Evidence for clathrin mobilization during directed phagocytosis of Shigella flexneri by HEp2 cells.

abstract：:This study aims to investigate whether IL-10 regulate decidual Treg cells apoptosis to reverse the abnormal pregnancy outcomes with Toxoplasma gondii (T. gondii) infection. Recombinant mouse IL-10 (rIL-10) treatment and IL-10 deficiency (IL-10(-/-)) abnormal pregnancy animal models with T. gondii infection were establ...

journal_title：Microbial pathogenesis

authors： Lao K,Zhao M,Li Z,Liu X,Zhang H,Jiang Y,Wang Y,Hu X

更新日期：2015-12-01 00:00:00

abstract：:Vibrio parahaemolyticus is a leading cause of seafood-associated bacterial gastroenteritis. The pathogen produces the thermostable direct hemolysin (TDH), which is the sole cause of the Kanagawa phenomenon (KP), a special β-type haemolysis in the Wagatsuma agar. TDH also exerts several other biological activities, the...

journal_title：Microbial pathogenesis

authors： Cai Q,Zhang Y

更新日期：2018-10-01 00:00:00

abstract：:Mouse macrophages activated by gamma interferon (IFN-gamma) and bacterial lipopolysaccharide (LPS) are highly cytotoxic for the enteric protozoan parasite Entamoeba histolytica. Herein, we show that this killing by activated macrophages is L-arginine dependent, inasmuch as it was blocked by exogenous arginase or NG-mo...

journal_title：Microbial pathogenesis

authors： Denis M,Ghadirian E

更新日期：1992-03-01 00:00:00

abstract：:Toxoplasma species are obligate intracellular protozoan which are responsible for induction of several forms of Toxoplasmosis in humans. The mechanisms responsible for the progression of the prolonged forms of Toxoplasmosis and associated pathologies are yet to be identified. However, previous studies proposed that im...

journal_title：Microbial pathogenesis

authors： Zare-Bidaki M,Hakimi H,Abdollahi SH,Zainodini N,Arababadi MK,Kennedy D

更新日期：2014-04-01 00:00:00

abstract：:Chlamydia pneumoniae has been linked to atherosclerotic heart disease. However, there is a limited knowledge by which C. pneumoniae gain access to atheromatous lesions. The adhesion of C. pneumoniae -infected circulatory component(s) to endothelium and smooth muscle cells represents the first step in an inflammatory r...

journal_title：Microbial pathogenesis

authors： Kaul R,Wenman WM

更新日期：2001-03-01 00:00:00

abstract：:A cytotoxin to Vero cells (Shiga-like toxin), which was neutralized by antibody against purified Shiga toxin produced by Shigella dysenteriae 1, was purified from Escherichia coli O157:H7, isolated from a patient with hemorrhagic colitis. The purification procedure consisted of ammonium sulfate fractionation, DEAE-cel...

journal_title：Microbial pathogenesis

authors： Noda M,Yutsudo T,Nakabayashi N,Hirayama T,Takeda Y

更新日期：1987-05-01 00:00:00

abstract：:In the Staphylococcus aureus ATCC25923 strain, the flqB mutation in the 5'untranslated region (5'UTR) of the norA gene causes increased norA mRNA expression and high efflux activity (HEA). The involvement of the norA gene 5'UTR in HEA has not been explored in S. epidermidis; therefore, we examined the function of this...

journal_title：Microbial pathogenesis

authors： García-Gómez E,Jaso-Vera ME,Juárez-Verdayes MA,Alcántar-Curiel MD,Zenteno JC,Betanzos-Cabrera G,Peralta H,Rodríguez-Martínez S,Cancino-Díaz ME,Jan-Roblero J,Cancino-Diaz JC

更新日期：2017-02-01 00:00:00

abstract：:Pasteurella haemolytica leukotoxin (LKT) is a member of the RTX family of pore-forming toxins that kill bovine immune cells. Several studies have suggested that RTX toxins kill target cells by the induction of apoptosis. In the present study, BL3 bovine leukaemia cells were exposed to LKT and assessed by molecular and...

journal_title：Microbial pathogenesis

authors： Wang JF,Kieba IR,Korostoff J,Guo TL,Yamaguchi N,Rozmiarek H,Billings PC,Shenker BJ,Lally ET

更新日期：1998-12-01 00:00:00

abstract：:Clostridium difficile causes serious and potentially fatal inflammatory diseases of the colon. Two large protein toxins, TcdA and TcdB, have been clearly implicated in pathogenesis. The goal of this study was to determine whether the glucosyltransferase activity of the toxins is critical for the induction of tumor nec...

journal_title：Microbial pathogenesis

authors： Sun X,He X,Tzipori S,Gerhard R,Feng H

更新日期：2009-06-01 00:00:00

abstract：:Bovine leukemia virus (BLV) is transcriptionally silent in most circulating peripheral blood mononuclear cells (PBMCs) of animals with well-established infections. Using PBMCs from a newly infected sheep, we asked whether viral transcription proceeded differently during the initial months of infection, when the preval...

journal_title：Microbial pathogenesis

authors： Radke K,Sigala TJ,Grossman D

更新日期：1992-05-01 00:00:00

abstract：:The therapeutic use of probiotics for supporting the antibiotic action against gastrointestinal disorders is a current trend and emerging applications have gained popularity because of their support for various microbiological activities in digestive processes. Microorganisms isolated from kefir with great probiotic p...

journal_title：Microbial pathogenesis

authors： Lima MDSF,Souza KMS,Albuquerque WWC,Teixeira JAC,Cavalcanti MTH,Porto ALF

更新日期：2017-09-01 00:00:00

abstract：:Opportunistic infections, due to disease-related immunosuppression, constitute the major cause of death in American visceral leishmaniasis (AVL). Sera from these patients (AVL sera) non-specifically inhibit the in vitro proliferative response of normal human lymphocytes to lectins or antigens. In the present work, the...

journal_title：Microbial pathogenesis

authors： Soares NM,Ferraz TP,Nascimento EG,Carvalho EM,Pontes-de-Carvalho L

更新日期：2006-06-01 00:00:00

abstract：:Chronic burn wound infections caused by Stapyhylococcus aureus (S. aureus) are largely associated with biofilm formation. However, the mechanism by which S. aureus form biofilm in clinical environments is far less understood. In the present study we addressed the association between biofilm formation and membrane vesi...

journal_title：Microbial pathogenesis

authors： He X,Yuan F,Lu F,Yin Y,Cao J

更新日期：2017-09-01 00:00:00

abstract：:In this experimental study, the Allium essential oil (AHEO) was extracted through the hydrodistillation method. AHEO components were identified through gas chromatography/mass spectrometry (GC/MS), and its antioxidant properties and total phenolic content were examined through the methods of 2,2-diphenyl-1-picrylhydra...

journal_title：Microbial pathogenesis

authors： Alizadeh Behbahani B,Imani Fooladi AA

更新日期：2018-01-01 00:00:00

abstract：:The re-emerging field of phage therapy is the potential biocontrol agents for the transfer of virulence factor and to kill their bacterial hosts. In this study, the lytic Vibrio vulnificus phages were studied to provide a better understanding of phage-host interactions and development of phage therapy. Four new V. vul...

journal_title：Microbial pathogenesis

authors： Srinivasan P,Ramasamy P

更新日期：2017-10-01 00:00:00

abstract：:Influenza virus is responsible for significant morbidity and mortality worldwide. Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is the major cause of death in influenza virus infected patients. Recent studies indicated that active glucagon like peptide-1 (GLP-1) encoded by glucagon (GCG) gene exer...

journal_title：Microbial pathogenesis

authors： Bai Y,Lian P,Li J,Zhang Z,Qiao J

更新日期：2020-12-05 00:00:00

abstract：:CpG DNA is a potent activator of the innate immune system. Here the protective effects of CpG DNA are assessed against the facultative intracellular pathogen Francisella tularensis. Dosing of mice with CpG DNA provided protection against disease caused by F. tularensis subsp. holarctica live vaccine strain (LVS) but d...

journal_title：Microbial pathogenesis

authors： Rees DG,Hartley MG,Green M,Lukaszewski RA,Griffin KF,Atkins HS,Lyons R,Krieg AM,Titball RW

更新日期：2013-10-01 00:00:00

abstract：:Salmonella spp. have been investigated as live vaccine vectors because they are heat stable and can elicit humoral, cellular, and secretory immune responses. However, the expression of some foreign antigens is toxic to bacterial vectors. We therefore studied an approach for the controlled expression of antigen in Salm...

journal_title：Microbial pathogenesis

authors： Ervin SE,Small PA Jr,Gulig PA

更新日期：1993-08-01 00:00:00

abstract：:Cold shock proteins (Csps) are small and highly conserved proteins that have target RNA- and DNA-binding activities. Csps play roles in different cellular processes and show functional redundancy. Ralstonia solanacearum, the agent of bacterial wilt, has 4 or 5 Csps based on genome analysis. However, the functions of a...

journal_title：Microbial pathogenesis

authors： Liu Y,Tan X,Cheng H,Gong J,Zhang Y,Wang D,Ding W

更新日期：2020-02-20 00:00:00

abstract：:Salmonella belongs to the Enterobacteriaceae family which is widely distributed in the environment due to its adaptive capacity to stress conditions. In addition, Salmonella is able to perform a type of cell-to-cell communication called quorum sensing, which leads to differential gene expression. The quorum sensing sy...

journal_title：Microbial pathogenesis

authors： Almeida FA,Vargas ELG,Carneiro DG,Pinto UM,Vanetti MCD

更新日期：2018-08-01 00:00:00

abstract：:Host cell invasion is important for periodontal pathogens in evading host defenses and spreading into deeper areas of the periodontal tissue. Treponema denticola has been implicated in a number of potentially pathogenic processes, including periodontal tissue penetration. Here we tested the ability of T. denticola str...

journal_title：Microbial pathogenesis

authors： Inagaki S,Kimizuka R,Kokubu E,Saito A,Ishihara K

更新日期：2016-05-01 00:00:00

abstract：:T lymphocyte-mediated immunity is important for resistance to Francisella tularensis. To characterize the specificity of this immunity, we used membrane proteins and two lipopolysaccharide (LPS) preparations. Both membrane proteins were heat-modifiable, as indicated by their migration in sodium dodecyl sulphate polyac...

journal_title：Microbial pathogenesis

authors： Surcel HM,Sarvas M,Helander IM,Herva E

更新日期：1989-12-01 00:00:00

abstract：:Edwardsiella tarda, an important fish pathogenic bacterium, could utilize type III secretion system (T3SS) to transfer multiple effector proteins into host cells during infection. EseG was identified to be an E. tarda T3SS effector, which could be injected by T3SS into non-phagocytic cells. Since E. tarda is a faculta...

journal_title：Microbial pathogenesis

authors： Fang S,Zhang L,Lou Y,Yang D,Wang Q,Zhang Y,Liu Q

更新日期：2016-08-01 00:00:00

abstract：:Toxoplasma gondii is one of the most successful intracellular protozoan parasites in the world, which can infect most warm-blooded animals including foxes in the world and cause toxoplasmosis. This is the first meta-analysis to assess the overall prevalence and potential risk factors of T. gondii among foxes in the wo...

journal_title：Microbial pathogenesis

authors： Wei XY,Gao Y,Lv C,Wang W,Chen Y,Zhao Q,Gong QL,Zhang XX

更新日期：2020-12-28 00:00:00

abstract：:Thanks to the progress and decreasing costs in genome sequencing technologies, more than 250,000 bacterial genomes are currently available in public databases, covering most, if not all, of the major human-associated phylogenetic groups of these microorganisms, pathogenic or not. In addition, for many of them, sequenc...

journal_title：Microbial pathogenesis

authors： Anani H,Zgheib R,Hasni I,Raoult D,Fournier PE

更新日期：2020-12-01 00:00:00

abstract：:Based on the in-depth study of type III secretion systems (T3SS) in pathogenic bacteria, approaches targeting T3SS have become new alternative strategies to combat drug-resistant bacterial infections. As an important food-borne pathogen, Salmonella enterica serovar Typhimurium (S. Typhimurium) injects effector protein...

journal_title：Microbial pathogenesis

authors： Lv Q,Lv Y,Dou X,Wassy SL,Jia G,Wei L,Yu Q,Deng X,Zhang C,Wang J

更新日期：2021-01-05 00:00:00

abstract：BACKGROUND:Periodontitis is a persistent polymicrobial infection, which leads to chronic inflammation in the tooth supporting tissues. Aggregatibacter actinomycetemcomitans are normal commensals of oral cavity but are low in number in periodontally healthy subjects. They are one of the major pathogens aetiologically li...

journal_title：Microbial pathogenesis

authors： Gadekar NB,Hosmani JV,Bhat KG,Kotrashetti VS,Nayak RS,Babji DV,Pattanshetty SM,Joshi VM,Bansode RA

更新日期：2018-12-01 00:00:00

abstract：:Clinical isolates of Pseudomonas aeruginosa are either invasive or cytotoxic towards mammalian epithelial cells, endothelial cells, and macrophages. Invasion requires host cell actin cytoskeleton function, and ExsA-regulated proteins of P. aeruginosa that inhibit invasion (ExoS and ExoT) can disrupt the cytoskeleton. ...

journal_title：Microbial pathogenesis

authors： Evans DJ,Kuo TC,Kwong M,Van R,Fleiszig SM

更新日期：2002-09-01 00:00:00

abstract：:Because of the close genetic relatedness between apes and humans, apes are susceptible to many human infectious agents and can serve as carriers of these pathogens. Consequently, they present a serious health hazard to humans. Moreover, many emerging infectious diseases originate in wildlife and continue to threaten h...

journal_title：Microbial pathogenesis

authors： Keita MB,Hamad I,Bittar F

更新日期：2014-12-01 00:00:00

abstract：:Staphylococcus aureus (S. aureus) is a major cause of pneumonia that often affects young and immunocompetent patients. Inflammation plays an important role in the development of S. aureus-induced pneumonia. Geniposide, a major iridoid glucoside component of gardenia fruit, has been reported to have anti-inflammatory a...

journal_title：Microbial pathogenesis

authors： Yu B,Shen Y,Qiao J,Cui Q

更新日期：2017-11-01 00:00:00