A model for the accurate computation of the lateral scattering of protons in water.

Abstract:

:A pencil beam model for the calculation of the lateral scattering in water of protons for any therapeutic energy and depth is presented. It is based on the full Molière theory, taking into account the energy loss and the effects of mixtures and compounds. Concerning the electromagnetic part, the model has no free parameters and is in very good agreement with the FLUKA Monte Carlo (MC) code. The effects of the nuclear interactions are parametrized with a two-parameter tail function, adjusted on MC data calculated with FLUKA. The model, after the convolution with the beam and the detector response, is in agreement with recent proton data in water from HIT. The model gives results with the same accuracy of the MC codes based on Molière theory, with a much shorter computing time.

journal_name

Phys Med Biol

authors

Bellinzona EV,Ciocca M,Embriaco A,Ferrari A,Fontana A,Mairani A,Parodi K,Rotondi A,Sala P,Tessonnier T

doi

10.1088/0031-9155/61/4/N102

subject

Has Abstract

pub_date

2016-02-21 00:00:00

pages

N102-17

issue

4

eissn

0031-9155

issn

1361-6560

journal_volume

61

pub_type

杂志文章
  • Reconstructing uniformly attenuated rotating slant-hole SPECT projection data using the DBH method.

    abstract::This work applies a previously developed analytical algorithm to the reconstruction problem in a rotating multi-segment slant-hole (RMSSH) SPECT system. The RMSSH collimator has greater detection efficiency than the parallel-hole collimator with comparable spatial resolution at the expense of limited common volume-of-...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/13/024

    authors: Huang Q,Xu J,Tsui BM,Gullberg GT

    更新日期:2009-07-07 00:00:00

  • An automated method for adaptive radiation therapy for prostate cancer patients using continuous fiducial-based tracking.

    abstract::Electromagnetic tracking technology is primarily used for continuous prostate localization during radiotherapy, but offers potential value for evaluation of dosimetric coverage and adequacy of treatment for dynamic targets. We developed a highly automated method for daily computation of cumulative dosimetric effects o...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/55/1/005

    authors: Noel CE,Santanam L,Olsen JR,Baker KW,Parikh PJ

    更新日期:2010-01-07 00:00:00

  • Modelling of the dielectric properties of normal and irradiated skin.

    abstract::We have shown that irradiation changes the dielectric properties of human skin at radiofrequencies. Both the dielectric constant and the conductivity of the irradiated skin decrease, especially at low frequencies. The experimental data were analysed using two bioelectric models. Relevant dielectric parameters were det...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/39/6/001

    authors: Tamura T,Tenhunen M,Lahtinen T,Repo T,Schwan HP

    更新日期:1994-06-01 00:00:00

  • Out-of-field doses from pediatric craniospinal irradiations using 3D-CRT, IMRT, helical tomotherapy and electron-based therapy.

    abstract::Medulloblastoma treatment involves irradiation of the entire central nervous system, i.e. craniospinal irradiation (CSI). This is associated with the significant exposure of large volumes of healthy tissue and there is growing concern regarding treatment-associated side effects. The current study compares out-of-field...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa6c9e

    authors: De Saint-Hubert M,Verellen D,Poels K,Crijns W,Magliona F,Depuydt T,Vanhavere F,Struelens L

    更新日期:2017-07-07 00:00:00

  • The impact of calibration phantom errors on dual-energy digital mammography.

    abstract::Microcalcification is one of the earliest and main indicators of breast cancer. Because dual-energy digital mammography could suppress the contrast between the adipose and glandular tissues of the breast, it is considered a promising technique that will improve the detection of microcalcification. In dual-energy digit...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/22/004

    authors: Mou X,Chen X,Sun L,Yu H,Ji Z,Zhang L

    更新日期:2008-11-21 00:00:00

  • Dielectric properties of ocular tissues in the supercooled and frozen states.

    abstract::Values of the relative permittivity and conductivity of the rabbit retina and lens have been measured between 10 MHz and 10 GHz over the temperature range 20 to -20 degrees C. As the temperature was lowered from 20 degrees C the dielectric parameters changed smoothly until -9 degrees C where freezing occurred. At this...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/30/9/009

    authors: Gabriel C,Grant EH

    更新日期:1985-09-01 00:00:00

  • Benchmarking GATE/Geant4 for 16O ion beam therapy.

    abstract::Oxygen ([Formula: see text]) ions are a potential alternative to carbon ions in ion beam therapy. Their enhanced linear energy transfer indicates a higher relative biological effectiveness and a reduced oxygen enhancement ratio. Due to the limited availability of [Formula: see text] ion beams, Monte Carlo (MC) transpo...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa807e

    authors: Resch AF,Fuchs H,Georg D

    更新日期:2017-09-05 00:00:00

  • A mathematical model of the biologically effective dose of solar UVA received by patients undergoing oral psoralen photochemotherapy for psoriasis.

    abstract::A theoretical analysis is presented of the biologically effective dose of the solar long wave ultraviolet radiation (UVA) received by patients who are being treated for psoriasis by oral psoralen photochemotherapy. It is shown that patients treated during the summer months in the UK may well receive a UV dose which is...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/26/6/011

    authors: Diffey BL

    更新日期:1981-11-01 00:00:00

  • Fibre-optic sensors in health care.

    abstract::Biomedical fibre-optic sensors are attractive for the measurement of physical, chemical and biochemical parameters and for spectral measurements directly performed on the patient. An overview of fibre-optic sensors for in vivo monitoring is given, with particular attention paid to the advantages that these sensors are...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1088/0031-9155/42/5/015

    authors: Mignani AG,Baldini F

    更新日期:1997-05-01 00:00:00

  • Skin dose in chest wall radiotherapy with bolus: a Monte Carlo study.

    abstract::Monte Carlo simulations are used to investigate skin dose resulting from chest wall radiotherapy with bolus. A simple model of a female thorax is developed, which includes a 2 mm-thick skin layer. Two representative 6 MV source models are considered: a tangents source model consisting of a parallel opposed pair of med...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab95dc

    authors: Oliver PAK,Monajemi TT

    更新日期:2020-08-11 00:00:00

  • Reducing 4DCBCT imaging time and dose: the first implementation of variable gantry speed 4DCBCT on a linear accelerator.

    abstract::Four dimensional cone beam computed tomography (4DCBCT) uses a constant gantry speed and imaging frequency that are independent of the patient's breathing rate. Using a technique called respiratory motion guided 4DCBCT (RMG-4DCBCT), we have previously demonstrated that by varying the gantry speed and imaging frequency...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/62/11/4300

    authors: O'Brien RT,Stankovic U,Sonke JJ,Keall PJ

    更新日期:2017-06-07 00:00:00

  • Impact of free-breathing CT on quantitative measurements of static and quiescent period-gated PET Images.

    abstract::Measurements of standardized uptake values (SUV) can vary due to many causes, including respiratory motion. Various methodologies have been introduced to correct for motion in PET, with quiescent-period-gated (QPG) PET being the most popular approach. QPG has been shown to improve PET image quantification compared to ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab1cdd

    authors: Meier JG,Einstein SA,Diab RH,Erasmus LJ,Xu G,Mawlawi OR

    更新日期:2019-05-16 00:00:00

  • A novel technique for measuring the low-dose envelope of pencil-beam scanning spot profiles.

    abstract::To investigate the profile measurement capabilities of an IBA-Dosimetry scintillation detector and to assess its feasibility for determining the low-intensity tails of pencil-beam scanning spots, the responses of the scintillation detector and Gafchromic EBT2 film to a 115 MeV proton spot were measured in-air at the i...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/12/N171

    authors: Lin L,Ainsley CG,Mertens T,De Wilde O,Talla PT,McDonough JE

    更新日期:2013-06-21 00:00:00

  • Front-illuminated versus back-illuminated photon-counting CCD-based gamma camera: important consequences for spatial resolution and energy resolution.

    abstract::Charge-coupled devices (CCDs) coupled to scintillation crystals can be used for high-resolution imaging with x-rays and gamma rays. When the CCD images can be read out fast enough, the energy and interaction position of individual gamma quanta can be estimated by a real-time image analysis of the scintillation light f...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/52/8/N01

    authors: Heemskerk JW,Westra AH,Linotte PM,Ligtvoet KM,Zbijewski W,Beekman FJ

    更新日期:2007-04-21 00:00:00

  • Noise reduction and convergence of Bayesian algorithms with blobs based on the Huber function and median root prior.

    abstract::Iterative image reconstruction algorithms have the potential to produce low noise images. Early stopping of the iteration process is problematic because some features of the image may converge slowly. On the other hand, there may be noise build-up with increased number of iterations. Therefore, we examined the stabili...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/49/20/004

    authors: Chlewicki W,Hermansen F,Hansen SB

    更新日期:2004-10-21 00:00:00

  • Dielectric studies on the reaction of the intracellular matter of fish red blood cells to detergent toxicity.

    abstract::Results from dielectric studies on the freshwater fish Cyprinus carpio exposed to a sublethal concentration of sodium alkyl benzene sulphonate were compared with those from untreated control fish; recovery from the test solution was also checked. The influence of the anionic detergent on the intracellular matter of fi...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/29/5/005

    authors: Bielinska I,Terlecki J

    更新日期:1984-05-01 00:00:00

  • An investigation of factors affecting the accuracy of in vivo measurements of skin pigments by reflectance spectrophotometry.

    abstract::Factors affecting the accuracy of the in vivo measurement of cutaneous pigments and blood oxygenation by reflectance spectrophotometry have been examined. It was found that stray light, the amounts of haemoglobin and melanin, and the level of blood oxygenation all contributed to the measured reflectance and had to be ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/35/9/009

    authors: Hajizadeh-Saffar M,Feather JW,Dawson JB

    更新日期:1990-09-01 00:00:00

  • Dosimetric verification of open asymmetric photon fields calculated with a treatment planning system based on dose-to-energy-fluence concepts.

    abstract::Output normalized dose profiles for asymmetric open photon fields has been calculated using a commercial treatment planning system (TPS) based on a dose-to-energy-fluence concept. The model does not require any additional measurements for off-axis fields. Calculations are compared with measurements for quadratic field...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/41/8/003

    authors: Hurkmans C,Knöös T,Nilsson P

    更新日期:1996-08-01 00:00:00

  • Reducing scan angle using adaptive prior knowledge for a limited-angle intrafraction verification (LIVE) system for conformal arc radiotherapy.

    abstract::The purpose of this study is to develop an adaptive prior knowledge guided image estimation technique to reduce the scan angle needed in the limited-angle intrafraction verification (LIVE) system for 4D-CBCT reconstruction. The LIVE system has been previously developed to reconstruct 4D volumetric images on-the-fly du...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa6913

    authors: Zhang Y,Yin FF,Zhang Y,Ren L

    更新日期:2017-05-07 00:00:00

  • Experimental 3D dosimetry around a high-dose-rate clinical 192Ir source using a polyacrylamide gel (PAG) dosimeter.

    abstract::It is well known that the experimental dosimetry of brachytherapy sources presents a challenge. Depending on the particular-dosimeter used, measurements can suffer from poor spatial resolution (ion chambers), lack of 3D information (film) or errors due to the presence of the dosimeter itself distorting the radiation f...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/44/10/305

    authors: McJury M,Tapper PD,Cosgrove VP,Murphy PS,Griffin S,Leach MO,Webb S,Oldham M

    更新日期:1999-10-01 00:00:00

  • High-energy x-ray Talbot-Lau radiography of a human knee.

    abstract::We report on a radiographic measurement of an ex vivo human knee using a grating-based phase-contrast imaging setup and a medical x-ray tube at a tube voltage of 70 kV. The measurement has been carried out using a Talbot-Lau setup that is suitable to achieve a high visibility in the energy regime of medical imaging. I...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa7721

    authors: Horn F,Gelse K,Jabari S,Hauke C,Kaeppler S,Ludwig V,Meyer P,Michel T,Mohr J,Pelzer G,Rieger J,Riess C,Seifert M,Anton G

    更新日期:2017-08-01 00:00:00

  • Including robustness in multi-criteria optimization for intensity-modulated proton therapy.

    abstract::We present a method to include robustness in a multi-criteria optimization (MCO) framework for intensity-modulated proton therapy (IMPT). The approach allows one to simultaneously explore the trade-off between different objectives as well as the trade-off between robustness and nominal plan quality. In MCO, a database...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/57/3/591

    authors: Chen W,Unkelbach J,Trofimov A,Madden T,Kooy H,Bortfeld T,Craft D

    更新日期:2012-02-07 00:00:00

  • Ion concentration and haematocrit as determinants of impedance in an erythrocyte suspension model of renal medullary tissue.

    abstract::In order to analyse the respective roles of ion concentration and fractional volume of the interstitial compartment as determinants of the impedance, Z, of renal medullary tissue, a model was needed in which both these factors could be varied independently. An array of blood cell suspensions ions in saline (different ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/35/11/011

    authors: Niewiadomski W,Sadowski J,Badzyńska B,Rasmussen SN

    更新日期:1990-11-01 00:00:00

  • Coronary CT angiography (cCTA): automated registration of coronary arterial trees from multiple phases.

    abstract::Coronary computed tomography angiography (cCTA) is a commonly used imaging modality for the evaluation of coronary artery disease. cCTA is generally reconstructed in multiple cardiac phases because different coronary arteries may be better visualized in some phases than in others due to the periodic cardiac motion. We...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/59/16/4661

    authors: Hadjiiski L,Zhou C,Chan HP,Chughtai A,Agarwal P,Kuriakose J,Kazerooni E,Wei J,Patel S

    更新日期:2014-08-21 00:00:00

  • Denoising of multi b-value diffusion-weighted MR images using deep image prior.

    abstract::The clinical value of multiple b-value diffusion-weighted (DW) magnetic resonance imaging (MRI) has been shown in many studies. However, DW-MRI often suffers from low signal-to-noise ratio, especially at high b-values. To address this limitation, we present an image denoising method based on the concept of deep image ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab8105

    authors: Lin YC,Huang HM

    更新日期:2020-05-11 00:00:00

  • Deformable and durable phantoms with controlled density of scatterers.

    abstract::We have developed deformable and durable optical tissue phantoms with a simple and well-defined microstructure including a novel combination of scatterers and a matrix material. These were developed for speckle and elastography investigations in optical coherence tomography, but should prove useful in many other field...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/13/N01

    authors: Bisaillon CE,Lamouche G,Maciejko R,Dufour M,Monchalin JP

    更新日期:2008-07-07 00:00:00

  • Changes in optical properties of ex vivo rat prostate due to heating.

    abstract::This study examines the effectiveness of a single, first-order Arrhenius process in accurately modelling the thermally induced changes in the optical properties, particularly the reduced scattering coefficient, mu(s)', and the absorption coefficient, mu(a), of ex vivo rat prostate. Recent work has shown that mu(s)' ca...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/45/5/319

    authors: Skinner MG,Everts S,Reid AD,Vitkin IA,Lilge L,Sherar MD

    更新日期:2000-05-01 00:00:00

  • The sliding slit test for dynamic IMRT: a useful tool for adjustment of MLC related parameters.

    abstract::For treatments with dynamic intensity modulated radiotherapy (IMRT), the adjustment of multileaf collimator (MLC) parameters affecting both the optimization algorithm and dose distributions is crucial. The main parameters characterizing the MLC are the transmission (T) and the dosimetric leaf separation (DLS). The aim...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/50/4/001

    authors: Chauvet I,Petitfils A,Lehobey C,Kristner JY,Brunet Y,Lembrez R,Gaboriaud G,Mazal A,Zefkili S,Rosenwald JC

    更新日期:2005-02-21 00:00:00

  • Radiation damage, repopulation and cell recovery analysis of in vitro tumour cell megacolony culture data using a non-Poissonian cell repopulation TCP model.

    abstract::The effects of radiation damage, tumour repopulation and cell sublethal damage repair and the possibility of extracting information about the model parameters describing them are investigated in this work. Previously published data on two different cultured cell lines were analysed with the help of a tumour control pr...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/50/13/006

    authors: Stavrev P,Weldon M,Warkentin B,Stavreva N,Fallone BG

    更新日期:2005-07-07 00:00:00

  • Recovery of total I-131 activity within focal volumes using SPECT and 3D OSEM.

    abstract::We experimentally investigated the SPECT recovery of I-131 activity in multiple spheres located simultaneously at different locations within a cylindrical phantom that had an elliptical cross section. The sphere volumes ranged from 209 cc down to 4.2 cc. A Prism 3000 camera and two types of parallel-hexagonal-hole col...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/52/3/017

    authors: Koral KF,Yendiki A,Dewaraja YK

    更新日期:2007-02-07 00:00:00