells (ESCs) generated self-renewing spheres with differentiation states between those of ESCs and PGCs. Essential regul...

journal_title：Biochemical and biophysical research communications

authors： Yamano N,Kimura T,Watanabe-Kushima S,Shinohara T,Nakano T

更新日期：2010-02-12 00:00:00

abstract：:We have developed a new method for monitoring the interactions between nonlabeled RNAs that involves detection of fluorescence resonance energy transfer (FRET) between two DNA probes with different fluorescent label. The sequences of the probes are complementary to those of the RNAs. In this study, we examined the int...

journal_title：Biochemical and biophysical research communications

authors： Ota N,Sato T,Taira K,Ohkawa J

更新日期：2001-12-21 00:00:00

abstract：:Recombinant baculoviruses expressing full length and 3' truncated forms of c-DNA encoding the Drosophila melanogaster acetylcholinesterase (AChE) were constructed. Biochemical analyses showed that full length recombinant protein was enzymatically active and anchored to the cell membrane via a glycolipidic residue. DTT...

journal_title：Biochemical and biophysical research communications

authors： Chaabihi H,Fournier D,Fedon Y,Bossy JP,Ravallec M,Devauchelle G,Cérutti M

更新日期：1994-08-30 00:00:00

abstract：:S-100 protein and annexin II2-p11(2) were reported to inhibit and to stimulate the assembly of glial fibrillary acidic protein (GFAP), respectively, in a Ca(2+)-dependent manner. Here we show by a number of experimental approaches that S-100 protein contrasts all the effects of annexin II2-p11(2) on GFAP assembly and,...

journal_title：Biochemical and biophysical research communications

authors： Bianchi R,Garbuglia M,Verzini M,Giambanco I,Spreca A,Donato R

更新日期：1995-03-28 00:00:00

abstract：:We attempted to attenuate neointimal formation following vascular injury using a retroviral suicide vector. Epicardial coronary arteries of adult miniature swine were injured by deployment of oversized tantalum stents. One week later, injured segments were exposed to packaged retroviral constructs with or without the ...

journal_title：Biochemical and biophysical research communications

authors： Barbee RW,Stapleton DD,Madras DE,Ré RN,Murgo JP,Davenport WD,Giardina J,Cook JL

更新日期：1995-02-06 00:00:00

abstract：:Arginine decarboxylase (ADC) catalyzes the first step of polyamine (PA) biosynthesis to produce putrescine (Put) from arginine (Arg). One of the 2 Arabidopsis ADC genes, AtADC2, is induced in response to salt stress causing the accumulation of free Put. To analyze the roles of stress-inducible AtADC2 gene and endogeno...

journal_title：Biochemical and biophysical research communications

authors： Urano K,Yoshiba Y,Nanjo T,Ito T,Yamaguchi-Shinozaki K,Shinozaki K

更新日期：2004-01-09 00:00:00

abstract：BACKGROUND:When an activated muscle is rapidly stretched, force rises and peaks while muscle lengthens. The peak force is normally called critical-force (Pc). The mechanism behind this increase in force is not well understood, but it has been associated with crossbridges operating in different states. METHODS:Myofibri...

journal_title：Biochemical and biophysical research communications

authors： Minozzo FC,Altman D,Rassier DE

更新日期：2015-08-07 00:00:00

abstract：:BRAF25 is an alternatively spliced protein of BRAF35 (see associated paper). We have mapped the BRAF25 gene to chromosome sub-band 19p13.3, a region where loss of chromosomal heterozygosity has been reported in about 50% of ovarian cancers. Because of the high incidence of genetic links of prostate cancer to breast an...

journal_title：Biochemical and biophysical research communications

authors： Wang C,McCarty IM,Balazs L,Li Y,Steiner MS

更新日期：2002-07-05 00:00:00

abstract：:JMJD2A-D belong to the JmjC domain-containing family of histone demethylases. JMJD2D is the most structurally divergent JMJD2 protein as it lacks the PHD and Tudor domains present in JMJD2A-C. Here, we systematically analyzed the histone demethylase specificity of JMJD2 proteins in vivo. We found that JMJD2A and C dem...

journal_title：Biochemical and biophysical research communications

authors： Shin S,Janknecht R

更新日期：2007-02-23 00:00:00

abstract：:Using the broad host-range vector R751 to provide transfer functions, plasmid pVAL-1 and transposon Tn4351 were conjugally mobilized from Escherichia coli into Porphyromonas gingivalis. Transfer frequencies for both elements varied between 10(-6) and 10(-11), depending upon the recipient. The behavior of pVAL-1 and Tn...

journal_title：Biochemical and biophysical research communications

authors： Dyer DW,Bilalis G,Michel JH,Malek R

更新日期：1992-07-31 00:00:00

abstract：:The mitochondrial respiratory chain (MRC) supplies the majority of the energy requirements of most eucaryotic cells. A null mutation in the Caenorhabditis elegans nuo-1 gene encoding a subunit of complex I (NADH-ubiquinone oxidoreductase) is lethal, leading to a developmental arrest at the third larval stage. To ident...

journal_title：Biochemical and biophysical research communications

authors： Ndegwa S,Lemire BD

更新日期：2004-07-09 00:00:00

abstract：:Chironomus ramosus is known to tolerate high doses of gamma radiation exposure. Larvae of this insect possess more than 95% of hemoglobin (Hb) in its circulatory hemolymph. This is a comparative study to see effect of gamma radiation on Hb of Chironomus and humans, two evolutionarily diverse organisms one having extra...

journal_title：Biochemical and biophysical research communications

authors： Gaikwad PS,Panicker L,Mohole M,Sawant S,Mukhopadhyaya R,Nath BB

更新日期：2016-08-05 00:00:00

abstract：:Atrial natriuretic factor (isoleucine ANF 101-126), cleaved ANF (isoleucine ANF 101-105/106-126) and des (Gln 18, Ser 19, Gly 20, Leu 21, Gly 22) ANF 4-23-NH2 (C-ANF 4-23) stimulated cyclic guanosine monophosphate production (cGMP) by rat aortic vascular smooth muscle cells (VSMC) in culture. Cleaved ANF and ANF C4-23...

journal_title：Biochemical and biophysical research communications

authors： Abell TJ,Richards AM,Yandle TG,Espiner EA,Frampton C,Ikram H

更新日期：1989-10-16 00:00:00

abstract：:It is well-documented that large amounts of endotoxin produce hemorrhagic mucosal lesions in the stomach. To determine whether endotoxin, when injected at small doses, similarly exerts ulcerogenic actions, endotoxin (0.4-40 micrograms/kg) was injected into 24 hr-fasted rats. These small doses of endotoxin did not affe...

journal_title：Biochemical and biophysical research communications

authors： Tsuji K,Uehara A,Santos SB,Namiki M

更新日期：1993-12-30 00:00:00

abstract：:The vibrational frequency of CO bound to myoglobin can be varied by up to 60 cm-1 by making site-specific mutations in the distal pocket. These changes may result from specific chemical interactions between distal amino acids and the CO or from changes in the electrostatic field of the distal pocket. In this paper, we...

journal_title：Biochemical and biophysical research communications

authors： Decatur SM,Boxer SG

更新日期：1995-07-06 00:00:00

abstract：:Autophagy is a physiologically regulated and evolutionary conserved process that plays a critical role in degradation of cytoplasmic proteins and other macromolecules within the lysosomes. Beclin-1, the mammalian orthologue of yeast Atg6, is an important mediator of autophagy that has been studied in many human cancer...

journal_title：Biochemical and biophysical research communications

authors： Kapoor V,Paliwal D,Baskar Singh S,Mohanti BK,Das SN

更新日期：2012-06-15 00:00:00

abstract：:Stellate cell profibrotic gene induction and transdifferentiation are central events in liver fibrosis. Oxidative stress has been implicated as an activator of the transcription factors Nrf2 and AP-1 through shared kinase signaling pathways that also purportedly contribute to stellate cell activation. The present stud...

journal_title：Biochemical and biophysical research communications

authors： Reichard JF,Petersen DR

更新日期：2004-09-24 00:00:00

abstract：:Autophagy is an evolutionary conserved intracellular process whereby cells break down long-lived proteins and organelles. Accumulating evidences suggest increasing physiological significance of autophagy in pathogenesis of infectious diseases. Anthrax lethal toxin (LT) exerts its influence on numerous cells and herein...

journal_title：Biochemical and biophysical research communications

authors： Tan YK,Kusuma CM,St John LJ,Vu HA,Alibek K,Wu A

更新日期：2009-02-06 00:00:00