Participation of WNT and β-Catenin in Physiological and Pathological Endometrial Changes: Association with Angiogenesis.

abstract：:Novel and more effective treatment strategies against multiple myeloma (MM) have significantly prolonged patients' survival and raised interest in the depth of response and its association with clinical outcome. Minimal residual disease (MRD) has emerged as one of the most relevant prognostic factors in MM and should ...

journal_title：BioMed research international

authors： Fulciniti M,Munshi NC,Martinez-Lopez J

更新日期：2015-01-01 00:00:00

abstract：:The purpose of this paper is to review some of the psychological and neural mechanisms behind mindfulness practice in order to explore the unique factors that account for its positive impact on emotional regulation and health. After reviewing the mechanisms of mindfulness and its effects on clinical populations we wil...

journal_title：BioMed research international

authors： Grecucci A,Pappaianni E,Siugzdaite R,Theuninck A,Job R

更新日期：2015-01-01 00:00:00

abstract：:Hypertrophic Scars (HTSs) are a complex fibroproliferative disorder, and their exact mechanism is still not fully understood. In this study, we first found that cystic fibrosis transmembrane conductance regulator (CFTR) expression was downregulated in human hypertrophic scars at the RNA and protein levels by microarra...

journal_title：BioMed research international

authors： Zhou Y,Zhao Y,Du H,Suo Y,Chen H,Li H,Liang X,Li Q,Huang X

更新日期：2020-01-02 00:00:00

abstract：:The use of in vitro metabolism data to predict human clearance has become more significant in the current prediction of large scale drug clearance for all the drugs. The relevant information (in vitro metabolism data and in vivo human clearance values) of thirty-five drugs that satisfied the entry criteria of probe dr...

journal_title：BioMed research international

authors： Wang L,Chiang C,Liang H,Wu H,Feng W,Quinney SK,Li J,Li L

更新日期：2015-01-01 00:00:00

abstract：:Salinity is a major environmental stress that limits crop production worldwide. In this study, we characterized plant growth-promoting rhizobacteria (PGPR) containing 1-aminocyclopropane-1-carboxylate (ACC) deaminase and examined their effect on salinity stress tolerance in okra through the induction of ROS-scavenging...

journal_title：BioMed research international

authors： Habib SH,Kausar H,Saud HM

更新日期：2016-01-01 00:00:00

abstract：:Background. Monitoring the epidemiology of cardiovascular risk factors (CRFs) and their determinants is important to develop appropriate recommendations to prevent cardiovascular diseases in specific risk groups. The NESCaV study was designed to collect standardized data to estimate the prevalence of CRFs in relation ...

journal_title：BioMed research international

authors： Streel S,Donneau AF,Hoge A,Majerus S,Kolh P,Chapelle JP,Albert A,Guillaume M

更新日期：2015-01-01 00:00:00

abstract：:Immunodeficiency is associated with higher cancer incidence. However, it is unknown whether there is a link between immunodeficiency and development of multiple primary malignancies. In the present study we analyse this link focusing on kidney-transplanted patients, as they are at higher risk of developing cancer due ...

journal_title：BioMed research international

authors： Santangelo ML,Criscitiello C,Renda A,Federico S,Curigliano G,Dodaro C,Scotti A,Tammaro V,Calogero A,Riccio E,Pisani A,Carlomagno N

更新日期：2015-01-01 00:00:00

abstract：:The large-scale production of cardiomyocytes is a key step in the development of cell therapy and tissue engineering to treat cardiovascular diseases, particularly those caused by ischemia. The main objective of this study was to establish a procedure for the efficient production of cardiomyocytes by reprogramming mes...

journal_title：BioMed research international

authors： Zanetti BF,Gomes WJ,Han SW

更新日期：2013-01-01 00:00:00

abstract：Background:Yes-associated protein 1 (YAP1) is an effector of Hippo pathway, which plays a significant role in cell proliferation and tumor progression. The relationship between YAP1 and gastrointestinal cancer has been explored in many previous studies. We conducted a meta-analysis to explore the prognostic effect of Y...

journal_title：BioMed research international

authors： Zhang L,Song X,Li X,Wu C,Jiang J

更新日期：2018-11-14 00:00:00

abstract：:This study was conducted to evaluate the effect of mesenchymal stem cells (MSCs) and a novel curcumin derivative (NCD) on HepG2 cells (hepatoma cell line) and to investigate their effect on Notch1 signaling pathway target genes. HepG2 cells were divided into HepG2 control group, HepG2 cells treated with MSC conditione...

journal_title：BioMed research international

authors： Abdel Aziz MT,Khaled HM,El Hindawi A,Roshdy NK,Rashed LA,Sabry D,Hassouna AA,Taha F,Ali WI

更新日期：2013-01-01 00:00:00

abstract：:Shigellosis is a global human health problem and the incidence is highest among children. In the present work, main Shigella virulence genes was examined by PCR and compared to symptoms of pediatric shigellosis. Thirty Shigella isolates were identified from an etiologic study at which 1,339 children ranging 0-10 years...

journal_title：BioMed research international

authors： da Cruz CB,de Souza MC,Serra PT,Santos I,Balieiro A,Pieri FA,Nogueira PA,Orlandi PP

更新日期：2014-01-01 00:00:00

abstract：:Human diseases are abnormal medical conditions in which multiple biological components are complicatedly involved. Nevertheless, most contributions of research have been made with a single type of genetic data such as Single Nucleotide Polymorphism (SNP) or Copy Number Variation (CNV). Furthermore, epigenetic modifica...

journal_title：BioMed research international

authors： Kang M,Kim DC,Liu C,Gao J

更新日期：2015-01-01 00:00:00

abstract：:Spasticity is the velocity-dependent increase in muscle tone due to the exaggeration of stretch reflex. It is only one of the several components of the upper motor neuron syndrome (UMNS). The central lesion causing the UMNS disrupts the balance of supraspinal inhibitory and excitatory inputs directed to the spinal cor...

journal_title：BioMed research international

authors： Trompetto C,Marinelli L,Mori L,Pelosin E,Currà A,Molfetta L,Abbruzzese G

更新日期：2014-01-01 00:00:00

abstract：:Volatiles emitted by the host's food would be the first signals used by parasitoids in the host location process and are thought to play an important role in host habitat location. In this study, the olfactory responses of Theocolax elegans (Westwood), a Pteromalid wasp that parasitizes immature stages of stored-produ...

journal_title：BioMed research international

authors： Germinara GS,De Cristofaro A,Rotundo G

更新日期：2016-01-01 00:00:00

abstract：:Stem cell-based therapy has been considered as a promising option in the treatment of ischemic heart disease. Although stem cell administration resulted in the temporary improvement of myocardial contractility in the majority of studies, the formation of new cardiomyocytes within the injured myocardium has not been co...

journal_title：BioMed research international

authors： Belostotskaya G,Hendrikx M,Galagudza M,Suchkov S

更新日期：2020-03-03 00:00:00

abstract：:This study investigated the influence of gene-gene and gene-environment interactions on the risk of developing asbestosis. The study comprised 262 cases with asbestosis and 265 controls with no asbestos-related disease previously studied for MnSOD, ECSOD, CAT, GSTT1, GSTM1, GSTP1, and iNOS polymorphisms. Data on cumul...

journal_title：BioMed research international

authors： Franko A,Dolžan V,Arnerić N,Dodič-Fikfak M

更新日期：2013-01-01 00:00:00

abstract：:Hitherto, limited clinical impact has been achieved in the treatment of glioblastoma (GBMs). Although phytochemicals found in medicinal herbs can provide mankind with new therapeutic remedies, single agent intervention has failed to bring the expected outcome in clinical trials. Therefore, combinations of several agen...

journal_title：BioMed research international

authors： Elkady AI,Hussein RA,Abu-Zinadah OA

更新日期：2014-01-01 00:00:00

abstract：:To understand the progression of recovery in postural stability and physical functioning after patients received the minimally invasive total hip arthroplasty (MTHA), we monitor the pain level, functional capacity, and postural stability before and after operation within one year. In total of 23 subjects in our study,...

journal_title：BioMed research international

authors： Chang CJ,Lin NL,Lee MS,Chern JS

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:Suppressor of cytokine signaling 7 (SOCS7) is a member of the SOCS family and is known to interact with phospholipase Cγ-1 (PLCγ-1), a key downstream mediator of the hepatocyte growth factor (HGF)/C-MET axis. Here, we report our observations of the effect of knocking down SOCS7 gene on the behaviour of breast c...

journal_title：BioMed research international

authors： Sasi W,Ye L,Jiang WG,Sharma AK,Mokbel K

更新日期：2014-01-01 00:00:00

abstract：:Three-dimensional (3D) liver tumor segmentation from Computed Tomography (CT) images is a prerequisite for computer-aided diagnosis, treatment planning, and monitoring of liver cancer. Despite many years of research, 3D liver tumor segmentation remains a challenging task. In this paper, an efficient semiautomatic meth...

journal_title：BioMed research international

authors： Wu W,Wu S,Zhou Z,Zhang R,Zhang Y

更新日期：2017-01-01 00:00:00

abstract：:Chromosome rearrangements and fusion genes present major portion of leukemogenesis and contribute to leukemic subtypes. It is practical and helpful to detect the fusion genes in clinic diagnosis of leukemia. Present application of reverse transcription polymerase chain reaction (RT-PCR) method to detect the fusion gen...

journal_title：BioMed research international

authors： Xiong FF,Li BS,Zhang CX,Xiong H,Shen SH,Zhang QH

更新日期：2013-01-01 00:00:00

abstract：:Apc-mutated Pirc rats, spontaneously developing intestinal tumours, are resistant to 1,2-dimethylhydrazine- (DMH-) induced colon apoptosis. To understand this phenomenon, we analyzed the expression of genotoxic stress-related genes Mgmt, Gsta1, and Gstp1 in the colon of wt and Pirc rats in basal conditions and 24 h af...

journal_title：BioMed research international

authors： Femia AP,Luceri C,Lodovici M,Crucitta S,Caderni G

更新日期：2016-01-01 00:00:00

abstract：:A comparison of the superior and inferior rectus muscles was performed to determine whether they have similar structures and innervation attributable to their participation in the same type of, although antagonistic, eye movements. The study was conducted on 70 cadaveric hemiheads, and the anatomical variations in the...

journal_title：BioMed research international

authors： Haładaj R,Polguj M,Tubbs RS

更新日期：2020-04-30 00:00:00

abstract：:Kawasaki disease (KD) is an acute systemic vasculitis of childhood with prolonged fever, and the diagnosis of KD is mainly based on clinical criteria, which is prone to misdiagnosis with other febrile infectious (FI) diseases. Currently, there remain no effective molecular markers for KD diagnosis. In this study, we a...

journal_title：BioMed research international

authors： Zhong J,Huang Q,Wang Y,Gao H,Jia H,Fan J,Liang H

更新日期：2020-04-26 00:00:00

abstract：UNLABELLED:The aim of the study was to determine the effect of different muscle length and visual feedback information (VFI) on accuracy of isometric contraction of elbow flexors in men after an ischemic stroke (IS). MATERIALS AND METHODS:Maximum voluntary muscle contraction force (MVMCF) and accurate determinate musc...

journal_title：BioMed research international

authors： Juodzbaliene V,Darbutas T,Skurvydas A,Brazaitis M

更新日期：2016-01-01 00:00:00

abstract：:We previously found that the greatest salivation response in healthy human subjects is produced by facial vibrotactile stimulation of 89 Hz frequency with 1.9 μ m amplitude (89 Hz-S), as reported by Hiraba et al. (2012, 20011, and 2008). We assessed relationships between the blood flow to brain via functional near-inf...

journal_title：BioMed research international

authors： Hiraba H,Inoue M,Gora K,Sato T,Nishimura S,Yamaoka M,Kumakura A,Ono S,Wakasa H,Nakayama E,Abe K,Ueda K

更新日期：2014-01-01 00:00:00

abstract：:The present work reports the anticancer, antioxidant, lipo-protective, and anti-HIV activities of phytoconstituents present in P. hysterophorus leaf. Dried leaf samples were sequentially extracted with nonpolar and polar solvents. Ethanol fraction showed noticeable cytotoxic activity (81-85%) in SRB assay against MCF-...

journal_title：BioMed research international

authors： Kumar S,Chashoo G,Saxena AK,Pandey AK

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND AIM:Trace elements and vitamins play a vital role in human body to perform its function properly. Thalassemic patients are at risk of micronutrient deficiency. This study estimated levels of vitamins A, C, E, B12, folic acid, total homocysteine (tHcy), and methylmalonic acid (MMA) along with trace elemen...

journal_title：BioMed research international

authors： Sherief LM,Abd El-Salam SM,Kamal NM,El Safy O,Almalky MA,Azab SF,Morsy HM,Gharieb AF

更新日期：2014-01-01 00:00:00

abstract：:Metabolomics in maternal-fetal medicine is still an "embryonic" science. However, there is already an increasing interest in metabolome of normal and complicated pregnancies, and neonatal outcomes. Tissues used for metabolomics interrogations of pregnant women, fetuses and newborns are amniotic fluid, blood, plasma, c...

journal_title：BioMed research international

authors： Fanos V,Atzori L,Makarenko K,Melis GB,Ferrazzi E

更新日期：2013-01-01 00:00:00

abstract：Purpose:Accumulated evidence suggests that reproductive factors are related to different breast cancer subtypes, but most studies on these relationships are mainly focused on middle-aged and older patients, and it remains unclear how reproductive factors impact different subtypes of breast cancer in young women. Metho...

journal_title：BioMed research international

authors： Wang JM,Wang J,Zhao HG,Liu TT,Wang FY

更新日期：2020-04-06 00:00:00