A technique for the fast calculation of three-dimensional photon dose distributions using the superposition model.

abstract：:Conventional molecular assessment of tissue through histology, if adapted to fresh thicker samples, has the potential to enhance cancer detection in surgical margins and monitoring of 3D cell culture molecular environments. However, in thicker samples, substantial background staining is common despite repeated rinsing...

journal_title：Physics in medicine and biology

authors： Xu X,Wang Y,Xiang J,Liu JTC,Tichauer KM

更新日期：2017-06-21 00:00:00

abstract：:Cylindrical ionization chambers with varying radii have been used to determine the displacement effect at distances between 10 mm and 40 mm from 60Co and 192Ir brachytherapy sources. Agreement with published values of the displacement factor for external 60Co beams is obtained. The shift between the centre of the ioni...

journal_title：Physics in medicine and biology

authors： Tölli H,Johansson KA

更新日期：1993-10-01 00:00:00

abstract：:The problem of fluorescence diffuse optical tomography consists in localizing fluorescent markers from near-infrared light measurements. Among the different available acquisition modalities, the time-resolved modality is expected to provide measurements of richer information content. To extract this information, the m...

journal_title：Physics in medicine and biology

authors： Ducros N,Hervé L,Da Silva A,Dinten JM,Peyrin F

更新日期：2009-12-07 00:00:00

abstract：:Our study aimed to quantitatively evaluate blood flow in the left ventricle (LV) of apical hypertrophic cardiomyopathy (APH) by combining wall thickness obtained from cardiac magnetic resonance imaging (MRI) and myocardial perfusion from single-photon emission computed tomography (SPECT). In this study, we considered ...

journal_title：Physics in medicine and biology

authors： Fukami T,Sato H,Wu J,Lwin TT,Yuasa T,Kawano S,Iida K,Akatsuka T,Hontani H,Takeda T,Tamura M,Yokota H

更新日期：2007-07-21 00:00:00

abstract：:The UK, European and IAEA protocols for breast dosimetry in mammography use tabulations of conversion factors, which relate measurements of incident air kerma to the mean glandular dose to the breast. To supplement the existing tabulations, a Monte Carlo computer program has been used to calculate conversion factors f...

journal_title：Physics in medicine and biology

authors： Dance DR,Young KC

更新日期：2014-05-07 00:00:00

abstract：:In recent codes of practice for reference dosimetry in clinical proton beams using ionization chambers, it is recommended to perform the measurement in a water phantom. However, in situations where the positioning accuracy is very critical, it could be more convenient to perform the measurement in a plastic phantom. I...

journal_title：Physics in medicine and biology

authors： Palmans H,Symons JE,Denis JM,de Kock EA,Jones DT,Vynckier S

更新日期：2002-09-07 00:00:00

abstract：:In fully three-dimensional PET imaging, iterative image reconstruction techniques usually outperform analytical algorithms in terms of image quality provided that an appropriate system model is used. In this study we concentrate on the calculation of an accurate system model for the YAP-(S)PET II small animal scanner,...

journal_title：Physics in medicine and biology

authors： Cecchetti M,Moehrs S,Belcari N,Del Guerra A

更新日期：2013-10-07 00:00:00

abstract：:An algorithm is described for three-dimensional whole-body (3DWB) image reconstruction in positron emission tomography. For whole-body applications, improvements to the popular fixed-axial-acceptance-angle technique are achieved by combining axially adjacent projection data available with a long-axis data set. Time-co...

journal_title：Physics in medicine and biology

authors： Cutler PD,Xu M

更新日期：1996-08-01 00:00:00

abstract：:We present a method based on spectral theory for the shape analysis of carpal bones of the human wrist. We represent the cortical surface of the carpal bone in a coordinate system based on the eigensystem of the two-dimensional Helmholtz equation. We employ a metric--global point signature (GPS)--that exploits the sca...

journal_title：Physics in medicine and biology

authors： Chaudhari AJ,Leahy RM,Wise BL,Lane NE,Badawi RD,Joshi AA

更新日期：2014-02-21 00:00:00

abstract：:Hair loss is a feared side effect of chemotherapy treatment. It may be prevented by cooling the scalp during administration of cytostatics. The supposed mechanism is that by cooling the scalp, both temperature and perfusion are diminished, affecting drug supply and drug uptake in the hair follicle. However, the effect...

journal_title：Physics in medicine and biology

authors： Janssen FE,Van Leeuwen GM,Van Steenhoven AA

更新日期：2005-09-07 00:00:00

abstract：:The purpose of this study was to apply a novel method of multiscale echo texture analysis for distinguishing benign (hemangiomas) from malignant (hepatocellular carcinomas (HCCs) and metastases) focal liver lesions in B-mode ultrasound images. In this method, regions of interest (ROIs) extracted from within the lesion...

journal_title：Physics in medicine and biology

authors： Yoshida H,Casalino DD,Keserci B,Coskun A,Ozturk O,Savranlar A

更新日期：2003-11-21 00:00:00

abstract：:We describe a radiation therapy treatment plan optimization method that explicitly considers the effects of interfraction organ motion through optimization on the clinical target volume (CTV), and investigate how it compares to conventional planning using a planning target volume (PTV). The method uses simulated treat...

journal_title：Physics in medicine and biology

authors： Fredriksson A,Engwall E,Andersson B

更新日期：2020-12-21 00:00:00

abstract：:Electrical properties (EP), namely conductivity and permittivity, can provide endogenous contrast for tissue characterization. Using electrical property tomography (EPT), maps of EP can be generated from conventional MRI data. This report investigates the feasibility and accuracy of EPT at 21.1 T for multiple RF coils...

journal_title：Physics in medicine and biology

authors： Amouzandeh G,Mentink-Vigier F,Helsper S,Bagdasarian FA,Rosenberg JT,Grant SC

更新日期：2020-02-28 00:00:00

abstract：:Several papers have recently addressed the issue of estimating chromophore concentration in optoacoustic imaging (OAI) using multiple wavelengths. The choice of wavelengths obviously affects the accuracy and precision of the estimates. One might assume that the wavelengths that maximize the extinction coefficients of ...

journal_title：Physics in medicine and biology

authors： Modgil D,La Riviére PJ

更新日期：2010-12-07 00:00:00

abstract：:Although it is known that obesity has a profound effect on x-ray computed tomography (CT) image quality and patient organ dose, quantitative data describing this relationship are not currently available. This study examines the effect of obesity on the calculated radiation dose to organs and tissues from CT using newl...

journal_title：Physics in medicine and biology

authors： Ding A,Mille MM,Liu T,Caracappa PF,Xu XG

更新日期：2012-05-07 00:00:00

abstract：:We assume that the data bits of a pixel in digital images can be divided into signal and noise bits. The signal bits occupy the most significant part of the pixel and the noise bits the least significant part. The signal part of each pixel are correlated while the noise parts are uncorrelated. Two statistical methods,...

journal_title：Physics in medicine and biology

authors： Chuang KS,Huang HK

更新日期：1992-02-01 00:00:00

abstract：:Ring artifacts in cone beam computed tomography (CBCT) images are caused by pixel gain variations using flat-panel detectors, and may lead to structured non-uniformities and deterioration of image quality. The purpose of this study is to propose a method of general ring artifact removal in CBCT images. This method is ...

journal_title：Physics in medicine and biology

authors： Liang X,Zhang Z,Niu T,Yu S,Wu S,Li Z,Zhang H,Xie Y

更新日期：2017-07-07 00:00:00

abstract：:The purpose of this study was to develop a method to simulate breathing motion induced interplay effects for volumetric modulated arc therapy (VMAT), to verify the proposed method with measurements, and to use the method to investigate how interplay effects vary with different patient- and machine specific parameters....

journal_title：Physics in medicine and biology

authors： Edvardsson A,Nordström F,Ceberg C,Ceberg S

更新日期：2018-04-19 00:00:00

abstract：:A step and shoot sequencer was developed that can be integrated into an IMRT optimization algorithm. The method uses non-uniform fluence steps and is adopted to the constraints of an MLC. It consists of a clustering, a smoothing and a segmentation routine. The performance of the algorithm is demonstrated for eight mat...

journal_title：Physics in medicine and biology

authors： Bär W,Alber M,Nüsslin F

更新日期：2001-07-01 00:00:00

abstract：:Due to high noise levels in the voxel kinetics, development of reliable parametric imaging algorithms remains one of most active areas in dynamic brain PET imaging, which in the vast majority of cases involves receptor/transporter studies with reversibly binding tracers. As such, the focus of this work has been to dev...

journal_title：Physics in medicine and biology

authors： Rahmim A,Zhou Y,Tang J,Lu L,Sossi V,Wong DF

更新日期：2012-02-07 00:00:00

abstract：:Radiotherapy treatment planning is associated with uncertainties. Examples are uncertainties in the tumour location due to organ movement or the inter/intra observer variability in target definition. Different approaches to incorporate uncertainties into IMRT optimization have been proposed. In this note, we point out...

journal_title：Physics in medicine and biology

authors： Unkelbach J,Oelfke U

更新日期：2006-12-07 00:00:00

abstract：:A two-probe technique has been developed to measure 125I in the thyroid. In this technique simultaneous emissions from a source are detected as coincidence events between two probes rather than as a sum peak in a single probe (the sum peak method). The background count rate when counting coincidence events between pro...

journal_title：Physics in medicine and biology

authors： Burns PA,Peggie JR

更新日期：1980-05-01 00:00:00

abstract：:An accurate, low noise estimate of photon attenuation in the subject is required for quantitative microPET studies of molecular tracer distributions in vivo. In this work, several transmission-based measurement techniques were compared, including coincidence mode with and without rod windowing, singles mode with two d...

journal_title：Physics in medicine and biology

authors： Lehnert W,Meikle SR,Siegel S,Newport D,Banati RB,Rosenfeld AB

更新日期：2006-08-21 00:00:00

abstract：:W (the average energy to form an ion pair) for 5.4 MeV 241Am alpha particles in a Rossi-type tissue-equivalent (TE) gas, argon and methane was determined to an accuracy better than 0.2% using a new automated data handling system. A vibrating reed electrometer and current digitiser were used to measure the current prod...

journal_title：Physics in medicine and biology

authors： Krieger GL,Baum JW,Varma MN,Beach JL

更新日期：1979-03-01 00:00:00

abstract：:The total system error (TSE) of a CyberKnife® system was measured using two phantom-based methods and one patient-based method. The standard radiochromic film (RCF) end-to-end (E2E) test using an anthropomorphic head and neck phantom and isocentric treatment delivery was used with the 6Dskull, Fiducial and Xsight® spi...

journal_title：Physics in medicine and biology

authors： Pantelis E,Moutsatsos A,Antypas C,Zoros E,Pantelakos P,Lekas L,Romanelli P,Zourari K,Hourdakis CJ

更新日期：2018-08-20 00:00:00

abstract：:Monte Carlo simulation techniques are applied to track the annihilation photons from positron decay, and store the photon histories. Reasonably realistic models of the isotope distribution in the brain and heart during typical PET studies, as well as the traditional phantoms used for measuring PET scanner performance ...

journal_title：Physics in medicine and biology

authors： Thompson CJ,Moreno-Cantu J,Picard Y

更新日期：1992-03-01 00:00:00

abstract：:Ultrasound in the low megahertz frequency range is used by physiotherapists to treat a variety of conditions. The treatments reduce swelling, reduce pain and increase movement at joints. Ultrasound is now also beginning to be used to treat malignant tumours. The tumours are heated to temperatures between 42 degrees an...

journal_title：Physics in medicine and biology

authors： Quan KM,Shiran M,Watmough DJ

更新日期：1989-11-01 00:00:00

abstract：:For quantitative measurements of small animals such as mice or rats, a compact and high sensitivity continuous blood sampling detector is required because their blood sampling volume is limited. For this purpose we have developed and tested a new positron detector. The positron detector uses a pair of dual-layer thin ...

journal_title：Physics in medicine and biology

authors： Yamamoto S,Imaizumi M,Shimosegawa E,Kanai Y,Sakamoto Y,Minato K,Shimizu K,Senda M,Hatazawa J

更新日期：2010-07-07 00:00:00

abstract：:Input functions required for positron emission tomography (PET) tracer kinetic modeling are often obtained from arterial blood. In some situations, using short-lived radiotracers, e.g. [(15)O]water, rapid sample handling is required. A method used at several facilities is to pump blood through a detector system at a c...

journal_title：Physics in medicine and biology

authors： Laymon CM,Sashin D,Carney JP,Ruszkiewicz J,Altenburger D,Becker CR,Lopresti BJ,Mason NS,Mountz JM,Price JC,Schavey R,Mathis CA

更新日期：2008-01-21 00:00:00

abstract：:This study presents a new approach to accurately account for the medium-dependent effect in model-based dose calculations for kilovoltage (kV) x-rays. This approach is based on the hypothesis that the correction factors needed to convert dose from model-based dose calculations to absorbed dose-to-medium depend on both...

journal_title：Physics in medicine and biology

authors： Pawlowski JM,Ding GX

更新日期：2011-07-07 00:00:00