TLR4 in Toxoplasmosis; friends or foe?

abstract：:Cold shock proteins (Csps) are small and highly conserved proteins that have target RNA- and DNA-binding activities. Csps play roles in different cellular processes and show functional redundancy. Ralstonia solanacearum, the agent of bacterial wilt, has 4 or 5 Csps based on genome analysis. However, the functions of a...

journal_title：Microbial pathogenesis

authors： Liu Y,Tan X,Cheng H,Gong J,Zhang Y,Wang D,Ding W

更新日期：2020-02-20 00:00:00

abstract：:Staphylococcus aureus is one of the major bacterial mastitis pathogens with significant effects on animal and human health. Some studies showed that S. aureus strains that infect different host species are genetically distinct, although most strains can infect a wide range of host species. However, there are no clearl...

journal_title：Microbial pathogenesis

authors： Vaughn JM,Abdi RD,Gillespie BE,Kerro Dego O

更新日期：2020-07-01 00:00:00

abstract：:Mouse macrophages activated by gamma interferon (IFN-gamma) and bacterial lipopolysaccharide (LPS) are highly cytotoxic for the enteric protozoan parasite Entamoeba histolytica. Herein, we show that this killing by activated macrophages is L-arginine dependent, inasmuch as it was blocked by exogenous arginase or NG-mo...

journal_title：Microbial pathogenesis

authors： Denis M,Ghadirian E

更新日期：1992-03-01 00:00:00

abstract：:Diagnosis of toxoplasmosis is an important issue, especially in at-risk patients. The molecular methods showed a promising future for such diagnosis; however, the method itself and the target sequence to be detected is an important part of accurate detection of the infection. The aim of the present study was to evalua...

journal_title：Microbial pathogenesis

authors： Valian HK,Mirhendi H,Mohebali M,Shojaee S,Fallahi S,Jafari R,Kheirandish F,Mousavi P

更新日期：2020-03-01 00:00:00

abstract：:Ectoine, the most prominent osmolyte in nature, is a vital compatible solute present in halophilic bacterium. It protects the cellular biomolecules of the halophilic bacteria and retains their intrinsic function from extreme circumstances. In the current research, ectoine biosynthesis gene cluster (ectABC) in Bacillus...

journal_title：Microbial pathogenesis

authors： Anburajan L,Meena B,Sreelatha T,Vinithkumar NV,Kirubagaran R,Dharani G

更新日期：2019-11-01 00:00:00

abstract：:The emergence of extensive antibiotics resistant bacteria increased the demands for finding out new sources of antimicrobial agents. Marine niches were reported to be rich in many competent producers of significant bioactive compounds. On the course of screening program for new antimicrobials, a Bacillus strain was is...

journal_title：Microbial pathogenesis

authors： Lotfy WA,Mostafa SW,Adel AA,Ghanem KM

更新日期：2018-11-01 00:00:00

abstract：:Pathogenic yersiniae undergo an established low calcium response (LCR) at 37 degrees C in Ca2+-deficient media characterized by restricted growth with synthesis of Lcr plasmid-encoded virulence functions. The latter include outer membrane peptides (Yops) known to undergo Pst plasmid-mediated post-translational degrada...

journal_title：Microbial pathogenesis

authors： Mehigh RJ,Sample AK,Brubaker RR

更新日期：1989-03-01 00:00:00

abstract：:Staphylococcus aureus (S. aureus) is one of several opportunistic microbial pathogens associated with many healthcare problems. In the present study, S. aureus was assessed for its biofilm-forming ability on materials routinely used in dental offices, including stainless steel (SS), polyethylene (PE), and polyvinyl ch...

journal_title：Microbial pathogenesis

authors： Merghni A,Bekir K,Kadmi Y,Dallel I,Janel S,Bovio S,Barois N,Lafont F,Mastouri M

更新日期：2017-02-01 00:00:00

abstract：:A DNA fragment from Bordetella pertussis, encoding the fim2 fimbrial subunit gene with adjacent sequences, was used as a probe for the detection of homologous sequences in chromosomal DNA of Bordetella avium. A 1.8 kb Sa1I-PstI fragment from the genome of B. avium, which hybridized with the probe, was isolated and seq...

journal_title：Microbial pathogenesis

authors： Savelkoul PH,de Groot LE,Boersma C,Livey I,Duggleby CJ,van der Zeijst BA,Gaastra W

更新日期：1993-09-01 00:00:00

abstract：:Mycobacterium tuberculosis (Mtb) has coevolved with a human host to evade and exploit the immune system in multiple ways. Mtb is an enormously successful human pathogen that can remain undetected in hosts for decades without causing clinical disease. While tuberculosis (TB) represents a perfect prototype of host-patho...

journal_title：Microbial pathogenesis

authors： Baindara P

更新日期：2019-05-01 00:00:00

abstract：:Salmonella enterica serovar Pullorum (S. Pullorum) is a worldwide poultry pathogen of considerable economic importance, particularly in those countries with a developing poultry industry. A variety of genes that affect S. Pullorum colonization in chickens had been identified. 2',3'-cyclic phosphodiesterase (cpdB) is t...

journal_title：Microbial pathogenesis

authors： Liu H,Chen L,Wang X,Si W,Wang H,Wang C,Liu S,Li G

更新日期：2015-03-01 00:00:00

abstract：:The search for new antimicrobial drugs has been necessary due to the increased bacterial resistance to antibiotics currently in use, and natural products play an important role in this field. The aim of this study was to evaluate the in vitro effect of cinnamaldehyde on S. epidermidis strains, biofilm set-up preventio...

journal_title：Microbial pathogenesis

authors： Albano M,Crulhas BP,Alves FCB,Pereira AFM,Andrade BFMT,Barbosa LN,Furlanetto A,Lyra LPDS,Rall VLM,Júnior AF

更新日期：2019-01-01 00:00:00

abstract：:During the course of infection, Yersinia enterocolitica invades tissues where macrophages and polymorphonuclear leucocytes (PMNs) constitute the first line of defence. As expression of virulence in Y. enterocolitica is governed in part by a c. 70 kilobase virulence plasmid (pYV), we investigated the influence of this ...

journal_title：Microbial pathogenesis

authors： Tabrizi SN,Robins-Browne RM

更新日期：1992-09-01 00:00:00

abstract：:The present context was aimed to investigate the antibacterial potency of aqueous extract of coriander (Coriandrum sativum L.) leaves against bacterial pathogens isolated from the organs associated with digestive system of rabbit. This study also evaluated the influence of varied doses of aqueous extract of C. sativum...

journal_title：Microbial pathogenesis

authors： Mariezcurrena-Berasain MA,Velázquez-Garduño G,Marín-Mendoza PM,Pliego AB,Vega Castillo LF,Carranza BV,Khusro A,Ugbogu EA,Salem AZM

更新日期：2018-10-01 00:00:00

abstract：:Mycobacterium ulcerans, a decaying Mycobacterium marinum derivative is responsible for Buruli ulcer, a notifiable non-contagious disabling infection highly prevalent in some West African countries. Aquatic environments are suspected to host M. ulcerans, however, the exact reservoirs remain unknown. While M. marinum wa...

journal_title：Microbial pathogenesis

authors： Bouam A,Ghigo E,Drancourt M

更新日期：2018-01-01 00:00:00

abstract：:About 90% of tuberculosis (TB) patients latently infected with Mycobacterium tuberculosis (Mtb) show no symptoms, yet have a 10% chance in lifetime to progress active TB. Nevertheless, current diagnosis approaches need improvement in efficiency and sensitivity. The objective of this work was to detect potential signat...

journal_title：Microbial pathogenesis

authors： Sun Y,Weng Y,Zhang Y,Yan X,Guo L,Wang J,Song X,Yuan Y,Chang FY,Wang CL

更新日期：2017-06-01 00:00:00

abstract：:Brucellosis, a disease caused by the gram-negative bacterium Brucella spp., is a widespread zoonosis that inflicts important animal and human health problems, especially in developing countries. One of the hallmarks of Brucella infection is its capacity to establish a chronic infection, characteristic that depends on ...

journal_title：Microbial pathogenesis

authors： Spera JM,Comerci DJ,Ugalde JE

更新日期：2014-02-01 00:00:00

abstract：:Outer membrane and secreted proteins were isolated from Leptospira interrogans serovar pomona and characterized by sodium dodecyl sulfate polyacrylamide gel electrophoresis, immunoblot and radioimmunoprecipitation techniques. The L. interrogans outer membranes were extracted with Triton X-114 and contained several pro...

journal_title：Microbial pathogenesis

authors： Zuerner RL,Knudtson W,Bolin CA,Trueba G

更新日期：1991-04-01 00:00:00

abstract：:Our previous studies have shown that the adhesive ability of Enterococcus faecalis is dependent on the strain and is further modified by growth in serum. The data reported here demonstrate that E. faecalis adherence is mediated by carbohydrate residues present on the bacterial cell surface. Some of these (D-mannose an...

journal_title：Microbial pathogenesis

authors： Guzmàn CA,Pruzzo C,Platè M,Guardati MC,Calegari L

更新日期：1991-12-01 00:00:00

abstract：:It was recently shown that, as in yeast, alcohols selectively increase the hemolytic properties of certain staphylococci strains. This phenomenon has been called 'microbial alcohol-conferred hemolysis'(MACH). Here we present the changes in gene expression by Staphylococcus aureus 8325-4, in response to ethanol. Ethano...

journal_title：Microbial pathogenesis

authors： Korem M,Gov Y,Rosenberg M

更新日期：2010-02-01 00:00:00

abstract：:Apoptosis was considered as one of the important host defense mechanisms against mycobacteria infection. In macrophage, the main target cell of Mycobacterium tuberculosis, apoptosis after infection could help kill the bacillus inside and process the antigens for further presentation and proper immune response. Here, w...

journal_title：Microbial pathogenesis

authors： Tang J,Zhan L,Qin C

更新日期：2016-04-01 00:00:00

abstract：:Recently, microbial exopolysaccharides (EPSs) have offered very large field for medical applications owing to their bioactive characteristics. This study aimed to obtain antitumor EPS and to optimize its production using different optimization approaches. Eighty EPSs-producing bacteria were obtained from mud samples. ...

journal_title：Microbial pathogenesis

authors： Farag MMS,Moghannem SAM,Shehabeldine AM,Azab MS

更新日期：2020-03-01 00:00:00

abstract：:The changes in the cell surface carbohydrates of the eustachian tube (ET) and middle ear subsequent to the intranasal (i.n.) inoculation of Streptococcus pneumoniae (Spn) type 6A were studied in the chinchilla model of otitis media (OM) using a lectin histochemical technique with six different lectins (SNA, WGA, Succ ...

journal_title：Microbial pathogenesis

authors： Linder TE,Daniels RL,Lim DJ,DeMaria TF

更新日期：1994-06-01 00:00:00

abstract：:The failure of drugs for effective treatment against infectious diseases can be attributed to resistant forms of causative agents. The evasive nature of Mycobacterium tuberculosis is partly associated to its physical features, such as having a thick cell wall and incorporation of beneficial mutations leading to drug r...

journal_title：Microbial pathogenesis

authors： Rabha A,Singh A,Grover S,Kumari A,Pandey B,Grover A

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Cryptosporidiosis represents a major public health problem. This infection, caused by a protozoan parasite of the genus Cryptosporidium, has been reported worldwide as a frequent cause of diarrhoea. In the immunocompetent host, the typical watery diarrhea can be self-limiting. However, it is severe and chron...

journal_title：Microbial pathogenesis

authors： Chelbi H,Essid R,Jelassi R,Bouzekri N,Zidi I,Ben Salah H,Mrad I,Ben Sghaier I,Abdelmalek R,Aissa S,Bouratbine A,Aoun K

更新日期：2018-02-01 00:00:00

abstract：:Infectious urinary stones account for about 10% of all urinary stones. In 50% of cases urolithiasis is a recurrent illness, which can lead to the loss of a kidney if not properly treated. One of the reasons for recurrence of the disease may be the ability of bacteria to invade urothelial cells, persist in the host cel...

journal_title：Microbial pathogenesis

authors： Torzewska A,Budzyńska A,Białczak-Kokot M,Różalski A

更新日期：2014-06-01 00:00:00

abstract：:Fimbrial adhesins and hemolysins contribute to pathogenicity of extraintestinal Escherichia coli isolates causing urinary tract infections (UTI), sepsis and new born meningitis (NBM). Using gene cloning techniques and pulse field electrophoresis in combination with Southern hybridizations it was demonstrated that the ...

journal_title：Microbial pathogenesis

authors： Hacker J,Bender L,Ott M,Wingender J,Lund B,Marre R,Goebel W

更新日期：1990-03-01 00:00:00

abstract：:The gene (ystB) encoding the novel subtype of the heat-stable enterotoxin (Y-STb) was cloned from the chromosome of a clinical isolate of Yersinia enterocolitica 84-50 (serotype O:5, biotype 1A) and the nucleotide sequence was determined. The ystB contained 216 base pairs that encoded a protein of 71 amino acid residu...

journal_title：Microbial pathogenesis

authors： Ramamurthy T,Yoshino Ki,Huang X,Balakrish Nair G,Carniel E,Maruyama T,Fukushima H,Takeda T

更新日期：1997-10-01 00:00:00

abstract：:We obtained mutants devoid of the O1-antigen, the capsular polysaccharide (K antigen) or both from Klebsiella pneumoniae clinical isolates (urinary infection). These mutants were grown in urine, and their ability to fimbriate and to adhere were studied. Mutants lacking the O1-antigen, independently of the other surfac...

journal_title：Microbial pathogenesis

authors： Merino S,Rubires X,Aguilar A,Tomás JM

更新日期：1997-07-01 00:00:00

abstract：:The major limitation in histological examination of orally inoculated mice of Salmonella typhimurium has been the difficulty of attaining high enough levels for immunochemical detection. This problem has been solved by the use of confocal laser scanning microscopy (CLSM) analysis, which allows detection of bacteria in...

journal_title：Microbial pathogenesis

authors： Matsui H,Eguchi M,Kikuchi Y

更新日期：2000-07-01 00:00:00