Membrane proteins of Francisella tularensis LVS differ in ability to induce proliferation of lymphocytes from tularemia-vaccinated individuals.

abstract：:Siderophores are low molecular weight molecules that allow bacteria to acquire iron from host cell proteins. 2,3-dihydroxybenzoic acid (DHBA) is the only known siderophore produced by the intracellular pathogen Brucella abortus. Here its role in virulence was assessed by evaluating the ability of a mutant with a disru...

journal_title：Microbial pathogenesis

authors： Parent MA,Bellaire BH,Murphy EA,Roop RM 2nd,Elzer PH,Baldwin CL

更新日期：2002-05-01 00:00:00

abstract：:Respiratory infections caused by nontypeable Haemophilus influenzae (NTHi) are a major medical problem. Evidence suggests that the ability to form biofilms on mucosal surfaces may play a role in NTHi pathogenesis. However, the factors that contribute to NTHi biofilm cohesion remain largely unknown. In this study we in...

journal_title：Microbial pathogenesis

authors： Izano EA,Shah SM,Kaplan JB

更新日期：2009-04-01 00:00:00

abstract：:In this study we report the complete nucleotide sequence and genetic organization of the she pathogenicity island (PAI) of Shigella flexneri 2a strain YSH6000T. The 46 603 bp she PAI is situated adjacent to the 3' terminus of the pheV tRNA gene and includes an imperfect direct repeat of the 3'-terminal 22 bp of the ph...

journal_title：Microbial pathogenesis

authors： Al-Hasani K,Rajakumar K,Bulach D,Robins-Browne R,Adler B,Sakellaris H

更新日期：2001-01-01 00:00:00

abstract：:We have recently shown that a mouse lung infection model resulting in acute pneumonia could be used for evaluating the protective immunity induced by mucosal vaccines against Vibrio cholerae. In order to gain insight and better understanding of the pathogenicity of V. cholerae infection, we identified and compared pro...

journal_title：Microbial pathogenesis

authors： Kang SS,Baik JE,Yang JS,Cho K,Yun CH,Han SH

更新日期：2015-09-01 00:00:00

abstract：:Staphylococcus aureus (S. aureus) is a zoonotic bacterium and is among the most important pathogens causing bacterial foodborne diseases. In recent years, disease caused by antibiotic-resistant S. aureus is a serious clinical problem that poses a great threat to public health. In this study, we examined the drug-resis...

journal_title：Microbial pathogenesis

authors： Ma Y,Lan G,Li C,Cambaza EM,Liu D,Ye X,Chen S,Ding T

更新日期：2019-08-01 00:00:00

abstract：:Avian sarcoma virus (ASV)-induced tumor cells that are derived from regressing neoplasms contain about 75% less pp60src kinase activity than do progressively-growing tumor cells. Paradoxically, the polyadenylated RNAs extracted from 'regressor' cells found in regressing neoplasms are much more productive than those fr...

journal_title：Microbial pathogenesis

authors： Poulin L,Wainberg MA

更新日期：1987-02-01 00:00:00

abstract：:Sigma factor B (SigB) controls the expression of Staphylococcus aureus genes including virulence factors and plays a role in the bacterial secretion system through membrane vesicle production. Inhibition of SigB could attenuate SigB dependent virulence and secretion system. The objective of this study was to determine...

journal_title：Microbial pathogenesis

authors： Mitsuwan W,Jiménez-Munguía I,Visutthi M,Sianglum W,REIPI\/GEIH Study Group.,Rodríguez-Ortega MJ,Voravuthikunchai SP

更新日期：2019-03-01 00:00:00

abstract：:Infections with the obligate intracellular bacterium Chlamydia trachomatis are characterized by avoidance of fusion between chlamydia-containing endosomes and lysosomes, bacterial persistence and development of post-infectious sequelae. In this report we show that C. trachomatis induces apoptosis in McCoy and HeLa cel...

journal_title：Microbial pathogenesis

authors： Schöier J,Ollinger K,Kvarnström M,Söderlund G,Kihlström E

更新日期：2001-10-01 00:00:00

abstract：:The goal of this study was to demonstrate the participation in cellular damage of a Trichomonas vaginalis proteinase with a molecular mass of 65 kDa (CP65). By two dimensional gelatin-gel electrophoresis of trichomonad proteins we detected four spots with proteolytic activity on the 65 kDa region, but only one, pI 7.2...

journal_title：Microbial pathogenesis

authors： Alvarez-Sánchez ME,Avila-González L,Becerril-García C,Fattel-Facenda LV,Ortega-López J,Arroyo R

更新日期：2000-04-01 00:00:00

abstract：:Influenza virus is responsible for significant morbidity and mortality worldwide. Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is the major cause of death in influenza virus infected patients. Recent studies indicated that active glucagon like peptide-1 (GLP-1) encoded by glucagon (GCG) gene exer...

journal_title：Microbial pathogenesis

authors： Bai Y,Lian P,Li J,Zhang Z,Qiao J

更新日期：2020-12-05 00:00:00

abstract：:The reactivity of anti-pilus antibodies to native and denatured Haemophilus influenzae b (Hib) pili was studied using rabbit serum prepared against piliated H. influenzae b strain M43 (p+) and adsorbed with its non-piliated variant, strain M42 (p-). The specificity of the adsorbed serum for Hib pili was documented by ...

journal_title：Microbial pathogenesis

authors： Gilsdorf JR,Forney LJ,LiPuma JJ

更新日期：1989-10-01 00:00:00

abstract：:Synthesis of highly efficient antibacterial agents has become highly important due to emergence of antibiotic resistance. Herein, Pristine ZnO and ZnO-CuO nanocomposite has been synthesized by simple chemical co-precipitation method and characterized by X-ray diffraction (XRD), microscopic and spectroscopic techniques...

journal_title：Microbial pathogenesis

authors： Jan T,Azmat S,Mansoor Q,Waqas HM,Adil M,Ilyas SZ,Ahmad I,Ismail M

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Bacterial vaginosis (BV) is the most common vaginal infection in women of reproductive age. It shifts the paradigms of the vagina from healthy, beneficial microbiota to facultative and strict anaerobes. BV remains one of the most arduous and controversial challenges in modern-day clinical micr...

journal_title：Microbial pathogenesis

authors： Javed A,Manzoor S

更新日期：2020-12-01 00:00:00

abstract：:Infectious bronchitis (IB) is a highly contagious respiratory disease of chickens, which is caused by the infectious bronchitis virus (IBV). The innate immune response is crucial for antiviral infections and revealing the pathogenic mechanisms of IBV. In this study, we presents an evaluation of interferon (I, II and I...

journal_title：Microbial pathogenesis

authors： Yang X,Li J,Liu H,Zhang P,Chen D,Men S,Li X,Wang H

更新日期：2018-03-01 00:00:00

abstract：:Apoptosis was considered as one of the important host defense mechanisms against mycobacteria infection. In macrophage, the main target cell of Mycobacterium tuberculosis, apoptosis after infection could help kill the bacillus inside and process the antigens for further presentation and proper immune response. Here, w...

journal_title：Microbial pathogenesis

authors： Tang J,Zhan L,Qin C

更新日期：2016-04-01 00:00:00

abstract：:With the growing interest in probiotic microorganisms based on their well established immense health benefits, the present investigation was aimed to assess the adhesion potential and safety of probiotic Lactobacillus rhamnosus MTCC- 5897 (LR) before it can be put into a probiotic formulations. L. rhamnosus showed an ...

journal_title：Microbial pathogenesis

authors： Bhat MI,Singh VK,Sharma D,Kapila S,Kapila R

更新日期：2019-05-01 00:00:00

abstract：:Viral myocarditis (VMC) is a type of inflammation affecting myocardial cells caused by viral infection and has been an important cause of dilated cardiomyopathy (DCM) worldwide. Type B3 coxsackievirus (CVB3), a non-enveloped positive-strand RNA virus of the Enterovirus genus, is one of most common agent of viral myoca...

journal_title：Microbial pathogenesis

authors： Zhao Y,Yan K,Wang Y,Cai J,Wei L,Li S,Xu W,Li M

更新日期：2020-07-01 00:00:00

abstract：:Ehrlichia risticii, the causative agent of Potomac horse fever, is an obligate intracellular rickettsial organism. To understand the role of 55 and 51 kilodalton immunodominant antigens of E. risticii in strain variation, their genes from the 25-D and 90-12 strains were cloned, sequenced, and expressed in E. coli. Seq...

journal_title：Microbial pathogenesis

authors： Vemulapalli R,Biswas B,Dutta SK

更新日期：1998-06-01 00:00:00

abstract：:The type III secretion system of Pseudomonas aeruginosa, responsible for acute infection, is composed of over twenty proteins that facilitate cytotoxin injection directly into host cells. Integral to this process is production and secretion of PcrV. Administration of a recently developed, anti-PcrV immunoglobulin, eit...

journal_title：Microbial pathogenesis

authors： Lynch SV,Flanagan JL,Sawa T,Fang A,Baek MS,Rubio-Mills A,Ajayi T,Yanagihara K,Hirakata Y,Kohno S,Misset B,Nguyen JC,Wiener-Kronish JP

更新日期：2010-06-01 00:00:00

abstract：:Edwardsiella tarda poses a threat to human health and has resulted in enormous economic losses in aquaculture. Low temperatures are usually applied to contain the growth of this microorganism. In this study, stable isotope labelling by amino acids in cell culture (SILAC) was used to conduct comparative proteomic quant...

journal_title：Microbial pathogenesis

authors： Ma W,Jia J,Huang X,Xie W,Zhang X,Tang J,Lin C,Zhao L,Fang P

更新日期：2018-12-01 00:00:00

abstract：:Binding of human enterotoxigenic Escherichia coli (ETEC) to the small intestine is a prerequisite for colonization and is mediated by colonization factor (CF) antigens. Coli surface antigen 6 (CS6) is considered a CF but binding to isolated enterocytes has not been established. In this study bacteria expressing CS6 we...

journal_title：Microbial pathogenesis

authors： Helander A,Hansson GC,Svennerholm AM

更新日期：1997-12-01 00:00:00

abstract：:The addition of maltose to the growth media of Actinobacillus pleuropneumonia (serotype 1) resulted in the induction of an outer membrane protein (OMP) with a molecular mass of 42 kDa. This protein had porin-like properties in that it was peptidoglycan-associated and was resistant to proteolysis by trypsin. A pleuropn...

journal_title：Microbial pathogenesis

authors： Deneer HG,Potter AA

更新日期：1989-06-01 00:00:00

abstract：:Neisseria meningitidis is normally a human nasopharyngeal commensal but is also capable of causing life-threatening sepsis and meningitis. N. meningitidis secretes several virulence-associated proteins including Neisserial autotransporter lipoprotein (NalP), an immunogenic, type Va autotransporter harboring an S8-fami...

journal_title：Microbial pathogenesis

authors： Dufailu OA,Mahdavi J,Ala'Aldeen DAA,Wooldridge KG,Oldfield NJ

更新日期：2018-11-01 00:00:00

abstract：:Two-component regulatory proteins, histidine kinases and response regulators, function in bacteria as sensing and adaptive factors in response to a wide range of environmental stimuli. Conserved histidine and glycine regions of histidine kinase sensor proteins were used to design degenerate oligonucleotide primers for...

journal_title：Microbial pathogenesis

authors： Haydel SE,Dunlap NE,Benjamin WH Jr

更新日期：1999-04-01 00:00:00

abstract：:Porphyromonas gingivalis is highly implicated in the pathogenesis of periodontitis, which is characterized by the destruction of periodontal connective tissues and the supporting alveolar bone. Receptor Activator of NF-kappaB Ligand (RANKL) stimulates bone resorption, whereas osteoprotegerin (OPG) blocks its action, a...

journal_title：Microbial pathogenesis

authors： Belibasakis GN,Bostanci N,Hashim A,Johansson A,Aduse-Opoku J,Curtis MA,Hughes FJ

更新日期：2007-07-01 00:00:00

abstract：:Until recently, glycoproteins had only been described in eukaryotes. However, advances in detection methods and genome analyses have allowed the discovery of N-linked or O-linked glycoproteins, similar to those found in eukaryotes, in some bacterial species. These prokaryotic glycoproteins play roles in adhesion, solu...

journal_title：Microbial pathogenesis

authors： Shoji M,Nakayama K

更新日期：2016-05-01 00:00:00

abstract：:Brucellosis is a worldwide zoonotic infectious disease that has significant economic effects on animal production and human health. The host macrophage -Brucella interaction is critical to the establishment of infections. Thus, the kinetic transcriptional profile of gene expression in macrophages infected with the Bru...

journal_title：Microbial pathogenesis

authors： Liu Q,Han W,Sun C,Zhou L,Ma L,Lei L,Yan S,Liu S,Du C,Feng X

更新日期：2012-05-01 00:00:00

abstract：:Genital serovariants of Chlamydia trachomatis establish infection by attachment, entry and multiplication within human endometrial epithelial cells. In previous studies, a chlamydial recombinant Escherichia coli was identified which exhibited a specific adherent phenotype to endometrial epithelial cells closely resemb...

journal_title：Microbial pathogenesis

authors： Schmiel DH,Raulston JE,Fox E,Wyrick PB

更新日期：1995-10-01 00:00:00

abstract：:Staphylococcus aureus is a bacterial pathogen causing approximately 80% of all cases of human osteomyelitis. This bacterium can adhere to and become internalized by osteoblasts and previous studies indicate that osteoblasts are active in the internalization process. In the current study, we examined the roles of micro...

journal_title：Microbial pathogenesis

authors： Ellington JK,Reilly SS,Ramp WK,Smeltzer MS,Kellam JF,Hudson MC

更新日期：1999-06-01 00:00:00

abstract：:Influenza A virus infection plays a significant role in the pathogenesis of Streptococcus pneumoniae-induced acute otitis media in children. An understanding of how influenza A virus modulates host cellular responses is critically important in efforts to explore the molecular mechanisms of this synergism. We used micr...

journal_title：Microbial pathogenesis

authors： Tong HH,Long JP,Li D,DeMaria TF

更新日期：2004-10-01 00:00:00