Robust fluence map optimization via alternating direction method of multipliers with empirical parameter optimization.

abstract：:For proton therapy, an accurate conversion of CT HU to relative stopping power (RSP) is essential. Validation of the conversion based on real tissue samples is more direct than the current practice solely based on tissue substitutes and can potentially address variations over the population. Based on a novel dose exti...

journal_title：Physics in medicine and biology

authors： Zhang R,Baer E,Jee KW,Sharp GC,Flanz J,Lu HM

更新日期：2017-06-23 00:00:00

abstract：:Image-guided radiation therapy using implanted fiducial markers is a common solution for prostate localization to improve targeting accuracy. However, fiducials that are typically used for conventional photon radiotherapy cause large dose perturbations in patients who receive proton radiotherapy. A proposed solution h...

journal_title：Physics in medicine and biology

authors： Cheung J,Kudchadker RJ,Zhu XR,Lee AK,Newhauser WD

更新日期：2010-12-07 00:00:00

abstract：:In medical imaging different techniques have been developed to gain information from inside a tissue. Optoacoustics is a method to generate tomography pictures of tissue using Q-switched laser pulses. Due to thermal and pressure confinement, a short light pulse generates a pressure distribution inside tissue, which mi...

journal_title：Physics in medicine and biology

authors： Köstli KP,Frenz M,Bebie H,Weber HP

更新日期：2001-07-01 00:00:00

abstract：:Knowledge of what dose-volume histograms can be expected for a previously unseen patient could increase consistency and quality in radiotherapy treatment planning. We propose a machine learning method that uses previous treatment plans to predict such dose-volume histograms. The key to the approach is the framing of d...

journal_title：Physics in medicine and biology

authors： Skarpman Munter J,Sjölund J

更新日期：2015-09-07 00:00:00

abstract：:The Patlak graphical method is widely used in parametric imaging for modeling irreversible radiotracer kinetics in dynamic PET. The net influx rate of radiotracer can be determined from the slope of the Patlak plot. The implementation of the standard Patlak method requires the knowledge of full-time input function fro...

journal_title：Physics in medicine and biology

authors： Zuo Y,Qi J,Wang G

更新日期：2018-08-10 00:00:00

abstract：:The scope of this work was to develop a synthetic single crystal diamond dosimeter (SCDD-Pro) for accurate relative dose measurements of clinical proton beams in water. Monte Carlo simulations were carried out based on the MCNPX code in order to investigate and reduce the dose curve perturbation caused by the SCDD-Pro...

journal_title：Physics in medicine and biology

authors： Moignier C,Tromson D,de Marzi L,Marsolat F,García Hernández JC,Agelou M,Pomorski M,Woo R,Bourbotte JM,Moignau F,Lazaro D,Mazal A

更新日期：2017-07-07 00:00:00

abstract：:Quantification in cardiac mouse positron emission tomography (PET) imaging is limited by the imaging spatial resolution. Spillover of left ventricle (LV) myocardial activity into adjacent organs results in partial volume (PV) losses leading to underestimation of myocardial activity. A PV correction method was develope...

journal_title：Physics in medicine and biology

authors： Dumouchel T,Thorn S,Kordos M,DaSilva J,Beanlands RS,deKemp RA

更新日期：2012-07-07 00:00:00

abstract：:We have developed and tested a GSO (gadolinium oxyorthosilicate) position-sensitive gamma detector which can be used with positron and single-photon radionuclides for imaging breast cancer or sentinel lymph node detection. Because GSO has a relatively good energy resolution for annihilation gammas as well as low energ...

journal_title：Physics in medicine and biology

authors： Yamamoto S,Matsumoto K,Senda M

更新日期：2006-01-21 00:00:00

abstract：:In this paper we describe measurements of the contrast transfer function, modulation transfer function and point-spread function of an optical coherence tomography (OCT) imaging system through scattering layers having a dimension-less scattering depth over the range 0.2-6.9. The results were found to be insensitive to...

journal_title：Physics in medicine and biology

authors： Woolliams PD,Tomlins PH

更新日期：2011-05-07 00:00:00

abstract：:The Compton camera is an imaging device which has been proposed to detect prompt gammas (PGs) produced by proton-nuclear interactions within tissue during proton beam irradiation. Compton-based PG imaging has been developed to verify proton ranges because PG rays, particularly characteristic ones, have strong correlat...

journal_title：Physics in medicine and biology

authors： Huang HM,Liu CC,Jan ML,Lee MW

更新日期：2018-04-19 00:00:00

abstract：:An expression for the noise power spectrum of images reconstructed by the discrete filtered backprojection algorithm has been derived. The formulation explicitly includes sampling within the projections, angular sampling, and the two-dimensional sampling implicit in the discrete representation of the image. The effect...

journal_title：Physics in medicine and biology

authors： Kijewski MF,Judy PF

更新日期：1987-05-01 00:00:00

abstract：:In this paper, we present simulation studies for the second-generation MRI compatible SPECT system, MRC-SPECT-II, based on an inverted compound eye (ICE) gamma camera concept. The MRC-SPECT-II system consists of a total of 1536 independent micro-pinhole-camera-elements (MCEs) distributed in a ring with an inner diamet...

journal_title：Physics in medicine and biology

authors： Lai X,Meng LJ

更新日期：2018-02-12 00:00:00

abstract：:Registration of different imaging modalities such as CT, MRI, functional MRI (fMRI), positron (PET) and single photon (SPECT) emission tomography is used in many clinical applications. Determining the quality of any automatic registration procedure has been a challenging part because no gold standard is available to e...

journal_title：Physics in medicine and biology

authors： Ceylan C,van der Heide UA,Bol GH,Lagendijk JJ,Kotte AN

更新日期：2005-05-21 00:00:00

abstract：:The implementation of two algorithms for calculating dose distributions for radiation therapy treatment planning of intermediate energy proton beams is described. A pencil kernel algorithm and a depth penetration algorithm have been incorporated into a commercial three dimensional treatment planning system (Helax-TMS,...

journal_title：Physics in medicine and biology

authors： Russell KR,Isacsson U,Saxner M,Ahnesjö A,Montelius A,Grusell E,Dahlgren CV,Lorin S,Glimelius B

更新日期：2000-01-01 00:00:00

abstract：:A new thin-target method (patent pending) is described for portal imaging with low-energy (tens of keV) photons from a medical linear accelerator operating in a special mode. Low-energy photons are usually produced in the accelerator target, but are absorbed by the target and flattening filter, both made of medium- or...

journal_title：Physics in medicine and biology

authors： Tsechanski A,Bielajew AF,Faermann S,Krutman Y

更新日期：1998-08-01 00:00:00

abstract：:Gold nanoparticles (GNPs) have shown potential in recent years as a means of therapeutic dose enhancement in radiation therapy. However, a major challenge in moving towards clinical implementation is the exact characterisation of the dose enhancement they provide. Monte Carlo studies attempt to explore this property, ...

journal_title：Physics in medicine and biology

authors： Koger B,Kirkby C

更新日期：2016-03-07 00:00:00

abstract：:In this work, a methodology for using a smartphone camera, in conjunction with a light-tight box operating in reflective transmission mode, is investigated as a proof of concept for use as a film dosimetry system. An imaging system was designed to allow the camera of a smartphone to be used as a pseudo densitometer. T...

journal_title：Physics in medicine and biology

authors： Aland T,Jhala E,Kairn T,Trapp J

更新日期：2017-10-03 00:00:00

abstract：:In this study we present a three-dimensional (3D) reconstruction algorithm for magneto-acoustic tomography with magnetic induction (MAT-MI) based on the characteristics of the ultrasound transducer. The algorithm is investigated to solve the blur problem of the MAT-MI acoustic source image, which is caused by the ultr...

journal_title：Physics in medicine and biology

authors： Ma R,Zhou X,Zhang S,Yin T,Liu Z

更新日期：2016-12-21 00:00:00

abstract：:Current dosimetry protocols recommend the use of plane-parallel ionization chambers for the dosimetry of clinical electron beams. The necessary perturbation corrections p(wall) and p(cav) are assumed to be unity, independent of the depth of measurement and the energy of the primary electrons. To verify these assumptio...

journal_title：Physics in medicine and biology

authors： Zink K,Wulff J

更新日期：2009-04-21 00:00:00

abstract：:Ultrasound-based elastography including strain elastography, acoustic radiation force impulse (ARFI) imaging, point shear wave elastography and supersonic shear imaging (SSI) have been used to differentiate breast tumors among other clinical applications. The objective of this study is to extend a previously published...

journal_title：Physics in medicine and biology

authors： Wang Y,Peng B,Jiang J

更新日期：2017-03-07 00:00:00

abstract：:Time-of-flight (TOF) positron emission tomography (PET) technology has recently regained popularity in clinical PET studies for improving image quality and lesion detectability. Using TOF information, the spatial location of annihilation events is confined to a number of image voxels along each line of response, there...

journal_title：Physics in medicine and biology

authors： Mehranian A,Kotasidis F,Zaidi H

更新日期：2016-02-07 00:00:00

abstract：:Techniques for reducing computation time in 3D photon dose calculations are addressed with specific emphasis given to the convolution/superposition approach. A single polyenergetic superposition model calculating absorbed dose per incident photon fluence (Gy cm2) was developed in terms of TERMA and a total energy depo...

journal_title：Physics in medicine and biology

authors： Aspradakis MM,Redpath AT

更新日期：1997-08-01 00:00:00

abstract：:Laser interstitial thermotherapy (LITT) is employed to destroy tumors in organs, and its outcome strongly depends on the temperature distribution inside the treated tissue. The recent introduction of computed tomography (CT) scan thermometry, based on the CT number dependence of the tissue with temperature, overcomes ...

journal_title：Physics in medicine and biology

authors： Schena E,Saccomandi P,Giurazza F,Caponero MA,Mortato L,Di Matteo FM,Panzera F,Del Vescovo R,Beomonte Zobel B,Silvestri S

更新日期：2013-08-21 00:00:00

abstract：:Proton therapy potentially offers excellent dose conformality and reduction in integral dose. The superior dose distribution is, however, much more sensitive to the radiological depth along the beam path than for photon fields. Variations in this depth due to inaccurate planning calculation, setup uncertainty, respira...

journal_title：Physics in medicine and biology

authors： Lu HM

更新日期：2008-03-07 00:00:00

abstract：:Prenatal events such as intrauterine growth restriction and increased cardiovascular risk in later life have been shown to be associated with an increased intima-media thickness (aIMT) of the abdominal aorta in the fetus. In order to assess and manage atherosclerosis and cardiovascular disease risk in adults and child...

journal_title：Physics in medicine and biology

authors： Veronese E,Tarroni G,Visentin S,Cosmi E,Linguraru MG,Grisan E

更新日期：2014-11-07 00:00:00

abstract：:Finding fluence maps for intensity-modulated radiation therapy (IMRT) can be formulated as a multi-criteria optimization problem for which Pareto optimal treatment plans exist. To account for the dose-per-fraction effect of fractionated IMRT, it is desirable to exploit radiobiological treatment plan evaluation criteri...

journal_title：Physics in medicine and biology

authors： Hoffmann AL,den Hertog D,Siem AY,Kaanders JH,Huizenga H

更新日期：2008-11-21 00:00:00

abstract：:A 3D anatomical computational model is developed to assess thermal effects due to exposure to the electromagnetic field required to power a new investigational active implantable microvalve for the treatment of glaucoma. Such a device, located in the temporal superior eye quadrant, produces a filtering bleb, which is ...

journal_title：Physics in medicine and biology

authors： Schaumburg F,Guarnieri FA

更新日期：2017-05-07 00:00:00

abstract：:A pencil beam model for the calculation of the lateral scattering in water of protons for any therapeutic energy and depth is presented. It is based on the full Molière theory, taking into account the energy loss and the effects of mixtures and compounds. Concerning the electromagnetic part, the model has no free para...

journal_title：Physics in medicine and biology

authors： Bellinzona EV,Ciocca M,Embriaco A,Ferrari A,Fontana A,Mairani A,Parodi K,Rotondi A,Sala P,Tessonnier T

更新日期：2016-02-21 00:00:00

abstract：:Joint space morphology can be indicative of the risk, presence, progression, and/or treatment response of disease or trauma. We describe a novel methodology of characterizing joint space morphology in high-resolution 3D images (e.g. cone-beam CT (CBCT)) using a model based on elementary electrostatics that overcomes a...

journal_title：Physics in medicine and biology

authors： Cao Q,Thawait G,Gang GJ,Zbijewski W,Reigel T,Brown T,Corner B,Demehri S,Siewerdsen JH

更新日期：2015-02-07 00:00:00

abstract：:As a prerequisite for clinical treatments it was necessary to characterize the Elekta 1.5 T MRI-linac 7 MV FFF radiation beam. Following acceptance testing, beam characterization data were acquired with Semiflex 3D (PTW 31021), microDiamond (PTW 60019), and Farmer-type (PTW 30013 and IBA FC65-G) detectors in an Elekta...

journal_title：Physics in medicine and biology

authors： Woodings SJ,Bluemink JJ,de Vries JHW,Niatsetski Y,van Veelen B,Schillings J,Kok JGM,Wolthaus JWH,Hackett SL,van Asselen B,van Zijp HM,Pencea S,Roberts DA,Lagendijk JJW,Raaymakers BW

更新日期：2018-04-19 00:00:00